| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is kinE [H]
Identifier: 183220596
GI number: 183220596
Start: 1251629
End: 1253863
Strand: Reverse
Name: kinE [H]
Synonym: LEPBI_I1200
Alternate gene names: 183220596
Gene position: 1253863-1251629 (Counterclockwise)
Preceding gene: 183220598
Following gene: 183220592
Centisome position: 34.83
GC content: 34.81
Gene sequence:
>2235_bases ATGAAGGTATATATAAAGATCATATTATTCTTTAGTTTCACCTTCTTCTCTTTTTGTACTCCGCAAAAGAACACTCTCCC CCATATCATACATGGAAATTTAGATTTAAGACAAATTGACATTCAGAAATATCCTAACTTCCCTTTGCATGGAGAATGGA GGTTCTCGCCTGGTGTTTTCCAATTCGAAACCTCGGAGGGAAGCCATTTGGTTTCCATTCCTGAAAATTCGAATTGGAAT GATTCTATTGGGAATAAAAACAAGGATGGATTCGGAATTGGTACATACCAAATCACTATCCAATTACCAGAAAACACGCC TAAGCTTGCCATCCATTTGGTCGCCATGCATTCGGATTGCCAAATTTTCCAAGATTCAGAACAAATTGGTGAATTTGGTT CGATCGATGACGAATCAAGTTCTTTTGAAAAAATGCCGCGAGTGTTTTCACTGAAACCAACGGAACAATCCACTATCAAA CTTACATTACTAATCAAAAACCGTTTTTACAAATATGGTGGGATCCGGATTCCTCCCATTTTTGGATTGGAAGAATCCAT CCAAGAAAACATTCGCATTTCAATCTTACAAGAGGCGCTCCTTGCTGGTGGATTGGTATTTTTAGGTTTGTACCAATTAG GCATCTACTTTACGAGAAAAAAAGTCATAGGATCTTTATACTTCTTTCTGTTTTGTATTTTGATGTTTTTCCAAATCCTA TCGACTGGATCACAAAGTTTATTTTTGGTTGTAGGCAAAGAGATGGGTGAATTGGTCTATCGAACGGATTTATTCACGGA ATATGCAGGAGTGATTGCAGGACTATTTTATATCCATTGTTTAACGAAAGAATACATCCCTCAAAAATTCATCTATGGAT ATTCCTTACTCATTCTGATTCCGATCCTAAACACGATATTGGGAAGCCTACAATCCATCAGTCGTTATCATTTTATCGTT TTAGGATTGATCATTCCAATTTTAATCGTACTTTTTTATTTAATCTTTTGTTACATAAAAGACAAACGATCAGGATTTAT CTACTTAGGGCTTTCTGTTATTTTTTTGATTGGAGCCGCAACAAATGATATCATCCACACCTTACTTCATAAAACAGAGC CATCATTTTTAAATATTGGATTATTATTATTTGTATTTTTCCAATCACTCTTTTTGTCGAAACACATCTCAGGCGAAATT GTCTCTGCAGAAATAAAATTCAAAGATGTTCTTTTCCAACTGATCCAATCCGAAAAACTTTCTTCGATAGGAATGACGGT CACAAGTGTCGCACATGAAATCAACTCTCCATTAAGTGCAGTCATCTTAACAAGTGATTCCATTCGAGACAATATCTCAG ACTTTTTTAGACAACTTCCCGAATTAGAATCTATTTCTAAAAAAAGTTTTCCTTTTGTACTTTCTCTCATAGAACATGCT ATGACCGAACAAAGTTTACCAACCGGTTTAGAATTTAGACAAAAAAAGGGAATCTTCCTCAGTGAATTAGAAAAACACCA AATCTTATATTCTGATCAATATGCGGAGATATTTGTAACTCTTGGAATTTTGGAAATTCCACAAGACTGGATCCAATTAT TAAGCCAATACAATTCAAAATCCTTAGTATTACTCGCAGAAAAAATAGTGAATATCTTACTTGGAACAAATGCGATTCAA ACTTCTGCGAACCGCGCGATCAAAATTGCACAAGCACTTAAAAACTTCACACATTTCGATCCCAAAGCTGAAATCAAAAC CATCCAACTCTCGGATTCCTTACATCAGATCCTTACAATTTTGCAAGGATCATTAAAACATGGAGTTGAATTAAAAACAA ATTTTGTAAACATACCTCCCATCAATTGTTATCCAGATGAACTCAATCAAGTTTGGACCAATATGATTCAGAATGCGATC CAATCAATGAATGGAAAAGGAAATCTTACAATCGAAATCAATCAAACTGTATTAAAAAATAATCCATTTGCCTATGTCAG CATTGAAGATTCGGGGCCAGGGGTATCAAAAGAAATTTTAGACAAAATTTTTGATCCTTTTTTTACAACAAAACCAATTG GACAAGGGACTGGCCTCGGCCTCTACATTTCCAAACAAATCATTGAAAAACATAAAGGGATCATCGATGTGATCTCTACG AAAGGGAATACTAAATTCATTGTTTATTTGCCTTACCTTGACAAAACAAACGTTATCAAAAATGAATCAGTTTGA
Upstream 100 bases:
>100_bases AATTCAAGATATAAAAGAAAGTGTTAAAATAAACTTGACCTATTCTAAAAATAGAATCAGTTAAGGTGCAATTTCTGAAG GAAATATTTTCTTAACAAAC
Downstream 100 bases:
>100_bases CATTTCCATTTTTAGGGATGTATTAAACGGGATCAGGTAATCGAAAACTAACAGTTGTTCCTTTCCCTTTTTCACTTTTA GCCCAGATTTCACCACCATG
Product: putative signal transduction histidine kinase
Products: NA
Alternate protein names: Sensor histidine kinase E [H]
Number of amino acids: Translated: 744; Mature: 744
Protein sequence:
>744_residues MKVYIKIILFFSFTFFSFCTPQKNTLPHIIHGNLDLRQIDIQKYPNFPLHGEWRFSPGVFQFETSEGSHLVSIPENSNWN DSIGNKNKDGFGIGTYQITIQLPENTPKLAIHLVAMHSDCQIFQDSEQIGEFGSIDDESSSFEKMPRVFSLKPTEQSTIK LTLLIKNRFYKYGGIRIPPIFGLEESIQENIRISILQEALLAGGLVFLGLYQLGIYFTRKKVIGSLYFFLFCILMFFQIL STGSQSLFLVVGKEMGELVYRTDLFTEYAGVIAGLFYIHCLTKEYIPQKFIYGYSLLILIPILNTILGSLQSISRYHFIV LGLIIPILIVLFYLIFCYIKDKRSGFIYLGLSVIFLIGAATNDIIHTLLHKTEPSFLNIGLLLFVFFQSLFLSKHISGEI VSAEIKFKDVLFQLIQSEKLSSIGMTVTSVAHEINSPLSAVILTSDSIRDNISDFFRQLPELESISKKSFPFVLSLIEHA MTEQSLPTGLEFRQKKGIFLSELEKHQILYSDQYAEIFVTLGILEIPQDWIQLLSQYNSKSLVLLAEKIVNILLGTNAIQ TSANRAIKIAQALKNFTHFDPKAEIKTIQLSDSLHQILTILQGSLKHGVELKTNFVNIPPINCYPDELNQVWTNMIQNAI QSMNGKGNLTIEINQTVLKNNPFAYVSIEDSGPGVSKEILDKIFDPFFTTKPIGQGTGLGLYISKQIIEKHKGIIDVIST KGNTKFIVYLPYLDKTNVIKNESV
Sequences:
>Translated_744_residues MKVYIKIILFFSFTFFSFCTPQKNTLPHIIHGNLDLRQIDIQKYPNFPLHGEWRFSPGVFQFETSEGSHLVSIPENSNWN DSIGNKNKDGFGIGTYQITIQLPENTPKLAIHLVAMHSDCQIFQDSEQIGEFGSIDDESSSFEKMPRVFSLKPTEQSTIK LTLLIKNRFYKYGGIRIPPIFGLEESIQENIRISILQEALLAGGLVFLGLYQLGIYFTRKKVIGSLYFFLFCILMFFQIL STGSQSLFLVVGKEMGELVYRTDLFTEYAGVIAGLFYIHCLTKEYIPQKFIYGYSLLILIPILNTILGSLQSISRYHFIV LGLIIPILIVLFYLIFCYIKDKRSGFIYLGLSVIFLIGAATNDIIHTLLHKTEPSFLNIGLLLFVFFQSLFLSKHISGEI VSAEIKFKDVLFQLIQSEKLSSIGMTVTSVAHEINSPLSAVILTSDSIRDNISDFFRQLPELESISKKSFPFVLSLIEHA MTEQSLPTGLEFRQKKGIFLSELEKHQILYSDQYAEIFVTLGILEIPQDWIQLLSQYNSKSLVLLAEKIVNILLGTNAIQ TSANRAIKIAQALKNFTHFDPKAEIKTIQLSDSLHQILTILQGSLKHGVELKTNFVNIPPINCYPDELNQVWTNMIQNAI QSMNGKGNLTIEINQTVLKNNPFAYVSIEDSGPGVSKEILDKIFDPFFTTKPIGQGTGLGLYISKQIIEKHKGIIDVIST KGNTKFIVYLPYLDKTNVIKNESV >Mature_744_residues MKVYIKIILFFSFTFFSFCTPQKNTLPHIIHGNLDLRQIDIQKYPNFPLHGEWRFSPGVFQFETSEGSHLVSIPENSNWN DSIGNKNKDGFGIGTYQITIQLPENTPKLAIHLVAMHSDCQIFQDSEQIGEFGSIDDESSSFEKMPRVFSLKPTEQSTIK LTLLIKNRFYKYGGIRIPPIFGLEESIQENIRISILQEALLAGGLVFLGLYQLGIYFTRKKVIGSLYFFLFCILMFFQIL STGSQSLFLVVGKEMGELVYRTDLFTEYAGVIAGLFYIHCLTKEYIPQKFIYGYSLLILIPILNTILGSLQSISRYHFIV LGLIIPILIVLFYLIFCYIKDKRSGFIYLGLSVIFLIGAATNDIIHTLLHKTEPSFLNIGLLLFVFFQSLFLSKHISGEI VSAEIKFKDVLFQLIQSEKLSSIGMTVTSVAHEINSPLSAVILTSDSIRDNISDFFRQLPELESISKKSFPFVLSLIEHA MTEQSLPTGLEFRQKKGIFLSELEKHQILYSDQYAEIFVTLGILEIPQDWIQLLSQYNSKSLVLLAEKIVNILLGTNAIQ TSANRAIKIAQALKNFTHFDPKAEIKTIQLSDSLHQILTILQGSLKHGVELKTNFVNIPPINCYPDELNQVWTNMIQNAI QSMNGKGNLTIEINQTVLKNNPFAYVSIEDSGPGVSKEILDKIFDPFFTTKPIGQGTGLGLYISKQIIEKHKGIIDVIST KGNTKFIVYLPYLDKTNVIKNESV
Specific function: Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 4 PAS (PER-ARNT-SIM) domains [H]
Homologues:
Organism=Escherichia coli, GI1788549, Length=171, Percent_Identity=34.5029239766082, Blast_Score=85, Evalue=1e-17, Organism=Escherichia coli, GI1790436, Length=139, Percent_Identity=35.2517985611511, Blast_Score=85, Evalue=2e-17, Organism=Escherichia coli, GI1790300, Length=230, Percent_Identity=26.9565217391304, Blast_Score=83, Evalue=5e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR000014 - InterPro: IPR013767 - InterPro: IPR004358 - InterPro: IPR003661 - InterPro: IPR005467 - InterPro: IPR009082 [H]
Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 84162; Mature: 84162
Theoretical pI: Translated: 7.15; Mature: 7.15
Prosite motif: PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKVYIKIILFFSFTFFSFCTPQKNTLPHIIHGNLDLRQIDIQKYPNFPLHGEWRFSPGVF CEEEEEHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEHHHCCCCCCCCEEEECCCEE QFETSEGSHLVSIPENSNWNDSIGNKNKDGFGIGTYQITIQLPENTPKLAIHLVAMHSDC EEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEEECCCC QIFQDSEQIGEFGSIDDESSSFEKMPRVFSLKPTEQSTIKLTLLIKNRFYKYGGIRIPPI CEECCHHHHCCCCCCCCCCHHHHHCCCEEECCCCCCCEEEEEEEEECCHHHCCCEECCCC FGLEESIQENIRISILQEALLAGGLVFLGLYQLGIYFTRKKVIGSLYFFLFCILMFFQIL CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH STGSQSLFLVVGKEMGELVYRTDLFTEYAGVIAGLFYIHCLTKEYIPQKFIYGYSLLILI HCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH PILNTILGSLQSISRYHFIVLGLIIPILIVLFYLIFCYIKDKRSGFIYLGLSVIFLIGAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCC TNDIIHTLLHKTEPSFLNIGLLLFVFFQSLFLSKHISGEIVSAEIKFKDVLFQLIQSEKL HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH SSIGMTVTSVAHEINSPLSAVILTSDSIRDNISDFFRQLPELESISKKSFPFVLSLIEHA HHHCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH MTEQSLPTGLEFRQKKGIFLSELEKHQILYSDQYAEIFVTLGILEIPQDWIQLLSQYNSK HHHCCCCCCCHHHHHCCCHHHHHHHHHHEECCHHHHHHHHHHHHHCCHHHHHHHHHCCCC SLVLLAEKIVNILLGTNAIQTSANRAIKIAQALKNFTHFDPKAEIKTIQLSDSLHQILTI EEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHH LQGSLKHGVELKTNFVNIPPINCYPDELNQVWTNMIQNAIQSMNGKGNLTIEINQTVLKN HHHHHHCCCEEEECEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEECC NPFAYVSIEDSGPGVSKEILDKIFDPFFTTKPIGQGTGLGLYISKQIIEKHKGIIDVIST CCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEC KGNTKFIVYLPYLDKTNVIKNESV CCCEEEEEEEECCCCCCCCCCCCC >Mature Secondary Structure MKVYIKIILFFSFTFFSFCTPQKNTLPHIIHGNLDLRQIDIQKYPNFPLHGEWRFSPGVF CEEEEEHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEHHHCCCCCCCCEEEECCCEE QFETSEGSHLVSIPENSNWNDSIGNKNKDGFGIGTYQITIQLPENTPKLAIHLVAMHSDC EEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEEECCCC QIFQDSEQIGEFGSIDDESSSFEKMPRVFSLKPTEQSTIKLTLLIKNRFYKYGGIRIPPI CEECCHHHHCCCCCCCCCCHHHHHCCCEEECCCCCCCEEEEEEEEECCHHHCCCEECCCC FGLEESIQENIRISILQEALLAGGLVFLGLYQLGIYFTRKKVIGSLYFFLFCILMFFQIL CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH STGSQSLFLVVGKEMGELVYRTDLFTEYAGVIAGLFYIHCLTKEYIPQKFIYGYSLLILI HCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH PILNTILGSLQSISRYHFIVLGLIIPILIVLFYLIFCYIKDKRSGFIYLGLSVIFLIGAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCC TNDIIHTLLHKTEPSFLNIGLLLFVFFQSLFLSKHISGEIVSAEIKFKDVLFQLIQSEKL HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH SSIGMTVTSVAHEINSPLSAVILTSDSIRDNISDFFRQLPELESISKKSFPFVLSLIEHA HHHCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH MTEQSLPTGLEFRQKKGIFLSELEKHQILYSDQYAEIFVTLGILEIPQDWIQLLSQYNSK HHHCCCCCCCHHHHHCCCHHHHHHHHHHEECCHHHHHHHHHHHHHCCHHHHHHHHHCCCC SLVLLAEKIVNILLGTNAIQTSANRAIKIAQALKNFTHFDPKAEIKTIQLSDSLHQILTI EEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHH LQGSLKHGVELKTNFVNIPPINCYPDELNQVWTNMIQNAIQSMNGKGNLTIEINQTVLKN HHHHHHCCCEEEECEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEECC NPFAYVSIEDSGPGVSKEILDKIFDPFFTTKPIGQGTGLGLYISKQIIEKHKGIIDVIST CCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEC KGNTKFIVYLPYLDKTNVIKNESV CCCEEEEEEEECCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]