| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is mrcA [H]
Identifier: 183220820
GI number: 183220820
Start: 1495345
End: 1497897
Strand: Reverse
Name: mrcA [H]
Synonym: LEPBI_I1432
Alternate gene names: 183220820
Gene position: 1497897-1495345 (Counterclockwise)
Preceding gene: 183220821
Following gene: 183220819
Centisome position: 41.61
GC content: 44.38
Gene sequence:
>2553_bases ATGAAACAAGAACCCGTTGGGCTCTTTGAAAAGTATTTTATCATTTGGTTTCGGATCGTTACAGAAAGGATTTGGACTGG AGACAAAAAAGTTCGGAACACTTTCCTTGTCATTTTAGGATTTGGTATCCTAAATGGTTTTTTACTCACAGGCTCTGTGA AAGATTTTTTTCGATTGGGGGAAGCGGCGGTTTACGACATCCCTTCCACCTTATACGGATTAAACGACAAAGGGGAATAC GAACCCATCGCTGAATATTATAAATTCTCTCGCATCCCAGTTAAGTTAGAACAACTCAAATCCGAAGAAACCAATTATTC CACTGACAACCGTCACAAACTCATCCAATGTTTTTTATCAACAGAGGATAATTCTTTTTATTCCCATAATGGAATTGATC TCAAAGGAATCGCTCGTGCCTTTGTGGTGAACCTCATGGCAGGTCGTGTCAAAGAAGGTGCCTCCACCATCACACAACAA GTCGCAAGGCTTAAGTTTTTATCCATCGAACGTTCCATTGCAAGGAAAGCTCGTGAAGCATGGCTTGCCATATTACTCGA ACTCGTTTACCCAAAAGACAAAATCTTAGAAGTGTATTTGAACGAAATCCCTCTTGGGCATGGAACCATTGGTGTGGGTG CTGCGTCTCGGTTTTACTTTCGAAAGGAAGTACAAGATGTCACCTGGGGGGAAGCGGCGATTTTAGCAAGCCTCACCACA AGGCCCACTCAGTTTAGTCCCATTGTGAATCCCGTTTCCAGTATGAACAAAGTACGAGTCGTCTTTCGTAAGTTAGTTGA AAATGGAAGGATGACAGTGGCAGATGCCGAAAAAGAATTTGGAATTTTAGAGGAATACTATACAAACTTAAATCGTTCCC CAAATGATTCTGCCTTTTCTGACAGGTTAAACAAATTTCCCTATGTCACAGAATACATCCGAAAAAACCTAATCCGTTCC ATCGGTTCCAGTCGTTTGTACAATGGTGGACTCAAAATTTATTCCACCATCCAAATCCGCCACCAAGAAGAAGCAGAAAA AGCACTCCTCCCCGCCTTACAAAGGCAAACGATTGAGTCAAACCAACGGGCATTTCGGAACATTGATGCCTTTGATGATT TGTATGGCAGTGGGTATTCCCTCATTGCCGATTTAAACGATTTACCAGAATTTAAATTTAAAATATCAAAAATCGAACGA ACCTTTTCTTCCGCCTACCAAGAAGACATACGTGATGAGTTTTCTGCCTTAAACTTACTGACGGGAGACGATTATCTTGG TGACACACTCGATAAAAACTTCACCTCCCAAAGTACAAAAGACCACCTTCTCCCCGTAGAAGGATCGCTCATCGCCATTC GCCCTGAAACAGGTTACATCACAGCCCTCGTGGGTGGATCGGGCTTTCGTTCTGATAACCAACAGATCCGACCCTTCCAA GCCTTTCGCCAACCAGGTTCTGCATTCAAACCCATTTTGTACGCGGCGGCCATGGACCATTCTGGGAAAAACCCAGACCC TGAAAAAAACGTAACACCTGCAACACTTTTTGCCGACTCACCCCTCCAGTATTTGATGGAAGATGGAGACGAATGGGCAC CAGAAAACTATAGTAGCGAATACTCAGGATTCATTTTGTTACGTAAGGCCTTGGAACAATCCAAAAACTCTGTGGCTGTG CGAGTCCTCGAACAAGTGGGGCTTTCCAATTTGATGGAGAGCCTACGTGGGTTATTACAATTACAAGGTCGCGACATCCC TTACAACTTCAGTGTTTCCTTGGGTTCCTTTGAACTCACACCTTACGAACTCACTCGCGCCTATGCGGCCCTTGCTTCGG GCGGAAAAACCGTAAATCCCATCTCGGTTTTGTATGTGGAAGACAACGCGGGTAAGGTCATCAAAGACTTTCGAAAGGAC TACGAAGATGTGGAACGTAAACAAATCATCTCCAAGGAAGCGGCCTTTCTCATCACTTCCATGATGAAGGATGTGGTGGA AGAAGGAACAGGACGAGGTGTTCTCTCCTATGGACTGAACCGTAAGGCCTATGGAAAAACGGGCACCACCAATAATTTTC GAGATGCATGGTTTGTAGGTTACACCCCTGAACTTGTCACCTCAGTATGGTTTGGTTATGATGTGGGAACCATCTCTCTT GGCCGAGGCATGACAGGAGGGAAACTTTCTGCCCCTGTTTGGGGTCGGTTTATGGCACGAGCCCTCGAAAAAGAGCCACC AAAAGAATTCCCTTGGTTATCTGAGGTAAAAATCTCCAAACGAACGGTCTGCCGTATGTCGGGCAAACTCCCCAGTGGGC AATGCCATGATCTTTTAGAAGAATACTTCATCCCACAAACGGTCCCAAAAGACGTTTGTAACGACCATGGTTCGGCTTGG AATGTAGTGGAAACAAAAACACAAAACCCAGTCACACAAAAACCAGCAGAACCTAAAAAACAAGACACAAAAGTAGAGAA AAAACCCTCCGAGTCCAAACCGCCAAAACGAAAAAAATCGGTCTTTAGCGGAGATGAGGAAATTGACTACTAA
Upstream 100 bases:
>100_bases TGGTGGTTATAATTTGGATACGGGCCTTCGATATCATGGCATTGACCACATGAAGGAATTTTCTCCACTCGTTTAGTAGG AATTTGAAAAAGGAAATTGT
Downstream 100 bases:
>100_bases AAAGGCTTGTCAGATAGACCGAAAATTTTGATTCTCACAGAAGGGGAAAAGGAGCAGGAATGGCAATAGGTAAGGATTCC ATCAACAGCGTTATCGGACC
Product: putative penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 850; Mature: 850
Protein sequence:
>850_residues MKQEPVGLFEKYFIIWFRIVTERIWTGDKKVRNTFLVILGFGILNGFLLTGSVKDFFRLGEAAVYDIPSTLYGLNDKGEY EPIAEYYKFSRIPVKLEQLKSEETNYSTDNRHKLIQCFLSTEDNSFYSHNGIDLKGIARAFVVNLMAGRVKEGASTITQQ VARLKFLSIERSIARKAREAWLAILLELVYPKDKILEVYLNEIPLGHGTIGVGAASRFYFRKEVQDVTWGEAAILASLTT RPTQFSPIVNPVSSMNKVRVVFRKLVENGRMTVADAEKEFGILEEYYTNLNRSPNDSAFSDRLNKFPYVTEYIRKNLIRS IGSSRLYNGGLKIYSTIQIRHQEEAEKALLPALQRQTIESNQRAFRNIDAFDDLYGSGYSLIADLNDLPEFKFKISKIER TFSSAYQEDIRDEFSALNLLTGDDYLGDTLDKNFTSQSTKDHLLPVEGSLIAIRPETGYITALVGGSGFRSDNQQIRPFQ AFRQPGSAFKPILYAAAMDHSGKNPDPEKNVTPATLFADSPLQYLMEDGDEWAPENYSSEYSGFILLRKALEQSKNSVAV RVLEQVGLSNLMESLRGLLQLQGRDIPYNFSVSLGSFELTPYELTRAYAALASGGKTVNPISVLYVEDNAGKVIKDFRKD YEDVERKQIISKEAAFLITSMMKDVVEEGTGRGVLSYGLNRKAYGKTGTTNNFRDAWFVGYTPELVTSVWFGYDVGTISL GRGMTGGKLSAPVWGRFMARALEKEPPKEFPWLSEVKISKRTVCRMSGKLPSGQCHDLLEEYFIPQTVPKDVCNDHGSAW NVVETKTQNPVTQKPAEPKKQDTKVEKKPSESKPPKRKKSVFSGDEEIDY
Sequences:
>Translated_850_residues MKQEPVGLFEKYFIIWFRIVTERIWTGDKKVRNTFLVILGFGILNGFLLTGSVKDFFRLGEAAVYDIPSTLYGLNDKGEY EPIAEYYKFSRIPVKLEQLKSEETNYSTDNRHKLIQCFLSTEDNSFYSHNGIDLKGIARAFVVNLMAGRVKEGASTITQQ VARLKFLSIERSIARKAREAWLAILLELVYPKDKILEVYLNEIPLGHGTIGVGAASRFYFRKEVQDVTWGEAAILASLTT RPTQFSPIVNPVSSMNKVRVVFRKLVENGRMTVADAEKEFGILEEYYTNLNRSPNDSAFSDRLNKFPYVTEYIRKNLIRS IGSSRLYNGGLKIYSTIQIRHQEEAEKALLPALQRQTIESNQRAFRNIDAFDDLYGSGYSLIADLNDLPEFKFKISKIER TFSSAYQEDIRDEFSALNLLTGDDYLGDTLDKNFTSQSTKDHLLPVEGSLIAIRPETGYITALVGGSGFRSDNQQIRPFQ AFRQPGSAFKPILYAAAMDHSGKNPDPEKNVTPATLFADSPLQYLMEDGDEWAPENYSSEYSGFILLRKALEQSKNSVAV RVLEQVGLSNLMESLRGLLQLQGRDIPYNFSVSLGSFELTPYELTRAYAALASGGKTVNPISVLYVEDNAGKVIKDFRKD YEDVERKQIISKEAAFLITSMMKDVVEEGTGRGVLSYGLNRKAYGKTGTTNNFRDAWFVGYTPELVTSVWFGYDVGTISL GRGMTGGKLSAPVWGRFMARALEKEPPKEFPWLSEVKISKRTVCRMSGKLPSGQCHDLLEEYFIPQTVPKDVCNDHGSAW NVVETKTQNPVTQKPAEPKKQDTKVEKKPSESKPPKRKKSVFSGDEEIDY >Mature_850_residues MKQEPVGLFEKYFIIWFRIVTERIWTGDKKVRNTFLVILGFGILNGFLLTGSVKDFFRLGEAAVYDIPSTLYGLNDKGEY EPIAEYYKFSRIPVKLEQLKSEETNYSTDNRHKLIQCFLSTEDNSFYSHNGIDLKGIARAFVVNLMAGRVKEGASTITQQ VARLKFLSIERSIARKAREAWLAILLELVYPKDKILEVYLNEIPLGHGTIGVGAASRFYFRKEVQDVTWGEAAILASLTT RPTQFSPIVNPVSSMNKVRVVFRKLVENGRMTVADAEKEFGILEEYYTNLNRSPNDSAFSDRLNKFPYVTEYIRKNLIRS IGSSRLYNGGLKIYSTIQIRHQEEAEKALLPALQRQTIESNQRAFRNIDAFDDLYGSGYSLIADLNDLPEFKFKISKIER TFSSAYQEDIRDEFSALNLLTGDDYLGDTLDKNFTSQSTKDHLLPVEGSLIAIRPETGYITALVGGSGFRSDNQQIRPFQ AFRQPGSAFKPILYAAAMDHSGKNPDPEKNVTPATLFADSPLQYLMEDGDEWAPENYSSEYSGFILLRKALEQSKNSVAV RVLEQVGLSNLMESLRGLLQLQGRDIPYNFSVSLGSFELTPYELTRAYAALASGGKTVNPISVLYVEDNAGKVIKDFRKD YEDVERKQIISKEAAFLITSMMKDVVEEGTGRGVLSYGLNRKAYGKTGTTNNFRDAWFVGYTPELVTSVWFGYDVGTISL GRGMTGGKLSAPVWGRFMARALEKEPPKEFPWLSEVKISKRTVCRMSGKLPSGQCHDLLEEYFIPQTVPKDVCNDHGSAW NVVETKTQNPVTQKPAEPKKQDTKVEKKPSESKPPKRKKSVFSGDEEIDY
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=871, Percent_Identity=30.4247990815155, Blast_Score=298, Evalue=9e-82, Organism=Escherichia coli, GI1786343, Length=251, Percent_Identity=33.0677290836653, Blast_Score=124, Evalue=3e-29, Organism=Escherichia coli, GI1788867, Length=139, Percent_Identity=36.6906474820144, Blast_Score=90, Evalue=6e-19, Organism=Escherichia coli, GI1789601, Length=129, Percent_Identity=40.3100775193798, Blast_Score=85, Evalue=2e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 95895; Mature: 95895
Theoretical pI: Translated: 8.18; Mature: 8.18
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKQEPVGLFEKYFIIWFRIVTERIWTGDKKVRNTFLVILGFGILNGFLLTGSVKDFFRLG CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEECCHHHHHHCC EAAVYDIPSTLYGLNDKGEYEPIAEYYKFSRIPVKLEQLKSEETNYSTDNRHKLIQCFLS CHHEEECCHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHC TEDNSFYSHNGIDLKGIARAFVVNLMAGRVKEGASTITQQVARLKFLSIERSIARKAREA CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH WLAILLELVYPKDKILEVYLNEIPLGHGTIGVGAASRFYFRKEVQDVTWGEAAILASLTT HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCC RPTQFSPIVNPVSSMNKVRVVFRKLVENGRMTVADAEKEFGILEEYYTNLNRSPNDSAFS CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHH DRLNKFPYVTEYIRKNLIRSIGSSRLYNGGLKIYSTIQIRHQEEAEKALLPALQRQTIES HHHHCCCHHHHHHHHHHHHHHCCCCEECCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHH NQRAFRNIDAFDDLYGSGYSLIADLNDLPEFKFKISKIERTFSSAYQEDIRDEFSALNLL HHHHHHCCCHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE TGDDYLGDTLDKNFTSQSTKDHLLPVEGSLIAIRPETGYITALVGGSGFRSDNQQIRPFQ CCCCHHCCHHHCCCCCCCCCCCEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCCCHHH AFRQPGSAFKPILYAAAMDHSGKNPDPEKNVTPATLFADSPLQYLMEDGDEWAPENYSSE HHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCC YSGFILLRKALEQSKNSVAVRVLEQVGLSNLMESLRGLLQLQGRDIPYNFSVSLGSFELT HHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECC PYELTRAYAALASGGKTVNPISVLYVEDNAGKVIKDFRKDYEDVERKQIISKEAAFLITS HHHHHHHHHHHHCCCCEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH MMKDVVEEGTGRGVLSYGLNRKAYGKTGTTNNFRDAWFVGYTPELVTSVWFGYDVGTISL HHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCEEEE GRGMTGGKLSAPVWGRFMARALEKEPPKEFPWLSEVKISKRTVCRMSGKLPSGQCHDLLE CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH EYFIPQTVPKDVCNDHGSAWNVVETKTQNPVTQKPAEPKKQDTKVEKKPSESKPPKRKKS HHCCCCCCCHHHHCCCCCCCCEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHH VFSGDEEIDY HCCCCCCCCC >Mature Secondary Structure MKQEPVGLFEKYFIIWFRIVTERIWTGDKKVRNTFLVILGFGILNGFLLTGSVKDFFRLG CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEECCHHHHHHCC EAAVYDIPSTLYGLNDKGEYEPIAEYYKFSRIPVKLEQLKSEETNYSTDNRHKLIQCFLS CHHEEECCHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHC TEDNSFYSHNGIDLKGIARAFVVNLMAGRVKEGASTITQQVARLKFLSIERSIARKAREA CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH WLAILLELVYPKDKILEVYLNEIPLGHGTIGVGAASRFYFRKEVQDVTWGEAAILASLTT HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCC RPTQFSPIVNPVSSMNKVRVVFRKLVENGRMTVADAEKEFGILEEYYTNLNRSPNDSAFS CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHH DRLNKFPYVTEYIRKNLIRSIGSSRLYNGGLKIYSTIQIRHQEEAEKALLPALQRQTIES HHHHCCCHHHHHHHHHHHHHHCCCCEECCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHH NQRAFRNIDAFDDLYGSGYSLIADLNDLPEFKFKISKIERTFSSAYQEDIRDEFSALNLL HHHHHHCCCHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE TGDDYLGDTLDKNFTSQSTKDHLLPVEGSLIAIRPETGYITALVGGSGFRSDNQQIRPFQ CCCCHHCCHHHCCCCCCCCCCCEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCCCHHH AFRQPGSAFKPILYAAAMDHSGKNPDPEKNVTPATLFADSPLQYLMEDGDEWAPENYSSE HHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCC YSGFILLRKALEQSKNSVAVRVLEQVGLSNLMESLRGLLQLQGRDIPYNFSVSLGSFELT HHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECC PYELTRAYAALASGGKTVNPISVLYVEDNAGKVIKDFRKDYEDVERKQIISKEAAFLITS HHHHHHHHHHHHCCCCEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH MMKDVVEEGTGRGVLSYGLNRKAYGKTGTTNNFRDAWFVGYTPELVTSVWFGYDVGTISL HHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCEEEE GRGMTGGKLSAPVWGRFMARALEKEPPKEFPWLSEVKISKRTVCRMSGKLPSGQCHDLLE CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH EYFIPQTVPKDVCNDHGSAWNVVETKTQNPVTQKPAEPKKQDTKVEKKPSESKPPKRKKS HHCCCCCCCHHHHCCCCCCCCEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHH VFSGDEEIDY HCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA