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The map label for this gene is ygcA [C]

Identifier: 183222798

GI number: 183222798

Start: 3577088

End: 3578239

Strand: Reverse

Name: ygcA [C]

Synonym: LEPBI_I3458

Alternate gene names: 183222798

Gene position: 3578239-3577088 (Counterclockwise)

Preceding gene: 183222803

Following gene: 183222791

Centisome position: 99.4

GC content: 38.02

Gene sequence:

>1152_bases
ATGGAAAAGTTGCAGATTAAATTAGAAAAATGGGTCAATGGAGGCTACTGCCTCGCTCACCATGATGGCCATGCAGTGTT
CATTGAAGGTGGTCTTCCCGGTGAATTGGTAGACATAACTCTGACCAAACAAGGGAAGAAGGAATGGTTTGGAGTTGTTA
CATCGGTTTTGGAACCTTCCAAATTCAGAATTCCGTCGGACTGTCCTGTGTATTTGGAGTGCGGTGGTTGCAGTTATCGT
CATCTCCCCTATGAAGAAGAGTTGAAACTCAAAACCAATTTATTGGAATCCATGTTTCCCAAGTGGAAAGGCAAAACAGA
CGTAATCTTTGGACCAATGGAAGGTTATCGGAATAATGTCCAATGGCAAGTTGTTGGAAACGAAATCGGTTTTTTTGAGA
AAAATACCCATCAGATCGTTTCAAAGACGTCCACACTTTGTAAAAATGTCGATAAACGTCTATTAGTTGAAGATTCGAAA
ACCTTCCTGACCCAAAATACTAAACACCAAAAGAATCACACAAATCATAACCAAAAGTTTGGGAGATCCATTTCACTTAG
GCTTTCCAAAGAAAAAATTGTACAATATGATTTAGAGGAAACGGAAATAGAGGTTCTTGGAACTCAATTAAAAGTACCGG
CAAAAGGGTTTTTTCAAATCAACCAGTTCCTTTTAGAAACATGGTTAAAAAAAATGAAAAGCTTACTTCCGGAATCCTCA
AAAGTTTTAGAATTATTTTGTGGTTGTGGTACGATTGGAATTGCACTCAGAGAGAAAATAACTTCTCTGTATGGAATCGA
ATCCCATGACAATAGTATCCAATATGCAATTGAAAATGCGAAACGGAATGGAACAAATTCCTATCAATACGTGACGAAGG
ACTTGTACAAAGGTTATCTTCCAAAAGAACTCAAACAATACGCAATTTGGATTGTCAATCCTCCACGCTCTGGATTATCC
AAAGGGATCATTGATTCCACAACCAAATTAAAACCCAAAATCATGATCTATTCAAGTTGTAATCCAAGCACATTACAACG
GGATTTACGTTTATTAGAAGCGGTGGGCTACCGAATGGACAGTATGAGTCTTTTTGATTTTTTTCCGAGGACCAATCATT
ATGAAGTACTCGTTCGGCTAAAAAGAGGATAA

Upstream 100 bases:

>100_bases
CGCTGCTTTAGACCACTCAGCCACTTCTCCAAGAGTACCTATCCGTTATGTTAAATGCGAGTGCAGTGTCAATTGAATAT
TCATTGAATGGTCTAAGTGG

Downstream 100 bases:

>100_bases
ACAAAACAACTCACTTTTGTTGGAGTGAGTTGTGGTTCTGTTTTTACAAAAGTGAAATCATCACCTTTATTTCTCTTTTG
TGGATATTTTGAATGGTAAG

Product: TrmA family RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MEKLQIKLEKWVNGGYCLAHHDGHAVFIEGGLPGELVDITLTKQGKKEWFGVVTSVLEPSKFRIPSDCPVYLECGGCSYR
HLPYEEELKLKTNLLESMFPKWKGKTDVIFGPMEGYRNNVQWQVVGNEIGFFEKNTHQIVSKTSTLCKNVDKRLLVEDSK
TFLTQNTKHQKNHTNHNQKFGRSISLRLSKEKIVQYDLEETEIEVLGTQLKVPAKGFFQINQFLLETWLKKMKSLLPESS
KVLELFCGCGTIGIALREKITSLYGIESHDNSIQYAIENAKRNGTNSYQYVTKDLYKGYLPKELKQYAIWIVNPPRSGLS
KGIIDSTTKLKPKIMIYSSCNPSTLQRDLRLLEAVGYRMDSMSLFDFFPRTNHYEVLVRLKRG

Sequences:

>Translated_383_residues
MEKLQIKLEKWVNGGYCLAHHDGHAVFIEGGLPGELVDITLTKQGKKEWFGVVTSVLEPSKFRIPSDCPVYLECGGCSYR
HLPYEEELKLKTNLLESMFPKWKGKTDVIFGPMEGYRNNVQWQVVGNEIGFFEKNTHQIVSKTSTLCKNVDKRLLVEDSK
TFLTQNTKHQKNHTNHNQKFGRSISLRLSKEKIVQYDLEETEIEVLGTQLKVPAKGFFQINQFLLETWLKKMKSLLPESS
KVLELFCGCGTIGIALREKITSLYGIESHDNSIQYAIENAKRNGTNSYQYVTKDLYKGYLPKELKQYAIWIVNPPRSGLS
KGIIDSTTKLKPKIMIYSSCNPSTLQRDLRLLEAVGYRMDSMSLFDFFPRTNHYEVLVRLKRG
>Mature_383_residues
MEKLQIKLEKWVNGGYCLAHHDGHAVFIEGGLPGELVDITLTKQGKKEWFGVVTSVLEPSKFRIPSDCPVYLECGGCSYR
HLPYEEELKLKTNLLESMFPKWKGKTDVIFGPMEGYRNNVQWQVVGNEIGFFEKNTHQIVSKTSTLCKNVDKRLLVEDSK
TFLTQNTKHQKNHTNHNQKFGRSISLRLSKEKIVQYDLEETEIEVLGTQLKVPAKGFFQINQFLLETWLKKMKSLLPESS
KVLELFCGCGTIGIALREKITSLYGIESHDNSIQYAIENAKRNGTNSYQYVTKDLYKGYLPKELKQYAIWIVNPPRSGLS
KGIIDSTTKLKPKIMIYSSCNPSTLQRDLRLLEAVGYRMDSMSLFDFFPRTNHYEVLVRLKRG

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=193, Percent_Identity=26.4248704663212, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI51173878, Length=193, Percent_Identity=26.4248704663212, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1789148, Length=410, Percent_Identity=24.390243902439, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787083, Length=142, Percent_Identity=35.9154929577465, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 43977; Mature: 43977

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLQIKLEKWVNGGYCLAHHDGHAVFIEGGLPGELVDITLTKQGKKEWFGVVTSVLEPS
CCCCEEEHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHCCCC
KFRIPSDCPVYLECGGCSYRHLPYEEELKLKTNLLESMFPKWKGKTDVIFGPMEGYRNNV
CCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHCCCC
QWQVVGNEIGFFEKNTHQIVSKTSTLCKNVDKRLLVEDSKTFLTQNTKHQKNHTNHNQKF
EEEEECCCCCCEECCHHHHHHHHHHHHHCCCHHEEEECCHHHHHCCCCCCCCCCCCCHHH
GRSISLRLSKEKIVQYDLEETEIEVLGTQLKVPAKGFFQINQFLLETWLKKMKSLLPESS
CCEEEEEECHHHHHEECCCHHEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCH
KVLELFCGCGTIGIALREKITSLYGIESHDNSIQYAIENAKRNGTNSYQYVTKDLYKGYL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHCCCC
PKELKQYAIWIVNPPRSGLSKGIIDSTTKLKPKIMIYSSCNPSTLQRDLRLLEAVGYRMD
CHHHHCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCC
SMSLFDFFPRTNHYEVLVRLKRG
CCHHHHHCCCCCCEEEEEEEECC
>Mature Secondary Structure
MEKLQIKLEKWVNGGYCLAHHDGHAVFIEGGLPGELVDITLTKQGKKEWFGVVTSVLEPS
CCCCEEEHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHCCCC
KFRIPSDCPVYLECGGCSYRHLPYEEELKLKTNLLESMFPKWKGKTDVIFGPMEGYRNNV
CCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHCCCC
QWQVVGNEIGFFEKNTHQIVSKTSTLCKNVDKRLLVEDSKTFLTQNTKHQKNHTNHNQKF
EEEEECCCCCCEECCHHHHHHHHHHHHHCCCHHEEEECCHHHHHCCCCCCCCCCCCCHHH
GRSISLRLSKEKIVQYDLEETEIEVLGTQLKVPAKGFFQINQFLLETWLKKMKSLLPESS
CCEEEEEECHHHHHEECCCHHEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCH
KVLELFCGCGTIGIALREKITSLYGIESHDNSIQYAIENAKRNGTNSYQYVTKDLYKGYL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHCCCC
PKELKQYAIWIVNPPRSGLSKGIIDSTTKLKPKIMIYSSCNPSTLQRDLRLLEAVGYRMD
CHHHHCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCC
SMSLFDFFPRTNHYEVLVRLKRG
CCHHHHHCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA