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The map label for this gene is dltE [H]

Identifier: 183222664

GI number: 183222664

Start: 3432058

End: 3432810

Strand: Reverse

Name: dltE [H]

Synonym: LEPBI_I3319

Alternate gene names: 183222664

Gene position: 3432810-3432058 (Counterclockwise)

Preceding gene: 183222666

Following gene: 183222662

Centisome position: 95.36

GC content: 41.04

Gene sequence:

>753_bases
TTGATGTTATTGAAAGGAAATACAATCCTCATCACCGGTGGAACGAGTGGGATCGGCTTCGCTCTCGCAAAAAGATTCTC
TGATCTTGGAAACCAAATATTGGTTTGTGGTACGAATGAAAAGAAATTGGAAGAGATTTCTATATCTTATCCCAGCTGGG
CTACGTATCGATTTGATATCTCTCTACCAGAAGAGAGGGTGAAATTGTTTCAAAAAACCACAGAAGATTTTCCAGAACTC
AATGTAGTATTCAATAATGCGGGGATCCAAAGGTATCCGAAATTGAGTGAAGTAGAACCTTGGACAGATTTAGAAAAGGA
GATCGATGTAAATTTGGGAGCTCCCATCCATCTTTCGATGTTATTCGCCAAGCACCTGTTCGCAAAAAAAAATGCGGCGA
TTTTAAATACAACCTCTGGATTGTCGCACATCCCGTTGGCGTATGCACCTATTTATAGTGCGACCAAAGCCGCTTTACAC
TCGTTCACACTCACACTACGATTTCAATTTCGAAATCAACCCATTGAAGTCATTGAAGTTTCGCCACCAATGGTGGATAC
AGACTTAGGAATCCCTAACACACATACGGCGAGTCTGAATTTGGACGAATATGCGGATACCGTTATGATTGGATTACAAA
ACGGAGAACTGGAAATCACAACTGGATATTCTACAATCACAGCCAATGCCAGTCGGGAACAAAAGAATGAGATCTTTTTG
TCAATGAACTTGGCTCGTAGTTCCTCAAACTAA

Upstream 100 bases:

>100_bases
TCAAATTACAAAATGAAAAAAATGTTAGTTTTGAAACTTACAGACTTGACATTTTGTAACTTACAAAATATTGTAAATGT
AAGTAAGGAAAAGGTACAAA

Downstream 100 bases:

>100_bases
GGACCGACCGACAAAGGCACACGCGATGGCATCCCAGGAGTCATCGTGGCCTTTTAGGTCCTTAAATCCCAAAATCATTT
GGATCGCCGCCCGGACTTCC

Product: SDR family dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MMLLKGNTILITGGTSGIGFALAKRFSDLGNQILVCGTNEKKLEEISISYPSWATYRFDISLPEERVKLFQKTTEDFPEL
NVVFNNAGIQRYPKLSEVEPWTDLEKEIDVNLGAPIHLSMLFAKHLFAKKNAAILNTTSGLSHIPLAYAPIYSATKAALH
SFTLTLRFQFRNQPIEVIEVSPPMVDTDLGIPNTHTASLNLDEYADTVMIGLQNGELEITTGYSTITANASREQKNEIFL
SMNLARSSSN

Sequences:

>Translated_250_residues
MMLLKGNTILITGGTSGIGFALAKRFSDLGNQILVCGTNEKKLEEISISYPSWATYRFDISLPEERVKLFQKTTEDFPEL
NVVFNNAGIQRYPKLSEVEPWTDLEKEIDVNLGAPIHLSMLFAKHLFAKKNAAILNTTSGLSHIPLAYAPIYSATKAALH
SFTLTLRFQFRNQPIEVIEVSPPMVDTDLGIPNTHTASLNLDEYADTVMIGLQNGELEITTGYSTITANASREQKNEIFL
SMNLARSSSN
>Mature_250_residues
MMLLKGNTILITGGTSGIGFALAKRFSDLGNQILVCGTNEKKLEEISISYPSWATYRFDISLPEERVKLFQKTTEDFPEL
NVVFNNAGIQRYPKLSEVEPWTDLEKEIDVNLGAPIHLSMLFAKHLFAKKNAAILNTTSGLSHIPLAYAPIYSATKAALH
SFTLTLRFQFRNQPIEVIEVSPPMVDTDLGIPNTHTASLNLDEYADTVMIGLQNGELEITTGYSTITANASREQKNEIFL
SMNLARSSSN

Specific function: Unknown

COG id: COG3967

COG function: function code M; Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=24.8756218905473, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI87082160, Length=189, Percent_Identity=30.6878306878307, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=26.5625, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786812, Length=188, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790717, Length=198, Percent_Identity=26.2626262626263, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=21.9101123595506, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=206, Percent_Identity=26.6990291262136, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=213, Percent_Identity=26.2910798122066, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=194, Percent_Identity=29.3814432989691, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=193, Percent_Identity=25.3886010362694, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=199, Percent_Identity=23.6180904522613, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=26.3959390862944, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=186, Percent_Identity=26.3440860215054, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580925, Length=201, Percent_Identity=25.3731343283582, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=26.8041237113402, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=27.1794871794872, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643142, Length=193, Percent_Identity=29.0155440414508, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24649181, Length=234, Percent_Identity=26.0683760683761, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27703; Mature: 27703

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLLKGNTILITGGTSGIGFALAKRFSDLGNQILVCGTNEKKLEEISISYPSWATYRFDI
CEEEECCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCEEEEEEEE
SLPEERVKLFQKTTEDFPELNVVFNNAGIQRYPKLSEVEPWTDLEKEIDVNLGAPIHLSM
CCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHH
LFAKHLFAKKNAAILNTTSGLSHIPLAYAPIYSATKAALHSFTLTLRFQFRNQPIEVIEV
HHHHHHHHCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHEEEEEEEEEEECCCCEEEEEC
SPPMVDTDLGIPNTHTASLNLDEYADTVMIGLQNGELEITTGYSTITANASREQKNEIFL
CCCEEECCCCCCCCEEEEEEHHHCCCEEEEEEECCEEEEEECCEEEEECCCCCCCCEEEE
SMNLARSSSN
EEEECCCCCC
>Mature Secondary Structure
MMLLKGNTILITGGTSGIGFALAKRFSDLGNQILVCGTNEKKLEEISISYPSWATYRFDI
CEEEECCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCEEEEEEEE
SLPEERVKLFQKTTEDFPELNVVFNNAGIQRYPKLSEVEPWTDLEKEIDVNLGAPIHLSM
CCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHH
LFAKHLFAKKNAAILNTTSGLSHIPLAYAPIYSATKAALHSFTLTLRFQFRNQPIEVIEV
HHHHHHHHCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHEEEEEEEEEEECCCCEEEEEC
SPPMVDTDLGIPNTHTASLNLDEYADTVMIGLQNGELEITTGYSTITANASREQKNEIFL
CCCEEECCCCCCCCEEEEEEHHHCCCEEEEEEECCEEEEEECCEEEEECCCCCCCCEEEE
SMNLARSSSN
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 7797557 [H]