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The map label for this gene is yusP [H]

Identifier: 182680390

GI number: 182680390

Start: 3965102

End: 3966613

Strand: Reverse

Name: yusP [H]

Synonym: Bind_3490

Alternate gene names: 182680390

Gene position: 3966613-3965102 (Counterclockwise)

Preceding gene: 182680391

Following gene: 182680389

Centisome position: 95.12

GC content: 61.64

Gene sequence:

>1512_bases
GTGTCCGAGTCTCCCTCCGGCTTTCCCCAATCGCCCTCCGGACCCTCCACGGTTCCGGCCGCCGCGTCAGCGCCGCTGAC
GCGCTCGGAAATTCTCTGGATTTTCTCAGGCCTCATGCTCGCCATGTTGCTGAGCTCGATGGACCAGACCATTGTCGCGA
CGGCCATGCCGACGATCGGCCGTGATCTTGGCGATGTCGAACATCTGCCTTGGGTCGTGACCGCTTATCTTCTGGCGGCG
ACCGCCGCCACGCCGCTTGGCGGTAAGCTGGCCGATATTTACGGCCGCCGCATTATCCTGCTCACCTCGCTCGGCCTGTT
TCTCTTGGGGTCCATCGCCTGTGGCCTTGCGCGGTCCATGACCCTTTTGATCCTGGCGCGCGGCCTCCAGGGTCTGGGGG
GCGGCGGTCTGATCTCGCTGGCGCAAACCATCATTGCCGACCTCGTCACCCCGCGCGAGCGCGCGACCTATCAGATCCAT
ATCGCCTCGGTTTTCATGGCTTCGAGCCTTGGCGGCCCGGTGCTTGGCGGTTTTCTGGCGCAGCATGGCCATTGGTCGCT
GATTTTCTGGATCAATATCCCCTTCAGCCTCGCCGCTTTGTTCATGTGCGGCAAATATTTGCGCAAGCTGCCGCGGCGCG
AGCATCCTCACAAGCTCGATCTCGTCGGCGCCGTCTTGCTCCTCACCGCGACGACGAGTCTTTTGCTCGCCTTGAGTACC
GGCGCGGCGCAGGGGTGGACGTCGCCCTTTGTGGCGATGCTTATCGTGCTGAGCCTTGTGAGTTGGACAAGCCTCATCTT
TTGGCTGCACAGGACCGCCGAGCCCCTGATCCCGATTGCCCTGCTGCATGATAATGTCGTTGCCCGCGCCACGCTCGGGG
CCTCGCTTAGCATCGGCGTCTTCATCTCCCTGTCGATCTATATGCCGCTCTATTTCGAGGCCTATCGCCATTTGAGCGCG
AGCCAGTCGGGCCTTGCTCTTCTGCCGCTCATGGCCGGCACGGTCATTGGCTCGACCCTATCTGGCCGGCTCATGATCAG
GGTGATCCATTATAAGCGCGTGCCGCTCGCGGGGCTTGCTATTGCCTTTAGCGCCACCTGTCTGCTCGCTGCCGAGTCGA
TGACCCTGCCCTTGCCCTGGCTCTCCATCATTCTGGGTCTGGTCAGCATGGGGCTCGGCCTCGTTTTGACCATTTCGACG
GTTTCGGTCCAGAATGCGACGCCCCCGCATCAGCTCGGCACCGCGACGGCAGTGATGAATCTCTGTCGTCAGCTCGTCGC
TGCAATCATCGTCGCGATTTTCGGCGCCATGATTCTTGGCTCGGGGCGAGGCGTGGAGAGTGTTTCGGCCGAGGGTTTGA
GCCCTGACGAACAAAGGCTGCTTGGTTCCTCTTACACCTACGTCTTCATTGCCGCCGCTGGTCTTATGGCGATCGCTTTT
TGCGCCTATTTGCGCATGGAGGAGCGGCCGCTGACCGGATCGCGGTCATCCGACCACCCTGCTTCTTCCTAA

Upstream 100 bases:

>100_bases
CGGCCAAGGCAGCCCGTTACGGCGAGGCCATGCTTGCTGTCGTCGCCCGTCACGAACAAGCCTGAATAGTGCAAACTCGA
AGATCCAACCAAGGTCTCGC

Downstream 100 bases:

>100_bases
AGCCCGCCGCTGATGGGGCTTCTCATGCCATCGCTCATATTGTAGAGCCTGATCCGCGCAAAAGGGAGCAAGATGCATGA
CGCAAGCGGAGACGGCGATT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MSESPSGFPQSPSGPSTVPAAASAPLTRSEILWIFSGLMLAMLLSSMDQTIVATAMPTIGRDLGDVEHLPWVVTAYLLAA
TAATPLGGKLADIYGRRIILLTSLGLFLLGSIACGLARSMTLLILARGLQGLGGGGLISLAQTIIADLVTPRERATYQIH
IASVFMASSLGGPVLGGFLAQHGHWSLIFWINIPFSLAALFMCGKYLRKLPRREHPHKLDLVGAVLLLTATTSLLLALST
GAAQGWTSPFVAMLIVLSLVSWTSLIFWLHRTAEPLIPIALLHDNVVARATLGASLSIGVFISLSIYMPLYFEAYRHLSA
SQSGLALLPLMAGTVIGSTLSGRLMIRVIHYKRVPLAGLAIAFSATCLLAAESMTLPLPWLSIILGLVSMGLGLVLTIST
VSVQNATPPHQLGTATAVMNLCRQLVAAIIVAIFGAMILGSGRGVESVSAEGLSPDEQRLLGSSYTYVFIAAAGLMAIAF
CAYLRMEERPLTGSRSSDHPASS

Sequences:

>Translated_503_residues
MSESPSGFPQSPSGPSTVPAAASAPLTRSEILWIFSGLMLAMLLSSMDQTIVATAMPTIGRDLGDVEHLPWVVTAYLLAA
TAATPLGGKLADIYGRRIILLTSLGLFLLGSIACGLARSMTLLILARGLQGLGGGGLISLAQTIIADLVTPRERATYQIH
IASVFMASSLGGPVLGGFLAQHGHWSLIFWINIPFSLAALFMCGKYLRKLPRREHPHKLDLVGAVLLLTATTSLLLALST
GAAQGWTSPFVAMLIVLSLVSWTSLIFWLHRTAEPLIPIALLHDNVVARATLGASLSIGVFISLSIYMPLYFEAYRHLSA
SQSGLALLPLMAGTVIGSTLSGRLMIRVIHYKRVPLAGLAIAFSATCLLAAESMTLPLPWLSIILGLVSMGLGLVLTIST
VSVQNATPPHQLGTATAVMNLCRQLVAAIIVAIFGAMILGSGRGVESVSAEGLSPDEQRLLGSSYTYVFIAAAGLMAIAF
CAYLRMEERPLTGSRSSDHPASS
>Mature_502_residues
SESPSGFPQSPSGPSTVPAAASAPLTRSEILWIFSGLMLAMLLSSMDQTIVATAMPTIGRDLGDVEHLPWVVTAYLLAAT
AATPLGGKLADIYGRRIILLTSLGLFLLGSIACGLARSMTLLILARGLQGLGGGGLISLAQTIIADLVTPRERATYQIHI
ASVFMASSLGGPVLGGFLAQHGHWSLIFWINIPFSLAALFMCGKYLRKLPRREHPHKLDLVGAVLLLTATTSLLLALSTG
AAQGWTSPFVAMLIVLSLVSWTSLIFWLHRTAEPLIPIALLHDNVVARATLGASLSIGVFISLSIYMPLYFEAYRHLSAS
QSGLALLPLMAGTVIGSTLSGRLMIRVIHYKRVPLAGLAIAFSATCLLAAESMTLPLPWLSIILGLVSMGLGLVLTISTV
SVQNATPPHQLGTATAVMNLCRQLVAAIIVAIFGAMILGSGRGVESVSAEGLSPDEQRLLGSSYTYVFIAAAGLMAIAFC
AYLRMEERPLTGSRSSDHPASS

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=412, Percent_Identity=27.4271844660194, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788710, Length=423, Percent_Identity=26.241134751773, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081983, Length=409, Percent_Identity=28.6063569682152, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790195, Length=458, Percent_Identity=25.764192139738, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788392, Length=431, Percent_Identity=27.3781902552204, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790146, Length=166, Percent_Identity=30.7228915662651, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323735, Length=320, Percent_Identity=28.75, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319770, Length=413, Percent_Identity=27.1186440677966, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325455, Length=233, Percent_Identity=29.1845493562232, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322958, Length=165, Percent_Identity=30.3030303030303, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6321663, Length=229, Percent_Identity=24.4541484716157, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53021; Mature: 52889

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESPSGFPQSPSGPSTVPAAASAPLTRSEILWIFSGLMLAMLLSSMDQTIVATAMPTIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDLGDVEHLPWVVTAYLLAATAATPLGGKLADIYGRRIILLTSLGLFLLGSIACGLARSM
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TLLILARGLQGLGGGGLISLAQTIIADLVTPRERATYQIHIASVFMASSLGGPVLGGFLA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHH
QHGHWSLIFWINIPFSLAALFMCGKYLRKLPRREHPHKLDLVGAVLLLTATTSLLLALST
CCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GAAQGWTSPFVAMLIVLSLVSWTSLIFWLHRTAEPLIPIALLHDNVVARATLGASLSIGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHCCCCEEHHH
FISLSIYMPLYFEAYRHLSASQSGLALLPLMAGTVIGSTLSGRLMIRVIHYKRVPLAGLA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHCCCCHHHHH
IAFSATCLLAAESMTLPLPWLSIILGLVSMGLGLVLTISTVSVQNATPPHQLGTATAVMN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHEEEEEEEEECCCCCCHHHHHHHHHHH
LCRQLVAAIIVAIFGAMILGSGRGVESVSAEGLSPDEQRLLGSSYTYVFIAAAGLMAIAF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
CAYLRMEERPLTGSRSSDHPASS
HHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SESPSGFPQSPSGPSTVPAAASAPLTRSEILWIFSGLMLAMLLSSMDQTIVATAMPTIG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDLGDVEHLPWVVTAYLLAATAATPLGGKLADIYGRRIILLTSLGLFLLGSIACGLARSM
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TLLILARGLQGLGGGGLISLAQTIIADLVTPRERATYQIHIASVFMASSLGGPVLGGFLA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHH
QHGHWSLIFWINIPFSLAALFMCGKYLRKLPRREHPHKLDLVGAVLLLTATTSLLLALST
CCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GAAQGWTSPFVAMLIVLSLVSWTSLIFWLHRTAEPLIPIALLHDNVVARATLGASLSIGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHCCCCEEHHH
FISLSIYMPLYFEAYRHLSASQSGLALLPLMAGTVIGSTLSGRLMIRVIHYKRVPLAGLA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHCCCCHHHHH
IAFSATCLLAAESMTLPLPWLSIILGLVSMGLGLVLTISTVSVQNATPPHQLGTATAVMN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHEEEEEEEEECCCCCCHHHHHHHHHHH
LCRQLVAAIIVAIFGAMILGSGRGVESVSAEGLSPDEQRLLGSSYTYVFIAAAGLMAIAF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
CAYLRMEERPLTGSRSSDHPASS
HHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]