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The map label for this gene is 183221942

Identifier: 183221942

GI number: 183221942

Start: 2668896

End: 2669792

Strand: Reverse

Name: 183221942

Synonym: LEPBI_I2581

Alternate gene names: NA

Gene position: 2669792-2668896 (Counterclockwise)

Preceding gene: 183221943

Following gene: 183221941

Centisome position: 74.17

GC content: 35.45

Gene sequence:

>897_bases
ATGGGTAGTGGAAGTTTAAAAGAATTTTATTTAGATCTTAATCCTTTAACTCTTCTCAGAAGTTCGAATCGGGAATTTGC
TGAGACGCTGATACTTTTTGCCTATATGGTTGTCTTTGCTGTGATTTGTTACAAAATCACAATGTTTCTTGTAGAGAGAG
TCAAACCTGCGATAGATCCCGTTCACGAATACAACCGAAGAAAAGTTGCAAGGATGGGATTTATTCTCGTTTTTGGAATT
GCTTACCTCCCCGTTATTTTTTCTAGTTTATCGTTACTTCCCACAGTTCTTGGTCTTGCAGGAGCTGGTATTGTCATTTC
ACTCAAAGAAGTATGGCTCAACATGGTGGGTTGGTTTATGATCATGGGTGCTAACGGTTTTAAAGTGGGAGACAGGATTG
AAATTGAGAACATCAAAGGAGATGTTGTCAATATTGGATTTTTTAAATTTACCTTACTTGAAATTGCACCAGATCCGAGG
TTTGAACAATCCACAAACAGACTCATTCATTTTCCAAACTATAACATCGTCCTGCATCGATTTTTTATTGTTTCAGAAAC
TATGGATTTTGTTTGGGATGAGTTCCGAATCTATTTAGATTTAAAATCAAACTGGCAAAAAGCAGAAAAGATTTGTACTC
AAATATTACATGAAGAATTGGTACTCGCACCTGAACTTGTAGAATCAAAAATCAGAGAAATGTCAAAAAACTATCTTGTG
AGACTTGGAAAAACAACACCAATCGTTTATACTTCTTTGGAACCAGAAGGTACAATTCTTATGTGTTTACGTTATCTAAC
GCCCATCCGATCGAAACGTCTCAATCGTATCTTAATCTCAAAAGAAATTTTAACTAAATTCAAAGAAGAAAATGACATCT
ACATCCACACCCATTAA

Upstream 100 bases:

>100_bases
TTTGTCCTACTGGAAGATTTTGGTAAACCAAAGTTTGGAGTAACAGTGGAACGAAAAACCATTTTGGAAATCTTAAAACG
CCACAAAGGAATGAACCTCA

Downstream 100 bases:

>100_bases
AGACAATTCCTTTTGGATTTTTATCTCTCTCCTAGCAGTTGTTTTACTGTCTGGTGTTGTATTTGGTCCCTGCAAGGGAA
GTGTGGAAAGACCATCTACT

Product: putative small conductance mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MGSGSLKEFYLDLNPLTLLRSSNREFAETLILFAYMVVFAVICYKITMFLVERVKPAIDPVHEYNRRKVARMGFILVFGI
AYLPVIFSSLSLLPTVLGLAGAGIVISLKEVWLNMVGWFMIMGANGFKVGDRIEIENIKGDVVNIGFFKFTLLEIAPDPR
FEQSTNRLIHFPNYNIVLHRFFIVSETMDFVWDEFRIYLDLKSNWQKAEKICTQILHEELVLAPELVESKIREMSKNYLV
RLGKTTPIVYTSLEPEGTILMCLRYLTPIRSKRLNRILISKEILTKFKEENDIYIHTH

Sequences:

>Translated_298_residues
MGSGSLKEFYLDLNPLTLLRSSNREFAETLILFAYMVVFAVICYKITMFLVERVKPAIDPVHEYNRRKVARMGFILVFGI
AYLPVIFSSLSLLPTVLGLAGAGIVISLKEVWLNMVGWFMIMGANGFKVGDRIEIENIKGDVVNIGFFKFTLLEIAPDPR
FEQSTNRLIHFPNYNIVLHRFFIVSETMDFVWDEFRIYLDLKSNWQKAEKICTQILHEELVLAPELVESKIREMSKNYLV
RLGKTTPIVYTSLEPEGTILMCLRYLTPIRSKRLNRILISKEILTKFKEENDIYIHTH
>Mature_297_residues
GSGSLKEFYLDLNPLTLLRSSNREFAETLILFAYMVVFAVICYKITMFLVERVKPAIDPVHEYNRRKVARMGFILVFGIA
YLPVIFSSLSLLPTVLGLAGAGIVISLKEVWLNMVGWFMIMGANGFKVGDRIEIENIKGDVVNIGFFKFTLLEIAPDPRF
EQSTNRLIHFPNYNIVLHRFFIVSETMDFVWDEFRIYLDLKSNWQKAEKICTQILHEELVLAPELVESKIREMSKNYLVR
LGKTTPIVYTSLEPEGTILMCLRYLTPIRSKRLNRILISKEILTKFKEENDIYIHTH

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 34541; Mature: 34410

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGSLKEFYLDLNPLTLLRSSNREFAETLILFAYMVVFAVICYKITMFLVERVKPAIDP
CCCCCCCHHEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHEYNRRKVARMGFILVFGIAYLPVIFSSLSLLPTVLGLAGAGIVISLKEVWLNMVGWFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
IMGANGFKVGDRIEIENIKGDVVNIGFFKFTLLEIAPDPRFEQSTNRLIHFPNYNIVLHR
HCCCCCCCCCCEEEEECCCCCEEEEHHHHEEEEEECCCCCCCCCCCCEEECCCCCEEHHH
FFIVSETMDFVWDEFRIYLDLKSNWQKAEKICTQILHEELVLAPELVESKIREMSKNYLV
HHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
RLGKTTPIVYTSLEPEGTILMCLRYLTPIRSKRLNRILISKEILTKFKEENDIYIHTH
EECCCCCEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure 
GSGSLKEFYLDLNPLTLLRSSNREFAETLILFAYMVVFAVICYKITMFLVERVKPAIDP
CCCCCCHHEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHEYNRRKVARMGFILVFGIAYLPVIFSSLSLLPTVLGLAGAGIVISLKEVWLNMVGWFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
IMGANGFKVGDRIEIENIKGDVVNIGFFKFTLLEIAPDPRFEQSTNRLIHFPNYNIVLHR
HCCCCCCCCCCEEEEECCCCCEEEEHHHHEEEEEECCCCCCCCCCCCEEECCCCCEEHHH
FFIVSETMDFVWDEFRIYLDLKSNWQKAEKICTQILHEELVLAPELVESKIREMSKNYLV
HHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
RLGKTTPIVYTSLEPEGTILMCLRYLTPIRSKRLNRILISKEILTKFKEENDIYIHTH
EECCCCCEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]