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The map label for this gene is aroB [H]

Identifier: 183221943

GI number: 183221943

Start: 2669785

End: 2670885

Strand: Reverse

Name: aroB [H]

Synonym: LEPBI_I2582

Alternate gene names: 183221943

Gene position: 2670885-2669785 (Counterclockwise)

Preceding gene: 183221944

Following gene: 183221942

Centisome position: 74.2

GC content: 39.33

Gene sequence:

>1101_bases
ATGAAGTTATCAGAACGAAAAGTTGTAGGCTCGGGTTTTGTTTACCCCGTAGAATTACATGAAGACTTTGTTGGTCTTTC
TGAAAAACTTGGATCACTCAAAAAAATCTCCCATGCATTCGTTCTCACCAGTCGCGAAATTGCAGGCATCTACGAAAAAT
ATTTAATCAAAGAATTAAAAGCCAGTTCCATCCCGTTTTCTTTTATCTATTTAAAGGCGGGTGAAAAAAACAAACACATT
GACCGCGTCAAAAAAGTATACCACCAACTCATCGAAGCAGATGCAGATCGAAATGCTGTCATCATTGCATTTGGCGGTGG
AGTGGTTGGCGACTTTGCAGGATTCATCGCGGCTACTTACCAAAGGGGAATTCGATTCATCCAAGTGCCAACAACCTTAC
TTGCTTGTGTGGATTCGTCTGTAGGTGGAAAGGTTGCTGTGAATGTAGATTCAGGCAAAAATATGGTGGGTGCTTTTTAC
CAACCTGAATTTGTTTTTGCACCTCTCTTTACTCTTTCAACATTACCAAAAAAAGAGTGGAGTTGTGGTCTTGCAGAAGT
CGCCAAACATTCGTTTTTGGATGGAGGGGATTTTTTTGAAAGAATTTCTAATTCCAAACGTGCCGATTTTTATGAAAAAT
CAGAGACTCTCCGTTATGCGATCGAAGAATCAGTGCGTGTCAAATCATCCATTGTGTCGCAAGATGAAAAGGAGTCCGGT
TTACGTGCTGTTCTCAATTTAGGTCATACGACAGGACACGCGATCGAATCACTCACCTTATACAAAAAATACTCTCATGG
GGAAGCAGTTTCTGTAGGTCTTGTTACCGCGTTGTTATTATCCAAAGAAATATTAGGTTTTTCGGATTCCAATTTCCAAA
AAGCAATTTCTCTTATGTTACAATTAGAGTTGCCAACAGTTCTAGAAGAAAAACCAGAATTAGTTTTGAAACACATGGAA
CATGACAAAAAAAAGGATGGGAATACCTTGAAGTTTGTCCTACTGGAAGATTTTGGTAAACCAAAGTTTGGAGTAACAGT
GGAACGAAAAACCATTTTGGAAATCTTAAAACGCCACAAAGGAATGAACCTCAATGGGTAG

Upstream 100 bases:

>100_bases
AGATTTTGGAGATGGATCTAAGGCCTGACATAAAACATTACTTTCGGGCTAAAAGCACAAATAAACCTCGATATATTTCA
AGCCCATGGGTGAATGAACC

Downstream 100 bases:

>100_bases
TGGAAGTTTAAAAGAATTTTATTTAGATCTTAATCCTTTAACTCTTCTCAGAAGTTCGAATCGGGAATTTGCTGAGACGC
TGATACTTTTTGCCTATATG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKLSERKVVGSGFVYPVELHEDFVGLSEKLGSLKKISHAFVLTSREIAGIYEKYLIKELKASSIPFSFIYLKAGEKNKHI
DRVKKVYHQLIEADADRNAVIIAFGGGVVGDFAGFIAATYQRGIRFIQVPTTLLACVDSSVGGKVAVNVDSGKNMVGAFY
QPEFVFAPLFTLSTLPKKEWSCGLAEVAKHSFLDGGDFFERISNSKRADFYEKSETLRYAIEESVRVKSSIVSQDEKESG
LRAVLNLGHTTGHAIESLTLYKKYSHGEAVSVGLVTALLLSKEILGFSDSNFQKAISLMLQLELPTVLEEKPELVLKHME
HDKKKDGNTLKFVLLEDFGKPKFGVTVERKTILEILKRHKGMNLNG

Sequences:

>Translated_366_residues
MKLSERKVVGSGFVYPVELHEDFVGLSEKLGSLKKISHAFVLTSREIAGIYEKYLIKELKASSIPFSFIYLKAGEKNKHI
DRVKKVYHQLIEADADRNAVIIAFGGGVVGDFAGFIAATYQRGIRFIQVPTTLLACVDSSVGGKVAVNVDSGKNMVGAFY
QPEFVFAPLFTLSTLPKKEWSCGLAEVAKHSFLDGGDFFERISNSKRADFYEKSETLRYAIEESVRVKSSIVSQDEKESG
LRAVLNLGHTTGHAIESLTLYKKYSHGEAVSVGLVTALLLSKEILGFSDSNFQKAISLMLQLELPTVLEEKPELVLKHME
HDKKKDGNTLKFVLLEDFGKPKFGVTVERKTILEILKRHKGMNLNG
>Mature_366_residues
MKLSERKVVGSGFVYPVELHEDFVGLSEKLGSLKKISHAFVLTSREIAGIYEKYLIKELKASSIPFSFIYLKAGEKNKHI
DRVKKVYHQLIEADADRNAVIIAFGGGVVGDFAGFIAATYQRGIRFIQVPTTLLACVDSSVGGKVAVNVDSGKNMVGAFY
QPEFVFAPLFTLSTLPKKEWSCGLAEVAKHSFLDGGDFFERISNSKRADFYEKSETLRYAIEESVRVKSSIVSQDEKESG
LRAVLNLGHTTGHAIESLTLYKKYSHGEAVSVGLVTALLLSKEILGFSDSNFQKAISLMLQLELPTVLEEKPELVLKHME
HDKKKDGNTLKFVLLEDFGKPKFGVTVERKTILEILKRHKGMNLNG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=352, Percent_Identity=38.3522727272727, Blast_Score=217, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320332, Length=333, Percent_Identity=36.036036036036, Blast_Score=184, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40627; Mature: 40627

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSERKVVGSGFVYPVELHEDFVGLSEKLGSLKKISHAFVLTSREIAGIYEKYLIKELK
CCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHH
ASSIPFSFIYLKAGEKNKHIDRVKKVYHQLIEADADRNAVIIAFGGGVVGDFAGFIAATY
HCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHH
QRGIRFIQVPTTLLACVDSSVGGKVAVNVDSGKNMVGAFYQPEFVFAPLFTLSTLPKKEW
HHCCEEEEHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHCCCCCCC
SCGLAEVAKHSFLDGGDFFERISNSKRADFYEKSETLRYAIEESVRVKSSIVSQDEKESG
CCCHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LRAVLNLGHTTGHAIESLTLYKKYSHGEAVSVGLVTALLLSKEILGFSDSNFQKAISLML
HHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QLELPTVLEEKPELVLKHMEHDKKKDGNTLKFVLLEDFGKPKFGVTVERKTILEILKRHK
HCCCCHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEECHHHHHHHHHHHC
GMNLNG
CCCCCC
>Mature Secondary Structure
MKLSERKVVGSGFVYPVELHEDFVGLSEKLGSLKKISHAFVLTSREIAGIYEKYLIKELK
CCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHH
ASSIPFSFIYLKAGEKNKHIDRVKKVYHQLIEADADRNAVIIAFGGGVVGDFAGFIAATY
HCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHH
QRGIRFIQVPTTLLACVDSSVGGKVAVNVDSGKNMVGAFYQPEFVFAPLFTLSTLPKKEW
HHCCEEEEHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHCCCCCCC
SCGLAEVAKHSFLDGGDFFERISNSKRADFYEKSETLRYAIEESVRVKSSIVSQDEKESG
CCCHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LRAVLNLGHTTGHAIESLTLYKKYSHGEAVSVGLVTALLLSKEILGFSDSNFQKAISLML
HHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QLELPTVLEEKPELVLKHMEHDKKKDGNTLKFVLLEDFGKPKFGVTVERKTILEILKRHK
HCCCCHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEECHHHHHHHHHHHC
GMNLNG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA