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The map label for this gene is lytT [H]

Identifier: 183222359

GI number: 183222359

Start: 3126749

End: 3127486

Strand: Direct

Name: lytT [H]

Synonym: LEPBI_I3012

Alternate gene names: 183222359

Gene position: 3126749-3127486 (Clockwise)

Preceding gene: 183222358

Following gene: 183222360

Centisome position: 86.86

GC content: 35.91

Gene sequence:

>738_bases
ATGGAACCAACACCTTATTCAGTATTGATCATCGAAGATGAGTATCCTGCTCGTATGCTGATGATGGACTATGTTTTGAA
TTGTCCTGAATTAAAACTTGCTGGTATTGCAGAAAGTGGTGACAAAGCCAATACGCTGATCAACGAGAAAAAATTCGATT
TAGTTTTTATGGACATCAATCTTCCCGTTGTCAATGGGATGGATATTCTAAGGTCTAACCATTCGAAATCTACTTTTTTT
ATCATCACAACAGCATACAGCGAACATGCCGTAGAAGCATTTGATTTGGATGCAACAGATTACCTCTTAAAACCATTTTC
ATTTGAAAGATTTCGAAAATCAGTAGAAAAGGCGCTTCGCTTTTTGCAAGAATCTAAACAAAACAACTCAAATGAAAATC
TAAACAAAATTCATTTGAAAATCCAATCAGATTCTGCAGTTTTTTTATTACCGTATCCAGACATCCAATTCATTTCCGCA
AATAACAAAAGTTGCGTGATCCATACTACTCAAAAAGATTACGAAACACCAAAATTATTGAAAGAAATTGAAGAAAAATT
GCCTACAAACCAATTCGTTCGAATTCACAAAGGATTTTTAGTGAACTTAAGTTATGTGGCAAGCCTCCGGTATGACAAGG
GTGGATCCTATACAATCCAATTAAAAAATGAGGATGAAACCACTCTCCCCGTGGGACGATCCTATGCTCAGTCCCTAAAA
GAAGCACTCAAACTCTAA

Upstream 100 bases:

>100_bases
CATTATCCCAAGAAATTGTAGTTCAAATCACTAAGTATTCTGAAGCAGAATTAAAAGATGATGTTACATTTTTCTTTGTT
GATATAATTTAAGTTAGTAT

Downstream 100 bases:

>100_bases
ATTTTCCGATTCACTCCCCTATAGGTAGCGTTCATTCCCAATCAAGTAGGGAACATAGAATCTACGAATTATTCCATTGA
CGTTCCGATCCTAAATGGGA

Product: putative two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MEPTPYSVLIIEDEYPARMLMMDYVLNCPELKLAGIAESGDKANTLINEKKFDLVFMDINLPVVNGMDILRSNHSKSTFF
IITTAYSEHAVEAFDLDATDYLLKPFSFERFRKSVEKALRFLQESKQNNSNENLNKIHLKIQSDSAVFLLPYPDIQFISA
NNKSCVIHTTQKDYETPKLLKEIEEKLPTNQFVRIHKGFLVNLSYVASLRYDKGGSYTIQLKNEDETTLPVGRSYAQSLK
EALKL

Sequences:

>Translated_245_residues
MEPTPYSVLIIEDEYPARMLMMDYVLNCPELKLAGIAESGDKANTLINEKKFDLVFMDINLPVVNGMDILRSNHSKSTFF
IITTAYSEHAVEAFDLDATDYLLKPFSFERFRKSVEKALRFLQESKQNNSNENLNKIHLKIQSDSAVFLLPYPDIQFISA
NNKSCVIHTTQKDYETPKLLKEIEEKLPTNQFVRIHKGFLVNLSYVASLRYDKGGSYTIQLKNEDETTLPVGRSYAQSLK
EALKL
>Mature_245_residues
MEPTPYSVLIIEDEYPARMLMMDYVLNCPELKLAGIAESGDKANTLINEKKFDLVFMDINLPVVNGMDILRSNHSKSTFF
IITTAYSEHAVEAFDLDATDYLLKPFSFERFRKSVEKALRFLQESKQNNSNENLNKIHLKIQSDSAVFLLPYPDIQFISA
NNKSCVIHTTQKDYETPKLLKEIEEKLPTNQFVRIHKGFLVNLSYVASLRYDKGGSYTIQLKNEDETTLPVGRSYAQSLK
EALKL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=248, Percent_Identity=27.0161290322581, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI87082052, Length=244, Percent_Identity=29.0983606557377, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28074; Mature: 28074

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPTPYSVLIIEDEYPARMLMMDYVLNCPELKLAGIAESGDKANTLINEKKFDLVFMDIN
CCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCCEEEEEEEEC
LPVVNGMDILRSNHSKSTFFIITTAYSEHAVEAFDLDATDYLLKPFSFERFRKSVEKALR
CCEECCHHHHHCCCCCCEEEEEEECCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHH
FLQESKQNNSNENLNKIHLKIQSDSAVFLLPYPDIQFISANNKSCVIHTTQKDYETPKLL
HHHHHHCCCCCCCEEEEEEEEECCCEEEEEECCCEEEEECCCCEEEEEECCCCCCCHHHH
KEIEEKLPTNQFVRIHKGFLVNLSYVASLRYDKGGSYTIQLKNEDETTLPVGRSYAQSLK
HHHHHHCCCCCEEEEECCEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHH
EALKL
HHHCC
>Mature Secondary Structure
MEPTPYSVLIIEDEYPARMLMMDYVLNCPELKLAGIAESGDKANTLINEKKFDLVFMDIN
CCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCCEEEEEEEEC
LPVVNGMDILRSNHSKSTFFIITTAYSEHAVEAFDLDATDYLLKPFSFERFRKSVEKALR
CCEECCHHHHHCCCCCCEEEEEEECCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHH
FLQESKQNNSNENLNKIHLKIQSDSAVFLLPYPDIQFISANNKSCVIHTTQKDYETPKLL
HHHHHHCCCCCCCEEEEEEEEECCCEEEEEECCCEEEEECCCCEEEEEECCCCCCCHHHH
KEIEEKLPTNQFVRIHKGFLVNLSYVASLRYDKGGSYTIQLKNEDETTLPVGRSYAQSLK
HHHHHHCCCCCEEEEECCEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHH
EALKL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]