Click here to switch to the map view.

The map label for this gene is fur [C]

Identifier: 183222199

GI number: 183222199

Start: 2939295

End: 2939717

Strand: Direct

Name: fur [C]

Synonym: LEPBI_I2849

Alternate gene names: 183222199

Gene position: 2939295-2939717 (Clockwise)

Preceding gene: 183222198

Following gene: 183222200

Centisome position: 81.65

GC content: 38.53

Gene sequence:

>423_bases
ATGGCTGGTGATCCTTCTCAAATTCTCAAAAAAATCGGGCTCAAAGTAACTAAAAACAGAGAACAAGTTTTATCCATTTT
ACAAGGATCCACAAGACCACTCAACCACCAAGAAATCATGGAAAAACTTCCCAAAGAAGAGTCTTGGGACAGAGTTACAA
TCTACCGTGCTTTATCAGACCTAGAAGAAAAAAATCTTTTGAACTCACTTCATTCTGCAGATCGAGTCACCTACTTTGAG
CTAAAATCAGATGGGAACCATATTGTGTCTGCTGCACATGGACATTTGATTTGTAATGTCTGCGGAAAAATCGAATGCAT
TGACGATCCTTGGAATGGGATGCCTTCTTCAAAACAACTCAAAGGTTTCACAACTGAATCTGTTGAAATCGTTTTTAGAG
GCAAGTGTAGAAATTGCCAATAG

Upstream 100 bases:

>100_bases
AAAAGTACACACACAAATGGGGATTCGTTATTGGGAAATCTGGAAATCCAATGTGATTTTAGAATAGACAATCTCTCCTT
ATCTAAGATAACCATTTTAT

Downstream 100 bases:

>100_bases
ACCAGAGCCTCACTACTTTAATCCCCACTTTACATAAAAAACATTTAGATACGATCAATTTTGCATTAAAAAATGCAGGA
TTTGAATGTTATCTCGTAGG

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric Uptake Regulator Family Protein; FUR Family Transcriptional Regulator; Fur Family Ferric Uptake Regulator; Ferric Uptake Trancriptional Regulator Fur Family; Ferric Uptake Regulation Protein; Ferric-Uptake Regulator; Regulatory Protein; Transcription Regulator Protein; Transcriptional Regulator Fur Family; Ferric Uptake Regulation Protein Fur; FUR Family Regulator Protein

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MAGDPSQILKKIGLKVTKNREQVLSILQGSTRPLNHQEIMEKLPKEESWDRVTIYRALSDLEEKNLLNSLHSADRVTYFE
LKSDGNHIVSAAHGHLICNVCGKIECIDDPWNGMPSSKQLKGFTTESVEIVFRGKCRNCQ

Sequences:

>Translated_140_residues
MAGDPSQILKKIGLKVTKNREQVLSILQGSTRPLNHQEIMEKLPKEESWDRVTIYRALSDLEEKNLLNSLHSADRVTYFE
LKSDGNHIVSAAHGHLICNVCGKIECIDDPWNGMPSSKQLKGFTTESVEIVFRGKCRNCQ
>Mature_139_residues
AGDPSQILKKIGLKVTKNREQVLSILQGSTRPLNHQEIMEKLPKEESWDRVTIYRALSDLEEKNLLNSLHSADRVTYFEL
KSDGNHIVSAAHGHLICNVCGKIECIDDPWNGMPSSKQLKGFTTESVEIVFRGKCRNCQ

Specific function: Acts As A Global Negative Controlling Element, Employing Fe(2+) As A Cofactor To Bind The Operator Of The Repressed Genes. Regulates The Expression Of Several Outer-Membrane Proteins Including The Iron Transport Operon. [C]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 15807; Mature: 15676

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGDPSQILKKIGLKVTKNREQVLSILQGSTRPLNHQEIMEKLPKEESWDRVTIYRALSD
CCCCHHHHHHHHCCEEECCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
LEEKNLLNSLHSADRVTYFELKSDGNHIVSAAHGHLICNVCGKIECIDDPWNGMPSSKQL
HHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCEEEEECCCCEEEECCCCCCCCCCCCC
KGFTTESVEIVFRGKCRNCQ
CCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
AGDPSQILKKIGLKVTKNREQVLSILQGSTRPLNHQEIMEKLPKEESWDRVTIYRALSD
CCCHHHHHHHHCCEEECCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
LEEKNLLNSLHSADRVTYFELKSDGNHIVSAAHGHLICNVCGKIECIDDPWNGMPSSKQL
HHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCEEEEECCCCEEEECCCCCCCCCCCCC
KGFTTESVEIVFRGKCRNCQ
CCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA