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The map label for this gene is gclK [H]

Identifier: 183220883

GI number: 183220883

Start: 1556788

End: 1557684

Strand: Reverse

Name: gclK [H]

Synonym: LEPBI_I1496

Alternate gene names: 183220883

Gene position: 1557684-1556788 (Counterclockwise)

Preceding gene: 183220884

Following gene: 183220882

Centisome position: 43.27

GC content: 41.14

Gene sequence:

>897_bases
TTGAGACAAGCGATTGGTGTTGATATTGGTGGAGGAAGCATCCGCGTTTCTCTTTTTGATGAAAATGGAAGTGAACTAGA
CTCCCATCACACCAAAACCCCTGAACACTTAGACAATGATTCCTTTTTAGAAGTACTGGTCGAAAGCATTCGCCCACTTG
TAAAGAATATCATTGGAATTGGTGTTGGTTCCCCTGGCCCTCTCAATAACGAAACGGGCGTTATGCTGACAAGTGCCAAT
ATGGCAGGTCTTAAGAACTTACCCATCAAATCAGTTTTACAAAAAGAATTTTCACTTCCAGTATTCTATGAAAACGACGC
CAACTGTGCTGCATTAGGTGAAGCTATCTTTGGAACGTATAAAAACACCGAATCACAATTAATTTTGACATTAGGAACAG
GGATTGGTGGAGGGTTTGTCAAACAAGGTAAACTTTATACGGGATACCTTGGGAATGGAATCGAAATTGGCCATACCACT
TCTGTCATCGGGGGCGCCTTGTGCGGATGCGGAGTTCACGGTTGTGTGGAGAGTTATTTTTCCACAAAAGGATTTTTAAA
CCGTTATTTTGAAAAAACCAATACCAAACTCCCCAATGCAGAAGCCTTTTTTTCACTCGTTCGATCGAATGATTCAGAAT
CAAAATCCATTTTGGAATTTGGAACCAAAGCTTTAGCACACGCAGTTCGTAATGCGATCCAATTACTCAACCCAGAAGCG
GTCATTTTTGTGGGTGGGATCACCAAGTCCTATGATTTGTTTGGTGCACTTTTAGAAAAAGAAATTCGATCTACAATCTT
TTCTGTATTAAACGATCGATTATTACTTGGGCCTGGGGGCAATATATCAGGAACTCTGGGTGCCGCCTCACTTGTTTTTG
TTAAGGAGAAAAACTGA

Upstream 100 bases:

>100_bases
ATCCTTGTCACCCATGACATGAAACTCGCCTTTGATGCCCAAACCGTTTATGAAATGAAAAACGGAAGGTTCGAACAAGT
GATCAAAGGAGAGTGAAGTT

Downstream 100 bases:

>100_bases
TATGGAAGACTGTATTTTTTGTAAGATCATTCGCGGTGAAATACCTGCCAAAAAAGAATACGAAACTGATTCTATTTTTG
TATTCCATGACATCACTCCA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MRQAIGVDIGGGSIRVSLFDENGSELDSHHTKTPEHLDNDSFLEVLVESIRPLVKNIIGIGVGSPGPLNNETGVMLTSAN
MAGLKNLPIKSVLQKEFSLPVFYENDANCAALGEAIFGTYKNTESQLILTLGTGIGGGFVKQGKLYTGYLGNGIEIGHTT
SVIGGALCGCGVHGCVESYFSTKGFLNRYFEKTNTKLPNAEAFFSLVRSNDSESKSILEFGTKALAHAVRNAIQLLNPEA
VIFVGGITKSYDLFGALLEKEIRSTIFSVLNDRLLLGPGGNISGTLGAASLVFVKEKN

Sequences:

>Translated_298_residues
MRQAIGVDIGGGSIRVSLFDENGSELDSHHTKTPEHLDNDSFLEVLVESIRPLVKNIIGIGVGSPGPLNNETGVMLTSAN
MAGLKNLPIKSVLQKEFSLPVFYENDANCAALGEAIFGTYKNTESQLILTLGTGIGGGFVKQGKLYTGYLGNGIEIGHTT
SVIGGALCGCGVHGCVESYFSTKGFLNRYFEKTNTKLPNAEAFFSLVRSNDSESKSILEFGTKALAHAVRNAIQLLNPEA
VIFVGGITKSYDLFGALLEKEIRSTIFSVLNDRLLLGPGGNISGTLGAASLVFVKEKN
>Mature_298_residues
MRQAIGVDIGGGSIRVSLFDENGSELDSHHTKTPEHLDNDSFLEVLVESIRPLVKNIIGIGVGSPGPLNNETGVMLTSAN
MAGLKNLPIKSVLQKEFSLPVFYENDANCAALGEAIFGTYKNTESQLILTLGTGIGGGFVKQGKLYTGYLGNGIEIGHTT
SVIGGALCGCGVHGCVESYFSTKGFLNRYFEKTNTKLPNAEAFFSLVRSNDSESKSILEFGTKALAHAVRNAIQLLNPEA
VIFVGGITKSYDLFGALLEKEIRSTIFSVLNDRLLLGPGGNISGTLGAASLVFVKEKN

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=310, Percent_Identity=30, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI298566325, Length=310, Percent_Identity=30, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4885285, Length=310, Percent_Identity=30, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI190014632, Length=310, Percent_Identity=30, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1787363, Length=302, Percent_Identity=29.4701986754967, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87081733, Length=275, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786891, Length=262, Percent_Identity=23.6641221374046, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787878, Length=219, Percent_Identity=20.5479452054795, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082230, Length=259, Percent_Identity=27.4131274131274, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790522, Length=303, Percent_Identity=25.4125412541254, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 31665; Mature: 31665

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQAIGVDIGGGSIRVSLFDENGSELDSHHTKTPEHLDNDSFLEVLVESIRPLVKNIIGI
CCCEEEEEECCCEEEEEEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GVGSPGPLNNETGVMLTSANMAGLKNLPIKSVLQKEFSLPVFYENDANCAALGEAIFGTY
CCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHC
KNTESQLILTLGTGIGGGFVKQGKLYTGYLGNGIEIGHTTSVIGGALCGCGVHGCVESYF
CCCCCEEEEEEECCCCCCCEECCCEEEEECCCCEEECCHHHHHHHHHHHCCHHHHHHHHH
STKGFLNRYFEKTNTKLPNAEAFFSLVRSNDSESKSILEFGTKALAHAVRNAIQLLNPEA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VIFVGGITKSYDLFGALLEKEIRSTIFSVLNDRLLLGPGGNISGTLGAASLVFVKEKN
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MRQAIGVDIGGGSIRVSLFDENGSELDSHHTKTPEHLDNDSFLEVLVESIRPLVKNIIGI
CCCEEEEEECCCEEEEEEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GVGSPGPLNNETGVMLTSANMAGLKNLPIKSVLQKEFSLPVFYENDANCAALGEAIFGTY
CCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHC
KNTESQLILTLGTGIGGGFVKQGKLYTGYLGNGIEIGHTTSVIGGALCGCGVHGCVESYF
CCCCCEEEEEEECCCCCCCEECCCEEEEECCCCEEECCHHHHHHHHHHHCCHHHHHHHHH
STKGFLNRYFEKTNTKLPNAEAFFSLVRSNDSESKSILEFGTKALAHAVRNAIQLLNPEA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VIFVGGITKSYDLFGALLEKEIRSTIFSVLNDRLLLGPGGNISGTLGAASLVFVKEKN
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]