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The map label for this gene is fmt [H]

Identifier: 183221410

GI number: 183221410

Start: 2110160

End: 2110840

Strand: Reverse

Name: fmt [H]

Synonym: LEPBI_I2028

Alternate gene names: 183221410

Gene position: 2110840-2110160 (Counterclockwise)

Preceding gene: 183221411

Following gene: 183221409

Centisome position: 58.64

GC content: 38.91

Gene sequence:

>681_bases
ATGATGGAATATATTGTTGCAGCGGTGGGAAAGTGGAATCGCGAGCTATTCGAACATGAATCCAAGTTAATCCCTGGTAA
ATGGAAATTTGTAGATAGTCCGGAGAGTTTAGATCTTGTACTTGCAGACTCGAATCCAAGATACATTTTTTTCCCACATT
GGCGCTGGATAGTTCCTCCGCGGATTCTTAACCAGTATGAGTGTATCTGTTTTCATATGACAGATGTACCGTATGGAAGA
GGTGGATCTCCGTTGCAAAATTTAATCATTCGAGGCCACAAGGAAACAGTCCTAACAGCACTTCGGATGGAGAAGGGATT
GGATACAGGTCCTGTGTATATGAAACTTCCGTTAGATTTGAAAGGTTCCGCAGAAGAAATTTATACCCGAACTTCTGCTT
TGACTTGGAAGATGATTTCTGAATTTGTAACGAATGAACCGAAGGAGACTCCACAAGAAGGAGAGCCAGTCATTTTTAAG
CGCAGGAAACCAGAAGAGAGCGAATTGCCTGAAACATTGGAATTAGAAAAAATTTATGATTTTATAAGGATGTTAGATGC
TGATGGTTACCCCAATGCGCATATTAATTTTGGAAAGTACCAACTGAAATTTAACCAAGCAAAATACTTTGATGGAAAAC
TATCAGCTAACGTAGATTTTATTTTGAAAGAAGAATTATGA

Upstream 100 bases:

>100_bases
CGATTGAAGCAATTGAAGCCTTAGGAAAATGGAGAGGGGCTAATATTGGTTATTCCTTTGCAGAAGCCTTTGTTGTCGGT
AGGTTGATTCGATAATTCAA

Downstream 100 bases:

>100_bases
ATACAATTACAATTAATCAACGAAAAATTGGGAAAGAATTTCCTCCTTATATCATCGCTGAGCTTTCGGCTAATCATAAT
GGTAAGATTGAACGTGCATT

Product: putative methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MMEYIVAAVGKWNRELFEHESKLIPGKWKFVDSPESLDLVLADSNPRYIFFPHWRWIVPPRILNQYECICFHMTDVPYGR
GGSPLQNLIIRGHKETVLTALRMEKGLDTGPVYMKLPLDLKGSAEEIYTRTSALTWKMISEFVTNEPKETPQEGEPVIFK
RRKPEESELPETLELEKIYDFIRMLDADGYPNAHINFGKYQLKFNQAKYFDGKLSANVDFILKEEL

Sequences:

>Translated_226_residues
MMEYIVAAVGKWNRELFEHESKLIPGKWKFVDSPESLDLVLADSNPRYIFFPHWRWIVPPRILNQYECICFHMTDVPYGR
GGSPLQNLIIRGHKETVLTALRMEKGLDTGPVYMKLPLDLKGSAEEIYTRTSALTWKMISEFVTNEPKETPQEGEPVIFK
RRKPEESELPETLELEKIYDFIRMLDADGYPNAHINFGKYQLKFNQAKYFDGKLSANVDFILKEEL
>Mature_226_residues
MMEYIVAAVGKWNRELFEHESKLIPGKWKFVDSPESLDLVLADSNPRYIFFPHWRWIVPPRILNQYECICFHMTDVPYGR
GGSPLQNLIIRGHKETVLTALRMEKGLDTGPVYMKLPLDLKGSAEEIYTRTSALTWKMISEFVTNEPKETPQEGEPVIFK
RRKPEESELPETLELEKIYDFIRMLDADGYPNAHINFGKYQLKFNQAKYFDGKLSANVDFILKEEL

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 26365; Mature: 26365

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEYIVAAVGKWNRELFEHESKLIPGKWKFVDSPESLDLVLADSNPRYIFFPHWRWIVPP
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCCCEEEECCCEEECCH
RILNQYECICFHMTDVPYGRGGSPLQNLIIRGHKETVLTALRMEKGLDTGPVYMKLPLDL
HHHCCEEEEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
KGSAEEIYTRTSALTWKMISEFVTNEPKETPQEGEPVIFKRRKPEESELPETLELEKIYD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHCCCCCCCHHHHHH
FIRMLDADGYPNAHINFGKYQLKFNQAKYFDGKLSANVDFILKEEL
HHHHHCCCCCCCCEEECCEEEEEECCCEEECCEECCCEEEEEECCC
>Mature Secondary Structure
MMEYIVAAVGKWNRELFEHESKLIPGKWKFVDSPESLDLVLADSNPRYIFFPHWRWIVPP
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCCCEEEECCCEEECCH
RILNQYECICFHMTDVPYGRGGSPLQNLIIRGHKETVLTALRMEKGLDTGPVYMKLPLDL
HHHCCEEEEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
KGSAEEIYTRTSALTWKMISEFVTNEPKETPQEGEPVIFKRRKPEESELPETLELEKIYD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHCCCCCCCHHHHHH
FIRMLDADGYPNAHINFGKYQLKFNQAKYFDGKLSANVDFILKEEL
HHHHHCCCCCCCCEEECCEEEEEECCCEEECCEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA