| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is slt [H]
Identifier: 183220447
GI number: 183220447
Start: 1085476
End: 1087743
Strand: Reverse
Name: slt [H]
Synonym: LEPBI_I1044
Alternate gene names: 183220447
Gene position: 1087743-1085476 (Counterclockwise)
Preceding gene: 183220455
Following gene: 183220446
Centisome position: 30.22
GC content: 40.26
Gene sequence:
>2268_bases ATGAGGCATTTTTGGTTAGCAAGTAGAATTCTTCTCTTTTTCACAACATCCCTACTTGCCGAAACAGACCTTCATTATTT GATCAAATCCCACCAATGGGGGCAAATTGAAAACCATTTCAAAAACTCCACTCCTTCCCGGGAAAGTGAAGTGTACACTC TCATTGAATTCCATGAAAAATCACCTAACGGAGACAAGGAGAAACGATTTCGTTATTTATTATCTCTGATCCGCGGAGTG TTTGTGACAGATGCAAACGAGGAAGAAGTCAAAAAGATTCTCACCCAAACCATGCCTTTCCAAACCACGCTTTTTAAATT GAGTTATTGGAAATTGTACAATGAAATAACTGCTAAAAATTTTCTCACTCCTCAGGAGAGAATCCAATTCTTAAATCGAT TGAATATGGAAGAGGATCCCATTTGCCGCAGGGCCTTGGATGAACAAATTAGATTGTTAGCAGCAAACAACCAATGGAAG GAAATCATAGAAAAAATCCAATCCATCCAAGATTCTCACAAAAGGTATCTTCTAACAGGAGATAGTTTGTATCGATTGGG AAAAGCGAAATTGATCTTAGGTGATGAAAAAGCTGCCATCGAAGATTGGCTCAATTGTTTACAAAAAGAAGGCTTAATGG ACCAAACCGTGCAAATGATTGCATCGGATTGGAGTAAATACAAAGGTAGTGGCAGTATCTTACAACTTGGCCCTTCTGAA CTCACTTTATTTTTACCTGCCATCAATTCAAATGACAAGGAGGCGCTCTTTCGTTCAAGGCCTGAACTTTTTTCCAGTCG ATTGAATTATTATGAAGGGTTTAAACACCTAACACAAGTTTTAACCAAAGTGGGAAAAACCAATGAACTCTTCCGAGTGT TACGCGCCAATAAAAGTTTTGTGGATATGGATTCCTCGTGGATTGTGACCCTTGCCGATACCTTATACCAACAAAATAAA TTCCAACAGGCAATTGAACTCCTAAAAACCTTTCCGGGAAAAGACGCAGGGTATTACCGAGTGCTTGCGGCTTCTTACGA CCGTTTGGGGGATAAGGAATTATACTTTGAAAACTTGATTTTATACTTAGGAAAGTATCCATTCAATTTATTTTACCAAG ACCGACTGATTGAATATCTCGTCGAACGCAAAGGGGAAAAATCACGATATGCTCCCCTTGTTAAATTTGAAAGGGCCCTT GCGGAGATCCCAAACCTACCTGTCAAAGGAAGGCTTGTGTATTGGTATTTACGTTCTCTTAAAGAAAATGGAGAAACCGA TCGTCTCAAAAAAGAATTAAAACGATACTACGCACTTTGCCCAGGTTCTTACTACACACGTGTGATCCGTGAAGAATTTT TATCCACAATCAAAGAATCCAATAAACCAGAAAACCCAACCTATAACAAAGAATACCTCTTTGAATATTTATCCTATACA GCAGGCATCCCAGAAGAATCGGGGGCACTCATTGGTCGCAATTTAGGATTTGTATACCCAAAAGATTCGTATGAACTGGG AAACAAATTGGGGGGAATGAGTTCAAGAATCCAAGGTCACAAACTCTTAAACCTTGCCAAAGAATACTTCCGCGTGGGAG AAGATAGTTTAGGCCTCCACTTAGTAAACTTCCACGTAAAACGAGAAAATCTTTCGGAAGATGAGAAGGATGAAATCCTT GTTGGGATTGGGGATCTCACGCGTAACACCTATTATTCGGCATTTCATACACGTTCCCTTCTCAAACGATACCTCATTCC AGATGATCCCATTTTACTGCCCACTTCCCTTTCGGTTCGAATGTATCCAAGACCTCACCAAACGATTGTCGCACGTTATG CCAATGAAAACGGAATCCCTGAAGACAATGTGTATGCCTTGATGCGACAAGAATCTTTTTTTAAAGAAACGGCTACCTCC AGGTCAAATGCCCGAGGCCTCATGCAAATCATGCCTGCGACGGGACGAGAGCTTGCCCAAAGGATGGGGGTCACTTCTTA TTCTCTCTATGAACCAGAAACATCCATCAGACTCGGAACAAAATTTTTGGCCTACCTTCTCAAATCCAATGGGAACGAAT TAAAATGGGCATCCATCGCCTACAACGGTGGGCCTGGGAATTTACGAAAATGGAAAAAATCTGTCTACACGGGTGATTTT AACCATTTTTTAGAAGACTTACCATACAAAGAATCAAGAGACTATTGTCGCATCGTTGTTTCGAATTTCTACGCATACGA TATCATGAAAAAATACCATAAGTTGTAA
Upstream 100 bases:
>100_bases ATTCGATTCTATATTCTGGCCAGCGCAGTTTGTATTCTGTTTGTGAGCTCATAAGGAGGGGGACCTTCCCTCTCTAAATT CGTAATCATAGGAAGTATGC
Downstream 100 bases:
>100_bases AAAATGGCTTTTCCCCTCCCTTTCCCCTGTCTATTCTTTGAAATAGACAGAGATATACAGGAGAAGATATGTCCGAAAAG GCAATTCTGAAAGTGGATGG
Product: soluble lytic murein transglycosylase
Products: 1,6-Anhydrobond [C]
Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]
Number of amino acids: Translated: 755; Mature: 755
Protein sequence:
>755_residues MRHFWLASRILLFFTTSLLAETDLHYLIKSHQWGQIENHFKNSTPSRESEVYTLIEFHEKSPNGDKEKRFRYLLSLIRGV FVTDANEEEVKKILTQTMPFQTTLFKLSYWKLYNEITAKNFLTPQERIQFLNRLNMEEDPICRRALDEQIRLLAANNQWK EIIEKIQSIQDSHKRYLLTGDSLYRLGKAKLILGDEKAAIEDWLNCLQKEGLMDQTVQMIASDWSKYKGSGSILQLGPSE LTLFLPAINSNDKEALFRSRPELFSSRLNYYEGFKHLTQVLTKVGKTNELFRVLRANKSFVDMDSSWIVTLADTLYQQNK FQQAIELLKTFPGKDAGYYRVLAASYDRLGDKELYFENLILYLGKYPFNLFYQDRLIEYLVERKGEKSRYAPLVKFERAL AEIPNLPVKGRLVYWYLRSLKENGETDRLKKELKRYYALCPGSYYTRVIREEFLSTIKESNKPENPTYNKEYLFEYLSYT AGIPEESGALIGRNLGFVYPKDSYELGNKLGGMSSRIQGHKLLNLAKEYFRVGEDSLGLHLVNFHVKRENLSEDEKDEIL VGIGDLTRNTYYSAFHTRSLLKRYLIPDDPILLPTSLSVRMYPRPHQTIVARYANENGIPEDNVYALMRQESFFKETATS RSNARGLMQIMPATGRELAQRMGVTSYSLYEPETSIRLGTKFLAYLLKSNGNELKWASIAYNGGPGNLRKWKKSVYTGDF NHFLEDLPYKESRDYCRIVVSNFYAYDIMKKYHKL
Sequences:
>Translated_755_residues MRHFWLASRILLFFTTSLLAETDLHYLIKSHQWGQIENHFKNSTPSRESEVYTLIEFHEKSPNGDKEKRFRYLLSLIRGV FVTDANEEEVKKILTQTMPFQTTLFKLSYWKLYNEITAKNFLTPQERIQFLNRLNMEEDPICRRALDEQIRLLAANNQWK EIIEKIQSIQDSHKRYLLTGDSLYRLGKAKLILGDEKAAIEDWLNCLQKEGLMDQTVQMIASDWSKYKGSGSILQLGPSE LTLFLPAINSNDKEALFRSRPELFSSRLNYYEGFKHLTQVLTKVGKTNELFRVLRANKSFVDMDSSWIVTLADTLYQQNK FQQAIELLKTFPGKDAGYYRVLAASYDRLGDKELYFENLILYLGKYPFNLFYQDRLIEYLVERKGEKSRYAPLVKFERAL AEIPNLPVKGRLVYWYLRSLKENGETDRLKKELKRYYALCPGSYYTRVIREEFLSTIKESNKPENPTYNKEYLFEYLSYT AGIPEESGALIGRNLGFVYPKDSYELGNKLGGMSSRIQGHKLLNLAKEYFRVGEDSLGLHLVNFHVKRENLSEDEKDEIL VGIGDLTRNTYYSAFHTRSLLKRYLIPDDPILLPTSLSVRMYPRPHQTIVARYANENGIPEDNVYALMRQESFFKETATS RSNARGLMQIMPATGRELAQRMGVTSYSLYEPETSIRLGTKFLAYLLKSNGNELKWASIAYNGGPGNLRKWKKSVYTGDF NHFLEDLPYKESRDYCRIVVSNFYAYDIMKKYHKL >Mature_755_residues MRHFWLASRILLFFTTSLLAETDLHYLIKSHQWGQIENHFKNSTPSRESEVYTLIEFHEKSPNGDKEKRFRYLLSLIRGV FVTDANEEEVKKILTQTMPFQTTLFKLSYWKLYNEITAKNFLTPQERIQFLNRLNMEEDPICRRALDEQIRLLAANNQWK EIIEKIQSIQDSHKRYLLTGDSLYRLGKAKLILGDEKAAIEDWLNCLQKEGLMDQTVQMIASDWSKYKGSGSILQLGPSE LTLFLPAINSNDKEALFRSRPELFSSRLNYYEGFKHLTQVLTKVGKTNELFRVLRANKSFVDMDSSWIVTLADTLYQQNK FQQAIELLKTFPGKDAGYYRVLAASYDRLGDKELYFENLILYLGKYPFNLFYQDRLIEYLVERKGEKSRYAPLVKFERAL AEIPNLPVKGRLVYWYLRSLKENGETDRLKKELKRYYALCPGSYYTRVIREEFLSTIKESNKPENPTYNKEYLFEYLSYT AGIPEESGALIGRNLGFVYPKDSYELGNKLGGMSSRIQGHKLLNLAKEYFRVGEDSLGLHLVNFHVKRENLSEDEKDEIL VGIGDLTRNTYYSAFHTRSLLKRYLIPDDPILLPTSLSVRMYPRPHQTIVARYANENGIPEDNVYALMRQESFFKETATS RSNARGLMQIMPATGRELAQRMGVTSYSLYEPETSIRLGTKFLAYLLKSNGNELKWASIAYNGGPGNLRKWKKSVYTGDF NHFLEDLPYKESRDYCRIVVSNFYAYDIMKKYHKL
Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]
COG id: COG0741
COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Gene ontology:
Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI87082441, Length=156, Percent_Identity=35.8974358974359, Blast_Score=96, Evalue=9e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016026 - InterPro: IPR008258 - InterPro: IPR012289 - InterPro: IPR008939 - InterPro: IPR000189 [H]
Pfam domain/function: PF01464 SLT [H]
EC number: 3.2.1.- [C]
Molecular weight: Translated: 88171; Mature: 88171
Theoretical pI: Translated: 9.36; Mature: 9.36
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRHFWLASRILLFFTTSLLAETDLHYLIKSHQWGQIENHFKNSTPSRESEVYTLIEFHEK CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHEEEEEEECC SPNGDKEKRFRYLLSLIRGVFVTDANEEEVKKILTQTMPFQTTLFKLSYWKLYNEITAKN CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH FLTPQERIQFLNRLNMEEDPICRRALDEQIRLLAANNQWKEIIEKIQSIQDSHKRYLLTG CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEC DSLYRLGKAKLILGDEKAAIEDWLNCLQKEGLMDQTVQMIASDWSKYKGSGSILQLGPSE HHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCC LTLFLPAINSNDKEALFRSRPELFSSRLNYYEGFKHLTQVLTKVGKTNELFRVLRANKSF EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCE VDMDSSWIVTLADTLYQQNKFQQAIELLKTFPGKDAGYYRVLAASYDRLGDKELYFENLI EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHH LYLGKYPFNLFYQDRLIEYLVERKGEKSRYAPLVKFERALAEIPNLPVKGRLVYWYLRSL HHHHCCCCHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH KENGETDRLKKELKRYYALCPGSYYTRVIREEFLSTIKESNKPENPTYNKEYLFEYLSYT HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH AGIPEESGALIGRNLGFVYPKDSYELGNKLGGMSSRIQGHKLLNLAKEYFRVGEDSLGLH CCCCCCCCCEEECCCCEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE LVNFHVKRENLSEDEKDEILVGIGDLTRNTYYSAFHTRSLLKRYLIPDDPILLPTSLSVR EEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEE MYPRPHQTIVARYANENGIPEDNVYALMRQESFFKETATSRSNARGLMQIMPATGRELAQ ECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHH RMGVTSYSLYEPETSIRLGTKFLAYLLKSNGNELKWASIAYNGGPGNLRKWKKSVYTGDF HCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCH NHFLEDLPYKESRDYCRIVVSNFYAYDIMKKYHKL HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MRHFWLASRILLFFTTSLLAETDLHYLIKSHQWGQIENHFKNSTPSRESEVYTLIEFHEK CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHEEEEEEECC SPNGDKEKRFRYLLSLIRGVFVTDANEEEVKKILTQTMPFQTTLFKLSYWKLYNEITAKN CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH FLTPQERIQFLNRLNMEEDPICRRALDEQIRLLAANNQWKEIIEKIQSIQDSHKRYLLTG CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEC DSLYRLGKAKLILGDEKAAIEDWLNCLQKEGLMDQTVQMIASDWSKYKGSGSILQLGPSE HHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCC LTLFLPAINSNDKEALFRSRPELFSSRLNYYEGFKHLTQVLTKVGKTNELFRVLRANKSF EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCE VDMDSSWIVTLADTLYQQNKFQQAIELLKTFPGKDAGYYRVLAASYDRLGDKELYFENLI EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHH LYLGKYPFNLFYQDRLIEYLVERKGEKSRYAPLVKFERALAEIPNLPVKGRLVYWYLRSL HHHHCCCCHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH KENGETDRLKKELKRYYALCPGSYYTRVIREEFLSTIKESNKPENPTYNKEYLFEYLSYT HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH AGIPEESGALIGRNLGFVYPKDSYELGNKLGGMSSRIQGHKLLNLAKEYFRVGEDSLGLH CCCCCCCCCEEECCCCEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE LVNFHVKRENLSEDEKDEILVGIGDLTRNTYYSAFHTRSLLKRYLIPDDPILLPTSLSVR EEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEE MYPRPHQTIVARYANENGIPEDNVYALMRQESFFKETATSRSNARGLMQIMPATGRELAQ ECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHH RMGVTSYSLYEPETSIRLGTKFLAYLLKSNGNELKWASIAYNGGPGNLRKWKKSVYTGDF HCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCH NHFLEDLPYKESRDYCRIVVSNFYAYDIMKKYHKL HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]
Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]
General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]