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The map label for this gene is ybdL [H]

Identifier: 186474786

GI number: 186474786

Start: 16752

End: 17906

Strand: Direct

Name: ybdL [H]

Synonym: Bphy_0014

Alternate gene names: 186474786

Gene position: 16752-17906 (Clockwise)

Preceding gene: 186474785

Following gene: 186474787

Centisome position: 0.48

GC content: 60.87

Gene sequence:

>1155_bases
ATGCAGAGCGCTTTGCAAGCCCGCTCGAAATTGCCGGACGTCGGCACGACGATTTTCACCGTCATCGGCCAGCTGGCCGC
CGAACATAACGCGTTGAACCTCTCTCAAGGCGCACCGAATTTCGCGCCTGACGAGGCGCTCGTCGACGGCGTGACGAAGG
CAATGCGCGCGGGACACAACCAGTACGCGCCGATGGCGGGCATTGGGGCATTGCGTTCCGCGCTGGCCGCGAAGATCGAA
ACGCTGTACGGCGTGCACTACGATCCGTCCACGGAAGTGACCGTGATCGCGAGCGCGAGCGAAGGGCTCTATTCGACGAT
CAGCGCGCTCGTGCATCCCGGCGACGAAGTGATCTACTTCGAGCCGTCGTTCGACAGCTATGCGCCAATCGTGCGTCTGC
AAGGCGCGAAGCCGGTTCCGATCAAGCTGTCCGCGCCCAGTTTTCGCGTGAACTGGGATGAGGTGTCCGCAGCGATCACG
CCGAAGACGCGCATGATCATCGTCAACACGCCGCACAATCCCACCGCGACGATTTTCAGCGACGCGGATATCGAACGTCT
GAAGGCTGTGACGCGCAACACGGATATCGTGATTCTTTCCGATGAAGTGTACGAGCATGTCGTGTTCGACGGCGCGAAGC
ATCACAGCATGGCGCGCCATCGCGAACTGGCGGAGCGCAGCGTGATCGTGTCGTCGTTCGGCAAGTCGTATCACGTGACG
GGCTGGCGCGTCGGCTATTGCCTTGCACCCGCGGCGTTGATGGACGAGATTCGCAAGATCCATCAATTCATGGTGTTTTC
CGCCGACACGCCGATGCAGTATGCGTTCGTCGAGGCGCTGTCCGATCCGCAAAGCTATCTGGGCCTGTCCGACTTTTATC
AGCGCAAGCGCGATCTGCTCGCAAGCGAGTTGCGCGAGTCGCGCTTCGAACTATTGCCGAGCGAAGGCAGCTTCTTCATG
CTCGCGCGCTTTCGCGGCTTCTCGGATGAAAGCGACAGCGACTTCGTCCTGCGTTTGATCCGCGATGCGAAGGTCGCGAC
CATTCCGCTGTCGGCGTTCTACACGGACGCCACGGACGCCGGCGTGATCCGTCTGAGCTTTTCGAAGGACGACGACACGC
TGATCGAAGGCGCACGCCGTCTGCGTTCAATCTGA

Upstream 100 bases:

>100_bases
CGATTGTTCTCGTGCGTGCGTTGTTGCCTAATCGTACAAACTGAACGGGACCGACGCGCGATGCGCGGCCCGCCGATTTG
CAGCGAGAAGGAGGAATCTC

Downstream 100 bases:

>100_bases
CCGAGGGTCACGCGATGATGCAGCAATCGATCAAGGCCGCCGTCGTGCAGATGAGCAGCAGCGCCGATGTGCAGCAGAAC
CTCGGTGAGGCGCGCCGTTG

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MQSALQARSKLPDVGTTIFTVIGQLAAEHNALNLSQGAPNFAPDEALVDGVTKAMRAGHNQYAPMAGIGALRSALAAKIE
TLYGVHYDPSTEVTVIASASEGLYSTISALVHPGDEVIYFEPSFDSYAPIVRLQGAKPVPIKLSAPSFRVNWDEVSAAIT
PKTRMIIVNTPHNPTATIFSDADIERLKAVTRNTDIVILSDEVYEHVVFDGAKHHSMARHRELAERSVIVSSFGKSYHVT
GWRVGYCLAPAALMDEIRKIHQFMVFSADTPMQYAFVEALSDPQSYLGLSDFYQRKRDLLASELRESRFELLPSEGSFFM
LARFRGFSDESDSDFVLRLIRDAKVATIPLSAFYTDATDAGVIRLSFSKDDDTLIEGARRLRSI

Sequences:

>Translated_384_residues
MQSALQARSKLPDVGTTIFTVIGQLAAEHNALNLSQGAPNFAPDEALVDGVTKAMRAGHNQYAPMAGIGALRSALAAKIE
TLYGVHYDPSTEVTVIASASEGLYSTISALVHPGDEVIYFEPSFDSYAPIVRLQGAKPVPIKLSAPSFRVNWDEVSAAIT
PKTRMIIVNTPHNPTATIFSDADIERLKAVTRNTDIVILSDEVYEHVVFDGAKHHSMARHRELAERSVIVSSFGKSYHVT
GWRVGYCLAPAALMDEIRKIHQFMVFSADTPMQYAFVEALSDPQSYLGLSDFYQRKRDLLASELRESRFELLPSEGSFFM
LARFRGFSDESDSDFVLRLIRDAKVATIPLSAFYTDATDAGVIRLSFSKDDDTLIEGARRLRSI
>Mature_384_residues
MQSALQARSKLPDVGTTIFTVIGQLAAEHNALNLSQGAPNFAPDEALVDGVTKAMRAGHNQYAPMAGIGALRSALAAKIE
TLYGVHYDPSTEVTVIASASEGLYSTISALVHPGDEVIYFEPSFDSYAPIVRLQGAKPVPIKLSAPSFRVNWDEVSAAIT
PKTRMIIVNTPHNPTATIFSDADIERLKAVTRNTDIVILSDEVYEHVVFDGAKHHSMARHRELAERSVIVSSFGKSYHVT
GWRVGYCLAPAALMDEIRKIHQFMVFSADTPMQYAFVEALSDPQSYLGLSDFYQRKRDLLASELRESRFELLPSEGSFFM
LARFRGFSDESDSDFVLRLIRDAKVATIPLSAFYTDATDAGVIRLSFSKDDDTLIEGARRLRSI

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=418, Percent_Identity=31.3397129186603, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI169881279, Length=418, Percent_Identity=31.3397129186603, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI56713254, Length=396, Percent_Identity=30.050505050505, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI56713256, Length=396, Percent_Identity=30.050505050505, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI169881281, Length=300, Percent_Identity=30.6666666666667, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI4507369, Length=381, Percent_Identity=24.1469816272966, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=47.8835978835979, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=26.1707988980716, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788627, Length=382, Percent_Identity=26.4397905759162, Blast_Score=98, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=406, Percent_Identity=34.4827586206897, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71994476, Length=406, Percent_Identity=34.4827586206897, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17567369, Length=409, Percent_Identity=31.2958435207824, Blast_Score=200, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI17567663, Length=351, Percent_Identity=23.6467236467236, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=383, Percent_Identity=28.9817232375979, Blast_Score=167, Evalue=3e-42,
Organism=Drosophila melanogaster, GI28573069, Length=391, Percent_Identity=32.9923273657289, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24646114, Length=391, Percent_Identity=32.9923273657289, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI28573067, Length=391, Percent_Identity=32.9923273657289, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI28573065, Length=391, Percent_Identity=32.9923273657289, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI18859735, Length=355, Percent_Identity=25.9154929577465, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42314; Mature: 42314

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSALQARSKLPDVGTTIFTVIGQLAAEHNALNLSQGAPNFAPDEALVDGVTKAMRAGHN
CCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCC
QYAPMAGIGALRSALAAKIETLYGVHYDPSTEVTVIASASEGLYSTISALVHPGDEVIYF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGAKPVPIKLSAPSFRVNWDEVSAAITPKTRMIIVNTPHNPTATIFS
CCCCCCCCCEEEECCCCCCEEEECCCCEEEEHHHHHEEECCCEEEEEEECCCCCCEEEEC
DADIERLKAVTRNTDIVILSDEVYEHVVFDGAKHHSMARHRELAERSVIVSSFGKSYHVT
CCHHHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECC
GWRVGYCLAPAALMDEIRKIHQFMVFSADTPMQYAFVEALSDPQSYLGLSDFYQRKRDLL
CEEHHHHHCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
ASELRESRFELLPSEGSFFMLARFRGFSDESDSDFVLRLIRDAKVATIPLSAFYTDATDA
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEHHHEECCCCCC
GVIRLSFSKDDDTLIEGARRLRSI
CEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQSALQARSKLPDVGTTIFTVIGQLAAEHNALNLSQGAPNFAPDEALVDGVTKAMRAGHN
CCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCC
QYAPMAGIGALRSALAAKIETLYGVHYDPSTEVTVIASASEGLYSTISALVHPGDEVIYF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGAKPVPIKLSAPSFRVNWDEVSAAITPKTRMIIVNTPHNPTATIFS
CCCCCCCCCEEEECCCCCCEEEECCCCEEEEHHHHHEEECCCEEEEEEECCCCCCEEEEC
DADIERLKAVTRNTDIVILSDEVYEHVVFDGAKHHSMARHRELAERSVIVSSFGKSYHVT
CCHHHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECC
GWRVGYCLAPAALMDEIRKIHQFMVFSADTPMQYAFVEALSDPQSYLGLSDFYQRKRDLL
CEEHHHHHCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
ASELRESRFELLPSEGSFFMLARFRGFSDESDSDFVLRLIRDAKVATIPLSAFYTDATDA
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEHHHEECCCCCC
GVIRLSFSKDDDTLIEGARRLRSI
CEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]