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The map label for this gene is arsC [H]

Identifier: 183222221

GI number: 183222221

Start: 2965337

End: 2965756

Strand: Direct

Name: arsC [H]

Synonym: LEPBI_I2872

Alternate gene names: 183222221

Gene position: 2965337-2965756 (Clockwise)

Preceding gene: 183222220

Following gene: 183222222

Centisome position: 82.38

GC content: 39.29

Gene sequence:

>420_bases
ATGAAAAAAAATATTTTAATCCTTTGTACGGGGAATAGTTGTCGGAGCCAAATCGCAGAAGGTTGGATGCGTTTTTATGC
AAAGGACAAAGCCAATGTGTATAGTGCGGGAATCGAAACACATGGTGTGAATCCAAAGGCAATCGCCACAATGAAAGAAG
TGGGAATTGATATCTCAAGTCACACATCCAACCACATCAATGAATATAAGGACATCCAATTTGATTTTTTAATCACAGTT
TGTGATCATGCGAAGGAAAATTGTCCTTACTTTCCGAGTGATGCCAAACGGTTTCACCACAACTTCAGTGACCCTTCCAA
AAAACAAGGAACGGAAACGGAAATTTGGCAAGCATTTGCAGAGACAAGAGAAGAGATTCGCACCTATTGTGAAAATTTTG
TGAACCAGGAAGTAAACTAA

Upstream 100 bases:

>100_bases
TGCATTGACTGGGAAAATTTCAACCAAATGTCAGATGAGTTTAGCAAATGTATCAATGGAATCAAAGAATACCAAAAGGA
AAATGGGAGCTGTTGTTAAG

Downstream 100 bases:

>100_bases
CATGGAAAAACCAATGAAATCAATCCCTTGGATCGAATTTAAAAAACATTTAGAACTCTATCCTGAATTACAATTGAAAT
TTGTATATAATAATGATCAG

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MKKNILILCTGNSCRSQIAEGWMRFYAKDKANVYSAGIETHGVNPKAIATMKEVGIDISSHTSNHINEYKDIQFDFLITV
CDHAKENCPYFPSDAKRFHHNFSDPSKKQGTETEIWQAFAETREEIRTYCENFVNQEVN

Sequences:

>Translated_139_residues
MKKNILILCTGNSCRSQIAEGWMRFYAKDKANVYSAGIETHGVNPKAIATMKEVGIDISSHTSNHINEYKDIQFDFLITV
CDHAKENCPYFPSDAKRFHHNFSDPSKKQGTETEIWQAFAETREEIRTYCENFVNQEVN
>Mature_139_residues
MKKNILILCTGNSCRSQIAEGWMRFYAKDKANVYSAGIETHGVNPKAIATMKEVGIDISSHTSNHINEYKDIQFDFLITV
CDHAKENCPYFPSDAKRFHHNFSDPSKKQGTETEIWQAFAETREEIRTYCENFVNQEVN

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15985; Mature: 15985

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNILILCTGNSCRSQIAEGWMRFYAKDKANVYSAGIETHGVNPKAIATMKEVGIDISS
CCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCC
HTSNHINEYKDIQFDFLITVCDHAKENCPYFPSDAKRFHHNFSDPSKKQGTETEIWQAFA
CCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHH
ETREEIRTYCENFVNQEVN
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKNILILCTGNSCRSQIAEGWMRFYAKDKANVYSAGIETHGVNPKAIATMKEVGIDISS
CCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCC
HTSNHINEYKDIQFDFLITVCDHAKENCPYFPSDAKRFHHNFSDPSKKQGTETEIWQAFA
CCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHH
ETREEIRTYCENFVNQEVN
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]