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The map label for this gene is cysS [H]

Identifier: 183221111

GI number: 183221111

Start: 1797159

End: 1798616

Strand: Direct

Name: cysS [H]

Synonym: LEPBI_I1725

Alternate gene names: 183221111

Gene position: 1797159-1798616 (Clockwise)

Preceding gene: 183221110

Following gene: 183221112

Centisome position: 49.93

GC content: 35.6

Gene sequence:

>1458_bases
ATGACAACAATTCCCTTCTTCTTTCAAAATACCAAGTCTGGAAAAAAAGAGCCCTTCCAACCAAAAGATCCAAATTCTGT
TACGATTTATTCATGTGGACCAACTGTTTATAATTTTGCTCATATCGGAAACATTCGATCATTTTTGTTTGTCGATGTGC
TGAGACGTGCTTTATTACTAGGTGGGTATAAACTGAACCAATCGATGAATATCACTGACATCGATGATAAAATCATAAAA
GAATCCATCAAACAAAACGTCAGTGTAGAAGAGTTTACAAAACCTTGGACAGATGCTTTTTTTAAAGATTTGGAAACCTT
ACAAGTTCAGAAATTAGAACATTATCCCAAAGCAACTGAGTCCATTGATGATATGGTTACTCTAGTAGAAACATTACAGT
CAAATGGACTGGCCTATGAAAGAGACGGGAATGTCTATTTTTCGATCCAAAAATTCAATCAGTATGGTGAATTATCCAAG
ATTGATGTCTCAGGAATGAAATCGGGTGTCCGTTATGATGCGGATGAATATGAAAAGGATGATGTAAGGGATTTTGTTTT
ATGGAAGAACCAAAAAACAAAAGAAGAAAAATGTTGGCATACACGAATTGGAATGGGAAGACCTGGGTGGCACTTGGAAT
GTTCCGCCATGATTCGAAAAATTTATGGTACAGGTATCGATATCCATACAGGTGGAATTGACTTACTCTTTCCACATCAT
GAAAATGAATTTGCTCAATCAGTAGGTGCCTATCCAGAAGAAACATTTGTTGGAACCTGGCTTCATTGCGAACACTTGTT
AGTTGATGGTGAGAAAATGTCAAAAAGTAAAGGGAATTTTTATACCTTACGTGACATTTTAAACAAAGGTTTTGAACCTC
GCGCCATCCGTTTTCATTTGATTTCAGCTCATTACAGGAGTAAGTTAAACTTTTCCTTGGGGAAATTAGAAGAGTCGAAA
GTGGCATTAGACAGAATTCAGAATACAATCTTTCGTTTATTGGAGTTAAATCCTTCAGTGGACCTAAATACCAATGATTG
GAATCAGATTCACTTTACCGATCCAGAAATACAAACCTTGGATTCTGATTTTTTAAATGCAATAGCAGATGACTTGAATG
TTCCGAAGGCCCTGGCGACTCTTTATGAATTTGTAAGACTCGTGAACCAATCCTTGGACCAAACTAAAGAAAAAAATGCA
GATGAGTTTTTTAAACAATGTTTAGGTTTCTTTTACAAAATAAATTCTTTATTTGCAGTATTTTCGTTTGAAAAACAGAA
GGAAACATTAGATGGAATTTCAGAAGATTGGATTTTGGATCAAATCGCCAATCGAAAACTTGCGAAACAAAACAAGGATT
TTGCGACAGCTGACAATATTCGAAAAGAGTTGGAAAAAATTGGTATCCTTCTCACAGACACAAAAGAAGGAAATACAACA
TGGAAAAAAGCCCAGTAG

Upstream 100 bases:

>100_bases
GTGATAAACGAATGCAAATTTATCCAACGGAAGGAAATGAAGCAGGCAAAGAAAAACAACCACAAGCCAACCTTGAGTTT
GTAAAAGAAATTTTTGGATT

Downstream 100 bases:

>100_bases
AAATACTCTTTGGTAAACGAAATTTTTTCGAATTTTTAGAATCATTGGAACAAATGGCTCCAGAACGGGGTATCAAAACC
ATCCGGGAAGTCATTGTTAA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTTIPFFFQNTKSGKKEPFQPKDPNSVTIYSCGPTVYNFAHIGNIRSFLFVDVLRRALLLGGYKLNQSMNITDIDDKIIK
ESIKQNVSVEEFTKPWTDAFFKDLETLQVQKLEHYPKATESIDDMVTLVETLQSNGLAYERDGNVYFSIQKFNQYGELSK
IDVSGMKSGVRYDADEYEKDDVRDFVLWKNQKTKEEKCWHTRIGMGRPGWHLECSAMIRKIYGTGIDIHTGGIDLLFPHH
ENEFAQSVGAYPEETFVGTWLHCEHLLVDGEKMSKSKGNFYTLRDILNKGFEPRAIRFHLISAHYRSKLNFSLGKLEESK
VALDRIQNTIFRLLELNPSVDLNTNDWNQIHFTDPEIQTLDSDFLNAIADDLNVPKALATLYEFVRLVNQSLDQTKEKNA
DEFFKQCLGFFYKINSLFAVFSFEKQKETLDGISEDWILDQIANRKLAKQNKDFATADNIRKELEKIGILLTDTKEGNTT
WKKAQ

Sequences:

>Translated_485_residues
MTTIPFFFQNTKSGKKEPFQPKDPNSVTIYSCGPTVYNFAHIGNIRSFLFVDVLRRALLLGGYKLNQSMNITDIDDKIIK
ESIKQNVSVEEFTKPWTDAFFKDLETLQVQKLEHYPKATESIDDMVTLVETLQSNGLAYERDGNVYFSIQKFNQYGELSK
IDVSGMKSGVRYDADEYEKDDVRDFVLWKNQKTKEEKCWHTRIGMGRPGWHLECSAMIRKIYGTGIDIHTGGIDLLFPHH
ENEFAQSVGAYPEETFVGTWLHCEHLLVDGEKMSKSKGNFYTLRDILNKGFEPRAIRFHLISAHYRSKLNFSLGKLEESK
VALDRIQNTIFRLLELNPSVDLNTNDWNQIHFTDPEIQTLDSDFLNAIADDLNVPKALATLYEFVRLVNQSLDQTKEKNA
DEFFKQCLGFFYKINSLFAVFSFEKQKETLDGISEDWILDQIANRKLAKQNKDFATADNIRKELEKIGILLTDTKEGNTT
WKKAQ
>Mature_484_residues
TTIPFFFQNTKSGKKEPFQPKDPNSVTIYSCGPTVYNFAHIGNIRSFLFVDVLRRALLLGGYKLNQSMNITDIDDKIIKE
SIKQNVSVEEFTKPWTDAFFKDLETLQVQKLEHYPKATESIDDMVTLVETLQSNGLAYERDGNVYFSIQKFNQYGELSKI
DVSGMKSGVRYDADEYEKDDVRDFVLWKNQKTKEEKCWHTRIGMGRPGWHLECSAMIRKIYGTGIDIHTGGIDLLFPHHE
NEFAQSVGAYPEETFVGTWLHCEHLLVDGEKMSKSKGNFYTLRDILNKGFEPRAIRFHLISAHYRSKLNFSLGKLEESKV
ALDRIQNTIFRLLELNPSVDLNTNDWNQIHFTDPEIQTLDSDFLNAIADDLNVPKALATLYEFVRLVNQSLDQTKEKNAD
EFFKQCLGFFYKINSLFAVFSFEKQKETLDGISEDWILDQIANRKLAKQNKDFATADNIRKELEKIGILLTDTKEGNTTW
KKAQ

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=510, Percent_Identity=29.0196078431373, Blast_Score=215, Evalue=8e-56,
Organism=Homo sapiens, GI303304987, Length=273, Percent_Identity=34.0659340659341, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI21269877, Length=273, Percent_Identity=34.0659340659341, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI62240992, Length=273, Percent_Identity=34.0659340659341, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI10835051, Length=273, Percent_Identity=34.0659340659341, Blast_Score=152, Evalue=9e-37,
Organism=Escherichia coli, GI1786737, Length=486, Percent_Identity=36.2139917695473, Blast_Score=271, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI17509795, Length=445, Percent_Identity=27.4157303370787, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17509797, Length=445, Percent_Identity=27.4157303370787, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6324082, Length=349, Percent_Identity=31.5186246418338, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI19922218, Length=500, Percent_Identity=28.8, Blast_Score=208, Evalue=8e-54,
Organism=Drosophila melanogaster, GI19922364, Length=385, Percent_Identity=28.5714285714286, Blast_Score=158, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 55970; Mature: 55839

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIPFFFQNTKSGKKEPFQPKDPNSVTIYSCGPTVYNFAHIGNIRSFLFVDVLRRALLL
CCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GGYKLNQSMNITDIDDKIIKESIKQNVSVEEFTKPWTDAFFKDLETLQVQKLEHYPKATE
CCEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHH
SIDDMVTLVETLQSNGLAYERDGNVYFSIQKFNQYGELSKIDVSGMKSGVRYDADEYEKD
HHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCCEEEHHHHHCCCCCCCHHCCHH
DVRDFVLWKNQKTKEEKCWHTRIGMGRPGWHLECSAMIRKIYGTGIDIHTGGIDLLFPHH
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCCEEECCCEEEEECCC
ENEFAQSVGAYPEETFVGTWLHCEHLLVDGEKMSKSKGNFYTLRDILNKGFEPRAIRFHL
CHHHHHHHCCCCCHHHEEHHHHHHHHHCCCHHHHCCCCCEEEHHHHHHCCCCCCEEEEEE
ISAHYRSKLNFSLGKLEESKVALDRIQNTIFRLLELNPSVDLNTNDWNQIHFTDPEIQTL
EHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHH
DSDFLNAIADDLNVPKALATLYEFVRLVNQSLDQTKEKNADEFFKQCLGFFYKINSLFAV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FSFEKQKETLDGISEDWILDQIANRKLAKQNKDFATADNIRKELEKIGILLTDTKEGNTT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCCC
WKKAQ
CCCCC
>Mature Secondary Structure 
TTIPFFFQNTKSGKKEPFQPKDPNSVTIYSCGPTVYNFAHIGNIRSFLFVDVLRRALLL
CCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GGYKLNQSMNITDIDDKIIKESIKQNVSVEEFTKPWTDAFFKDLETLQVQKLEHYPKATE
CCEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHH
SIDDMVTLVETLQSNGLAYERDGNVYFSIQKFNQYGELSKIDVSGMKSGVRYDADEYEKD
HHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCCEEEHHHHHCCCCCCCHHCCHH
DVRDFVLWKNQKTKEEKCWHTRIGMGRPGWHLECSAMIRKIYGTGIDIHTGGIDLLFPHH
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCCEEECCCEEEEECCC
ENEFAQSVGAYPEETFVGTWLHCEHLLVDGEKMSKSKGNFYTLRDILNKGFEPRAIRFHL
CHHHHHHHCCCCCHHHEEHHHHHHHHHCCCHHHHCCCCCEEEHHHHHHCCCCCCEEEEEE
ISAHYRSKLNFSLGKLEESKVALDRIQNTIFRLLELNPSVDLNTNDWNQIHFTDPEIQTL
EHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHH
DSDFLNAIADDLNVPKALATLYEFVRLVNQSLDQTKEKNADEFFKQCLGFFYKINSLFAV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FSFEKQKETLDGISEDWILDQIANRKLAKQNKDFATADNIRKELEKIGILLTDTKEGNTT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCCC
WKKAQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA