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The map label for this gene is gmhA [H]

Identifier: 186474894

GI number: 186474894

Start: 132877

End: 133464

Strand: Direct

Name: gmhA [H]

Synonym: Bphy_0124

Alternate gene names: 186474894

Gene position: 132877-133464 (Clockwise)

Preceding gene: 186474893

Following gene: 186474895

Centisome position: 3.82

GC content: 62.07

Gene sequence:

>588_bases
ATGTCAGTCGAACGCATTCAACAACACTTCCGCGACAGCGCGGCAGTCACACTCGCAGCACTTGAAGCGCTGTCGATGCC
GATCGCGGCGGCCGTCGACGCGATGTTTGCCGCACTTGCAAACGGTAACAAGATTCTGACGTGCGGCAATGGCGGCTCCG
CTGCCGACGCGCAATACTTTGCCGCCGAACTGATCGGCGGCTTCGAGCGCGAGCGTCCCGCATTGCCGGCCATCGCGCTG
ACGACGGATTCTTCGGTCATCACGGGCATCGCCAACGATGCCTCGCTCGACCAGATTTTCGCGACGCAGGTTCGCGCGCT
CGGCCAGCCCGGCGACGTGCTGCTTGCTATTTCGACGTCGGGCAATCCCGCCAATGTTCTCGCTGCCATCGAAGACGCGC
ACGACCGGGAGATGATCGTGGTAGCGCTGTCGGGCACGGGCGGCGGAAAGATCAACGAAGTGCTGCACGACACCGACATC
CACATTTGCGCACCGTCCGATCGCACGGCGCGCGTGCAGGAAGTGCATCTGTTGACGATCCATAGTCTGTGCGACGGCAT
CGATGCCATGTTGCTCGGCGAAGAATGA

Upstream 100 bases:

>100_bases
CGGTCGGCGCGGCAGCGGACAATCGCACGGGGAAGCGCCCACGTCCAATTGAACCAGCGCTGCCGGGCGGGCGGCGCAAG
CAGTACACCATAGAGAGTCG

Downstream 100 bases:

>100_bases
TTCCGAAGGAGAGTGAGTTGATGAGCGCATATCGCGTGAAGAGTACGTTCGTGAGAACCACGCTGGTGGTGGGTCTCGTC
GCGGGGCTGGCCGCGACGTT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSVERIQQHFRDSAAVTLAALEALSMPIAAAVDAMFAALANGNKILTCGNGGSAADAQYFAAELIGGFERERPALPAIAL
TTDSSVITGIANDASLDQIFATQVRALGQPGDVLLAISTSGNPANVLAAIEDAHDREMIVVALSGTGGGKINEVLHDTDI
HICAPSDRTARVQEVHLLTIHSLCDGIDAMLLGEE

Sequences:

>Translated_195_residues
MSVERIQQHFRDSAAVTLAALEALSMPIAAAVDAMFAALANGNKILTCGNGGSAADAQYFAAELIGGFERERPALPAIAL
TTDSSVITGIANDASLDQIFATQVRALGQPGDVLLAISTSGNPANVLAAIEDAHDREMIVVALSGTGGGKINEVLHDTDI
HICAPSDRTARVQEVHLLTIHSLCDGIDAMLLGEE
>Mature_194_residues
SVERIQQHFRDSAAVTLAALEALSMPIAAAVDAMFAALANGNKILTCGNGGSAADAQYFAAELIGGFERERPALPAIALT
TDSSVITGIANDASLDQIFATQVRALGQPGDVLLAISTSGNPANVLAAIEDAHDREMIVVALSGTGGGKINEVLHDTDIH
ICAPSDRTARVQEVHLLTIHSLCDGIDAMLLGEE

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=192, Percent_Identity=52.0833333333333, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1786416, Length=152, Percent_Identity=45.3947368421053, Blast_Score=123, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20200; Mature: 20069

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVERIQQHFRDSAAVTLAALEALSMPIAAAVDAMFAALANGNKILTCGNGGSAADAQYF
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
AAELIGGFERERPALPAIALTTDSSVITGIANDASLDQIFATQVRALGQPGDVLLAISTS
HHHHHCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECC
GNPANVLAAIEDAHDREMIVVALSGTGGGKINEVLHDTDIHICAPSDRTARVQEVHLLTI
CCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHCCCCEEEECCCCCCCEEHHHHEEHH
HSLCDGIDAMLLGEE
HHHHCCCHHEEECCC
>Mature Secondary Structure 
SVERIQQHFRDSAAVTLAALEALSMPIAAAVDAMFAALANGNKILTCGNGGSAADAQYF
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
AAELIGGFERERPALPAIALTTDSSVITGIANDASLDQIFATQVRALGQPGDVLLAISTS
HHHHHCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECC
GNPANVLAAIEDAHDREMIVVALSGTGGGKINEVLHDTDIHICAPSDRTARVQEVHLLTI
CCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHCCCCEEEECCCCCCCEEHHHHEEHH
HSLCDGIDAMLLGEE
HHHHCCCHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA