BacMap

Definition	Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence.
Accession	NC_010602
Length	3,599,677

Click here to switch to the map view.

The map label for this gene is yusZ [H]

Identifier: 183220932

GI number: 183220932

Start: 1610502

End: 1611305

Strand: Reverse

Name: yusZ [H]

Synonym: LEPBI_I1545

Alternate gene names: 183220932

Gene position: 1611305-1610502 (Counterclockwise)

Preceding gene: 183220934

Following gene: 183220931

Centisome position: 44.76

GC content: 35.45

Gene sequence:

>804_bases
ATGAAACAAACAATTCTCATCACAGGCGCTTCTTCAGGGATTGGACTTTTAATCGCAAACAAACTCCATAACGAGGGACA
TACTGTGATTGGTACTAGTCGCAATCCGAAAGCCCACGCTTCCAAATTCCCGTTTCCATTGGTGGAATTAGACCTGAACG
AAGACCAATCCATAGAATCGTTTGGAAAAAGGTTATTCAGTGAAATCCCAAAATTAGATGTTCTTATCAATAACGCTGGT
TACTTGGTATCGGGACTTGCAGAAGAAACTTCGATTGGATTAGGGAAAAAACAATTTGAAACAAATTTTTGGGGAACAAT
CAAACTCACCAATCAATTTCTTCCCTATTTTCGCAAACAACGTTCTGGAAAAATCATTACAGTTGGATCGTTTTTAGGAT
TGATTGGATTACCAACTGTCGGCTATTATTCGGCTTCTAAACATGCGTTGGAAGGTTATTTTAAGGCATTACGGTTCGAA
GTAAAAGATTTTAACATTGATGTATGTATGGTAGAACCGATGAATTTCAAAACCAGTATAGGAGAAAATTCAGTTCGTTC
TGATTTAAAAATCGATGATTATGATTTACTCCGAAAACAAACAGACAATTTTTCAAAACAACAATTTGAGAATTCTCCAA
CGCCAGAACCTGTTGTGGACATGATTCTAAAAGTGGTAAGTGATAAGAATCCGAAATTCAATCATCCAGTCGGAAAAGGA
GTATCCTTTATCCTTTTTATGCAACAATATGTTTATAAAGTTTTTGAAAATTCAATTCTAAAACAAGTTCATAAGGCATT
CTAA

Upstream 100 bases:

>100_bases
CACTTGCATTTTGAAAGTATCTTTCGTCCTGCATACTTGTAAATTGCAAGTGATATAGTCATAGAGAACCAATTACGGTA
AAAATAGCAAGGATATTTAT

Downstream 100 bases:

>100_bases
AAAGGAATCAATCAGGTAAATTAAATGAAAGCATTCACCATCAACCGATACAATAAACACCAAAACCTGCAACTCACAGA
AGTATCTGATCCCATCTTAA

Product: putative short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKQTILITGASSGIGLLIANKLHNEGHTVIGTSRNPKAHASKFPFPLVELDLNEDQSIESFGKRLFSEIPKLDVLINNAG
YLVSGLAEETSIGLGKKQFETNFWGTIKLTNQFLPYFRKQRSGKIITVGSFLGLIGLPTVGYYSASKHALEGYFKALRFE
VKDFNIDVCMVEPMNFKTSIGENSVRSDLKIDDYDLLRKQTDNFSKQQFENSPTPEPVVDMILKVVSDKNPKFNHPVGKG
VSFILFMQQYVYKVFENSILKQVHKAF

Sequences:

>Translated_267_residues
MKQTILITGASSGIGLLIANKLHNEGHTVIGTSRNPKAHASKFPFPLVELDLNEDQSIESFGKRLFSEIPKLDVLINNAG
YLVSGLAEETSIGLGKKQFETNFWGTIKLTNQFLPYFRKQRSGKIITVGSFLGLIGLPTVGYYSASKHALEGYFKALRFE
VKDFNIDVCMVEPMNFKTSIGENSVRSDLKIDDYDLLRKQTDNFSKQQFENSPTPEPVVDMILKVVSDKNPKFNHPVGKG
VSFILFMQQYVYKVFENSILKQVHKAF
>Mature_267_residues
MKQTILITGASSGIGLLIANKLHNEGHTVIGTSRNPKAHASKFPFPLVELDLNEDQSIESFGKRLFSEIPKLDVLINNAG
YLVSGLAEETSIGLGKKQFETNFWGTIKLTNQFLPYFRKQRSGKIITVGSFLGLIGLPTVGYYSASKHALEGYFKALRFE
VKDFNIDVCMVEPMNFKTSIGENSVRSDLKIDDYDLLRKQTDNFSKQQFENSPTPEPVVDMILKVVSDKNPKFNHPVGKG
VSFILFMQQYVYKVFENSILKQVHKAF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=30.6532663316583, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI7657478, Length=254, Percent_Identity=29.1338582677165, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=32.8282828282828, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI157739938, Length=184, Percent_Identity=33.1521739130435, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI223718074, Length=254, Percent_Identity=28.3464566929134, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI119392083, Length=283, Percent_Identity=27.208480565371, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI44680136, Length=192, Percent_Identity=30.7291666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI44680133, Length=192, Percent_Identity=30.7291666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI17738292, Length=192, Percent_Identity=30.7291666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=27.807486631016, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI22507405, Length=255, Percent_Identity=24.7058823529412, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI19743808, Length=184, Percent_Identity=29.8913043478261, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI150247226, Length=202, Percent_Identity=30.1980198019802, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40548397, Length=192, Percent_Identity=31.25, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI214010158, Length=192, Percent_Identity=31.25, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI214010156, Length=192, Percent_Identity=31.25, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI22758144, Length=192, Percent_Identity=31.25, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI32455239, Length=190, Percent_Identity=30.5263157894737, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI5031765, Length=190, Percent_Identity=30.5263157894737, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI142976729, Length=174, Percent_Identity=31.6091954022989, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI4504503, Length=276, Percent_Identity=23.9130434782609, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1786701, Length=242, Percent_Identity=30.9917355371901, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787335, Length=173, Percent_Identity=32.3699421965318, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786812, Length=231, Percent_Identity=26.8398268398268, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=28.4090909090909, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=254, Percent_Identity=30.3149606299213, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71997402, Length=243, Percent_Identity=30.0411522633745, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193210355, Length=218, Percent_Identity=28.8990825688073, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17557780, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563809, Length=279, Percent_Identity=26.5232974910394, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17507613, Length=279, Percent_Identity=26.5232974910394, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.1794871794872, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534660, Length=188, Percent_Identity=29.7872340425532, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=185, Percent_Identity=28.1081081081081, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=188, Percent_Identity=28.1914893617021, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=250, Percent_Identity=26.4, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=225, Percent_Identity=28, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=32.3076923076923, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24651139, Length=248, Percent_Identity=31.4516129032258, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21356301, Length=188, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007236, Length=208, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=30.4812834224599, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007238, Length=182, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=178, Percent_Identity=26.4044943820225, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=28.7234042553192, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=191, Percent_Identity=31.413612565445, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24580925, Length=187, Percent_Identity=25.668449197861, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641232, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=180, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30022; Mature: 30022

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00061 ADH_SHORT ; PS00605 ATPASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTILITGASSGIGLLIANKLHNEGHTVIGTSRNPKAHASKFPFPLVELDLNEDQSIES
CCCEEEEEECCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHH
FGKRLFSEIPKLDVLINNAGYLVSGLAEETSIGLGKKQFETNFWGTIKLTNQFLPYFRKQ
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCCEEEEEEHHHHHHHHHHH
RSGKIITVGSFLGLIGLPTVGYYSASKHALEGYFKALRFEVKDFNIDVCMVEPMNFKTSI
CCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEEECCEEEEEECCCCCCCCC
GENSVRSDLKIDDYDLLRKQTDNFSKQQFENSPTPEPVVDMILKVVSDKNPKFNHPVGKG
CCCHHHCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCH
VSFILFMQQYVYKVFENSILKQVHKAF
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQTILITGASSGIGLLIANKLHNEGHTVIGTSRNPKAHASKFPFPLVELDLNEDQSIES
CCCEEEEEECCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHH
FGKRLFSEIPKLDVLINNAGYLVSGLAEETSIGLGKKQFETNFWGTIKLTNQFLPYFRKQ
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCCEEEEEEHHHHHHHHHHH
RSGKIITVGSFLGLIGLPTVGYYSASKHALEGYFKALRFEVKDFNIDVCMVEPMNFKTSI
CCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEEECCEEEEEECCCCCCCCC
GENSVRSDLKIDDYDLLRKQTDNFSKQQFENSPTPEPVVDMILKVVSDKNPKFNHPVGKG
CCCHHHCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCH
VSFILFMQQYVYKVFENSILKQVHKAF
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]