| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is rsbU [H]
Identifier: 183222358
GI number: 183222358
Start: 3124815
End: 3126740
Strand: Direct
Name: rsbU [H]
Synonym: LEPBI_I3011
Alternate gene names: 183222358
Gene position: 3124815-3126740 (Clockwise)
Preceding gene: 183222354
Following gene: 183222359
Centisome position: 86.81
GC content: 34.84
Gene sequence:
>1926_bases ATGAGAATTCTCTCATTTTTTTTCCCCATTTTTTTCTCTACGATCTTCTCCCTCGTAGCTGAACCTGTGTCCATCAGCGC AAACTCCGTCGTGACCCTATCTGAAAATTGGACATTTACGACAAATGGAGTCACAAATCCAATCCAAGTGGGGAAAGGAC TCTCCTTACAAGGGATCCTTCCACCTGTCGAAGGGTATTATGAAACTCAATTCATTTACAAACCGAGCAACAAACCTCTT GGTATTTATTTAGACCGTGTCCAAGAGGTTGATACCTTTATCGTCAATGGAATCAGACTCGGGCAAACTGGAAGCGTGAC AAATGATGGAACTTATTTGCCCAATTGGTATTACAAACGTCTCTACTACATTCCCAATCATGTATTAAAAGAAAATTCCA CCAACCAATTAAAAATTGAAATTCATTTTCGTAACAAAACTTTTCAAGGAGGGCTATTCCGCCGAGTTCCCATTATGGGA AATTATGACAAATTACATGAACAGATCTTAATTGAAGATGGTCGTGATTTCTGTTTTATCATGTTATTTTTTGGGATTGG GGCATATCAAATTTTCTCCATTCTCTTAAAAAGACAGGCGAAAACTAATTTTTATCTATTGTTGTCTACATTAATATTCG TTATGTGGAGATTACCTCTTTTAAACATAAGTTATACATACACTGATTTTACTTTTTTCTTTTGGTTAAAGGTTTTTTTC ACATCACAAACGTTACTACCAGTTTCTATATTTTTATTCAGCTACTCTCTTTTTCAAAACAAACTTTCCTTAAAAGAAAG ACTTTTGGTTTTATTTTTGATAACCATAGCATTTGTCCAAACTTGGAATATAGAACTCCCAACAAGAATTTTATTATTAC GAATTTGGGAATTTTCTCTCTTATTTATAGTATTTTTTATCTTAAGAGCTGTCATTAGAGCCGCGCGAGCAAAAAGAACG GAAGCTTACTTTTTATCAATTGGATTTATCTGTATCTGTTTCGGAGCAACTTTCGATATCATCATTGATGTGACATCTGG TAAAAATATTTACCTTACTCAATATGGATTTTTGATCTTAATGATTTTATCGGGAGTTGCGATCTCTTATCGAAATGCAA AAAACGAAACTGAACTTTCGATATTAACCAAAGATTTAGAAATTCGTGTCCGAGAGAGAACAATCGAACTCAGAGAAAAA AATCAAGATTTGGAACAGGACTTATTTTTTGCATCGCAGCTACAAAGTTACCTATTACCAAAAAATCATCCGAATACAAA AGGAATACGGATTCACACCACCTATCTACCAATGAGACAAGTTGGTGGTGATTTGTATGATTGGGTTGAGTTAGATGAAA ATCGATTGATCCTCTTGATTGCTGACGTTGCCGGACATGGTGTTCCTGCTGCTTTTGTTTCTTCAATGGTGAAAGTACAA TTTCGAGAATCAACCAAATCAATTCATTCACCGAAACTGATTTTAGAACACATGAACCAAGCACTCACTTCCCTCGTGAG TCGATATTTTATTACCGCCTGTTGCGCCTTAGTTGACACAAAAGAAAATACGATTATTTTTTCTACTGCAGGACACCCAA ACCCAATCATTTTCAACAAAATTCAGAAACGATTTGAATTTATGAAGATTAAGGGTCCGATCATTGGATGGAAAGAATCG TTCACATTTGTGGAATGGAAACACCAAATGCAAAAAGGCGATCGTTATTTCTTTTTTACTGATGGAGTTACGGAAGCTCG CGCGGAAAATAAATTGTTCGGCGAAGGCAAAATTCTTGATTTATTAGAGAAAGGTAAAGACAAAGACATCAAATCATTAT CCCAAGAAATTGTAGTTCAAATCACTAAGTATTCTGAAGCAGAATTAAAAGATGATGTTACATTTTTCTTTGTTGATATA ATTTAA
Upstream 100 bases:
>100_bases TAATTGTCATAAAATTTCCTTAAAAAACCGATCCTTAGGCAACTCGAATCTAAATTCAACTTGCAATCCCTTCCGACTTC ACTATCATTAGCGGATAGCG
Downstream 100 bases:
>100_bases GTTAGTATATGGAACCAACACCTTATTCAGTATTGATCATCGAAGATGAGTATCCTGCTCGTATGCTGATGATGGACTAT GTTTTGAATTGTCCTGAATT
Product: putative phosphoserine phosphatase
Products: NA
Alternate protein names: Sigma factor sigB regulation protein rsbU [H]
Number of amino acids: Translated: 641; Mature: 641
Protein sequence:
>641_residues MRILSFFFPIFFSTIFSLVAEPVSISANSVVTLSENWTFTTNGVTNPIQVGKGLSLQGILPPVEGYYETQFIYKPSNKPL GIYLDRVQEVDTFIVNGIRLGQTGSVTNDGTYLPNWYYKRLYYIPNHVLKENSTNQLKIEIHFRNKTFQGGLFRRVPIMG NYDKLHEQILIEDGRDFCFIMLFFGIGAYQIFSILLKRQAKTNFYLLLSTLIFVMWRLPLLNISYTYTDFTFFFWLKVFF TSQTLLPVSIFLFSYSLFQNKLSLKERLLVLFLITIAFVQTWNIELPTRILLLRIWEFSLLFIVFFILRAVIRAARAKRT EAYFLSIGFICICFGATFDIIIDVTSGKNIYLTQYGFLILMILSGVAISYRNAKNETELSILTKDLEIRVRERTIELREK NQDLEQDLFFASQLQSYLLPKNHPNTKGIRIHTTYLPMRQVGGDLYDWVELDENRLILLIADVAGHGVPAAFVSSMVKVQ FRESTKSIHSPKLILEHMNQALTSLVSRYFITACCALVDTKENTIIFSTAGHPNPIIFNKIQKRFEFMKIKGPIIGWKES FTFVEWKHQMQKGDRYFFFTDGVTEARAENKLFGEGKILDLLEKGKDKDIKSLSQEIVVQITKYSEAELKDDVTFFFVDI I
Sequences:
>Translated_641_residues MRILSFFFPIFFSTIFSLVAEPVSISANSVVTLSENWTFTTNGVTNPIQVGKGLSLQGILPPVEGYYETQFIYKPSNKPL GIYLDRVQEVDTFIVNGIRLGQTGSVTNDGTYLPNWYYKRLYYIPNHVLKENSTNQLKIEIHFRNKTFQGGLFRRVPIMG NYDKLHEQILIEDGRDFCFIMLFFGIGAYQIFSILLKRQAKTNFYLLLSTLIFVMWRLPLLNISYTYTDFTFFFWLKVFF TSQTLLPVSIFLFSYSLFQNKLSLKERLLVLFLITIAFVQTWNIELPTRILLLRIWEFSLLFIVFFILRAVIRAARAKRT EAYFLSIGFICICFGATFDIIIDVTSGKNIYLTQYGFLILMILSGVAISYRNAKNETELSILTKDLEIRVRERTIELREK NQDLEQDLFFASQLQSYLLPKNHPNTKGIRIHTTYLPMRQVGGDLYDWVELDENRLILLIADVAGHGVPAAFVSSMVKVQ FRESTKSIHSPKLILEHMNQALTSLVSRYFITACCALVDTKENTIIFSTAGHPNPIIFNKIQKRFEFMKIKGPIIGWKES FTFVEWKHQMQKGDRYFFFTDGVTEARAENKLFGEGKILDLLEKGKDKDIKSLSQEIVVQITKYSEAELKDDVTFFFVDI I >Mature_641_residues MRILSFFFPIFFSTIFSLVAEPVSISANSVVTLSENWTFTTNGVTNPIQVGKGLSLQGILPPVEGYYETQFIYKPSNKPL GIYLDRVQEVDTFIVNGIRLGQTGSVTNDGTYLPNWYYKRLYYIPNHVLKENSTNQLKIEIHFRNKTFQGGLFRRVPIMG NYDKLHEQILIEDGRDFCFIMLFFGIGAYQIFSILLKRQAKTNFYLLLSTLIFVMWRLPLLNISYTYTDFTFFFWLKVFF TSQTLLPVSIFLFSYSLFQNKLSLKERLLVLFLITIAFVQTWNIELPTRILLLRIWEFSLLFIVFFILRAVIRAARAKRT EAYFLSIGFICICFGATFDIIIDVTSGKNIYLTQYGFLILMILSGVAISYRNAKNETELSILTKDLEIRVRERTIELREK NQDLEQDLFFASQLQSYLLPKNHPNTKGIRIHTTYLPMRQVGGDLYDWVELDENRLILLIADVAGHGVPAAFVSSMVKVQ FRESTKSIHSPKLILEHMNQALTSLVSRYFITACCALVDTKENTIIFSTAGHPNPIIFNKIQKRFEFMKIKGPIIGWKES FTFVEWKHQMQKGDRYFFFTDGVTEARAENKLFGEGKILDLLEKGKDKDIKSLSQEIVVQITKYSEAELKDDVTFFFVDI I
Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]
COG id: COG2208
COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PP2C-like domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017944 - InterPro: IPR001932 - InterPro: IPR014787 - InterPro: IPR010822 - ProDom: PD685490 [H]
Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]
EC number: =3.1.3.3 [H]
Molecular weight: Translated: 74294; Mature: 74294
Theoretical pI: Translated: 9.23; Mature: 9.23
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRILSFFFPIFFSTIFSLVAEPVSISANSVVTLSENWTFTTNGVTNPIQVGKGLSLQGIL CHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCEEEEECCCCCHHHHCCCCCCCCCC PPVEGYYETQFIYKPSNKPLGIYLDRVQEVDTFIVNGIRLGQTGSVTNDGTYLPNWYYKR CCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHE LYYIPNHVLKENSTNQLKIEIHFRNKTFQGGLFRRVPIMGNYDKLHEQILIEDGRDFCFI EEECCCHHHCCCCCCEEEEEEEECCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCHHHH MLFFGIGAYQIFSILLKRQAKTNFYLLLSTLIFVMWRLPLLNISYTYTDFTFFFWLKVFF HHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHH TSQTLLPVSIFLFSYSLFQNKLSLKERLLVLFLITIAFVQTWNIELPTRILLLRIWEFSL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH LFIVFFILRAVIRAARAKRTEAYFLSIGFICICFGATFDIIIDVTSGKNIYLTQYGFLIL HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEHHHHHHH MILSGVAISYRNAKNETELSILTKDLEIRVRERTIELREKNQDLEQDLFFASQLQSYLLP HHHHCCEEEECCCCCCCEEEEEEECCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC KNHPNTKGIRIHTTYLPMRQVGGDLYDWVELDENRLILLIADVAGHGVPAAFVSSMVKVQ CCCCCCCCEEEEEEECCHHHHCCCHHHHEEECCCCEEEEEEECCCCCCCHHHHHHHHHHH FRESTKSIHSPKLILEHMNQALTSLVSRYFITACCALVDTKENTIIFSTAGHPNPIIFNK HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH IQKRFEFMKIKGPIIGWKESFTFVEWKHQMQKGDRYFFFTDGVTEARAENKLFGEGKILD HHHHHHHEEECCCEECCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCHHHH LLEKGKDKDIKSLSQEIVVQITKYSEAELKDDVTFFFVDII HHHCCCCCHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEEC >Mature Secondary Structure MRILSFFFPIFFSTIFSLVAEPVSISANSVVTLSENWTFTTNGVTNPIQVGKGLSLQGIL CHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCEEEEECCCCCHHHHCCCCCCCCCC PPVEGYYETQFIYKPSNKPLGIYLDRVQEVDTFIVNGIRLGQTGSVTNDGTYLPNWYYKR CCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHE LYYIPNHVLKENSTNQLKIEIHFRNKTFQGGLFRRVPIMGNYDKLHEQILIEDGRDFCFI EEECCCHHHCCCCCCEEEEEEEECCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCHHHH MLFFGIGAYQIFSILLKRQAKTNFYLLLSTLIFVMWRLPLLNISYTYTDFTFFFWLKVFF HHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHH TSQTLLPVSIFLFSYSLFQNKLSLKERLLVLFLITIAFVQTWNIELPTRILLLRIWEFSL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH LFIVFFILRAVIRAARAKRTEAYFLSIGFICICFGATFDIIIDVTSGKNIYLTQYGFLIL HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEHHHHHHH MILSGVAISYRNAKNETELSILTKDLEIRVRERTIELREKNQDLEQDLFFASQLQSYLLP HHHHCCEEEECCCCCCCEEEEEEECCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC KNHPNTKGIRIHTTYLPMRQVGGDLYDWVELDENRLILLIADVAGHGVPAAFVSSMVKVQ CCCCCCCCEEEEEEECCHHHHCCCHHHHEEECCCCEEEEEEECCCCCCCHHHHHHHHHHH FRESTKSIHSPKLILEHMNQALTSLVSRYFITACCALVDTKENTIIFSTAGHPNPIIFNK HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH IQKRFEFMKIKGPIIGWKESFTFVEWKHQMQKGDRYFFFTDGVTEARAENKLFGEGKILD HHHHHHHEEECCCEECCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCHHHH LLEKGKDKDIKSLSQEIVVQITKYSEAELKDDVTFFFVDII HHHCCCCCHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]