| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is hppA [H]
Identifier: 183222788
GI number: 183222788
Start: 3566754
End: 3568901
Strand: Reverse
Name: hppA [H]
Synonym: LEPBI_I3448
Alternate gene names: 183222788
Gene position: 3568901-3566754 (Counterclockwise)
Preceding gene: 183222790
Following gene: 183222779
Centisome position: 99.15
GC content: 44.88
Gene sequence:
>2148_bases ATGAATGTAGAGTTAATCATTATCGTCATGGCGCTTGTCTCCATAGCCACGGCGATTTTCTACGCCGCGAGGGTAATACG TATCCAAGTGGGCGTAGATGGTGGCAATCAAAAAGAAACCGCCAAATTAAAAGAAATCTCCGCCGCGATCGCAGAAGGGG CAATGGCCTTCCTTCTCAGAGAATACCGAGTCATTCTGCTTTTTATCAGCTTCATGACAGTTCTCATTTACCTTCTATTA GATAACCCCAATACAGAATTCAATGAAGGCATTTATACTTCGATCGCTTTTGTATCAGGAGCCCTCATTTCCTGCCTTTC TGGCTTTATTGGAATGAAGATTGCGACCGCAGGAAACGTGAGAACAGCCCAAGCGGCAAAAACTTCCCTTTCCAAAGCGT TCCGAGTGGCATTCGACTCGGGAGCGGTGATGGGATTTGGTCTCATCGGTCTTGCCGTTTTAGGTATGATTGGTCTTTTC CTACTTTTCACAGGTGCCAATCCGACAGTTGCCAAACACATCCTGATGGAATCCCTTGCCGGTTTTGGTCTTGGTGGATC TTCGGTTGCCCTCTTTGGTCGTGTGGGTGGCGGAATTTATACGAAAGCCGCTGACGTAGGTGCTGACCTTGTTGGAAAAG TGGAAAAAGGAATCCCAGAAGATGACCCTCGTAACCCTGCAACCATCGCGGATAACGTGGGAGACAACGTAGGTGATATC GCGGGTATGGGTGCTGACCTTTTTGGTTCTGCTGCGGAAGCCACTTGTGCGGCCCTTGTGATTGGTGCCACAGCATCTGC ACTTGCGGACAATAACTCTGCACTTTTATACCCACTTTTGATCTCTGCGATTGGGATCCCAGCGTCTCTCATCACAACTT TTTTTGCACGAGTGAAAGAAGGTGGAAACGTAGAAAAAGCATTAAAACTACAACTTTGGATCTCTACTTTCATCGTTGCG GGTGCATTGTATTTTGCAACTGACATCTTCATGATCGATAGTTTTCAAATCGGCGACAAAACCATCACAAAATGGAATGT ATACACTTCAGTCGCATTAGGTTTGTTTGCTGGTATGTTCATTGGTTGGATCACAGAAATTTATACTTCCCACTCGTACA AACCAGTGCGTGAAGTAGCAGATGCATGTGAAACAGGCGCGGCAACAAACATCATTTATGGTTTGGCGCTTGGTTATAAG TCCACTGTTGTTCCTGTCATTTTACTTGTGATTGTCATTGTTGTTTCTAATATCCTTGCTGGTATGTATGGAATCGCCAT TGCAGCCATTGGTATGATTTCTACTATCGCGATTGGTCTTACCATTGATGCATATGGTCCAGTGTCTGACAACGCCGGTG GAATCGCTGAGATGGCAGAACTTGGAAAAGAAGTGCGTGATCGAACTGATACTTTAGATGCAGCAGGAAACACCACTGCC GCTGTTGGTAAAGGATTTGCAATTGGATCTGCGGCTCTCACTTCCCTTGCACTTTTTGCTGCCTTTATCACAAGAACACA AAATGCTTCCAAAGAAATGGGTGAAGGTGCGATTGATTTAACTTCTATCGAACTTCTCGATCCATTGGTTTTTGGTGGTT TACTGTTTGGAGCAATGCTTCCTTTTATTTTCTCTGCGATGACGATGAAGTCTGTTGGGAAAGCAGCTCTTGATATGGTA AAAGAAGTTCGTCGCCAATTCAAAGAGATCCCTGGTCTTATGGAAGGAACAGCAAAACCTGAGTATGCAAAATGTGTGGA TATTTCCACTTCTGCGGCTCTCCGTGAAATGATCCCTCCAGGTCTCCTTGTTCTCCTTAGCCCTATCGTTGTGGGTTATT TATTTGGAGTGAAGTCTCTTGCCGGCCTACTTGCAGGTGCACTTGTTTCTGGTGTGGTGCTTGCGATCTCTTCTGCCAAC TCTGGTGGAGCTTGGGACAACGCTAAAAAATACATCGAAAAAACTGCTGGTGGAAAAGGTTCTGAAAAACACAAAGCAGC AGTGGTTGGTGATACAGTTGGTGATCCGTTCAAAGATACATCAGGACCTGCGATCAACATTCTCATCAAACTAATGGCTA TCACATCACTCGTGTTTGCTGAGTTTTTTGTCACAAAAGGTGGAATTGTTTTAAACTTCTTCAAATAA
Upstream 100 bases:
>100_bases TTGCCATATTCTCCTAGACCGAAGTATCATCTATGGATTCTCATCGGTCATCTTCTAAAATATCTTAGAAATACAAATAA ACAATCTCAAAGAGGATCTC
Downstream 100 bases:
>100_bases GAATTTAAATTACAATCCAACGATTTGGTTCCATCATGATTGAAAGAACCAATTCAAACCTATGGATTCATTTAGATCCA TAGGAATGTTTGAGAAGCCG
Product: membrane-bound proton-translocating pyrophosphatase
Products: NA
Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]
Number of amino acids: Translated: 715; Mature: 715
Protein sequence:
>715_residues MNVELIIIVMALVSIATAIFYAARVIRIQVGVDGGNQKETAKLKEISAAIAEGAMAFLLREYRVILLFISFMTVLIYLLL DNPNTEFNEGIYTSIAFVSGALISCLSGFIGMKIATAGNVRTAQAAKTSLSKAFRVAFDSGAVMGFGLIGLAVLGMIGLF LLFTGANPTVAKHILMESLAGFGLGGSSVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGDI AGMGADLFGSAAEATCAALVIGATASALADNNSALLYPLLISAIGIPASLITTFFARVKEGGNVEKALKLQLWISTFIVA GALYFATDIFMIDSFQIGDKTITKWNVYTSVALGLFAGMFIGWITEIYTSHSYKPVREVADACETGAATNIIYGLALGYK STVVPVILLVIVIVVSNILAGMYGIAIAAIGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTTA AVGKGFAIGSAALTSLALFAAFITRTQNASKEMGEGAIDLTSIELLDPLVFGGLLFGAMLPFIFSAMTMKSVGKAALDMV KEVRRQFKEIPGLMEGTAKPEYAKCVDISTSAALREMIPPGLLVLLSPIVVGYLFGVKSLAGLLAGALVSGVVLAISSAN SGGAWDNAKKYIEKTAGGKGSEKHKAAVVGDTVGDPFKDTSGPAINILIKLMAITSLVFAEFFVTKGGIVLNFFK
Sequences:
>Translated_715_residues MNVELIIIVMALVSIATAIFYAARVIRIQVGVDGGNQKETAKLKEISAAIAEGAMAFLLREYRVILLFISFMTVLIYLLL DNPNTEFNEGIYTSIAFVSGALISCLSGFIGMKIATAGNVRTAQAAKTSLSKAFRVAFDSGAVMGFGLIGLAVLGMIGLF LLFTGANPTVAKHILMESLAGFGLGGSSVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGDI AGMGADLFGSAAEATCAALVIGATASALADNNSALLYPLLISAIGIPASLITTFFARVKEGGNVEKALKLQLWISTFIVA GALYFATDIFMIDSFQIGDKTITKWNVYTSVALGLFAGMFIGWITEIYTSHSYKPVREVADACETGAATNIIYGLALGYK STVVPVILLVIVIVVSNILAGMYGIAIAAIGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTTA AVGKGFAIGSAALTSLALFAAFITRTQNASKEMGEGAIDLTSIELLDPLVFGGLLFGAMLPFIFSAMTMKSVGKAALDMV KEVRRQFKEIPGLMEGTAKPEYAKCVDISTSAALREMIPPGLLVLLSPIVVGYLFGVKSLAGLLAGALVSGVVLAISSAN SGGAWDNAKKYIEKTAGGKGSEKHKAAVVGDTVGDPFKDTSGPAINILIKLMAITSLVFAEFFVTKGGIVLNFFK >Mature_715_residues MNVELIIIVMALVSIATAIFYAARVIRIQVGVDGGNQKETAKLKEISAAIAEGAMAFLLREYRVILLFISFMTVLIYLLL DNPNTEFNEGIYTSIAFVSGALISCLSGFIGMKIATAGNVRTAQAAKTSLSKAFRVAFDSGAVMGFGLIGLAVLGMIGLF LLFTGANPTVAKHILMESLAGFGLGGSSVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGDI AGMGADLFGSAAEATCAALVIGATASALADNNSALLYPLLISAIGIPASLITTFFARVKEGGNVEKALKLQLWISTFIVA GALYFATDIFMIDSFQIGDKTITKWNVYTSVALGLFAGMFIGWITEIYTSHSYKPVREVADACETGAATNIIYGLALGYK STVVPVILLVIVIVVSNILAGMYGIAIAAIGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTTA AVGKGFAIGSAALTSLALFAAFITRTQNASKEMGEGAIDLTSIELLDPLVFGGLLFGAMLPFIFSAMTMKSVGKAALDMV KEVRRQFKEIPGLMEGTAKPEYAKCVDISTSAALREMIPPGLLVLLSPIVVGYLFGVKSLAGLLAGALVSGVVLAISSAN SGGAWDNAKKYIEKTAGGKGSEKHKAAVVGDTVGDPFKDTSGPAINILIKLMAITSLVFAEFFVTKGGIVLNFFK
Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]
COG id: COG3808
COG function: function code C; Inorganic pyrophosphatase
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004131 [H]
Pfam domain/function: PF03030 H_PPase [H]
EC number: =3.6.1.1 [H]
Molecular weight: Translated: 74260; Mature: 74260
Theoretical pI: Translated: 5.26; Mature: 5.26
Prosite motif: PS00012 PHOSPHOPANTETHEINE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNVELIIIVMALVSIATAIFYAARVIRIQVGVDGGNQKETAKLKEISAAIAEGAMAFLLR CCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH EYRVILLFISFMTVLIYLLLDNPNTEFNEGIYTSIAFVSGALISCLSGFIGMKIATAGNV HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCC RTAQAAKTSLSKAFRVAFDSGAVMGFGLIGLAVLGMIGLFLLFTGANPTVAKHILMESLA CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH GFGLGGSSVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGDI CCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHH AGMGADLFGSAAEATCAALVIGATASALADNNSALLYPLLISAIGIPASLITTFFARVKE HCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHC GGNVEKALKLQLWISTFIVAGALYFATDIFMIDSFQIGDKTITKWNVYTSVALGLFAGMF CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECEECCCCCEEEHHHHHHHHHHHHHHHH IGWITEIYTSHSYKPVREVADACETGAATNIIYGLALGYKSTVVPVILLVIVIVVSNILA HHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH GMYGIAIAAIGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTTA HHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH AVGKGFAIGSAALTSLALFAAFITRTQNASKEMGEGAIDLTSIELLDPLVFGGLLFGAML HHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH PFIFSAMTMKSVGKAALDMVKEVRRQFKEIPGLMEGTAKPEYAKCVDISTSAALREMIPP HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHCCCCHHHHHHHHCCC GLLVLLSPIVVGYLFGVKSLAGLLAGALVSGVVLAISSANSGGAWDNAKKYIEKTAGGKG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHCCCCC SEKHKAAVVGDTVGDPFKDTSGPAINILIKLMAITSLVFAEFFVTKGGIVLNFFK CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC >Mature Secondary Structure MNVELIIIVMALVSIATAIFYAARVIRIQVGVDGGNQKETAKLKEISAAIAEGAMAFLLR CCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH EYRVILLFISFMTVLIYLLLDNPNTEFNEGIYTSIAFVSGALISCLSGFIGMKIATAGNV HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCC RTAQAAKTSLSKAFRVAFDSGAVMGFGLIGLAVLGMIGLFLLFTGANPTVAKHILMESLA CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH GFGLGGSSVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGDI CCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHH AGMGADLFGSAAEATCAALVIGATASALADNNSALLYPLLISAIGIPASLITTFFARVKE HCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHC GGNVEKALKLQLWISTFIVAGALYFATDIFMIDSFQIGDKTITKWNVYTSVALGLFAGMF CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECEECCCCCEEEHHHHHHHHHHHHHHHH IGWITEIYTSHSYKPVREVADACETGAATNIIYGLALGYKSTVVPVILLVIVIVVSNILA HHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH GMYGIAIAAIGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTTA HHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH AVGKGFAIGSAALTSLALFAAFITRTQNASKEMGEGAIDLTSIELLDPLVFGGLLFGAML HHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH PFIFSAMTMKSVGKAALDMVKEVRRQFKEIPGLMEGTAKPEYAKCVDISTSAALREMIPP HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHCCCCHHHHHHHHCCC GLLVLLSPIVVGYLFGVKSLAGLLAGALVSGVVLAISSANSGGAWDNAKKYIEKTAGGKG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHCCCCC SEKHKAAVVGDTVGDPFKDTSGPAINILIKLMAITSLVFAEFFVTKGGIVLNFFK CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA