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The map label for this gene is prcA [H]

Identifier: 183222626

GI number: 183222626

Start: 3392613

End: 3394304

Strand: Reverse

Name: prcA [H]

Synonym: LEPBI_I3281

Alternate gene names: 183222626

Gene position: 3394304-3392613 (Counterclockwise)

Preceding gene: 183222627

Following gene: 183222625

Centisome position: 94.29

GC content: 42.85

Gene sequence:

>1692_bases
ATGAAATTTCTGCAATTAGGGTTGATCACAATCATCATCACTAGCTTGGGTTTGGGGAATTGTAATCCTATCAAAAAAAG
TGATCCATTCAGCGACAATTTACTCTTACTTTTGCTTTTAAATTCATTTGCCACTGCTAGAGAATTGGATTGCACGTTTT
CTTCTTCTGGAACTGATTCACTTTATGATGACCAATGGCATCTACAAAACTACGGCCAATTAGGCGGTACCACCGGGGAA
GACGCACGAGTCAAACCTGTCTGGGACCAAGGTTATTCGGGAAATCAAGTCATTGTGAGTGTGGTGGACGATGGTCTAGA
CATACGTCACGAAGATTTAGCTGCAAATATTTCAATTTCCACACGTGGTCTCAATTTATTCAATAACACATTCAATCCCT
CCCATTCATATACCAACAGTTTCCATGGATCTGCCGTTGGCGGTGTCATAGGTGCTACTGGTGGAAATGGAATGGGTGTT
AGAGGAGCTGCACCTTGTTCCAAACTTGTTGGAGTGAATATCTTAGAAAAATCGACAATCTTTACTTCGGATGAATATAG
AGCAATGGTCAATGAGTCTGGAAGAGTATTTATTTCCAATAATAGTTGGGGATCTCCGGATTTATACGGTTGGTTATGGC
CGTCCAGTAGTCTTTGGCAACAAGGGATCAACGAAGGGGTCAGTTTAGGCAGAGGTGGAAAAGGAACTGTATATTTTTGG
GCAGCAGGCAATGGAGCCAATGGTGGAACAGTCGCATCACCTACATTAGTTGACAATGCCAATTTTGATGGGCAAGCGAA
TTATTATGGTGTCATGGCCATTGGTGGGATAGGACAAAATGGAATGAAGGCTTCGTATTCCGAGTCTGGTGCCAACCTCT
GGGTCGTAGCCCATACACAAGGAAACAATGCCTCGGCTTATACCACAGCCATATCCACAACGGATGCCTCGGGCGGATTT
GGCTTCAATGCAGGTGGAACCGGTGGAGATTATGTTTTTTCTAATTATACACGTAGATTTAATGGCACATCCTCCGCGAC
TCCACTTGCTGCTGGTGTTGCCGCCTTACTCTTAAGTAAGTATCCGGAATTCACTTGGAGAGACGTACGAGAGTTAATTG
CTTATTCTGCCAGACAAAATGATGCTTTTGATTCAGATTGGACAACAAACGCTGCTGGCCTAAAGATCAATCATAAATAT
GGTTTCGGAGCAATTGACGCAGAACAACTTTTTGTTCGAGCCAATACTTGGACTCCGATTTCAGCCAGTTTCAAAACAGA
AGCGATGAATACTGTTTCGCCAGGCACTTCCATACCTGACAATGATCTAGTAACAGGTGCCAATGTATCCTATCCTGTCA
CATCTTCCATTACTTATGTTGAGTTTGTGGATGTTGAATTCACTTCGAATCATACTTATTTTCCGGAATTAAGGATCACA
GTAACTTCACCAAGCGGAACCGTAAGTGTATTAACGGAACTTCATGCCTGTCGTAATCCTTTAAATAATTCCGGTTGTAC
ATCAGGGAATACTTCCATTGCAACGATGACTGGTTCTTCTACATATCGATTTGGATTGACACGATTACTCGGGGAAAATC
CAAACGGAAGTTGGAACATTCGAGTTTACGATGGGGGCGTTGGTGATACCGGATCCATCCAATCCATTCGACTACGAATT
TATGGAAGGTAA

Upstream 100 bases:

>100_bases
TTAGCAGAAGCCAAGGCTTAAAAAAAAACAAAATTTACCAAAGGAATTCGATTGAATCAACTGATTTGATTGTTATTCCT
TTTAGTAGGATGAAGACCTC

Downstream 100 bases:

>100_bases
TAAAATGAAGAGACCAACTTTTTTGCAGACACAAGAGATTCGAAATTGTTTCATTCAGATTTTTCACATTCTTATATTAG
CAGTTATAATTCTATGTTTC

Product: putative subtilisin-like serine protease

Products: NA

Alternate protein names: Trypsin [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MKFLQLGLITIIITSLGLGNCNPIKKSDPFSDNLLLLLLLNSFATARELDCTFSSSGTDSLYDDQWHLQNYGQLGGTTGE
DARVKPVWDQGYSGNQVIVSVVDDGLDIRHEDLAANISISTRGLNLFNNTFNPSHSYTNSFHGSAVGGVIGATGGNGMGV
RGAAPCSKLVGVNILEKSTIFTSDEYRAMVNESGRVFISNNSWGSPDLYGWLWPSSSLWQQGINEGVSLGRGGKGTVYFW
AAGNGANGGTVASPTLVDNANFDGQANYYGVMAIGGIGQNGMKASYSESGANLWVVAHTQGNNASAYTTAISTTDASGGF
GFNAGGTGGDYVFSNYTRRFNGTSSATPLAAGVAALLLSKYPEFTWRDVRELIAYSARQNDAFDSDWTTNAAGLKINHKY
GFGAIDAEQLFVRANTWTPISASFKTEAMNTVSPGTSIPDNDLVTGANVSYPVTSSITYVEFVDVEFTSNHTYFPELRIT
VTSPSGTVSVLTELHACRNPLNNSGCTSGNTSIATMTGSSTYRFGLTRLLGENPNGSWNIRVYDGGVGDTGSIQSIRLRI
YGR

Sequences:

>Translated_563_residues
MKFLQLGLITIIITSLGLGNCNPIKKSDPFSDNLLLLLLLNSFATARELDCTFSSSGTDSLYDDQWHLQNYGQLGGTTGE
DARVKPVWDQGYSGNQVIVSVVDDGLDIRHEDLAANISISTRGLNLFNNTFNPSHSYTNSFHGSAVGGVIGATGGNGMGV
RGAAPCSKLVGVNILEKSTIFTSDEYRAMVNESGRVFISNNSWGSPDLYGWLWPSSSLWQQGINEGVSLGRGGKGTVYFW
AAGNGANGGTVASPTLVDNANFDGQANYYGVMAIGGIGQNGMKASYSESGANLWVVAHTQGNNASAYTTAISTTDASGGF
GFNAGGTGGDYVFSNYTRRFNGTSSATPLAAGVAALLLSKYPEFTWRDVRELIAYSARQNDAFDSDWTTNAAGLKINHKY
GFGAIDAEQLFVRANTWTPISASFKTEAMNTVSPGTSIPDNDLVTGANVSYPVTSSITYVEFVDVEFTSNHTYFPELRIT
VTSPSGTVSVLTELHACRNPLNNSGCTSGNTSIATMTGSSTYRFGLTRLLGENPNGSWNIRVYDGGVGDTGSIQSIRLRI
YGR
>Mature_563_residues
MKFLQLGLITIIITSLGLGNCNPIKKSDPFSDNLLLLLLLNSFATARELDCTFSSSGTDSLYDDQWHLQNYGQLGGTTGE
DARVKPVWDQGYSGNQVIVSVVDDGLDIRHEDLAANISISTRGLNLFNNTFNPSHSYTNSFHGSAVGGVIGATGGNGMGV
RGAAPCSKLVGVNILEKSTIFTSDEYRAMVNESGRVFISNNSWGSPDLYGWLWPSSSLWQQGINEGVSLGRGGKGTVYFW
AAGNGANGGTVASPTLVDNANFDGQANYYGVMAIGGIGQNGMKASYSESGANLWVVAHTQGNNASAYTTAISTTDASGGF
GFNAGGTGGDYVFSNYTRRFNGTSSATPLAAGVAALLLSKYPEFTWRDVRELIAYSARQNDAFDSDWTTNAAGLKINHKY
GFGAIDAEQLFVRANTWTPISASFKTEAMNTVSPGTSIPDNDLVTGANVSYPVTSSITYVEFVDVEFTSNHTYFPELRIT
VTSPSGTVSVLTELHACRNPLNNSGCTSGNTSIATMTGSSTYRFGLTRLLGENPNGSWNIRVYDGGVGDTGSIQSIRLRI
YGR

Specific function: Degrades phycobiliproteins in vitro. Has a substrate specificity similar to that of trypsin [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI299523015, Length=511, Percent_Identity=27.7886497064579, Blast_Score=189, Evalue=8e-48,
Organism=Homo sapiens, GI20336244, Length=513, Percent_Identity=28.2651072124756, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI76443679, Length=510, Percent_Identity=29.0196078431373, Blast_Score=185, Evalue=8e-47,
Organism=Homo sapiens, GI20336246, Length=511, Percent_Identity=27.7886497064579, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI4505577, Length=493, Percent_Identity=28.3975659229209, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI20336180, Length=493, Percent_Identity=28.3975659229209, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI20336182, Length=493, Percent_Identity=28.6004056795132, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI20336188, Length=493, Percent_Identity=28.6004056795132, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI20336184, Length=493, Percent_Identity=28.6004056795132, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI27894285, Length=492, Percent_Identity=28.0487804878049, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI20336190, Length=493, Percent_Identity=28.6004056795132, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI4505579, Length=512, Percent_Identity=27.9296875, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI20336242, Length=520, Percent_Identity=27.3076923076923, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI295424143, Length=524, Percent_Identity=27.4809160305344, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI20336248, Length=518, Percent_Identity=28.7644787644788, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI20336186, Length=340, Percent_Identity=27.6470588235294, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI295424145, Length=263, Percent_Identity=28.5171102661597, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71987206, Length=545, Percent_Identity=26.7889908256881, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25141268, Length=518, Percent_Identity=27.027027027027, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71988308, Length=516, Percent_Identity=27.3255813953488, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71988312, Length=516, Percent_Identity=27.3255813953488, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI71988315, Length=516, Percent_Identity=27.3255813953488, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71988321, Length=516, Percent_Identity=27.3255813953488, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71988297, Length=516, Percent_Identity=27.3255813953488, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71988301, Length=516, Percent_Identity=27.3255813953488, Blast_Score=153, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71983555, Length=376, Percent_Identity=27.6595744680851, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71987215, Length=465, Percent_Identity=26.0215053763441, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17505240, Length=463, Percent_Identity=26.7818574514039, Blast_Score=121, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324091, Length=520, Percent_Identity=29.2307692307692, Blast_Score=166, Evalue=8e-42,
Organism=Drosophila melanogaster, GI17136192, Length=494, Percent_Identity=28.7449392712551, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24642494, Length=515, Percent_Identity=27.7669902912621, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24642490, Length=515, Percent_Identity=27.7669902912621, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI45555723, Length=515, Percent_Identity=27.7669902912621, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24642492, Length=515, Percent_Identity=27.7669902912621, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281360987, Length=515, Percent_Identity=27.7669902912621, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24642488, Length=515, Percent_Identity=27.7669902912621, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24642484, Length=515, Percent_Identity=27.7669902912621, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24642486, Length=515, Percent_Identity=27.7669902912621, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24650058, Length=515, Percent_Identity=26.0194174757282, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24650060, Length=515, Percent_Identity=26.0194174757282, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI45553513, Length=515, Percent_Identity=26.0194174757282, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI45553515, Length=515, Percent_Identity=26.0194174757282, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24650056, Length=515, Percent_Identity=26.0194174757282, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17864552, Length=515, Percent_Identity=26.0194174757282, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360985, Length=224, Percent_Identity=29.0178571428571, Blast_Score=86, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 59889; Mature: 59889

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLQLGLITIIITSLGLGNCNPIKKSDPFSDNLLLLLLLNSFATARELDCTFSSSGTDS
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHCCCCCEEEEEEECCCCCCC
LYDDQWHLQNYGQLGGTTGEDARVKPVWDQGYSGNQVIVSVVDDGLDIRHEDLAANISIS
CCCCCHHHCCHHHCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEE
TRGLNLFNNTFNPSHSYTNSFHGSAVGGVIGATGGNGMGVRGAAPCSKLVGVNILEKSTI
ECCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHCCEEEECCEE
FTSDEYRAMVNESGRVFISNNSWGSPDLYGWLWPSSSLWQQGINEGVSLGRGGKGTVYFW
EECHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEE
AAGNGANGGTVASPTLVDNANFDGQANYYGVMAIGGIGQNGMKASYSESGANLWVVAHTQ
ECCCCCCCCEECCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEC
GNNASAYTTAISTTDASGGFGFNAGGTGGDYVFSNYTRRFNGTSSATPLAAGVAALLLSK
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
YPEFTWRDVRELIAYSARQNDAFDSDWTTNAAGLKINHKYGFGAIDAEQLFVRANTWTPI
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHEEEEECCCCCC
SASFKTEAMNTVSPGTSIPDNDLVTGANVSYPVTSSITYVEFVDVEFTSNHTYFPELRIT
CCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEEEECCCCEECCEEEEE
VTSPSGTVSVLTELHACRNPLNNSGCTSGNTSIATMTGSSTYRFGLTRLLGENPNGSWNI
EECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEHHHHHHHHCCCCCCEEEE
RVYDGGVGDTGSIQSIRLRIYGR
EEEECCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKFLQLGLITIIITSLGLGNCNPIKKSDPFSDNLLLLLLLNSFATARELDCTFSSSGTDS
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHCCCCCEEEEEEECCCCCCC
LYDDQWHLQNYGQLGGTTGEDARVKPVWDQGYSGNQVIVSVVDDGLDIRHEDLAANISIS
CCCCCHHHCCHHHCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEE
TRGLNLFNNTFNPSHSYTNSFHGSAVGGVIGATGGNGMGVRGAAPCSKLVGVNILEKSTI
ECCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHCCEEEECCEE
FTSDEYRAMVNESGRVFISNNSWGSPDLYGWLWPSSSLWQQGINEGVSLGRGGKGTVYFW
EECHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEE
AAGNGANGGTVASPTLVDNANFDGQANYYGVMAIGGIGQNGMKASYSESGANLWVVAHTQ
ECCCCCCCCEECCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEC
GNNASAYTTAISTTDASGGFGFNAGGTGGDYVFSNYTRRFNGTSSATPLAAGVAALLLSK
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
YPEFTWRDVRELIAYSARQNDAFDSDWTTNAAGLKINHKYGFGAIDAEQLFVRANTWTPI
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHEEEEECCCCCC
SASFKTEAMNTVSPGTSIPDNDLVTGANVSYPVTSSITYVEFVDVEFTSNHTYFPELRIT
CCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEEEECCCCEECCEEEEE
VTSPSGTVSVLTELHACRNPLNNSGCTSGNTSIATMTGSSTYRFGLTRLLGENPNGSWNI
EECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEHHHHHHHHCCCCCCEEEE
RVYDGGVGDTGSIQSIRLRIYGR
EEEECCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1900347; 8944762 [H]