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The map label for this gene is recQ [H]

Identifier: 182680391

GI number: 182680391

Start: 3966649

End: 3968556

Strand: Reverse

Name: recQ [H]

Synonym: Bind_3491

Alternate gene names: 182680391

Gene position: 3968556-3966649 (Counterclockwise)

Preceding gene: 182680392

Following gene: 182680390

Centisome position: 95.17

GC content: 60.59

Gene sequence:

>1908_bases
TTGCAGACAAAGCCCGATCTCGATGAAGCCCGGCGCGTCTTGCAAGAGGTTTTTGGGTTTGCTGATTTTCGTCCGGGGCA
GGCTGAGATCCTGCAAGCCGTGCTCGATGGCGACGATATTCTCGCCATCATGCCGACGGGAGCTGGCAAATCGCTCTGCT
ACCAATTGCCGGCTCTGCTGCGGCCGGGTTTGACGGTCGTGGTTTCGCCGCTGATCGCTCTCATGCGCGATCAGGTCGAG
CAGTTGAAGCAGCGCGGCGTTCCGGCGGCGGCTTTGAATTCGACCAATAGCGGCCAGGACAATGCCATGATCGAGGCGGC
CCTGCTTAAGGGTCGTTATCGCCTTGTCTATGTCGCGCCGGAGCGTTTCGTCCGCGCCGATACTTTATCCATGCTGCGGC
GCGCAGGCGCCGATCTGCTCGCCATCGATGAGGCCCATTGCGTTTCGCAATGGGGGCATGATTTCCGGCCGGAATATCGT
GCCTTGGGCGAAAGCCTCGTGGCGCTCGGCCGGCCGCAGATTGTCGCCGTCACCGCGACCGCCGATGGGCCGACGCGCGC
TGAAATCATGGAGCGGCTGTTTCCCGCCGAACCCCGGCAGTTCATCCGCTCTTTCGACCGGCCCAATTTGCGGCTCGCCA
TGCAGCGCAAGCATAAGCCTGTGCAACAGATCCTGGCGATGATCGCCCGCCACAAGGGAGAGAGCGGCATTATCTATTGC
GCCTCGCGCAAGGGCGTCGAGAAACTGACCGAGATCTTGAGCGCGCAAGGCATATTTGCGCTGCCCTATCATGCGGGCCT
GGCGCCCGAAATCCGGGCGGCGCATCAGGATATGTTCGTGCGCCATGAGAATGTGGTCATTGTGGCGACCATCGCTTTCG
GCATGGGGATCGACAAGCCGGATGTGCGCTTTGTCTGCCATGCCGATCTGCCGGGCAGTATCGAGGCCTATTATCAGGAA
ATCGGCCGCGCCGGCCGCGATGGCCTGCCTGCCGACACGCTGACTTTGTTCGGTGAGGCCGATATCCGTCTGCGTGAGCG
CCAGATCGAGGACAACGACGCCGCGCCCGAACGCAAAAGGCTCGACCGGCGCAAATTACAGGAGCTGATCGCGCTTTGTG
AGACGCCGCGTTGCCGCCGCCAGACTTTGCTCGCGGCCTTTGGCGAACAGTCTGAACCTTGCGGCAATTGTGATATTTGT
GAGGGCCGCTGGCCCTTGTTCGATGGCGTTGTCGCGGCGCAAAAAGTCATGTCGGCGATTCTACGGACATCGGGCCGTTT
CTTTTCCGGTCATCTCGCCCATCTGCTGATTGGCCATGCGACCGAGGCGATCAAACGCCATAGCCACGATCTTTTGCCGA
CTTTCGGCGTCGGGCGCGAATTCACGCTCTCGGAATGGCGCAGCATTTTCCACCAATTGCATGCCCTGAACCTGATCGAA
CAGGATGAGGAGGATCGCGACCGCTGGTGTTTGACGCAAGGCGGGCGAGCGGTCTTGCGGGGGGAGGCGGAACTGACTTT
GCGCGGGGAAATGGCCTTGCCCACCGGGCGCAGCGCCGATATTCGCAAAAGCCTGCGCGAGATCGAAAGCGGCGCGGAGG
CAGATTATGCCGATCGTGATCTCGCCCAAAAAGCATTTACCCGAGAGCCGCCGCAAATTTCTTCGGCCGATCTGACGATT
CATGAAACGAGGCTGTTCGTCGCGCTGAAAGCGGAGCGCTTGTCTCTCGCTAAGGCGCAGAAACAGCCGCCTTATGTTAT
TTTTCATGATGCCGTATTGGTCGAAATCGCTCGGCGGGCGCCGCGCGATGAGGCCCAATTGCTGGAAATTCATGGTATTG
GTCCGGCCAAGGCAGCCCGTTACGGCGAGGCCATGCTTGCTGTCGTCGCCCGTCACGAACAAGCCTGA

Upstream 100 bases:

>100_bases
ACCGGGGTAAAGCGATTCGAATCGGAGCGTGGCCCTGGGTTTTTAGCGATCATCAGACCAACGCCGGCCCTCTCCGAACA
AAAAAACGGACGAGGCCCCC

Downstream 100 bases:

>100_bases
ATAGTGCAAACTCGAAGATCCAACCAAGGTCTCGCGTGTCCGAGTCTCCCTCCGGCTTTCCCCAATCGCCCTCCGGACCC
TCCACGGTTCCGGCCGCCGC

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MQTKPDLDEARRVLQEVFGFADFRPGQAEILQAVLDGDDILAIMPTGAGKSLCYQLPALLRPGLTVVVSPLIALMRDQVE
QLKQRGVPAAALNSTNSGQDNAMIEAALLKGRYRLVYVAPERFVRADTLSMLRRAGADLLAIDEAHCVSQWGHDFRPEYR
ALGESLVALGRPQIVAVTATADGPTRAEIMERLFPAEPRQFIRSFDRPNLRLAMQRKHKPVQQILAMIARHKGESGIIYC
ASRKGVEKLTEILSAQGIFALPYHAGLAPEIRAAHQDMFVRHENVVIVATIAFGMGIDKPDVRFVCHADLPGSIEAYYQE
IGRAGRDGLPADTLTLFGEADIRLRERQIEDNDAAPERKRLDRRKLQELIALCETPRCRRQTLLAAFGEQSEPCGNCDIC
EGRWPLFDGVVAAQKVMSAILRTSGRFFSGHLAHLLIGHATEAIKRHSHDLLPTFGVGREFTLSEWRSIFHQLHALNLIE
QDEEDRDRWCLTQGGRAVLRGEAELTLRGEMALPTGRSADIRKSLREIESGAEADYADRDLAQKAFTREPPQISSADLTI
HETRLFVALKAERLSLAKAQKQPPYVIFHDAVLVEIARRAPRDEAQLLEIHGIGPAKAARYGEAMLAVVARHEQA

Sequences:

>Translated_635_residues
MQTKPDLDEARRVLQEVFGFADFRPGQAEILQAVLDGDDILAIMPTGAGKSLCYQLPALLRPGLTVVVSPLIALMRDQVE
QLKQRGVPAAALNSTNSGQDNAMIEAALLKGRYRLVYVAPERFVRADTLSMLRRAGADLLAIDEAHCVSQWGHDFRPEYR
ALGESLVALGRPQIVAVTATADGPTRAEIMERLFPAEPRQFIRSFDRPNLRLAMQRKHKPVQQILAMIARHKGESGIIYC
ASRKGVEKLTEILSAQGIFALPYHAGLAPEIRAAHQDMFVRHENVVIVATIAFGMGIDKPDVRFVCHADLPGSIEAYYQE
IGRAGRDGLPADTLTLFGEADIRLRERQIEDNDAAPERKRLDRRKLQELIALCETPRCRRQTLLAAFGEQSEPCGNCDIC
EGRWPLFDGVVAAQKVMSAILRTSGRFFSGHLAHLLIGHATEAIKRHSHDLLPTFGVGREFTLSEWRSIFHQLHALNLIE
QDEEDRDRWCLTQGGRAVLRGEAELTLRGEMALPTGRSADIRKSLREIESGAEADYADRDLAQKAFTREPPQISSADLTI
HETRLFVALKAERLSLAKAQKQPPYVIFHDAVLVEIARRAPRDEAQLLEIHGIGPAKAARYGEAMLAVVARHEQA
>Mature_635_residues
MQTKPDLDEARRVLQEVFGFADFRPGQAEILQAVLDGDDILAIMPTGAGKSLCYQLPALLRPGLTVVVSPLIALMRDQVE
QLKQRGVPAAALNSTNSGQDNAMIEAALLKGRYRLVYVAPERFVRADTLSMLRRAGADLLAIDEAHCVSQWGHDFRPEYR
ALGESLVALGRPQIVAVTATADGPTRAEIMERLFPAEPRQFIRSFDRPNLRLAMQRKHKPVQQILAMIARHKGESGIIYC
ASRKGVEKLTEILSAQGIFALPYHAGLAPEIRAAHQDMFVRHENVVIVATIAFGMGIDKPDVRFVCHADLPGSIEAYYQE
IGRAGRDGLPADTLTLFGEADIRLRERQIEDNDAAPERKRLDRRKLQELIALCETPRCRRQTLLAAFGEQSEPCGNCDIC
EGRWPLFDGVVAAQKVMSAILRTSGRFFSGHLAHLLIGHATEAIKRHSHDLLPTFGVGREFTLSEWRSIFHQLHALNLIE
QDEEDRDRWCLTQGGRAVLRGEAELTLRGEMALPTGRSADIRKSLREIESGAEADYADRDLAQKAFTREPPQISSADLTI
HETRLFVALKAERLSLAKAQKQPPYVIFHDAVLVEIARRAPRDEAQLLEIHGIGPAKAARYGEAMLAVVARHEQA

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI14591902, Length=413, Percent_Identity=39.4673123486683, Blast_Score=295, Evalue=8e-80,
Organism=Homo sapiens, GI14591904, Length=413, Percent_Identity=39.4673123486683, Blast_Score=295, Evalue=8e-80,
Organism=Homo sapiens, GI4557365, Length=674, Percent_Identity=30.7121661721068, Blast_Score=289, Evalue=5e-78,
Organism=Homo sapiens, GI110735439, Length=693, Percent_Identity=32.034632034632, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI169218196, Length=693, Percent_Identity=32.034632034632, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI148612816, Length=427, Percent_Identity=37.7049180327869, Blast_Score=242, Evalue=7e-64,
Organism=Homo sapiens, GI51242947, Length=358, Percent_Identity=41.340782122905, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI51242943, Length=348, Percent_Identity=42.2413793103448, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI284005309, Length=391, Percent_Identity=37.0843989769821, Blast_Score=185, Evalue=9e-47,
Organism=Homo sapiens, GI7661920, Length=353, Percent_Identity=21.8130311614731, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI48994977, Length=624, Percent_Identity=42.4679487179487, Blast_Score=488, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI25145561, Length=660, Percent_Identity=33.030303030303, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71987997, Length=447, Percent_Identity=37.1364653243848, Blast_Score=278, Evalue=9e-75,
Organism=Caenorhabditis elegans, GI71987993, Length=447, Percent_Identity=37.1364653243848, Blast_Score=277, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI32564293, Length=689, Percent_Identity=31.7851959361393, Blast_Score=271, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17552866, Length=443, Percent_Identity=36.3431151241535, Blast_Score=237, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17537549, Length=354, Percent_Identity=23.1638418079096, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17510307, Length=380, Percent_Identity=21.8421052631579, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17510309, Length=380, Percent_Identity=21.8421052631579, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555296, Length=355, Percent_Identity=22.5352112676056, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71995514, Length=380, Percent_Identity=21.8421052631579, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323844, Length=544, Percent_Identity=35.1102941176471, Blast_Score=308, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6324217, Length=379, Percent_Identity=23.2189973614776, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323021, Length=405, Percent_Identity=22.4691358024691, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646066, Length=647, Percent_Identity=32.6120556414219, Blast_Score=288, Evalue=9e-78,
Organism=Drosophila melanogaster, GI24664226, Length=423, Percent_Identity=35.6973995271868, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI62472181, Length=423, Percent_Identity=35.6973995271868, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24664230, Length=423, Percent_Identity=35.6973995271868, Blast_Score=246, Evalue=4e-65,
Organism=Drosophila melanogaster, GI21358123, Length=352, Percent_Identity=36.9318181818182, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI28574962, Length=360, Percent_Identity=26.1111111111111, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585582, Length=338, Percent_Identity=22.7810650887574, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 70573; Mature: 70573

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTKPDLDEARRVLQEVFGFADFRPGQAEILQAVLDGDDILAIMPTGAGKSLCYQLPALL
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
RPGLTVVVSPLIALMRDQVEQLKQRGVPAAALNSTNSGQDNAMIEAALLKGRYRLVYVAP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCEEEEEECC
ERFVRADTLSMLRRAGADLLAIDEAHCVSQWGHDFRPEYRALGESLVALGRPQIVAVTAT
HHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEC
ADGPTRAEIMERLFPAEPRQFIRSFDRPNLRLAMQRKHKPVQQILAMIARHKGESGIIYC
CCCCHHHHHHHHHCCCCHHHHHHHCCCCCEEHHHHHCCCHHHHHHHHHHHCCCCCCEEEE
ASRKGVEKLTEILSAQGIFALPYHAGLAPEIRAAHQDMFVRHENVVIVATIAFGMGIDKP
ECCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHEEECCEEEEEEEEHHCCCCCC
DVRFVCHADLPGSIEAYYQEIGRAGRDGLPADTLTLFGEADIRLRERQIEDNDAAPERKR
CCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCCCHHHH
LDRRKLQELIALCETPRCRRQTLLAAFGEQSEPCGNCDICEGRWPLFDGVVAAQKVMSAI
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LRTSGRFFSGHLAHLLIGHATEAIKRHSHDLLPTFGVGREFTLSEWRSIFHQLHALNLIE
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QDEEDRDRWCLTQGGRAVLRGEAELTLRGEMALPTGRSADIRKSLREIESGAEADYADRD
CCCCHHHCEECCCCCCEEEECCCEEEEECCEECCCCCCHHHHHHHHHHHCCCCCCCHHHH
LAQKAFTREPPQISSADLTIHETRLFVALKAERLSLAKAQKQPPYVIFHDAVLVEIARRA
HHHHHHCCCCCCCCCCCEEEEEEEEEEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHC
PRDEAQLLEIHGIGPAKAARYGEAMLAVVARHEQA
CCCCHHEEEEECCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTKPDLDEARRVLQEVFGFADFRPGQAEILQAVLDGDDILAIMPTGAGKSLCYQLPALL
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
RPGLTVVVSPLIALMRDQVEQLKQRGVPAAALNSTNSGQDNAMIEAALLKGRYRLVYVAP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCEEEEEECC
ERFVRADTLSMLRRAGADLLAIDEAHCVSQWGHDFRPEYRALGESLVALGRPQIVAVTAT
HHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEC
ADGPTRAEIMERLFPAEPRQFIRSFDRPNLRLAMQRKHKPVQQILAMIARHKGESGIIYC
CCCCHHHHHHHHHCCCCHHHHHHHCCCCCEEHHHHHCCCHHHHHHHHHHHCCCCCCEEEE
ASRKGVEKLTEILSAQGIFALPYHAGLAPEIRAAHQDMFVRHENVVIVATIAFGMGIDKP
ECCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHEEECCEEEEEEEEHHCCCCCC
DVRFVCHADLPGSIEAYYQEIGRAGRDGLPADTLTLFGEADIRLRERQIEDNDAAPERKR
CCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCCCHHHH
LDRRKLQELIALCETPRCRRQTLLAAFGEQSEPCGNCDICEGRWPLFDGVVAAQKVMSAI
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LRTSGRFFSGHLAHLLIGHATEAIKRHSHDLLPTFGVGREFTLSEWRSIFHQLHALNLIE
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QDEEDRDRWCLTQGGRAVLRGEAELTLRGEMALPTGRSADIRKSLREIESGAEADYADRD
CCCCHHHCEECCCCCCEEEECCCEEEEECCEECCCCCCHHHHHHHHHHHCCCCCCCHHHH
LAQKAFTREPPQISSADLTIHETRLFVALKAERLSLAKAQKQPPYVIFHDAVLVEIARRA
HHHHHHCCCCCCCCCCCEEEEEEEEEEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHC
PRDEAQLLEIHGIGPAKAARYGEAMLAVVARHEQA
CCCCHHEEEEECCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]