Click here to switch to the map view.

The map label for this gene is lldD [H]

Identifier: 183220731

GI number: 183220731

Start: 1394971

End: 1397223

Strand: Direct

Name: lldD [H]

Synonym: LEPBI_I1341

Alternate gene names: 183220731

Gene position: 1394971-1397223 (Clockwise)

Preceding gene: 183220730

Following gene: 183220732

Centisome position: 38.75

GC content: 44.74

Gene sequence:

>2253_bases
TTGAAATCAGTTGAAGGAAAAACAATCCTCATCATCGGCGGAGGGTTGTTACAAGTTCCCATCATCCAAACAGCAAAAAC
CATGCGACTGCATACCGTGGTTGCTGATATGAATCCCACTTCCATTGGCTTCCAAATTGCCGATGAAACCATCCTCATGT
CCACAAAAGACGTGGAAGGTATGGTGCGTGAGGCAAAAAAGTTTTCACAGAAGACAACGATCCATGGAGTGATCACCGCA
GGGACTGACGCCAGTATGACAGTGGCGGCTGTTGCTTCGGCATTACAGCTCCCAGGGATTCGGTTTGTGGATGCAGAAGC
GGCTTCCAATAAAGTGAAGATGCGAAAACGCCTAAAAGAATTTGGCCTTCCCATCCCTCGTTTTGCACCTGTTTGGTCCA
TGCAAGATGCAAAAGATGCGTTAGATGAGTTAACTTTCCCACTTGTGATGAAACCGGCCGACAATATGGGGGCTCGCGGT
GTGATCAAGGTCACAAACCGTGACGACTTACAAGTTGCTTTTCGCCATGCCAAACGATTCTGTCCTACGGGTGAATTGAT
ATTAGAAGAATATATGGAAGGACCAGAACTATCCGTGGATGCCCTTGCTTTCCAAGGCCAAATCCGCATGACAGGGATTG
CTGACAGGATCATCGAAAGGGAACCATACTTCATTGAAGTTGGGCATAATATGCCCTCTAGTTTACCGAAAGATGTTTTG
GATGAAGTGGAACGTGTGATGGCAGGAGGCATGAGAGCCCTTGGCATTCATTTGGGTGCGGGAAAAGGAGATATCAAAGT
CACAAAAGACGGAGTGAAAATTGGTGAAATTGCCGCTAGACTTTCAGGTGGTTTTATGTCGGCTTTCACCTATCCCTTAT
CAACCGGTGTGAATCTCAATCGTGCCGCACTCCTCATTTCCCTTGGGGAAACTCCAGACAATTTAGAACCCGTATTCCAT
CGAGTTTCCATTGAACGATCGTTATTATCCAAACCAGGAAAACTCATCTGCATTAGTGGTGTCGAAGAAATCAAAAAAAT
TGATGGTGTTGCGGAAGTATTCCTTCAATCCAAACCAGGGGACATTATCAAGGAACCGACAAATAACATTGATAAGTCGG
GTCACGTCATCATCGTCTCAGACAGTTTAAAAGAAGCCGAACAAGTGTTTGCAAAAGTCAAACAAACCATTCGATTTGAA
GTGGATGAACAATTTTCCATTACTGAAAAAGAAATTGCTGACCAAGCAAGGATTCGTTTTGGAAAAGATATCTGTTGGGT
TTGTAAGGTCTGTGATGGGAAAAATTGTGCCTCAGGGATTCCTGGTATGGGTGGAGTGGGCCTTATGGAAACTTTCCAAG
ACAACCATGAAGCTCTCGCAGAGTATAAAATTTTGCCAGGTTACATCCGTGATCACGTGTCACCCAATATCCAATCTCAA
TTTTTAGGTTATGATTTAAAAACGCCGATCATGGCGGCCCCCATGACAGGTGTTGGCACCAATATGAACTTTGTCATGAC
AGATGCTGATTATGCCCTTACAGTAGTTCGTTCTTTTTCTCAAAATGGAAGTCTAGCTTGGCTTGGTGATGGTGCCTCAC
CTGAAAAATACAAAATCATGCTCGATGCCTTAAAAAAAGTAAATGGAAAAGGGATTCTCATTTGTAAACCAAGGTTAGAT
GAGTCACTGCTTCTAGATCGATTTTTACAAGCGGAAGCGGACGGAGTGTTCGCCATCGGAATGGACATCGATGCTGTTAA
TTTTAGAACCATGGTGCAAAAGAATCTTTCCAGCGTGACACGTCCACTGGATGCTCTCATCAAACTAAAAGGAAAAACAA
AACTCCCTTTCATCTTAAAAGGCATTATGAACCCAGAAGATGCAAAACTGGCAGTGGATGGTGGATTTTCCGCCATCGTG
GTGTCAAACCATGGAGGTCGGGTCCTTGATGGGATGCCAGGGACGGCAAGGGTGCTACCAAAGATTGCCGAAGTGGTAAA
AGGGAAAATCCCAATCCTTGTGGATGGGGGAGTTCGATCCGGTATGGATGTATTTAAGATGATTGCCCTCGGAGCAGATG
CAGTGCTTGTGGGAAGGCCCGTTGCGATTTCGCTCGTGGGAGGTGAAGATGCCGGGATTCGATTTCTTTTACAAAAATAT
TCGGAAGAACTAAAACAGTCTATGAGTGTGACAGGTGCGAAAACTTTGGTAGACATCAAGCGTTCCATGTTACTTCATAA
ACAACACGGTTGA

Upstream 100 bases:

>100_bases
CAAACGGAGATTATCTCTTCGCGGGTGGAATCATCCAAAAAGGTTCCATCACTCGTAAAATCAAATCAAACGTGGAAGTT
CAAAGGGAGAGTGTTCCCAT

Downstream 100 bases:

>100_bases
GTATGGACAAAGAAATCAAAGACCCTGAAGGTATTTTGAAGGTAATTACCGCCTTATTTGGAAAATTACCGGCATACATC
GTCAACTCAGAGAAAGAATT

Product: putative oxidase or carboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 750; Mature: 750

Protein sequence:

>750_residues
MKSVEGKTILIIGGGLLQVPIIQTAKTMRLHTVVADMNPTSIGFQIADETILMSTKDVEGMVREAKKFSQKTTIHGVITA
GTDASMTVAAVASALQLPGIRFVDAEAASNKVKMRKRLKEFGLPIPRFAPVWSMQDAKDALDELTFPLVMKPADNMGARG
VIKVTNRDDLQVAFRHAKRFCPTGELILEEYMEGPELSVDALAFQGQIRMTGIADRIIEREPYFIEVGHNMPSSLPKDVL
DEVERVMAGGMRALGIHLGAGKGDIKVTKDGVKIGEIAARLSGGFMSAFTYPLSTGVNLNRAALLISLGETPDNLEPVFH
RVSIERSLLSKPGKLICISGVEEIKKIDGVAEVFLQSKPGDIIKEPTNNIDKSGHVIIVSDSLKEAEQVFAKVKQTIRFE
VDEQFSITEKEIADQARIRFGKDICWVCKVCDGKNCASGIPGMGGVGLMETFQDNHEALAEYKILPGYIRDHVSPNIQSQ
FLGYDLKTPIMAAPMTGVGTNMNFVMTDADYALTVVRSFSQNGSLAWLGDGASPEKYKIMLDALKKVNGKGILICKPRLD
ESLLLDRFLQAEADGVFAIGMDIDAVNFRTMVQKNLSSVTRPLDALIKLKGKTKLPFILKGIMNPEDAKLAVDGGFSAIV
VSNHGGRVLDGMPGTARVLPKIAEVVKGKIPILVDGGVRSGMDVFKMIALGADAVLVGRPVAISLVGGEDAGIRFLLQKY
SEELKQSMSVTGAKTLVDIKRSMLLHKQHG

Sequences:

>Translated_750_residues
MKSVEGKTILIIGGGLLQVPIIQTAKTMRLHTVVADMNPTSIGFQIADETILMSTKDVEGMVREAKKFSQKTTIHGVITA
GTDASMTVAAVASALQLPGIRFVDAEAASNKVKMRKRLKEFGLPIPRFAPVWSMQDAKDALDELTFPLVMKPADNMGARG
VIKVTNRDDLQVAFRHAKRFCPTGELILEEYMEGPELSVDALAFQGQIRMTGIADRIIEREPYFIEVGHNMPSSLPKDVL
DEVERVMAGGMRALGIHLGAGKGDIKVTKDGVKIGEIAARLSGGFMSAFTYPLSTGVNLNRAALLISLGETPDNLEPVFH
RVSIERSLLSKPGKLICISGVEEIKKIDGVAEVFLQSKPGDIIKEPTNNIDKSGHVIIVSDSLKEAEQVFAKVKQTIRFE
VDEQFSITEKEIADQARIRFGKDICWVCKVCDGKNCASGIPGMGGVGLMETFQDNHEALAEYKILPGYIRDHVSPNIQSQ
FLGYDLKTPIMAAPMTGVGTNMNFVMTDADYALTVVRSFSQNGSLAWLGDGASPEKYKIMLDALKKVNGKGILICKPRLD
ESLLLDRFLQAEADGVFAIGMDIDAVNFRTMVQKNLSSVTRPLDALIKLKGKTKLPFILKGIMNPEDAKLAVDGGFSAIV
VSNHGGRVLDGMPGTARVLPKIAEVVKGKIPILVDGGVRSGMDVFKMIALGADAVLVGRPVAISLVGGEDAGIRFLLQKY
SEELKQSMSVTGAKTLVDIKRSMLLHKQHG
>Mature_750_residues
MKSVEGKTILIIGGGLLQVPIIQTAKTMRLHTVVADMNPTSIGFQIADETILMSTKDVEGMVREAKKFSQKTTIHGVITA
GTDASMTVAAVASALQLPGIRFVDAEAASNKVKMRKRLKEFGLPIPRFAPVWSMQDAKDALDELTFPLVMKPADNMGARG
VIKVTNRDDLQVAFRHAKRFCPTGELILEEYMEGPELSVDALAFQGQIRMTGIADRIIEREPYFIEVGHNMPSSLPKDVL
DEVERVMAGGMRALGIHLGAGKGDIKVTKDGVKIGEIAARLSGGFMSAFTYPLSTGVNLNRAALLISLGETPDNLEPVFH
RVSIERSLLSKPGKLICISGVEEIKKIDGVAEVFLQSKPGDIIKEPTNNIDKSGHVIIVSDSLKEAEQVFAKVKQTIRFE
VDEQFSITEKEIADQARIRFGKDICWVCKVCDGKNCASGIPGMGGVGLMETFQDNHEALAEYKILPGYIRDHVSPNIQSQ
FLGYDLKTPIMAAPMTGVGTNMNFVMTDADYALTVVRSFSQNGSLAWLGDGASPEKYKIMLDALKKVNGKGILICKPRLD
ESLLLDRFLQAEADGVFAIGMDIDAVNFRTMVQKNLSSVTRPLDALIKLKGKTKLPFILKGIMNPEDAKLAVDGGFSAIV
VSNHGGRVLDGMPGTARVLPKIAEVVKGKIPILVDGGVRSGMDVFKMIALGADAVLVGRPVAISLVGGEDAGIRFLLQKY
SEELKQSMSVTGAKTLVDIKRSMLLHKQHG

Specific function: Unknown

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=335, Percent_Identity=29.5522388059701, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI54234014, Length=331, Percent_Identity=28.0966767371601, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI7705393, Length=331, Percent_Identity=28.0966767371601, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1790033, Length=131, Percent_Identity=50.381679389313, Blast_Score=129, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI193208036, Length=138, Percent_Identity=38.4057971014493, Blast_Score=110, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323587, Length=142, Percent_Identity=35.9154929577465, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281363140, Length=191, Percent_Identity=32.4607329842932, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI78707190, Length=191, Percent_Identity=32.4607329842932, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI78707188, Length=191, Percent_Identity=32.4607329842932, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 81257; Mature: 81257

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVEGKTILIIGGGLLQVPIIQTAKTMRLHTVVADMNPTSIGFQIADETILMSTKDVEG
CCCCCCCEEEEECCCEEEECHHHHHHHEEEEEEEECCCCCCCCEEEECCEEEEECHHHHH
MVREAKKFSQKTTIHGVITAGTDASMTVAAVASALQLPGIRFVDAEAASNKVKMRKRLKE
HHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHH
FGLPIPRFAPVWSMQDAKDALDELTFPLVMKPADNMGARGVIKVTNRDDLQVAFRHAKRF
HCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHC
CPTGELILEEYMEGPELSVDALAFQGQIRMTGIADRIIEREPYFIEVGHNMPSSLPKDVL
CCCHHHHHHHHHCCCCCEEEEEEECCCEEEEHHHHHHHCCCCCEEEECCCCCCCCHHHHH
DEVERVMAGGMRALGIHLGAGKGDIKVTKDGVKIGEIAARLSGGFMSAFTYPLSTGVNLN
HHHHHHHHCCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCC
RAALLISLGETPDNLEPVFHRVSIERSLLSKPGKLICISGVEEIKKIDGVAEVFLQSKPG
CEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCC
DIIKEPTNNIDKSGHVIIVSDSLKEAEQVFAKVKQTIRFEVDEQFSITEKEIADQARIRF
CHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHC
GKDICWVCKVCDGKNCASGIPGMGGVGLMETFQDNHEALAEYKILPGYIRDHVSPNIQSQ
CCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCCHHH
FLGYDLKTPIMAAPMTGVGTNMNFVMTDADYALTVVRSFSQNGSLAWLGDGASPEKYKIM
HCCCCCCCCCEECCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
LDALKKVNGKGILICKPRLDESLLLDRFLQAEADGVFAIGMDIDAVNFRTMVQKNLSSVT
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECEECCHHHHHHHHHHHHHHH
RPLDALIKLKGKTKLPFILKGIMNPEDAKLAVDGGFSAIVVSNHGGRVLDGMPGTARVLP
HHHHHHHEECCCCCCCHHHHHCCCCCCCEEEEECCEEEEEEECCCCEEECCCCCHHHHHH
KIAEVVKGKIPILVDGGVRSGMDVFKMIALGADAVLVGRPVAISLVGGEDAGIRFLLQKY
HHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCEEEEEECCCCHHHHHHHHHH
SEELKQSMSVTGAKTLVDIKRSMLLHKQHG
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSVEGKTILIIGGGLLQVPIIQTAKTMRLHTVVADMNPTSIGFQIADETILMSTKDVEG
CCCCCCCEEEEECCCEEEECHHHHHHHEEEEEEEECCCCCCCCEEEECCEEEEECHHHHH
MVREAKKFSQKTTIHGVITAGTDASMTVAAVASALQLPGIRFVDAEAASNKVKMRKRLKE
HHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHH
FGLPIPRFAPVWSMQDAKDALDELTFPLVMKPADNMGARGVIKVTNRDDLQVAFRHAKRF
HCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHC
CPTGELILEEYMEGPELSVDALAFQGQIRMTGIADRIIEREPYFIEVGHNMPSSLPKDVL
CCCHHHHHHHHHCCCCCEEEEEEECCCEEEEHHHHHHHCCCCCEEEECCCCCCCCHHHHH
DEVERVMAGGMRALGIHLGAGKGDIKVTKDGVKIGEIAARLSGGFMSAFTYPLSTGVNLN
HHHHHHHHCCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCC
RAALLISLGETPDNLEPVFHRVSIERSLLSKPGKLICISGVEEIKKIDGVAEVFLQSKPG
CEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCC
DIIKEPTNNIDKSGHVIIVSDSLKEAEQVFAKVKQTIRFEVDEQFSITEKEIADQARIRF
CHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHC
GKDICWVCKVCDGKNCASGIPGMGGVGLMETFQDNHEALAEYKILPGYIRDHVSPNIQSQ
CCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCCHHH
FLGYDLKTPIMAAPMTGVGTNMNFVMTDADYALTVVRSFSQNGSLAWLGDGASPEKYKIM
HCCCCCCCCCEECCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
LDALKKVNGKGILICKPRLDESLLLDRFLQAEADGVFAIGMDIDAVNFRTMVQKNLSSVT
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECEECCHHHHHHHHHHHHHHH
RPLDALIKLKGKTKLPFILKGIMNPEDAKLAVDGGFSAIVVSNHGGRVLDGMPGTARVLP
HHHHHHHEECCCCCCCHHHHHCCCCCCCEEEEECCEEEEEEECCCCEEECCCCCHHHHHH
KIAEVVKGKIPILVDGGVRSGMDVFKMIALGADAVLVGRPVAISLVGGEDAGIRFLLQKY
HHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCEEEEEECCCCHHHHHHHHHH
SEELKQSMSVTGAKTLVDIKRSMLLHKQHG
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA