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The map label for this gene is yafV [C]

Identifier: 186474787

GI number: 186474787

Start: 17921

End: 18763

Strand: Direct

Name: yafV [C]

Synonym: Bphy_0015

Alternate gene names: 186474787

Gene position: 17921-18763 (Clockwise)

Preceding gene: 186474786

Following gene: 186474788

Centisome position: 0.52

GC content: 67.14

Gene sequence:

>843_bases
ATGATGCAGCAATCGATCAAGGCCGCCGTCGTGCAGATGAGCAGCAGCGCCGATGTGCAGCAGAACCTCGGTGAGGCGCG
CCGTTGGGTTCAGCAAGCCGCGCGCGAGGGCGCCACGCTGATCTGCCTGCCCGAATACTTCTGCTGGATCGGCGACGGCG
AGATGCAGCGGGTCGCGCTTGCCGAATCGTTCGGCGATGGCCCAATTCAACGGACGCTTTCGGAACTGGCGCGCGAGACG
GGCACATGGCTGATCGGCGGTACGGTGCCGATCCGTCCGGCGCACGGGCCGCAGGTGGGCACGCACGCGTACAACACGTC
GCTCGTCTTCGATCCGGCGGGACAGTGCGCGGCGCGCTATGACAAGATCCATCTGTTCAGCTTCAACCAGGGTGCGGAGC
AGCATGCGGAAGGCGACACGATGGTCGGCGGCGACAGCATCAGCACCGCGCGGGGGCCGTTCGGCACGCTGCGGCTGTCG
GTGTGCTACGACTTGCGCTTTCCCGAGTTGTATCGCGCGGGGCCGGACGCCGACATCATCGCCGTGCCTGCAGCCTTCAC
CCATACGACGGGCCTCGCACATTGGGAACTGCTGCTGCGTGCGCGCGCCGTCGAAAATCAGGCCTTTGTGCTTGCATCCG
GCCAGTGCGGCACGCACTCGAACGGCTGGCGCACTTTTGGCCACAGTATGATCGTCGGGCCGTGGGGCGAGGTGCTCGCG
CGGCGCGACGACGAGCCCGGCATCGCGCTCGCGACGCTCACACAAAGCGCGCTCGACGAAGCGCGCGACCGTCTGCCGGT
GCTCGCGCATCGGCGCATCGCAACGCCGTCTGACGTGCGTTGA

Upstream 100 bases:

>100_bases
CCACGGACGCCGGCGTGATCCGTCTGAGCTTTTCGAAGGACGACGACACGCTGATCGAAGGCGCACGCCGTCTGCGTTCA
ATCTGACCGAGGGTCACGCG

Downstream 100 bases:

>100_bases
ACCGCATTGAACACAAGGGGAAGGAGATCGATGATGAAGCTGGTTAAGAGTCTGCTGATGCTGTCGTGCGGGTTCGCATC
GGTGGCGGCCGTGTCGGCGA

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MMQQSIKAAVVQMSSSADVQQNLGEARRWVQQAAREGATLICLPEYFCWIGDGEMQRVALAESFGDGPIQRTLSELARET
GTWLIGGTVPIRPAHGPQVGTHAYNTSLVFDPAGQCAARYDKIHLFSFNQGAEQHAEGDTMVGGDSISTARGPFGTLRLS
VCYDLRFPELYRAGPDADIIAVPAAFTHTTGLAHWELLLRARAVENQAFVLASGQCGTHSNGWRTFGHSMIVGPWGEVLA
RRDDEPGIALATLTQSALDEARDRLPVLAHRRIATPSDVR

Sequences:

>Translated_280_residues
MMQQSIKAAVVQMSSSADVQQNLGEARRWVQQAAREGATLICLPEYFCWIGDGEMQRVALAESFGDGPIQRTLSELARET
GTWLIGGTVPIRPAHGPQVGTHAYNTSLVFDPAGQCAARYDKIHLFSFNQGAEQHAEGDTMVGGDSISTARGPFGTLRLS
VCYDLRFPELYRAGPDADIIAVPAAFTHTTGLAHWELLLRARAVENQAFVLASGQCGTHSNGWRTFGHSMIVGPWGEVLA
RRDDEPGIALATLTQSALDEARDRLPVLAHRRIATPSDVR
>Mature_280_residues
MMQQSIKAAVVQMSSSADVQQNLGEARRWVQQAAREGATLICLPEYFCWIGDGEMQRVALAESFGDGPIQRTLSELARET
GTWLIGGTVPIRPAHGPQVGTHAYNTSLVFDPAGQCAARYDKIHLFSFNQGAEQHAEGDTMVGGDSISTARGPFGTLRLS
VCYDLRFPELYRAGPDADIIAVPAAFTHTTGLAHWELLLRARAVENQAFVLASGQCGTHSNGWRTFGHSMIVGPWGEVLA
RRDDEPGIALATLTQSALDEARDRLPVLAHRRIATPSDVR

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632350, Length=268, Percent_Identity=40.2985074626866, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI297632348, Length=268, Percent_Identity=40.2985074626866, Blast_Score=178, Evalue=4e-45,
Organism=Homo sapiens, GI5031947, Length=268, Percent_Identity=40.2985074626866, Blast_Score=178, Evalue=4e-45,
Organism=Homo sapiens, GI9910460, Length=271, Percent_Identity=36.5313653136531, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI297632346, Length=192, Percent_Identity=36.9791666666667, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1786412, Length=231, Percent_Identity=32.034632034632, Blast_Score=85, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17556280, Length=268, Percent_Identity=37.3134328358209, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6323383, Length=289, Percent_Identity=31.1418685121107, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322335, Length=302, Percent_Identity=30.4635761589404, Blast_Score=137, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17933642, Length=275, Percent_Identity=36, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21355835, Length=274, Percent_Identity=32.1167883211679, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30410; Mature: 30410

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQQSIKAAVVQMSSSADVQQNLGEARRWVQQAAREGATLICLPEYFCWIGDGEMQRVAL
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHEEEECCCCHHHHHH
AESFGDGPIQRTLSELARETGTWLIGGTVPIRPAHGPQVGTHAYNTSLVFDPAGQCAARY
HHHCCCCHHHHHHHHHHHHHCCEEEECCEEECCCCCCCCCCEEECCEEEECCCHHHHHHH
DKIHLFSFNQGAEQHAEGDTMVGGDSISTARGPFGTLRLSVCYDLRFPELYRAGPDADII
CEEEEEECCCCCHHHCCCCEEECCCCCCCCCCCCCEEEEEEEEECCCHHHHHCCCCCCEE
AVPAAFTHTTGLAHWELLLRARAVENQAFVLASGQCGTHSNGWRTFGHSMIVGPWGEVLA
EECCHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHCCEEEECCHHHHHH
RRDDEPGIALATLTQSALDEARDRLPVLAHRRIATPSDVR
CCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MMQQSIKAAVVQMSSSADVQQNLGEARRWVQQAAREGATLICLPEYFCWIGDGEMQRVAL
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHEEEECCCCHHHHHH
AESFGDGPIQRTLSELARETGTWLIGGTVPIRPAHGPQVGTHAYNTSLVFDPAGQCAARY
HHHCCCCHHHHHHHHHHHHHCCEEEECCEEECCCCCCCCCCEEECCEEEECCCHHHHHHH
DKIHLFSFNQGAEQHAEGDTMVGGDSISTARGPFGTLRLSVCYDLRFPELYRAGPDADII
CEEEEEECCCCCHHHCCCCEEECCCCCCCCCCCCCEEEEEEEEECCCHHHHHCCCCCCEE
AVPAAFTHTTGLAHWELLLRARAVENQAFVLASGQCGTHSNGWRTFGHSMIVGPWGEVLA
EECCHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHCCEEEECCHHHHHH
RRDDEPGIALATLTQSALDEARDRLPVLAHRRIATPSDVR
CCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]