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The map label for this gene is expZ [H]

Identifier: 183220747

GI number: 183220747

Start: 1413107

End: 1414615

Strand: Direct

Name: expZ [H]

Synonym: LEPBI_I1357

Alternate gene names: 183220747

Gene position: 1413107-1414615 (Clockwise)

Preceding gene: 183220746

Following gene: 183220748

Centisome position: 39.26

GC content: 41.62

Gene sequence:

>1509_bases
ATGTCCAAAACCCTTCGCATTCATAACGGAACCTTTCGTTACGAAACCCACTCTTCACCCATCTTTGAAAACTTGAATGT
CCACTTTTCATCGGGTTGGACCGGACTTATTGGCAAAAATGGAAGTGGTAAGTCAACTCTTGCCAAAATCATTTCACGTG
AACTTACGTTAGACGAAGGATCGATCATCGGTTCGCACCATGTATTGTATCTTTCTCAAGGAACTGAAATGGAGTTAGAA
GAGTTGAGAGAGTTTTTCTACGATGATTCCAAAGAGACTGGATTTTGGAAAAGCCTATTGCAAATCAAAATCCAACAAGC
CGAGGATTATGAAACTCTAAGTTTTGGTGAAAAACGAAAACTTCTCCTTTCTCAAATTCTATCAAAAAAACCAGAGGTTC
TCATCCTTGATGAACCAACGAACCATTTGGATTTGAAAAGCCAAATGATCCTGCGTGAAGCCATGCGGGCATATAATGGG
ATTGGGATTTTGATTAGCCACGACAGGTCATTGTTAGATGAGGTGACTTCGTCGTGTATCTTTCTTGAAAAAAACTTTTT
GGAGCAAAGGCCCGGAAATTATTCGGAAGGCAAACGCGAAAGAGACAAAGAGGCAAAGGCCAGGATCCACCAATGGCAAA
CCGCCAAAGTAGAACGGAAAAAATTGGAGAAGGAATGGAAACGGAGAAGGGAAGAAGCAAACCTTTCCCACAACAAAAGG
TCCAAAAAAGGATTGGATCTCCATGACCATGATGGGAGGGCTAAAAAAGATTTAGTTCGAGTTTCTGGTAAAGATGGACA
GGCAGGCCGATTAAAAAACCAAATCGAACGTAGGACAGAGATAAGCGCCGAAAGGGAAAAACAAATTTGGGAAACTTTGC
CAGAAAAAGAAACGATTGGCATCGAGTGGCAGAATCTTCAAACAAAACGGAACCATTTGTTTTTGTATGAAGGTGAAAGG
TTAGTCCTTCCTTTTCTCTCTTTGGAATTAGAGTTCCATTTATCGATTCGATCCCAATCGAGGATTGCAGTCACAGGTGC
GAATGGTTCGGGTAAATCGAGTTTGTTAAGGCATCTTATCGAAGATTTTAAGGAAAGAAAAATTGCAACCGTTTACCTCC
CTCAAGAATTTTCAAAACAGGAACTTACGGTTTTACTCCAAACCTTTCAATCCTCAAATGATTCGAAACAGGCAGACATA
CTTTCCATTGTCCATCGATTGGGAGGTGATCCCAAACGATTTTTGGAATCGGAGGCTTTGAGCCCAGGTGAAGGAAAAAA
ACTTTTCCTGGCACTCCATCTCGATACGTATCCAGAGGTGCTTGTCTTAGACGAACCAACCAACCATTTGGATTTAAAAT
CGATTGAAGCATTGGAAACATCCTTACAAGAATGGAAGGGGACACTCATCCTTGTGAGCCATGACCAGAGGTTTCTCCAA
ACCTTGGCAAGTGAGGAGTGGGATTTGGAAAACTTCCGGCTCAGACAAAAACATCTAGACAGAATCTAA

Upstream 100 bases:

>100_bases
TAAGCAAAAAAAAACAAACCAACATTTCCACTTCTCCTGAATCAAATTAGGACAAGACTTGCTTACCGTTTTCAATTGGA
AACTTTTAGGAGCATGTTTT

Downstream 100 bases:

>100_bases
GCATTGTACTTAGAATAATTCTAAGGAGTGACATTATGCCACAAGTGACATCACATGCCCCTGATTTTAAAGCAACCGCA
GTGATCGGGGACAGTTTCAA

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSKTLRIHNGTFRYETHSSPIFENLNVHFSSGWTGLIGKNGSGKSTLAKIISRELTLDEGSIIGSHHVLYLSQGTEMELE
ELREFFYDDSKETGFWKSLLQIKIQQAEDYETLSFGEKRKLLLSQILSKKPEVLILDEPTNHLDLKSQMILREAMRAYNG
IGILISHDRSLLDEVTSSCIFLEKNFLEQRPGNYSEGKRERDKEAKARIHQWQTAKVERKKLEKEWKRRREEANLSHNKR
SKKGLDLHDHDGRAKKDLVRVSGKDGQAGRLKNQIERRTEISAEREKQIWETLPEKETIGIEWQNLQTKRNHLFLYEGER
LVLPFLSLELEFHLSIRSQSRIAVTGANGSGKSSLLRHLIEDFKERKIATVYLPQEFSKQELTVLLQTFQSSNDSKQADI
LSIVHRLGGDPKRFLESEALSPGEGKKLFLALHLDTYPEVLVLDEPTNHLDLKSIEALETSLQEWKGTLILVSHDQRFLQ
TLASEEWDLENFRLRQKHLDRI

Sequences:

>Translated_502_residues
MSKTLRIHNGTFRYETHSSPIFENLNVHFSSGWTGLIGKNGSGKSTLAKIISRELTLDEGSIIGSHHVLYLSQGTEMELE
ELREFFYDDSKETGFWKSLLQIKIQQAEDYETLSFGEKRKLLLSQILSKKPEVLILDEPTNHLDLKSQMILREAMRAYNG
IGILISHDRSLLDEVTSSCIFLEKNFLEQRPGNYSEGKRERDKEAKARIHQWQTAKVERKKLEKEWKRRREEANLSHNKR
SKKGLDLHDHDGRAKKDLVRVSGKDGQAGRLKNQIERRTEISAEREKQIWETLPEKETIGIEWQNLQTKRNHLFLYEGER
LVLPFLSLELEFHLSIRSQSRIAVTGANGSGKSSLLRHLIEDFKERKIATVYLPQEFSKQELTVLLQTFQSSNDSKQADI
LSIVHRLGGDPKRFLESEALSPGEGKKLFLALHLDTYPEVLVLDEPTNHLDLKSIEALETSLQEWKGTLILVSHDQRFLQ
TLASEEWDLENFRLRQKHLDRI
>Mature_501_residues
SKTLRIHNGTFRYETHSSPIFENLNVHFSSGWTGLIGKNGSGKSTLAKIISRELTLDEGSIIGSHHVLYLSQGTEMELEE
LREFFYDDSKETGFWKSLLQIKIQQAEDYETLSFGEKRKLLLSQILSKKPEVLILDEPTNHLDLKSQMILREAMRAYNGI
GILISHDRSLLDEVTSSCIFLEKNFLEQRPGNYSEGKRERDKEAKARIHQWQTAKVERKKLEKEWKRRREEANLSHNKRS
KKGLDLHDHDGRAKKDLVRVSGKDGQAGRLKNQIERRTEISAEREKQIWETLPEKETIGIEWQNLQTKRNHLFLYEGERL
VLPFLSLELEFHLSIRSQSRIAVTGANGSGKSSLLRHLIEDFKERKIATVYLPQEFSKQELTVLLQTFQSSNDSKQADIL
SIVHRLGGDPKRFLESEALSPGEGKKLFLALHLDTYPEVLVLDEPTNHLDLKSIEALETSLQEWKGTLILVSHDQRFLQT
LASEEWDLENFRLRQKHLDRI

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=407, Percent_Identity=25.5528255528256, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI10947135, Length=548, Percent_Identity=24.8175182481752, Blast_Score=109, Evalue=8e-24,
Organism=Homo sapiens, GI69354671, Length=548, Percent_Identity=24.8175182481752, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI27881506, Length=204, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI10947137, Length=204, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1787041, Length=534, Percent_Identity=28.8389513108614, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787182, Length=535, Percent_Identity=26.5420560747664, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1789751, Length=517, Percent_Identity=26.1121856866538, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI2367384, Length=553, Percent_Identity=26.4014466546112, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17555318, Length=523, Percent_Identity=25.4302103250478, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17553372, Length=392, Percent_Identity=26.0204081632653, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17559834, Length=567, Percent_Identity=23.2804232804233, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321121, Length=405, Percent_Identity=26.4197530864197, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320874, Length=515, Percent_Identity=24.2718446601942, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325030, Length=79, Percent_Identity=39.2405063291139, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324314, Length=178, Percent_Identity=31.4606741573034, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323278, Length=171, Percent_Identity=29.8245614035088, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24666836, Length=404, Percent_Identity=28.4653465346535, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24642252, Length=412, Percent_Identity=26.9417475728155, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18859989, Length=412, Percent_Identity=26.9417475728155, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641342, Length=551, Percent_Identity=24.1379310344828, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 58125; Mature: 57994

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTLRIHNGTFRYETHSSPIFENLNVHFSSGWTGLIGKNGSGKSTLAKIISRELTLDEG
CCCEEEEECCEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCC
SIIGSHHVLYLSQGTEMELEELREFFYDDSKETGFWKSLLQIKIQQAEDYETLSFGEKRK
CEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCHHHH
LLLSQILSKKPEVLILDEPTNHLDLKSQMILREAMRAYNGIGILISHDRSLLDEVTSSCI
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHEE
FLEKNFLEQRPGNYSEGKRERDKEAKARIHQWQTAKVERKKLEKEWKRRREEANLSHNKR
EHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SKKGLDLHDHDGRAKKDLVRVSGKDGQAGRLKNQIERRTEISAEREKQIWETLPEKETIG
CCCCCCCCCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
IEWQNLQTKRNHLFLYEGERLVLPFLSLELEFHLSIRSQSRIAVTGANGSGKSSLLRHLI
EEECCCCCCCCEEEEEECCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHH
EDFKERKIATVYLPQEFSKQELTVLLQTFQSSNDSKQADILSIVHRLGGDPKRFLESEAL
HHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCC
SPGEGKKLFLALHLDTYPEVLVLDEPTNHLDLKSIEALETSLQEWKGTLILVSHDQRFLQ
CCCCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHH
TLASEEWDLENFRLRQKHLDRI
HHHCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SKTLRIHNGTFRYETHSSPIFENLNVHFSSGWTGLIGKNGSGKSTLAKIISRELTLDEG
CCEEEEECCEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCC
SIIGSHHVLYLSQGTEMELEELREFFYDDSKETGFWKSLLQIKIQQAEDYETLSFGEKRK
CEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCHHHH
LLLSQILSKKPEVLILDEPTNHLDLKSQMILREAMRAYNGIGILISHDRSLLDEVTSSCI
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHEE
FLEKNFLEQRPGNYSEGKRERDKEAKARIHQWQTAKVERKKLEKEWKRRREEANLSHNKR
EHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SKKGLDLHDHDGRAKKDLVRVSGKDGQAGRLKNQIERRTEISAEREKQIWETLPEKETIG
CCCCCCCCCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
IEWQNLQTKRNHLFLYEGERLVLPFLSLELEFHLSIRSQSRIAVTGANGSGKSSLLRHLI
EEECCCCCCCCEEEEEECCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHH
EDFKERKIATVYLPQEFSKQELTVLLQTFQSSNDSKQADILSIVHRLGGDPKRFLESEAL
HHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCC
SPGEGKKLFLALHLDTYPEVLVLDEPTNHLDLKSIEALETSLQEWKGTLILVSHDQRFLQ
CCCCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHH
TLASEEWDLENFRLRQKHLDRI
HHHCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]