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The map label for this gene is argJ [H]

Identifier: 182680554

GI number: 182680554

Start: 4147859

End: 4149100

Strand: Reverse

Name: argJ [H]

Synonym: Bind_3659

Alternate gene names: 182680554

Gene position: 4149100-4147859 (Counterclockwise)

Preceding gene: 182680557

Following gene: 182680553

Centisome position: 99.5

GC content: 62.48

Gene sequence:

>1242_bases
ATGGCCGTTGCCGTTTCGCCGCTTGCCCCCAAAACCTATCCCGATCTTCCTCCCGTGGACGGCGTGCGTTTCGCGACCGG
CGCTGCAGGCATCCGCTATCAGGGCCGTACCGATGTCCTCCTCGCCCTGTTCGACAAGGGGACAGAAGTCGCCGGCGTCT
TCACCCGCTCGAAATGCCCCTCCGCACCGGTCGATTGGTGCAAGACCAAGCTCGAGGGAGGCAAGGCACGCGCGCTCGTC
GTCAATTCGGGCAATGCCAATGCCTTCACCGGCAAGCTCGGAGCCGAAGCGGTCAAGACGACCGCCTCGCTCGCAGCCAA
GGCGTTGGACGTGCCGCAATCGGAAATTTTCCTCGCCTCGACCGGCGTCATTGGAGAACCGCTCGACGCCAGCAAATTCG
AGGGTGTTCTGGAACCCTTGCGCGATGCCGCCTCCCCCGATGGTGCCCTTGATGCCGCCCGCGCGATCATGACCACGGAT
ACTTATCCAAAGGTCGCGGTGGCGCGAACCGAGATCGACGGGGTTCCGATTGTCATCACGGGCATTGCCAAGGGGGCTGG
CATGATCGCGCCGGATATGGCGACCATGCTGTCCTTCATCTTCACCGATGCGCCGATCGACGCGCCAGTGCTGCAATCCC
TGCTGACACGCGGCGTACAAGGGTCCTTCAATTCCATCACCGTCGACAGCGATACATCCACTTCCGATACTTTGCTGTTG
TTCGCCACCGGTGCGGCCGCGCACCGGGGCGCCCCACGGATCAAGACCAAGGGTGATCGCAAGCTCAAACCCTTTCGCAA
GGCGCTCGACGCCCTGCTGCTCGATCTCGCTCATCAAGTCGTAAAGGATGGCGAGGGCGCGCGGAAATTCGTCGAGATCG
TCGTCGAAGGCGCGGCGAGCCCGGGTGCCGCCAGGAAAATTGCCCGGTCCATTGCCGATTCACCCCTCGTCAAGACGGCG
ATCGCCGGCGAGGATGCCAATTGGGGCCGGATCGTCATGGCGGTCGGCAAGGCCGGGGAAAAGGCCGAGCGTGACAAACT
CGCCATCTGGTTCGGAGATATCCGCGTCGCTTACAAAGGCATGCGCGATCCAGCCTATGACGAGGCAGCCGTCTCACGCT
TGATGCAGGCCGACAAGATCGATATTCGCGTCGATCTCGGGCTCGGCGAGGGAAGCGCCCGGCTCTGGACCTGCGACCTC
ACCAAAGCCTATGTCGAAATCAATGGTGATTACCGCTCGTGA

Upstream 100 bases:

>100_bases
CCGGCCAGCGCCTGATGCACGAATCCAATCCAGCGCATCCCATCGTGCGTTTACGCATCCAAGGTCCGCACATCAAAGGT
TTGCTCAAGGAGGAGGCCCC

Downstream 100 bases:

>100_bases
GTCAGTCTCTGCTTCTCGTTGTCGCCGTGGCGCTGGTCGATCAGGATATGCGCGTGCTGATCGCCCAGCGCCCTCCCGGC
AAAACCCTCGCCGGCCTTTG

Product: arginine biosynthesis bifunctional protein ArgJ

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MAVAVSPLAPKTYPDLPPVDGVRFATGAAGIRYQGRTDVLLALFDKGTEVAGVFTRSKCPSAPVDWCKTKLEGGKARALV
VNSGNANAFTGKLGAEAVKTTASLAAKALDVPQSEIFLASTGVIGEPLDASKFEGVLEPLRDAASPDGALDAARAIMTTD
TYPKVAVARTEIDGVPIVITGIAKGAGMIAPDMATMLSFIFTDAPIDAPVLQSLLTRGVQGSFNSITVDSDTSTSDTLLL
FATGAAAHRGAPRIKTKGDRKLKPFRKALDALLLDLAHQVVKDGEGARKFVEIVVEGAASPGAARKIARSIADSPLVKTA
IAGEDANWGRIVMAVGKAGEKAERDKLAIWFGDIRVAYKGMRDPAYDEAAVSRLMQADKIDIRVDLGLGEGSARLWTCDL
TKAYVEINGDYRS

Sequences:

>Translated_413_residues
MAVAVSPLAPKTYPDLPPVDGVRFATGAAGIRYQGRTDVLLALFDKGTEVAGVFTRSKCPSAPVDWCKTKLEGGKARALV
VNSGNANAFTGKLGAEAVKTTASLAAKALDVPQSEIFLASTGVIGEPLDASKFEGVLEPLRDAASPDGALDAARAIMTTD
TYPKVAVARTEIDGVPIVITGIAKGAGMIAPDMATMLSFIFTDAPIDAPVLQSLLTRGVQGSFNSITVDSDTSTSDTLLL
FATGAAAHRGAPRIKTKGDRKLKPFRKALDALLLDLAHQVVKDGEGARKFVEIVVEGAASPGAARKIARSIADSPLVKTA
IAGEDANWGRIVMAVGKAGEKAERDKLAIWFGDIRVAYKGMRDPAYDEAAVSRLMQADKIDIRVDLGLGEGSARLWTCDL
TKAYVEINGDYRS
>Mature_412_residues
AVAVSPLAPKTYPDLPPVDGVRFATGAAGIRYQGRTDVLLALFDKGTEVAGVFTRSKCPSAPVDWCKTKLEGGKARALVV
NSGNANAFTGKLGAEAVKTTASLAAKALDVPQSEIFLASTGVIGEPLDASKFEGVLEPLRDAASPDGALDAARAIMTTDT
YPKVAVARTEIDGVPIVITGIAKGAGMIAPDMATMLSFIFTDAPIDAPVLQSLLTRGVQGSFNSITVDSDTSTSDTLLLF
ATGAAAHRGAPRIKTKGDRKLKPFRKALDALLLDLAHQVVKDGEGARKFVEIVVEGAASPGAARKIARSIADSPLVKTAI
AGEDANWGRIVMAVGKAGEKAERDKLAIWFGDIRVAYKGMRDPAYDEAAVSRLMQADKIDIRVDLGLGEGSARLWTCDLT
KAYVEINGDYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=416, Percent_Identity=36.0576923076923, Blast_Score=240, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 43344; Mature: 43213

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAVSPLAPKTYPDLPPVDGVRFATGAAGIRYQGRTDVLLALFDKGTEVAGVFTRSKCP
CEEECCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCEEEEEECCCCCEEEEEECCCCC
SAPVDWCKTKLEGGKARALVVNSGNANAFTGKLGAEAVKTTASLAAKALDVPQSEIFLAS
CCCHHHHHHHCCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHEEEEE
TGVIGEPLDASKFEGVLEPLRDAASPDGALDAARAIMTTDTYPKVAVARTEIDGVPIVIT
CCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEE
GIAKGAGMIAPDMATMLSFIFTDAPIDAPVLQSLLTRGVQGSFNSITVDSDTSTSDTLLL
ECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEE
FATGAAAHRGAPRIKTKGDRKLKPFRKALDALLLDLAHQVVKDGEGARKFVEIVVEGAAS
EEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
PGAARKIARSIADSPLVKTAIAGEDANWGRIVMAVGKAGEKAERDKLAIWFGDIRVAYKG
CHHHHHHHHHHCCCCHHHHEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEECEEEEECC
MRDPAYDEAAVSRLMQADKIDIRVDLGLGEGSARLWTCDLTKAYVEINGDYRS
CCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEECEEEEEEECCCCCC
>Mature Secondary Structure 
AVAVSPLAPKTYPDLPPVDGVRFATGAAGIRYQGRTDVLLALFDKGTEVAGVFTRSKCP
EEECCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCEEEEEECCCCCEEEEEECCCCC
SAPVDWCKTKLEGGKARALVVNSGNANAFTGKLGAEAVKTTASLAAKALDVPQSEIFLAS
CCCHHHHHHHCCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHEEEEE
TGVIGEPLDASKFEGVLEPLRDAASPDGALDAARAIMTTDTYPKVAVARTEIDGVPIVIT
CCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEE
GIAKGAGMIAPDMATMLSFIFTDAPIDAPVLQSLLTRGVQGSFNSITVDSDTSTSDTLLL
ECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEE
FATGAAAHRGAPRIKTKGDRKLKPFRKALDALLLDLAHQVVKDGEGARKFVEIVVEGAAS
EEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
PGAARKIARSIADSPLVKTAIAGEDANWGRIVMAVGKAGEKAERDKLAIWFGDIRVAYKG
CHHHHHHHHHHCCCCHHHHEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEECEEEEECC
MRDPAYDEAAVSRLMQADKIDIRVDLGLGEGSARLWTCDLTKAYVEINGDYRS
CCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEECEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]