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The map label for this gene is ychK [C]

Identifier: 183221885

GI number: 183221885

Start: 2605243

End: 2606361

Strand: Direct

Name: ychK [C]

Synonym: LEPBI_I2521

Alternate gene names: 183221885

Gene position: 2605243-2606361 (Clockwise)

Preceding gene: 183221884

Following gene: 183221886

Centisome position: 72.37

GC content: 43.16

Gene sequence:

>1119_bases
TTGTTGTTAAGTGAGGCGCATAGAACTGGTGGACTTACCGCAGAAGAAATCCGTTTTCTAGGCGATTCAGAAGAAGTCCT
TGGTCCAACCCGCGAACTTGTTTTACTTTATTCTGATCCAAATGAAAAACCAGCCAATACCGCAAACCTAACACGAATCA
GAAAAACAGATTCAGTCAGGCATATCCGCACATATAGTAATCATGGATTTGAAAGTCTAACTCGCTTCATTACAGGACGT
TCCATAGGATTCGCATTAGGCGGTGGTGGTGCAAAAGGCCTTGCCCATATCGGACTTCTAAAAGCCATGCAGGAAGAAAA
CATACCCATCGACATGATTGGAGGCACAAGTGCAGGTGCCCTTATGGCAAGTATTTATGCAATGGGTTATCATGCTCCCG
AATTAGAACGTGTCGCGAAAGCTCTTATGAGCGACAAAAAAACTTTGAATGACTATACGATACCAACGGTCTCTCTCATT
CGAGGTAAAAAGTTCAACACTGTAATCAAAAATTTTGTTGGGAATCGAATGATCGAAGATCTATGGTTACCGTATTTTGC
TGTAGCCACGAGCCTCACTAAATCCCAAAAAGTGATCTTCGATCGTGGACCTGTATGGAAAGCATTACGTGCATCGGCAT
CGATTCCAGGAATCTTACCACCGTTCTACGAAAAAAACGAACTGCTTGTTGATGGAGCCATGCTCGATAACATTCCAGGA
GCTGTGATGCGCGAGAAGGGAGCCGATTTTGTGATCTCTGTGGCGCTCTCTTCGGAAGGTGATTCCACTGCAGATGAAGT
CTTCAGTGCCATCTATGAAGAAAATAATTCGGGGGCCTTACCTTCAGCACTTCGAATGTTATTCAAACGAATCATTGGCA
AAACACAAAAACAAAAAGACGTCCCAAACCTTTTGAGTTTACTCATGCGTGCTACTTTTGTTGCCTCAGATGCGGCAAAA
GCCAAAGCGAAGGCTGAATCAGATATTTTTGCTGAATTGCCAGTAGAGCAATATGGTCTTTTCGATTGGAAAAAATTCCA
CGAACTGGTAGAGATTGGATATAATTATGGGAAGGCCAATGCCAAAAGTTGGAAAAAACAACTGGGGATAAGGGGTTAG

Upstream 100 bases:

>100_bases
ACTGTATCAAATGCAGGATTCCCATGAATTCCTAATCCTTTGCCCTGACTTTTAGGACAAACTTTGGACAGAAACAATTC
TACACCATACCAATCGCATT

Downstream 100 bases:

>100_bases
TGACCATTTTCTAGAAACTAGGAAAAAAAACTTGCATGACTTGGTTCCATTTCAAAAATTTTAGTAACAAATGTTAATCA
TTTTAATCCAAAAGAAATGA

Product: putative phopholipase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLLSEAHRTGGLTAEEIRFLGDSEEVLGPTRELVLLYSDPNEKPANTANLTRIRKTDSVRHIRTYSNHGFESLTRFITGR
SIGFALGGGGAKGLAHIGLLKAMQEENIPIDMIGGTSAGALMASIYAMGYHAPELERVAKALMSDKKTLNDYTIPTVSLI
RGKKFNTVIKNFVGNRMIEDLWLPYFAVATSLTKSQKVIFDRGPVWKALRASASIPGILPPFYEKNELLVDGAMLDNIPG
AVMREKGADFVISVALSSEGDSTADEVFSAIYEENNSGALPSALRMLFKRIIGKTQKQKDVPNLLSLLMRATFVASDAAK
AKAKAESDIFAELPVEQYGLFDWKKFHELVEIGYNYGKANAKSWKKQLGIRG

Sequences:

>Translated_372_residues
MLLSEAHRTGGLTAEEIRFLGDSEEVLGPTRELVLLYSDPNEKPANTANLTRIRKTDSVRHIRTYSNHGFESLTRFITGR
SIGFALGGGGAKGLAHIGLLKAMQEENIPIDMIGGTSAGALMASIYAMGYHAPELERVAKALMSDKKTLNDYTIPTVSLI
RGKKFNTVIKNFVGNRMIEDLWLPYFAVATSLTKSQKVIFDRGPVWKALRASASIPGILPPFYEKNELLVDGAMLDNIPG
AVMREKGADFVISVALSSEGDSTADEVFSAIYEENNSGALPSALRMLFKRIIGKTQKQKDVPNLLSLLMRATFVASDAAK
AKAKAESDIFAELPVEQYGLFDWKKFHELVEIGYNYGKANAKSWKKQLGIRG
>Mature_372_residues
MLLSEAHRTGGLTAEEIRFLGDSEEVLGPTRELVLLYSDPNEKPANTANLTRIRKTDSVRHIRTYSNHGFESLTRFITGR
SIGFALGGGGAKGLAHIGLLKAMQEENIPIDMIGGTSAGALMASIYAMGYHAPELERVAKALMSDKKTLNDYTIPTVSLI
RGKKFNTVIKNFVGNRMIEDLWLPYFAVATSLTKSQKVIFDRGPVWKALRASASIPGILPPFYEKNELLVDGAMLDNIPG
AVMREKGADFVISVALSSEGDSTADEVFSAIYEENNSGALPSALRMLFKRIIGKTQKQKDVPNLLSLLMRATFVASDAAK
AKAKAESDIFAELPVEQYGLFDWKKFHELVEIGYNYGKANAKSWKKQLGIRG

Specific function: Unknown

COG id: COG1752

COG function: function code R; Predicted esterase of the alpha-beta hydrolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 patatin domain [H]

Homologues:

Organism=Homo sapiens, GI260656039, Length=314, Percent_Identity=32.8025477707006, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI260656041, Length=314, Percent_Identity=32.8025477707006, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI116256487, Length=314, Percent_Identity=32.8025477707006, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI260656037, Length=314, Percent_Identity=32.8025477707006, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI260656043, Length=314, Percent_Identity=32.8025477707006, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI148727335, Length=393, Percent_Identity=29.5165394402036, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI148727290, Length=393, Percent_Identity=29.5165394402036, Blast_Score=172, Evalue=5e-43,
Organism=Escherichia coli, GI226510936, Length=279, Percent_Identity=29.3906810035842, Blast_Score=111, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI193204778, Length=300, Percent_Identity=33.3333333333333, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI71997299, Length=298, Percent_Identity=33.5570469798658, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71997289, Length=298, Percent_Identity=33.5570469798658, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323581, Length=294, Percent_Identity=34.6938775510204, Blast_Score=183, Evalue=3e-47,
Organism=Drosophila melanogaster, GI281376913, Length=373, Percent_Identity=34.0482573726542, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI28571388, Length=373, Percent_Identity=32.9758713136729, Blast_Score=163, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016035
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001423
- InterPro:   IPR002641
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding; PF01734 Patatin [H]

EC number: NA

Molecular weight: Translated: 40809; Mature: 40809

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSEAHRTGGLTAEEIRFLGDSEEVLGPTRELVLLYSDPNEKPANTANLTRIRKTDSVR
CCCCCCHHCCCCCHHHHHHCCCCHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCHH
HIRTYSNHGFESLTRFITGRSIGFALGGGGAKGLAHIGLLKAMQEENIPIDMIGGTSAGA
HHHHHCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHH
LMASIYAMGYHAPELERVAKALMSDKKTLNDYTIPTVSLIRGKKFNTVIKNFVGNRMIED
HHHHHHHHCCCCHHHHHHHHHHHHCHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
LWLPYFAVATSLTKSQKVIFDRGPVWKALRASASIPGILPPFYEKNELLVDGAMLDNIPG
HHHHHHHHHHHHHHCCCEEECCCCHHHHHHHCCCCCCCCCCCCCCCCEEECCHHHHCCCC
AVMREKGADFVISVALSSEGDSTADEVFSAIYEENNSGALPSALRMLFKRIIGKTQKQKD
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHCC
VPNLLSLLMRATFVASDAAKAKAKAESDIFAELPVEQYGLFDWKKFHELVEIGYNYGKAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCCHHHHHHHHHHHHCCCCCCC
AKSWKKQLGIRG
HHHHHHHHCCCC
>Mature Secondary Structure
MLLSEAHRTGGLTAEEIRFLGDSEEVLGPTRELVLLYSDPNEKPANTANLTRIRKTDSVR
CCCCCCHHCCCCCHHHHHHCCCCHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCHH
HIRTYSNHGFESLTRFITGRSIGFALGGGGAKGLAHIGLLKAMQEENIPIDMIGGTSAGA
HHHHHCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHH
LMASIYAMGYHAPELERVAKALMSDKKTLNDYTIPTVSLIRGKKFNTVIKNFVGNRMIED
HHHHHHHHCCCCHHHHHHHHHHHHCHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
LWLPYFAVATSLTKSQKVIFDRGPVWKALRASASIPGILPPFYEKNELLVDGAMLDNIPG
HHHHHHHHHHHHHHCCCEEECCCCHHHHHHHCCCCCCCCCCCCCCCCEEECCHHHHCCCC
AVMREKGADFVISVALSSEGDSTADEVFSAIYEENNSGALPSALRMLFKRIIGKTQKQKD
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHCC
VPNLLSLLMRATFVASDAAKAKAKAESDIFAELPVEQYGLFDWKKFHELVEIGYNYGKAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCCHHHHHHHHHHHHCCCCCCC
AKSWKKQLGIRG
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]