| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is ispG [H]
Identifier: 183220675
GI number: 183220675
Start: 1340001
End: 1342028
Strand: Reverse
Name: ispG [H]
Synonym: LEPBI_I1285
Alternate gene names: 183220675
Gene position: 1342028-1340001 (Counterclockwise)
Preceding gene: 183220699
Following gene: 183220674
Centisome position: 37.28
GC content: 42.46
Gene sequence:
>2028_bases ATGAGCACCAAATATAACGAATCACCATTTTTCTACAGAAGGCGTCCCACTCGGGAAGTGAAAGTGGGAGACGTTGGAAT CGGAGGGAAAAACCCCATCCGTGTCCAATCCATGATCACATCTAACACAAGAGATACGGATGCAAGTATCCAACAAATTA TGGATTTGGAAAGAGCTGGTTCAGAGATTGTTCGCCTAACAGTTCCCAGCCAAGCCGACGCAGATAATTTGCCCAATATT CGAAAAAAGATGAAAGAACTCGGATTAAAAGTCCCTCTTGTGGCAGACATTCACTTCACACCACAAGTTGCCTTAAAATG TGTGGAATGGGTAGAAAAGGTGCGAATCAACCCAGGAAACTTTGCTGACAAAAAAAAATTTGAAATCATCGAATACACAG ACAATGACTATCACGAAGAACTGGCAAGGATAGAAGAAGTATTCACTCCCCTAGTCCTCCGAGCCAAAGAATTGGGAGTG GCGATGCGGATTGGAACCAACCATGGAAGTTTATCCGACCGGATCATGAACCGATTTGGAGACACTCCCCTTGGGATGGT GGAGTCTGCTTTAGAATTCATTCGGATTGCCGAAAAAAATTCTTATCGTGACATTGTTGTTTCCATGAAGGCATCCAATC CCCAAGTGATGATCCAAGCCTATCGTATGTTAGTGGCTCGTTTTTATGATTTAGGAATGGATTATCCCTTACATTTAGGT GTGACGGAAGCAGGGGATGGAAAAGACGGAAGGATTAAGTCTGCCATTGGGATTGGAAGTTTACTTGAAGATGGACTTGG TGATACGGTTCGAGTGTCTCTCACAGAAGATGCCATCCATGAAATCCCCGTTGCCAAGGAACTGGTCCGCAAATACAATG ATCTCTTTTTTGCATCGCTTACGACAAAAGAAAATTCTATCCCAAAAGAAAGGGAAATCATTTATACTGAGTTCAGAGAC CCTTACCAATACTCACGCTTTTATTCCAAAGAACTTATGATTGGCGAAAGTAAAATCGGAGACTCAAATCCGGTGCGAAT CGAATCTTGTTTTCCTTTTTTTGGCGAGGGAACCGAAGAAGAAGTCCTCCATCTCATCCAAAGGGGCGCCAAATCAGGCC GTGTTCCTGAACTCATGCATTTCCAGATCAATTCCGAATTGGATTTACTCTCTCTTGGGACGATGACAAGAAGAGGTTCT TTTCCTTTGCCGGTTTCTGTTTCACTTTCCGAGGAGCTTCTCTACCAATATGATGCCCTTGCAGAAGACTTGTACCGATT CCAAAAATGGGTAATTTCACCATCTCTATTTTTGAAAGAGTCTGAAGAATCTTGGGATGACCTTTTACAGTTTGTGTCCC GATTTGCTAAAGACAAACGTTCGGTGGAATGGACTTTTTCATCCACTCACATAGAACAGGCGACTGTAGTTTTAAAAGAA TGTAAAAAACGAAAAATCGAAAATATTTTATTTTCTGTGAGTGATGGAGACCTTCTCTCATTACGAAAACTTGCCTGCCT TTTGCAAGAATCAGATTACCCTATTGTATTGAATGTTTCTGCAAAAAACAAAGACCAATTGATGTATGATGCCTCCATTA AAGCCGGAGGAAGTTTACTCGATGGGATTGGAGATGTCATCAGACTTTCTTTTGGTGATGGAGAGGCCGAAGAGTGTTTG CATTTGAGTTTTGATATTTTACAAGCCACGCGCCTTCGATTGACCAAAACAGAATACATTTCTTGTCCTTCTTGTGGGCG GACGATGTTTGACTTACAATCCACAACGGCAAAAATCAAAGAAAAAACCGGCCACTTAAAAGGCGTAAAAATTGCTGTCA TGGGTTGCATTGTGAATGGACCAGGTGAGATGGCAGATGCTGATTTTGGTTATGTGGGGGCCGGGGTCGGTAAGGTTCAC CTCTACAAAGGAAAGGAAATTGTCAAAAAAGGAGTCTCGGAAACAGAAGCTCCCGATTTACTCATCGAACTCATCCGTGA AAATGGAATGTGGAACGATCCAGCATAA
Upstream 100 bases:
>100_bases GGTTTGGGAGGGAGTGAAATTGAAAGTCTCAGATTTTTTTCATACTGCTTGCCCAAAATTTCGAATTTAATTTTCTAGAT AATGAGAACATAAGATTCAA
Downstream 100 bases:
>100_bases AAAATAGTATCCATTCGATTCTTCTATCTGTAATCTCATCCAGGTGGAAGAAAAAGAAAAAAAAGAAATTTTATCTAAAA TCCAATCCATGGAGAAAGAA
Product: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
Products: NA
Alternate protein names: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [H]
Number of amino acids: Translated: 675; Mature: 674
Protein sequence:
>675_residues MSTKYNESPFFYRRRPTREVKVGDVGIGGKNPIRVQSMITSNTRDTDASIQQIMDLERAGSEIVRLTVPSQADADNLPNI RKKMKELGLKVPLVADIHFTPQVALKCVEWVEKVRINPGNFADKKKFEIIEYTDNDYHEELARIEEVFTPLVLRAKELGV AMRIGTNHGSLSDRIMNRFGDTPLGMVESALEFIRIAEKNSYRDIVVSMKASNPQVMIQAYRMLVARFYDLGMDYPLHLG VTEAGDGKDGRIKSAIGIGSLLEDGLGDTVRVSLTEDAIHEIPVAKELVRKYNDLFFASLTTKENSIPKEREIIYTEFRD PYQYSRFYSKELMIGESKIGDSNPVRIESCFPFFGEGTEEEVLHLIQRGAKSGRVPELMHFQINSELDLLSLGTMTRRGS FPLPVSVSLSEELLYQYDALAEDLYRFQKWVISPSLFLKESEESWDDLLQFVSRFAKDKRSVEWTFSSTHIEQATVVLKE CKKRKIENILFSVSDGDLLSLRKLACLLQESDYPIVLNVSAKNKDQLMYDASIKAGGSLLDGIGDVIRLSFGDGEAEECL HLSFDILQATRLRLTKTEYISCPSCGRTMFDLQSTTAKIKEKTGHLKGVKIAVMGCIVNGPGEMADADFGYVGAGVGKVH LYKGKEIVKKGVSETEAPDLLIELIRENGMWNDPA
Sequences:
>Translated_675_residues MSTKYNESPFFYRRRPTREVKVGDVGIGGKNPIRVQSMITSNTRDTDASIQQIMDLERAGSEIVRLTVPSQADADNLPNI RKKMKELGLKVPLVADIHFTPQVALKCVEWVEKVRINPGNFADKKKFEIIEYTDNDYHEELARIEEVFTPLVLRAKELGV AMRIGTNHGSLSDRIMNRFGDTPLGMVESALEFIRIAEKNSYRDIVVSMKASNPQVMIQAYRMLVARFYDLGMDYPLHLG VTEAGDGKDGRIKSAIGIGSLLEDGLGDTVRVSLTEDAIHEIPVAKELVRKYNDLFFASLTTKENSIPKEREIIYTEFRD PYQYSRFYSKELMIGESKIGDSNPVRIESCFPFFGEGTEEEVLHLIQRGAKSGRVPELMHFQINSELDLLSLGTMTRRGS FPLPVSVSLSEELLYQYDALAEDLYRFQKWVISPSLFLKESEESWDDLLQFVSRFAKDKRSVEWTFSSTHIEQATVVLKE CKKRKIENILFSVSDGDLLSLRKLACLLQESDYPIVLNVSAKNKDQLMYDASIKAGGSLLDGIGDVIRLSFGDGEAEECL HLSFDILQATRLRLTKTEYISCPSCGRTMFDLQSTTAKIKEKTGHLKGVKIAVMGCIVNGPGEMADADFGYVGAGVGKVH LYKGKEIVKKGVSETEAPDLLIELIRENGMWNDPA >Mature_674_residues STKYNESPFFYRRRPTREVKVGDVGIGGKNPIRVQSMITSNTRDTDASIQQIMDLERAGSEIVRLTVPSQADADNLPNIR KKMKELGLKVPLVADIHFTPQVALKCVEWVEKVRINPGNFADKKKFEIIEYTDNDYHEELARIEEVFTPLVLRAKELGVA MRIGTNHGSLSDRIMNRFGDTPLGMVESALEFIRIAEKNSYRDIVVSMKASNPQVMIQAYRMLVARFYDLGMDYPLHLGV TEAGDGKDGRIKSAIGIGSLLEDGLGDTVRVSLTEDAIHEIPVAKELVRKYNDLFFASLTTKENSIPKEREIIYTEFRDP YQYSRFYSKELMIGESKIGDSNPVRIESCFPFFGEGTEEEVLHLIQRGAKSGRVPELMHFQINSELDLLSLGTMTRRGSF PLPVSVSLSEELLYQYDALAEDLYRFQKWVISPSLFLKESEESWDDLLQFVSRFAKDKRSVEWTFSSTHIEQATVVLKEC KKRKIENILFSVSDGDLLSLRKLACLLQESDYPIVLNVSAKNKDQLMYDASIKAGGSLLDGIGDVIRLSFGDGEAEECLH LSFDILQATRLRLTKTEYISCPSCGRTMFDLQSTTAKIKEKTGHLKGVKIAVMGCIVNGPGEMADADFGYVGAGVGKVHL YKGKEIVKKGVSETEAPDLLIELIRENGMWNDPA
Specific function: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate [H]
COG id: COG0821
COG function: function code I; Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ispG family [H]
Homologues:
Organism=Escherichia coli, GI1788863, Length=288, Percent_Identity=37.1527777777778, Blast_Score=182, Evalue=9e-47,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017178 - InterPro: IPR004588 [H]
Pfam domain/function: PF04551 GcpE [H]
EC number: =1.17.7.1 [H]
Molecular weight: Translated: 75877; Mature: 75746
Theoretical pI: Translated: 5.53; Mature: 5.53
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTKYNESPFFYRRRPTREVKVGDVGIGGKNPIRVQSMITSNTRDTDASIQQIMDLERAG CCCCCCCCCCEEECCCCCEEEECEECCCCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHCC SEIVRLTVPSQADADNLPNIRKKMKELGLKVPLVADIHFTPQVALKCVEWVEKVRINPGN CEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCC FADKKKFEIIEYTDNDYHEELARIEEVFTPLVLRAKELGVAMRIGTNHGSLSDRIMNRFG CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHC DTPLGMVESALEFIRIAEKNSYRDIVVSMKASNPQVMIQAYRMLVARFYDLGMDYPLHLG CCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEE VTEAGDGKDGRIKSAIGIGSLLEDGLGDTVRVSLTEDAIHEIPVAKELVRKYNDLFFASL EECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHCHHHHHHHHHHHHEEEEEE TTKENSIPKEREIIYTEFRDPYQYSRFYSKELMIGESKIGDSNPVRIESCFPFFGEGTEE ECCCCCCCCHHCEEEECCCCCHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCCCCHH EVLHLIQRGAKSGRVPELMHFQINSELDLLSLGTMTRRGSFPLPVSVSLSEELLYQYDAL HHHHHHHCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCEEEECCHHHHHHHHHHH AEDLYRFQKWVISPSLFLKESEESWDDLLQFVSRFAKDKRSVEWTFSSTHIEQATVVLKE HHHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH CKKRKIENILFSVSDGDLLSLRKLACLLQESDYPIVLNVSAKNKDQLMYDASIKAGGSLL HHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCCCHHH DGIGDVIRLSFGDGEAEECLHLSFDILQATRLRLTKTEYISCPSCGRTMFDLQSTTAKIK HCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHEEHHHEECCCCCCCHHHHHHHHHHHHH EKTGHLKGVKIAVMGCIVNGPGEMADADFGYVGAGVGKVHLYKGKEIVKKGVSETEAPDL HHCCCCCCEEEEEEEEEECCCCCCCCCCCCEEECCCCEEEEECCHHHHHCCCCCCCHHHH LIELIRENGMWNDPA HHHHHHHCCCCCCCC >Mature Secondary Structure STKYNESPFFYRRRPTREVKVGDVGIGGKNPIRVQSMITSNTRDTDASIQQIMDLERAG CCCCCCCCCEEECCCCCEEEECEECCCCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHCC SEIVRLTVPSQADADNLPNIRKKMKELGLKVPLVADIHFTPQVALKCVEWVEKVRINPGN CEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCC FADKKKFEIIEYTDNDYHEELARIEEVFTPLVLRAKELGVAMRIGTNHGSLSDRIMNRFG CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHC DTPLGMVESALEFIRIAEKNSYRDIVVSMKASNPQVMIQAYRMLVARFYDLGMDYPLHLG CCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEE VTEAGDGKDGRIKSAIGIGSLLEDGLGDTVRVSLTEDAIHEIPVAKELVRKYNDLFFASL EECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHCHHHHHHHHHHHHEEEEEE TTKENSIPKEREIIYTEFRDPYQYSRFYSKELMIGESKIGDSNPVRIESCFPFFGEGTEE ECCCCCCCCHHCEEEECCCCCHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCCCCHH EVLHLIQRGAKSGRVPELMHFQINSELDLLSLGTMTRRGSFPLPVSVSLSEELLYQYDAL HHHHHHHCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCEEEECCHHHHHHHHHHH AEDLYRFQKWVISPSLFLKESEESWDDLLQFVSRFAKDKRSVEWTFSSTHIEQATVVLKE HHHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH CKKRKIENILFSVSDGDLLSLRKLACLLQESDYPIVLNVSAKNKDQLMYDASIKAGGSLL HHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCCCHHH DGIGDVIRLSFGDGEAEECLHLSFDILQATRLRLTKTEYISCPSCGRTMFDLQSTTAKIK HCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHEEHHHEECCCCCCCHHHHHHHHHHHHH EKTGHLKGVKIAVMGCIVNGPGEMADADFGYVGAGVGKVHLYKGKEIVKKGVSETEAPDL HHCCCCCCEEEEEEEEEECCCCCCCCCCCCEEECCCCEEEEECCHHHHHCCCCCCCHHHH LIELIRENGMWNDPA HHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA