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The map label for this gene is nadA [H]

Identifier: 183219745

GI number: 183219745

Start: 320886

End: 321872

Strand: Direct

Name: nadA [H]

Synonym: LEPBI_I0321

Alternate gene names: 183219745

Gene position: 320886-321872 (Clockwise)

Preceding gene: 183219744

Following gene: 183219746

Centisome position: 8.91

GC content: 41.84

Gene sequence:

>987_bases
ATGTCACTCGTATCCAAAGACCAATTGGTCCAAAAATTAAAACCGATTTACCTTCCTCATGAAATTGAAGAACGAATCCT
TCCCCTCGCAGAAGAAATAGGTCGTCTCAAAAAAGAAAAAAATGCTGTGATCCTTGGTCACAATTATATGACTCCGGATG
TGTTTTGGGGAGTATCCGATATCATCGGAGATTCATTGTATCTTTCCAAAATGGCCAAAGAAACAACTGCGAATATGATT
TTGTTCAACGGGGTTCATTTTATGGCGGAAACTGCCAAAATCCTTTCCCCGGAGAAAAAGGTTCTCATCGCAGATCCAAA
AGCTGGGTGTTCCTTAGCAGAATCCATCACTCGAGAGGATGTGAAGGTCTTGAAAGCGAAATACCCGGGTGTACCCGTTG
TGACGTATGTCAACTGTTCGGCGGAAGTCAAAGCGGAAACAGATGTTTGTTGTACCTCTGCCAATGCCGTACAAATTGTG
AATGCGGTCGAAGGGGATACGGTTATCTTTTTGCCTGATGAATATTTGGCTGGGAATGTTCGTAACCAAACCTCAAAAAC
CATCATCTCTCATCCTGGTCGGTGTATGGTGCACGAAATATACACTCCAGAAGACATCCGTTCCACAAAACGCCTGTTCC
CTGGTGGTGTCACTGTCATCACTCACCCAGAATGCCATGAAGATGTAGTGAAAGAAGCTGATTTTTCTGGTTCAACCTCT
CAAATGGTGGATTTCATTCGGAACAGTAAAACGGACAAAATTATGCTTGTGACAGAGTGTTCGATGGGAGATAATTTACG
GTCTGAATTCCCTGAAAAAGAATTTGTCTCCACCTGCCAAACCTGTCCTCATATGAAAAAAATTACTTTGGAAAAAGTAA
GAGATGCCCTTTTGAAGGAACAGTTTGAAATCTTTTTGGACGAGGAAGTGATTCGCCTTGCCCAAAAATCTGTGAATCGT
ATGTTAGAGTTGAGTTATAAAAAATAA

Upstream 100 bases:

>100_bases
TCATTAGAGAATTCCGTTCCACCCGTTGATTCGGGACTTCAGGACACTGATACCATTCTTGGATCAGATCCTTTCCAATG
AATGTTATAAGGAGATAAAA

Downstream 100 bases:

>100_bases
TATGTTTAGAGTCGGAAACGGAATCGATTTTCATAAATTAATCCATGAACCCTTTCGCCCCCTTGTGCTTGCGGGAGTTG
AGATTAAATCAGAGTTTGCC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSLVSKDQLVQKLKPIYLPHEIEERILPLAEEIGRLKKEKNAVILGHNYMTPDVFWGVSDIIGDSLYLSKMAKETTANMI
LFNGVHFMAETAKILSPEKKVLIADPKAGCSLAESITREDVKVLKAKYPGVPVVTYVNCSAEVKAETDVCCTSANAVQIV
NAVEGDTVIFLPDEYLAGNVRNQTSKTIISHPGRCMVHEIYTPEDIRSTKRLFPGGVTVITHPECHEDVVKEADFSGSTS
QMVDFIRNSKTDKIMLVTECSMGDNLRSEFPEKEFVSTCQTCPHMKKITLEKVRDALLKEQFEIFLDEEVIRLAQKSVNR
MLELSYKK

Sequences:

>Translated_328_residues
MSLVSKDQLVQKLKPIYLPHEIEERILPLAEEIGRLKKEKNAVILGHNYMTPDVFWGVSDIIGDSLYLSKMAKETTANMI
LFNGVHFMAETAKILSPEKKVLIADPKAGCSLAESITREDVKVLKAKYPGVPVVTYVNCSAEVKAETDVCCTSANAVQIV
NAVEGDTVIFLPDEYLAGNVRNQTSKTIISHPGRCMVHEIYTPEDIRSTKRLFPGGVTVITHPECHEDVVKEADFSGSTS
QMVDFIRNSKTDKIMLVTECSMGDNLRSEFPEKEFVSTCQTCPHMKKITLEKVRDALLKEQFEIFLDEEVIRLAQKSVNR
MLELSYKK
>Mature_327_residues
SLVSKDQLVQKLKPIYLPHEIEERILPLAEEIGRLKKEKNAVILGHNYMTPDVFWGVSDIIGDSLYLSKMAKETTANMIL
FNGVHFMAETAKILSPEKKVLIADPKAGCSLAESITREDVKVLKAKYPGVPVVTYVNCSAEVKAETDVCCTSANAVQIVN
AVEGDTVIFLPDEYLAGNVRNQTSKTIISHPGRCMVHEIYTPEDIRSTKRLFPGGVTVITHPECHEDVVKEADFSGSTSQ
MVDFIRNSKTDKIMLVTECSMGDNLRSEFPEKEFVSTCQTCPHMKKITLEKVRDALLKEQFEIFLDEEVIRLAQKSVNRM
LELSYKK

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=341, Percent_Identity=30.2052785923754, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36789; Mature: 36658

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVSKDQLVQKLKPIYLPHEIEERILPLAEEIGRLKKEKNAVILGHNYMTPDVFWGVSD
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHCHHH
IIGDSLYLSKMAKETTANMILFNGVHFMAETAKILSPEKKVLIADPKAGCSLAESITRED
HHCCHHHHHHHHHHHHHCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
VKVLKAKYPGVPVVTYVNCSAEVKAETDVCCTSANAVQIVNAVEGDTVIFLPDEYLAGNV
HHHHHHCCCCCCEEEEEECCCEECCCCCCEECCCCCEEEEEECCCCEEEEECCHHHCCCC
RNQTSKTIISHPGRCMVHEIYTPEDIRSTKRLFPGGVTVITHPECHEDVVKEADFSGSTS
CCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCHH
QMVDFIRNSKTDKIMLVTECSMGDNLRSEFPEKEFVSTCQTCPHMKKITLEKVRDALLKE
HHHHHHHCCCCCEEEEEEECCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QFEIFLDEEVIRLAQKSVNRMLELSYKK
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLVSKDQLVQKLKPIYLPHEIEERILPLAEEIGRLKKEKNAVILGHNYMTPDVFWGVSD
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHCHHH
IIGDSLYLSKMAKETTANMILFNGVHFMAETAKILSPEKKVLIADPKAGCSLAESITRED
HHCCHHHHHHHHHHHHHCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
VKVLKAKYPGVPVVTYVNCSAEVKAETDVCCTSANAVQIVNAVEGDTVIFLPDEYLAGNV
HHHHHHCCCCCCEEEEEECCCEECCCCCCEECCCCCEEEEEECCCCEEEEECCHHHCCCC
RNQTSKTIISHPGRCMVHEIYTPEDIRSTKRLFPGGVTVITHPECHEDVVKEADFSGSTS
CCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCHH
QMVDFIRNSKTDKIMLVTECSMGDNLRSEFPEKEFVSTCQTCPHMKKITLEKVRDALLKE
HHHHHHHCCCCCEEEEEEECCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QFEIFLDEEVIRLAQKSVNRMLELSYKK
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA