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The map label for this gene is yacO [H]

Identifier: 183221427

GI number: 183221427

Start: 2126139

End: 2126996

Strand: Reverse

Name: yacO [H]

Synonym: LEPBI_I2045

Alternate gene names: 183221427

Gene position: 2126996-2126139 (Counterclockwise)

Preceding gene: 183221428

Following gene: 183221423

Centisome position: 59.09

GC content: 40.44

Gene sequence:

>858_bases
ATGGGAAACAAATCTGATTCGGTTCCCATGAAAGCACTGAAAGTTTCTGTCCGGAATGCTGAATTCCAAATCATTTCGGC
CCTCCGGACGAATCGCACCAAACGAAGCCAAGAGAAGGAAGTTTTTGTAGAAGGAACAGAGCCCATCAAGCAATTACTCG
CCGCTCGGTGGAAGGTCACGCGGATCCTTTACCGCGAGAATGTTCCCTTATCTAGTTGGGCAAAAGAAGTTTTATCCCTC
CACAAAGAAGCAAAACAGTTTGAAGTGAAAGAAGAATTGTATTTGGAACTTTCGGAAAAGGAAACACCATCCGAATTACT
CATTACGGCAAAAATTAAGGAATCAGAGTTAACGATTCAATCCAAAAAAACGGAACAGCAATCAAACCAAAACAAACCAT
TCTACCTACTTTTTGATAGGCCCAGTGATTTAGGGAATTTCGGATCTTTATTACGTTCTGCTGATGCATTCCAAGTGGAT
TGTGTTTTTGTCATTGGACATTCAATTGATGTGTATGATCCGAAGGTCATCCGTTCCAGTTTAGGAACACTATTTCACAC
CAAACTTGTGTTTGTGAATGAATTTGAATCACTCGTAAGATTTGTCCAAATGGAGAAAAAACGGAATGGGCTTGTTGTAG
TCGGTAGCGATTCAAGTGGTGATTCAAATCTAAGAGAAGTATCCATCCAAACACCAATTTTACTCATTCTTGGTAATGAA
AAAAAAGGAATGAGCGTACAACTACAATCTATCTGTGACCGTATCGTCAAAATCCCTATGTTGGGAGTTGTCAACTCCCT
GAACGTCTCTTGCGCAGGTTCGATTTTACTATGGGAAGTAACGAGGAACAGAAATTAA

Upstream 100 bases:

>100_bases
CGACCTTGCTTCCGAACTAGATGCCAAACGAGCTATTGACCAAGGGACAAGGCTTGCTGTTTCGATTGGCTAATTTGCAC
TTCGAAACTCACCCAGTTTC

Downstream 100 bases:

>100_bases
TTCATAAAAATGACGATTGTCGTACACATTTGCATTGGAACTAACGGCAAGTGGCAATACTGCCATCAGGGTTGTATTTC
ACACTCGCTCCCGATGTGAA

Product: putative tRNA guanosine-2'-O-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MGNKSDSVPMKALKVSVRNAEFQIISALRTNRTKRSQEKEVFVEGTEPIKQLLAARWKVTRILYRENVPLSSWAKEVLSL
HKEAKQFEVKEELYLELSEKETPSELLITAKIKESELTIQSKKTEQQSNQNKPFYLLFDRPSDLGNFGSLLRSADAFQVD
CVFVIGHSIDVYDPKVIRSSLGTLFHTKLVFVNEFESLVRFVQMEKKRNGLVVVGSDSSGDSNLREVSIQTPILLILGNE
KKGMSVQLQSICDRIVKIPMLGVVNSLNVSCAGSILLWEVTRNRN

Sequences:

>Translated_285_residues
MGNKSDSVPMKALKVSVRNAEFQIISALRTNRTKRSQEKEVFVEGTEPIKQLLAARWKVTRILYRENVPLSSWAKEVLSL
HKEAKQFEVKEELYLELSEKETPSELLITAKIKESELTIQSKKTEQQSNQNKPFYLLFDRPSDLGNFGSLLRSADAFQVD
CVFVIGHSIDVYDPKVIRSSLGTLFHTKLVFVNEFESLVRFVQMEKKRNGLVVVGSDSSGDSNLREVSIQTPILLILGNE
KKGMSVQLQSICDRIVKIPMLGVVNSLNVSCAGSILLWEVTRNRN
>Mature_284_residues
GNKSDSVPMKALKVSVRNAEFQIISALRTNRTKRSQEKEVFVEGTEPIKQLLAARWKVTRILYRENVPLSSWAKEVLSLH
KEAKQFEVKEELYLELSEKETPSELLITAKIKESELTIQSKKTEQQSNQNKPFYLLFDRPSDLGNFGSLLRSADAFQVDC
VFVIGHSIDVYDPKVIRSSLGTLFHTKLVFVNEFESLVRFVQMEKKRNGLVVVGSDSSGDSNLREVSIQTPILLILGNEK
KGMSVQLQSICDRIVKIPMLGVVNSLNVSCAGSILLWEVTRNRN

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI110825988, Length=149, Percent_Identity=31.5436241610738, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1790623, Length=178, Percent_Identity=29.2134831460674, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32232; Mature: 32100

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNKSDSVPMKALKVSVRNAEFQIISALRTNRTKRSQEKEVFVEGTEPIKQLLAARWKVT
CCCCCCCCCHHHHEEECCCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
RILYRENVPLSSWAKEVLSLHKEAKQFEVKEELYLELSEKETPSELLITAKIKESELTIQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCEEEE
SKKTEQQSNQNKPFYLLFDRPSDLGNFGSLLRSADAFQVDCVFVIGHSIDVYDPKVIRSS
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHH
LGTLFHTKLVFVNEFESLVRFVQMEKKRNGLVVVGSDSSGDSNLREVSIQTPILLILGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCC
KKGMSVQLQSICDRIVKIPMLGVVNSLNVSCAGSILLWEVTRNRN
CCCCEEEHHHHHHHHHHCCHHHHHCCCCCEECCCEEEEEEECCCC
>Mature Secondary Structure 
GNKSDSVPMKALKVSVRNAEFQIISALRTNRTKRSQEKEVFVEGTEPIKQLLAARWKVT
CCCCCCCCHHHHEEECCCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
RILYRENVPLSSWAKEVLSLHKEAKQFEVKEELYLELSEKETPSELLITAKIKESELTIQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCEEEE
SKKTEQQSNQNKPFYLLFDRPSDLGNFGSLLRSADAFQVDCVFVIGHSIDVYDPKVIRSS
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHH
LGTLFHTKLVFVNEFESLVRFVQMEKKRNGLVVVGSDSSGDSNLREVSIQTPILLILGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCC
KKGMSVQLQSICDRIVKIPMLGVVNSLNVSCAGSILLWEVTRNRN
CCCCEEEHHHHHHHHHHCCHHHHHCCCCCEECCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]