Click here to switch to the map view.

The map label for this gene is stc [H]

Identifier: 182680292

GI number: 182680292

Start: 3850468

End: 3852537

Strand: Reverse

Name: stc [H]

Synonym: Bind_3392

Alternate gene names: 182680292

Gene position: 3852537-3850468 (Counterclockwise)

Preceding gene: 182680293

Following gene: 182680291

Centisome position: 92.38

GC content: 60.24

Gene sequence:

>2070_bases
GTGGTCATTCTCGGCAAGAGTAACAAGCAGACTGGGCCGGAACAATGGGCCGGTGAGATCAGCCCCGCCTCAGAACATCT
CATCATGCGTGCCTGGGAGGATTATCTGACTGCCGAGGCCGAAGAACCGCAGGTACGCGACATTGTCGCCAATTCCTGGA
AGCGCTGTTCCGCGATCGGCATCGATCCTCAGCGGCCGGGTTCTTGCGCCATCCTCGAGACTGTGGAGTTCGAGCGACGT
CTGCGCGGCAGCAAAGTCCTTTTGAATGCCGCCTCGGACATTCTCGAAGAAGCCAACACGCTTTTCGAGGGGACCGGCTC
CATGTTGCTTTTGACGGATGTCGATGGCGTCATTCTGCGGGCTATCGGTGATACCAAGACGATCGACGCCGGGCACGATA
TCAATCTCGTTGTCGGTGCCGACTGGAGTGAAAACAAGGCCGGCACGAATGGCATCGGCACGACGCTCGCCTCGCATCGT
CCCGTCCTCATCTATGGACCGGAACATTTCTGTTCGCTCACCAAGAACTGGACCTGCGTCGGTTCGCCGGTGCGGCATCC
GCTGAGCGGCGAAATTTTGGGCCTGGTCGATATGTCGGGTCGCAAATGTACCTTTCAGCAGCAGCATCTTGCTTTTGCGG
TGATGGTGGCCCGGCGGATCGAGACGGTGCTGACGGTCCATTTCGAGATCGAGCGCCGCAAGTTGCTCGAATATAGCGCG
CAGATGACACGCGGCTCCTGGAGCGATGGTGTCGTCATTGTCGATCGTTTCGGCAAAGTACTTTCTACTGATGAACAGGC
CCCACGTCTTCTCGCCTTGCGCGCCACGCATGGAGAACGGCTGAGTGCGTCCCTCAATGCCGAAAGGCCTCTGTTGCGAC
CGAAAGGCGATGGTAGGAGTTTCGATCTTTCCGTCAGTGCCGAATATGGCATCGACGCCGATAATGTCATGCCGGTTCAT
CACCAGGGCGAATTGATCGGCGCCGTGATCATCGCGCCGAGGACGGCGCCTGCCGTTGCCACGGCGCTCAAGCAAAGCCG
GGCTTTCGATCCGATCGTGACTGGTTGCGCCACAGTGCTTGACACGATCCAGCGCGCCCGCCGGCTGGCGGCCTATCAGG
CCCCGGTGCTCATCGAGGGTGAGACCGGCGTTGGCAAGGAATTGTTCGCCCGTGCCATTCATGATGCGAGCCCCTGCGCG
AGCGGTCCCTTTGTGGCCTTTAATTGCGGTGCGGTCTCGCGTGATCTGATCGCCACGGAATTGTTCGGCTATGTCAAGGG
CGCCTTCACGGGCGCCGCCACAACCGGGAACATCGGCCGTTTTGAACGGGCCAACCATGGCACGCTCTGCCTCGACGAAA
TCGGTGAATTGCCGCTCGACCTGCAACCCTTCCTGCTGCGGGTCCTGGAGGAAGGGACGGTCTATCGCGTGGGTGATGCG
ACGCCGCATCCGGTCAAGGTCCGCCTTATCGCCATGACCAATCGTGATCTCCGCGAGGAGGTGGAAAAGGGCCGCTTCCG
CCGCGATTTGCTCTATCGGTTGAATGTCTCGACCCTGCGCGTACCACCCCTGCGCAAGCGGCAGGGTGATGCGGTGCTGC
TCGCCCAGCATTTCCTTGATCAATTGAGCAAGAAACATGGGTTCGGCTTACGCCGTTTCGCGCCCGATGTGCTTGACCTG
TTCAAGACCTATGGATGGCCGGGCAATATCCGTGAACTCCGCAATGCTGTGGAAAGCGCGCTTCTGCTCTGTGATACGCC
GGTCATCGGCCGCGGCTGGCTGCCCGATGCGATTTTGGAGGACCATGCGGCCCAGGCTGCCCCTGCGCAGCCAGTGGCGA
CACAGCCCATTTTCATGCCGCCGGGACCCATGGCCTATGAGGCTACGGGCTATCCGCCGGGCATCGCCACGCCGCGCGGC
AGTGATCTTCGCGCCATGGACAAGGCGCATATTTTGAGTGTGCTCGAACGCTATCAGTGGAACATCAGTTTGAGCGCGGG
TGCGCTCGGCATTGCGCGCAGCACGCTTTACCGCCGCATGCAGGCCTATGGAATAGACATGCATCGTTAA

Upstream 100 bases:

>100_bases
TGTGGACGCTGCCTAGAATAGGGATAGTCCGCGTAAAGATCGGAAATCCTTAATAAAAACAAGGCGCATGAGGAAACAAT
TGTCGCAAGGAGCGTCCAAC

Downstream 100 bases:

>100_bases
GGCTTGAGGCGGGAAAGCATCAAGCCCTGCTATGTATGCGTATTCAGGACCGCCTGATGCATTGTCAAACGAAGAGAGTA
TCGGATGCGCGCCCCTGCGA

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MVILGKSNKQTGPEQWAGEISPASEHLIMRAWEDYLTAEAEEPQVRDIVANSWKRCSAIGIDPQRPGSCAILETVEFERR
LRGSKVLLNAASDILEEANTLFEGTGSMLLLTDVDGVILRAIGDTKTIDAGHDINLVVGADWSENKAGTNGIGTTLASHR
PVLIYGPEHFCSLTKNWTCVGSPVRHPLSGEILGLVDMSGRKCTFQQQHLAFAVMVARRIETVLTVHFEIERRKLLEYSA
QMTRGSWSDGVVIVDRFGKVLSTDEQAPRLLALRATHGERLSASLNAERPLLRPKGDGRSFDLSVSAEYGIDADNVMPVH
HQGELIGAVIIAPRTAPAVATALKQSRAFDPIVTGCATVLDTIQRARRLAAYQAPVLIEGETGVGKELFARAIHDASPCA
SGPFVAFNCGAVSRDLIATELFGYVKGAFTGAATTGNIGRFERANHGTLCLDEIGELPLDLQPFLLRVLEEGTVYRVGDA
TPHPVKVRLIAMTNRDLREEVEKGRFRRDLLYRLNVSTLRVPPLRKRQGDAVLLAQHFLDQLSKKHGFGLRRFAPDVLDL
FKTYGWPGNIRELRNAVESALLLCDTPVIGRGWLPDAILEDHAAQAAPAQPVATQPIFMPPGPMAYEATGYPPGIATPRG
SDLRAMDKAHILSVLERYQWNISLSAGALGIARSTLYRRMQAYGIDMHR

Sequences:

>Translated_689_residues
MVILGKSNKQTGPEQWAGEISPASEHLIMRAWEDYLTAEAEEPQVRDIVANSWKRCSAIGIDPQRPGSCAILETVEFERR
LRGSKVLLNAASDILEEANTLFEGTGSMLLLTDVDGVILRAIGDTKTIDAGHDINLVVGADWSENKAGTNGIGTTLASHR
PVLIYGPEHFCSLTKNWTCVGSPVRHPLSGEILGLVDMSGRKCTFQQQHLAFAVMVARRIETVLTVHFEIERRKLLEYSA
QMTRGSWSDGVVIVDRFGKVLSTDEQAPRLLALRATHGERLSASLNAERPLLRPKGDGRSFDLSVSAEYGIDADNVMPVH
HQGELIGAVIIAPRTAPAVATALKQSRAFDPIVTGCATVLDTIQRARRLAAYQAPVLIEGETGVGKELFARAIHDASPCA
SGPFVAFNCGAVSRDLIATELFGYVKGAFTGAATTGNIGRFERANHGTLCLDEIGELPLDLQPFLLRVLEEGTVYRVGDA
TPHPVKVRLIAMTNRDLREEVEKGRFRRDLLYRLNVSTLRVPPLRKRQGDAVLLAQHFLDQLSKKHGFGLRRFAPDVLDL
FKTYGWPGNIRELRNAVESALLLCDTPVIGRGWLPDAILEDHAAQAAPAQPVATQPIFMPPGPMAYEATGYPPGIATPRG
SDLRAMDKAHILSVLERYQWNISLSAGALGIARSTLYRRMQAYGIDMHR
>Mature_689_residues
MVILGKSNKQTGPEQWAGEISPASEHLIMRAWEDYLTAEAEEPQVRDIVANSWKRCSAIGIDPQRPGSCAILETVEFERR
LRGSKVLLNAASDILEEANTLFEGTGSMLLLTDVDGVILRAIGDTKTIDAGHDINLVVGADWSENKAGTNGIGTTLASHR
PVLIYGPEHFCSLTKNWTCVGSPVRHPLSGEILGLVDMSGRKCTFQQQHLAFAVMVARRIETVLTVHFEIERRKLLEYSA
QMTRGSWSDGVVIVDRFGKVLSTDEQAPRLLALRATHGERLSASLNAERPLLRPKGDGRSFDLSVSAEYGIDADNVMPVH
HQGELIGAVIIAPRTAPAVATALKQSRAFDPIVTGCATVLDTIQRARRLAAYQAPVLIEGETGVGKELFARAIHDASPCA
SGPFVAFNCGAVSRDLIATELFGYVKGAFTGAATTGNIGRFERANHGTLCLDEIGELPLDLQPFLLRVLEEGTVYRVGDA
TPHPVKVRLIAMTNRDLREEVEKGRFRRDLLYRLNVSTLRVPPLRKRQGDAVLLAQHFLDQLSKKHGFGLRRFAPDVLDL
FKTYGWPGNIRELRNAVESALLLCDTPVIGRGWLPDAILEDHAAQAAPAQPVATQPIFMPPGPMAYEATGYPPGIATPRG
SDLRAMDKAHILSVLERYQWNISLSAGALGIARSTLYRRMQAYGIDMHR

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=345, Percent_Identity=42.6086956521739, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1789233, Length=336, Percent_Identity=36.6071428571429, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI87082117, Length=345, Percent_Identity=39.7101449275362, Blast_Score=216, Evalue=5e-57,
Organism=Escherichia coli, GI1790437, Length=312, Percent_Identity=42.6282051282051, Blast_Score=215, Evalue=9e-57,
Organism=Escherichia coli, GI1788905, Length=267, Percent_Identity=43.4456928838951, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI87082152, Length=215, Percent_Identity=52.093023255814, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786524, Length=323, Percent_Identity=43.0340557275542, Blast_Score=207, Evalue=3e-54,
Organism=Escherichia coli, GI1790299, Length=336, Percent_Identity=36.6071428571429, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1789087, Length=339, Percent_Identity=37.1681415929204, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1787583, Length=293, Percent_Identity=38.2252559726962, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87081872, Length=233, Percent_Identity=42.9184549356223, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87081858, Length=670, Percent_Identity=25.8208955223881, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI1789828, Length=214, Percent_Identity=39.2523364485981, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 75398; Mature: 75398

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILGKSNKQTGPEQWAGEISPASEHLIMRAWEDYLTAEAEEPQVRDIVANSWKRCSAIG
CEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHEECC
IDPQRPGSCAILETVEFERRLRGSKVLLNAASDILEEANTLFEGTGSMLLLTDVDGVILR
CCCCCCCCEEEEHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEE
AIGDTKTIDAGHDINLVVGADWSENKAGTNGIGTTLASHRPVLIYGPEHFCSLTKNWTCV
ECCCCCEECCCCCEEEEEECCCCCCCCCCCCCHHHHHCCCCEEEECCHHHHHHCCCCEEE
GSPVRHPLSGEILGLVDMSGRKCTFQQQHLAFAVMVARRIETVLTVHFEIERRKLLEYSA
CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHH
QMTRGSWSDGVVIVDRFGKVLSTDEQAPRLLALRATHGERLSASLNAERPLLRPKGDGRS
HHCCCCCCCCEEEEECCCHHHCCCCCCCEEEEEECCCCCCEECCCCCCCCCCCCCCCCCE
FDLSVSAEYGIDADNVMPVHHQGELIGAVIIAPRTAPAVATALKQSRAFDPIVTGCATVL
EEEEEEECCCCCCCCEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHH
DTIQRARRLAAYQAPVLIEGETGVGKELFARAIHDASPCASGPFVAFNCGAVSRDLIATE
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHH
LFGYVKGAFTGAATTGNIGRFERANHGTLCLDEIGELPLDLQPFLLRVLEEGTVYRVGDA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCHHHHHHHHHCCCCEEEECCC
TPHPVKVRLIAMTNRDLREEVEKGRFRRDLLYRLNVSTLRVPPLRKRQGDAVLLAQHFLD
CCCCEEEEEEEECCHHHHHHHHHCHHHHHHHHEECCCEEECCCCCCCCCCEEHHHHHHHH
QLSKKHGFGLRRFAPDVLDLFKTYGWPGNIRELRNAVESALLLCDTPVIGRGWLPDAILE
HHHHHCCCCHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
DHAAQAAPAQPVATQPIFMPPGPMAYEATGYPPGIATPRGSDLRAMDKAHILSVLERYQW
HHHHCCCCCCCCCCCCEECCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
NISLSAGALGIARSTLYRRMQAYGIDMHR
EEEECCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVILGKSNKQTGPEQWAGEISPASEHLIMRAWEDYLTAEAEEPQVRDIVANSWKRCSAIG
CEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHEECC
IDPQRPGSCAILETVEFERRLRGSKVLLNAASDILEEANTLFEGTGSMLLLTDVDGVILR
CCCCCCCCEEEEHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEE
AIGDTKTIDAGHDINLVVGADWSENKAGTNGIGTTLASHRPVLIYGPEHFCSLTKNWTCV
ECCCCCEECCCCCEEEEEECCCCCCCCCCCCCHHHHHCCCCEEEECCHHHHHHCCCCEEE
GSPVRHPLSGEILGLVDMSGRKCTFQQQHLAFAVMVARRIETVLTVHFEIERRKLLEYSA
CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHH
QMTRGSWSDGVVIVDRFGKVLSTDEQAPRLLALRATHGERLSASLNAERPLLRPKGDGRS
HHCCCCCCCCEEEEECCCHHHCCCCCCCEEEEEECCCCCCEECCCCCCCCCCCCCCCCCE
FDLSVSAEYGIDADNVMPVHHQGELIGAVIIAPRTAPAVATALKQSRAFDPIVTGCATVL
EEEEEEECCCCCCCCEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHH
DTIQRARRLAAYQAPVLIEGETGVGKELFARAIHDASPCASGPFVAFNCGAVSRDLIATE
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHH
LFGYVKGAFTGAATTGNIGRFERANHGTLCLDEIGELPLDLQPFLLRVLEEGTVYRVGDA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCHHHHHHHHHCCCCEEEECCC
TPHPVKVRLIAMTNRDLREEVEKGRFRRDLLYRLNVSTLRVPPLRKRQGDAVLLAQHFLD
CCCCEEEEEEEECCHHHHHHHHHCHHHHHHHHEECCCEEECCCCCCCCCCEEHHHHHHHH
QLSKKHGFGLRRFAPDVLDLFKTYGWPGNIRELRNAVESALLLCDTPVIGRGWLPDAILE
HHHHHCCCCHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
DHAAQAAPAQPVATQPIFMPPGPMAYEATGYPPGIATPRGSDLRAMDKAHILSVLERYQW
HHHHCCCCCCCCCCCCEECCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
NISLSAGALGIARSTLYRRMQAYGIDMHR
EEEECCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA