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The map label for this gene is nudG [H]

Identifier: 182680553

GI number: 182680553

Start: 4147455

End: 4147862

Strand: Reverse

Name: nudG [H]

Synonym: Bind_3658

Alternate gene names: 182680553

Gene position: 4147862-4147455 (Counterclockwise)

Preceding gene: 182680554

Following gene: 182680551

Centisome position: 99.47

GC content: 64.22

Gene sequence:

>408_bases
GTGAGTCAGTCTCTGCTTCTCGTTGTCGCCGTGGCGCTGGTCGATCAGGATATGCGCGTGCTGATCGCCCAGCGCCCTCC
CGGCAAAACCCTCGCCGGCCTTTGGGAATTTCCCGGCGGCAAGGTCGAGCCGGGAGAAAGCCCCGAGGCGGCCCTAATCC
GTGAGCTCACCGAGGAATTGGGTATTACGGTCGCCGAACCTTGCCTCGCGCCCCTGACCTTCGCCAGCCACGCCTATGAG
CATTTTCATCTCCTGATGCCGCTCTATATCTGCCGGCGCTGGCAAGGCTTCGTCAGCCCGCGCGAGGGGCAGACTCTGAA
ATGGGTCGCGCCGCGTGCACTGCGCGACTATCCCATGCCGCCCGCCGACGAGCCTCTCATTTCCGCCCTGCTCGATCTTC
TGGCGTGA

Upstream 100 bases:

>100_bases
TCGATATTCGCGTCGATCTCGGGCTCGGCGAGGGAAGCGCCCGGCTCTGGACCTGCGACCTCACCAAAGCCTATGTCGAA
ATCAATGGTGATTACCGCTC

Downstream 100 bases:

>100_bases
ACCCGATGGAGGCTCAAGCCTCCATCGAAATGATCACCTTCAAGGCTTGTGTACTGGCCGCCTGACCGAAGGTTTCATAG
GCATCAAGGATCTGATCCAG

Product: mutator MutT protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MSQSLLLVVAVALVDQDMRVLIAQRPPGKTLAGLWEFPGGKVEPGESPEAALIRELTEELGITVAEPCLAPLTFASHAYE
HFHLLMPLYICRRWQGFVSPREGQTLKWVAPRALRDYPMPPADEPLISALLDLLA

Sequences:

>Translated_135_residues
MSQSLLLVVAVALVDQDMRVLIAQRPPGKTLAGLWEFPGGKVEPGESPEAALIRELTEELGITVAEPCLAPLTFASHAYE
HFHLLMPLYICRRWQGFVSPREGQTLKWVAPRALRDYPMPPADEPLISALLDLLA
>Mature_134_residues
SQSLLLVVAVALVDQDMRVLIAQRPPGKTLAGLWEFPGGKVEPGESPEAALIRELTEELGITVAEPCLAPLTFASHAYEH
FHLLMPLYICRRWQGFVSPREGQTLKWVAPRALRDYPMPPADEPLISALLDLLA

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=134, Percent_Identity=41.7910447761194, Blast_Score=91, Evalue=2e-20,
Organism=Escherichia coli, GI1786288, Length=130, Percent_Identity=36.1538461538462, Blast_Score=79, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14926; Mature: 14794

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSLLLVVAVALVDQDMRVLIAQRPPGKTLAGLWEFPGGKVEPGESPEAALIRELTEEL
CCCHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
GITVAEPCLAPLTFASHAYEHFHLLMPLYICRRWQGFVSPREGQTLKWVAPRALRDYPMP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHCCCCC
PADEPLISALLDLLA
CCCCHHHHHHHHHHC
>Mature Secondary Structure 
SQSLLLVVAVALVDQDMRVLIAQRPPGKTLAGLWEFPGGKVEPGESPEAALIRELTEEL
CCHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
GITVAEPCLAPLTFASHAYEHFHLLMPLYICRRWQGFVSPREGQTLKWVAPRALRDYPMP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHCCCCC
PADEPLISALLDLLA
CCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]