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The map label for this gene is cmk [H]

Identifier: 183221955

GI number: 183221955

Start: 2682853

End: 2683605

Strand: Reverse

Name: cmk [H]

Synonym: LEPBI_I2596

Alternate gene names: 183221955

Gene position: 2683605-2682853 (Counterclockwise)

Preceding gene: 183221957

Following gene: 183221954

Centisome position: 74.55

GC content: 46.75

Gene sequence:

>753_bases
ATGAGTTTACAATCGATTGAAAACGTAATCGCCATTGATGGTCCTGCTGGATCTGGGAAAAGTACCCTTGCCCGAATGAT
TGCCCATAAACTGGGGTTTCATTATTTGGATTCGGGCGCATTTTACCGGGCATTGACCTTTGCCCTCCTGGAAAAATTCA
AAGAAACTAAGGAAGACGAATCCAAATTCCCTTTTTATACTGAAAAATTGGCCGATGCCACCCTCCTTGAGAAGGACGAA
TCCGAATTTGGTTTTTCCGTAGCCGCGATTCCCGTTCATTGTGAACTTTCCTCTACCGGTGAGAATTTGATGTTTCTCGG
AGAAAGGGACATAAGCCGAGAAATCCGTGACCCGGAAATCACGAAAAAAATCCGTTACATAGCCCCAAGGCGTGCTTTTC
GCGAAATCCTAAACCGCCACATCCGCGAATTTGCCAAAACCCATAGATTGGTCATGGATGGTCGGGACATCGGGACAGAA
GTGTTTCCTAAGTCCAAATTTAAATTTTTTCTCACTGCCTCTGTGGAAGTGCGTGCCAAACGCCGATACGATGAACTAGT
CACAAAAGGCTTCAAAGCCGACCTAAACCACATCAAAGAAGAAATTGTGGCCAGGGACGAAAGTGACACCACCCGAACTG
TGGCCCCCCTGAAGCAAGCTTCGGACGCAATCCTGATTGACACGAGCACCCTCGACACAGAAACTGTCCTAAATACTATC
CTGTCCAAGGTTTCACCCTCTGGGCAAATCTAA

Upstream 100 bases:

>100_bases
CCATATACAGCCAGTTAGCTTACGTGGAACGCCTGGCGAGAAGTCCCAAGAATTCCTCTAGACAAAGTGAATTCCTCTCG
TAGAATTTGGTCATCAAGTT

Downstream 100 bases:

>100_bases
GTTTTGTATCCCGGTAACCATTGAATTCAACCAACCCATCCTCCCCCAAAAATGAGACCACTTCCTTCGGCGAATTATTA
GAGAAGTGGGAATCGCAGTC

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSLQSIENVIAIDGPAGSGKSTLARMIAHKLGFHYLDSGAFYRALTFALLEKFKETKEDESKFPFYTEKLADATLLEKDE
SEFGFSVAAIPVHCELSSTGENLMFLGERDISREIRDPEITKKIRYIAPRRAFREILNRHIREFAKTHRLVMDGRDIGTE
VFPKSKFKFFLTASVEVRAKRRYDELVTKGFKADLNHIKEEIVARDESDTTRTVAPLKQASDAILIDTSTLDTETVLNTI
LSKVSPSGQI

Sequences:

>Translated_250_residues
MSLQSIENVIAIDGPAGSGKSTLARMIAHKLGFHYLDSGAFYRALTFALLEKFKETKEDESKFPFYTEKLADATLLEKDE
SEFGFSVAAIPVHCELSSTGENLMFLGERDISREIRDPEITKKIRYIAPRRAFREILNRHIREFAKTHRLVMDGRDIGTE
VFPKSKFKFFLTASVEVRAKRRYDELVTKGFKADLNHIKEEIVARDESDTTRTVAPLKQASDAILIDTSTLDTETVLNTI
LSKVSPSGQI
>Mature_249_residues
SLQSIENVIAIDGPAGSGKSTLARMIAHKLGFHYLDSGAFYRALTFALLEKFKETKEDESKFPFYTEKLADATLLEKDES
EFGFSVAAIPVHCELSSTGENLMFLGERDISREIRDPEITKKIRYIAPRRAFREILNRHIREFAKTHRLVMDGRDIGTEV
FPKSKFKFFLTASVEVRAKRRYDELVTKGFKADLNHIKEEIVARDESDTTRTVAPLKQASDAILIDTSTLDTETVLNTIL
SKVSPSGQI

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787139, Length=240, Percent_Identity=36.25, Blast_Score=141, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003136
- InterPro:   IPR011994 [H]

Pfam domain/function: PF02224 Cytidylate_kin [H]

EC number: =2.7.4.14 [H]

Molecular weight: Translated: 28253; Mature: 28121

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQSIENVIAIDGPAGSGKSTLARMIAHKLGFHYLDSGAFYRALTFALLEKFKETKEDE
CCHHHHCCEEEECCCCCCCHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHCCCCC
SKFPFYTEKLADATLLEKDESEFGFSVAAIPVHCELSSTGENLMFLGERDISREIRDPEI
CCCCCHHHHHHHHHHHCCCCHHHCEEEEEEEEEEEECCCCCCEEEECCHHHHHHCCCHHH
TKKIRYIAPRRAFREILNRHIREFAKTHRLVMDGRDIGTEVFPKSKFKFFLTASVEVRAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEHHHHHH
RRYDELVTKGFKADLNHIKEEIVARDESDTTRTVAPLKQASDAILIDTSTLDTETVLNTI
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
LSKVSPSGQI
HHHCCCCCCC
>Mature Secondary Structure 
SLQSIENVIAIDGPAGSGKSTLARMIAHKLGFHYLDSGAFYRALTFALLEKFKETKEDE
CHHHHCCEEEECCCCCCCHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHCCCCC
SKFPFYTEKLADATLLEKDESEFGFSVAAIPVHCELSSTGENLMFLGERDISREIRDPEI
CCCCCHHHHHHHHHHHCCCCHHHCEEEEEEEEEEEECCCCCCEEEECCHHHHHHCCCHHH
TKKIRYIAPRRAFREILNRHIREFAKTHRLVMDGRDIGTEVFPKSKFKFFLTASVEVRAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEHHHHHH
RRYDELVTKGFKADLNHIKEEIVARDESDTTRTVAPLKQASDAILIDTSTLDTETVLNTI
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
LSKVSPSGQI
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA