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The map label for this gene is mtnD [H]

Identifier: 183220698

GI number: 183220698

Start: 1362970

End: 1363509

Strand: Direct

Name: mtnD [H]

Synonym: LEPBI_I1308

Alternate gene names: 183220698

Gene position: 1362970-1363509 (Clockwise)

Preceding gene: 183220697

Following gene: 183220701

Centisome position: 37.86

GC content: 41.67

Gene sequence:

>540_bases
ATGGAAATGGCAACGATAGTCAAAAAACAAGAAACGATCCAGGACAAAGACCAAGTGAAAGCATACCTGACCCAAAAAGG
GCTTGTGTATGAATCTTACAAAACTCCTGAATCTTTGGATTTGATCCTCGGCCAAAAAGGTTTATCCGATGCGGAAAAAG
AAGAAGTCCTTTCTGGTCTGGAATACCGATTTGACCAATTGAAAAAACAACATGGCTACAAAGCAAACGACCTTGTGGTC
CTTCATGACGAAGTGCCAGGGATCAGTGACATGTTAGCTAAATTTGACAAACTTCACATCCATACAGATGAAGAAGTTCG
TTACATCATTGATGGGAGTGGGATTTTTGGCTTCATCATTGACGGAGAACGATTTGAAGTCCATGTTGGGAAAGGTGATT
TTATCTCCATCCCTGCCAATACAAACCACTGGTTCACATTGGACCAAACAATGCGGATCAAAGCCGTTCGATACTTTAAG
GACAACTCAGGTTGGACACCCGTTTATGTGGATGAATCGAAAGTCCTCATCAATGCATAA

Upstream 100 bases:

>100_bases
GGATCCCTTTTGTAATTCTGTTATAGCAGAATTACATCCAGGATAGCGAAAAACAAGTTGCTTCCCAATCCCAGGGGAAA
AGGCTTGCCTAAGTAGGTAA

Downstream 100 bases:

>100_bases
TTGTATTTGAACACTTCTTTTCTTGTATAAGAACCAAATCCTTCATTCGCCTGTTAGGCGGGTGATGGATTTTAGGATTC
TGCTTTTCCAAACCATTCCA

Product: putative acireductone dioxygenase, ARD

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MEMATIVKKQETIQDKDQVKAYLTQKGLVYESYKTPESLDLILGQKGLSDAEKEEVLSGLEYRFDQLKKQHGYKANDLVV
LHDEVPGISDMLAKFDKLHIHTDEEVRYIIDGSGIFGFIIDGERFEVHVGKGDFISIPANTNHWFTLDQTMRIKAVRYFK
DNSGWTPVYVDESKVLINA

Sequences:

>Translated_179_residues
MEMATIVKKQETIQDKDQVKAYLTQKGLVYESYKTPESLDLILGQKGLSDAEKEEVLSGLEYRFDQLKKQHGYKANDLVV
LHDEVPGISDMLAKFDKLHIHTDEEVRYIIDGSGIFGFIIDGERFEVHVGKGDFISIPANTNHWFTLDQTMRIKAVRYFK
DNSGWTPVYVDESKVLINA
>Mature_179_residues
MEMATIVKKQETIQDKDQVKAYLTQKGLVYESYKTPESLDLILGQKGLSDAEKEEVLSGLEYRFDQLKKQHGYKANDLVV
LHDEVPGISDMLAKFDKLHIHTDEEVRYIIDGSGIFGFIIDGERFEVHVGKGDFISIPANTNHWFTLDQTMRIKAVRYFK
DNSGWTPVYVDESKVLINA

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family [H]

Homologues:

Organism=Homo sapiens, GI171460928, Length=120, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161082987, Length=105, Percent_Identity=38.0952380952381, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710 [H]

Pfam domain/function: PF03079 ARD [H]

EC number: =1.13.11.54; =1.13.11.53 [H]

Molecular weight: Translated: 20488; Mature: 20488

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMATIVKKQETIQDKDQVKAYLTQKGLVYESYKTPESLDLILGQKGLSDAEKEEVLSGL
CCHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHH
EYRFDQLKKQHGYKANDLVVLHDEVPGISDMLAKFDKLHIHTDEEVRYIIDGSGIFGFII
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHEEEECCCCEEEEEECCCEEEEEE
DGERFEVHVGKGDFISIPANTNHWFTLDQTMRIKAVRYFKDNSGWTPVYVDESKVLINA
ECCEEEEEECCCCEEEECCCCCCEEEECCCEEEEEEEEEECCCCCCEEEECCCEEEEEC
>Mature Secondary Structure
MEMATIVKKQETIQDKDQVKAYLTQKGLVYESYKTPESLDLILGQKGLSDAEKEEVLSGL
CCHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHH
EYRFDQLKKQHGYKANDLVVLHDEVPGISDMLAKFDKLHIHTDEEVRYIIDGSGIFGFII
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHEEEECCCCEEEEEECCCEEEEEE
DGERFEVHVGKGDFISIPANTNHWFTLDQTMRIKAVRYFKDNSGWTPVYVDESKVLINA
ECCEEEEEECCCCEEEECCCCCCEEEECCCEEEEEEEEEECCCCCCEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA