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The map label for this gene is fabH [H]

Identifier: 182680279

GI number: 182680279

Start: 3832399

End: 3833379

Strand: Reverse

Name: fabH [H]

Synonym: Bind_3379

Alternate gene names: 182680279

Gene position: 3833379-3832399 (Counterclockwise)

Preceding gene: 182680280

Following gene: 182680278

Centisome position: 91.92

GC content: 61.77

Gene sequence:

>981_bases
ATGCCAGGGCAATTGCGCTCGGTCGTGGTCGGGCTCGGCGCTTATCTTCCCAAGCGCATCGTCAGCAATGACGATATCGC
CAAAATGCTCGAGACCTCAGACGACTGGATCGTGCAGCGCACCGGTATCCGGCAGCGCCATGTTGCCGGCGAAGGGGAAC
AGACCTCCGTGCTCGGCCTGCGAGCCGCGCAAGCGGCGCTGGCCGACGCGGGGCTCAGCGGCGCGGATATCGATCTCATC
ATCGTCGCCACATCGACGCCGGATTATACATTCCCGGCGGTCGCGACGCAGATCCAGGCCGCCCTGGGCATGACACATGG
CGCGGCCTTCGATGTGCAAGCCGTCTGCTCCGGTTTCGTCTATGCGGTGACGACAGCCGATAAATTTCTCATTTCCGGTT
CGCATAAACGGGCCTTGGTCATCGGGGCCGAAACCTTTTCCAAACTGCTCGACTGGTCGGATCGCAGCACCTGCGTCCTG
TTCGGTGACGGCGCCGGCGCCATTGTGCTTGAAGCCCGGCCGGGCACAGGAAGGATCAGCGATCGCGGTGTCCTGACCTC
GCAATTGCGCTCGGACGGGCGACATCTCACCAAGCTCTATGTCGATGGCGGGCCCTCGACAACTGGCACCACGGGCCATT
TGCGCATGGCCGGCAGGGAAGTGTTTCGCCATGCGGTCGGCATGGTGAGCGATGTTGTCAATGCCGCCTTCGAGGCCACG
GGCATTACCGGTGCCGATCTCGATTGGTTCGTGCCGCATCAAGCCAACCGGCGAATCATTGAGGCTTCCGCCGAAAAACT
CGGCATTGCTCCGCATAAGGTTGTGGTGACCGTTGATCTGCACGGCAATACTTCGGCCGCGTCGATCCCCCTGGCGCTCG
CCAAGGCGCGTGATGATGGGCGCATCAAACAGGGCGATCTCGTCATGATCGAGGCCATGGGCGGCGGTTTCACTTGGGCT
TCCGCTTTAATTCGTTGGTAA

Upstream 100 bases:

>100_bases
TTGCTCCCGAAAGGGCTGTCCATTAACGGGTTTGATGCTGTAGGACCCTTGCGTAAGGTCCGCGCCTTTGGTCCAGGGAT
TTCCAGACGTGATACAGAAT

Downstream 100 bases:

>100_bases
TCTACTTGTCTTGACTGCTATAAAACTATATAGATATGTTAGATCAAATGGATGCGTTAAGCGGACAGTGTTGCGATCAA
GCTTGCGCGTGTAAATTCGC

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MPGQLRSVVVGLGAYLPKRIVSNDDIAKMLETSDDWIVQRTGIRQRHVAGEGEQTSVLGLRAAQAALADAGLSGADIDLI
IVATSTPDYTFPAVATQIQAALGMTHGAAFDVQAVCSGFVYAVTTADKFLISGSHKRALVIGAETFSKLLDWSDRSTCVL
FGDGAGAIVLEARPGTGRISDRGVLTSQLRSDGRHLTKLYVDGGPSTTGTTGHLRMAGREVFRHAVGMVSDVVNAAFEAT
GITGADLDWFVPHQANRRIIEASAEKLGIAPHKVVVTVDLHGNTSAASIPLALAKARDDGRIKQGDLVMIEAMGGGFTWA
SALIRW

Sequences:

>Translated_326_residues
MPGQLRSVVVGLGAYLPKRIVSNDDIAKMLETSDDWIVQRTGIRQRHVAGEGEQTSVLGLRAAQAALADAGLSGADIDLI
IVATSTPDYTFPAVATQIQAALGMTHGAAFDVQAVCSGFVYAVTTADKFLISGSHKRALVIGAETFSKLLDWSDRSTCVL
FGDGAGAIVLEARPGTGRISDRGVLTSQLRSDGRHLTKLYVDGGPSTTGTTGHLRMAGREVFRHAVGMVSDVVNAAFEAT
GITGADLDWFVPHQANRRIIEASAEKLGIAPHKVVVTVDLHGNTSAASIPLALAKARDDGRIKQGDLVMIEAMGGGFTWA
SALIRW
>Mature_325_residues
PGQLRSVVVGLGAYLPKRIVSNDDIAKMLETSDDWIVQRTGIRQRHVAGEGEQTSVLGLRAAQAALADAGLSGADIDLII
VATSTPDYTFPAVATQIQAALGMTHGAAFDVQAVCSGFVYAVTTADKFLISGSHKRALVIGAETFSKLLDWSDRSTCVLF
GDGAGAIVLEARPGTGRISDRGVLTSQLRSDGRHLTKLYVDGGPSTTGTTGHLRMAGREVFRHAVGMVSDVVNAAFEATG
ITGADLDWFVPHQANRRIIEASAEKLGIAPHKVVVTVDLHGNTSAASIPLALAKARDDGRIKQGDLVMIEAMGGGFTWAS
ALIRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=323, Percent_Identity=46.1300309597523, Blast_Score=296, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34345; Mature: 34213

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGQLRSVVVGLGAYLPKRIVSNDDIAKMLETSDDWIVQRTGIRQRHVAGEGEQTSVLGL
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCCHHHCCCCCCCEEEEEH
RAAQAALADAGLSGADIDLIIVATSTPDYTFPAVATQIQAALGMTHGAAFDVQAVCSGFV
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHCCEE
YAVTTADKFLISGSHKRALVIGAETFSKLLDWSDRSTCVLFGDGAGAIVLEARPGTGRIS
EEEEECCEEEEECCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCC
DRGVLTSQLRSDGRHLTKLYVDGGPSTTGTTGHLRMAGREVFRHAVGMVSDVVNAAFEAT
CCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHC
GITGADLDWFVPHQANRRIIEASAEKLGIAPHKVVVTVDLHGNTSAASIPLALAKARDDG
CCCCCCCEEECCCCCCCEEEECCHHHHCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCC
RIKQGDLVMIEAMGGGFTWASALIRW
CEECCCEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
PGQLRSVVVGLGAYLPKRIVSNDDIAKMLETSDDWIVQRTGIRQRHVAGEGEQTSVLGL
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCCHHHCCCCCCCEEEEEH
RAAQAALADAGLSGADIDLIIVATSTPDYTFPAVATQIQAALGMTHGAAFDVQAVCSGFV
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHCCEE
YAVTTADKFLISGSHKRALVIGAETFSKLLDWSDRSTCVLFGDGAGAIVLEARPGTGRIS
EEEEECCEEEEECCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCC
DRGVLTSQLRSDGRHLTKLYVDGGPSTTGTTGHLRMAGREVFRHAVGMVSDVVNAAFEAT
CCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHC
GITGADLDWFVPHQANRRIIEASAEKLGIAPHKVVVTVDLHGNTSAASIPLALAKARDDG
CCCCCCCEEECCCCCCCEEEECCHHHHCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCC
RIKQGDLVMIEAMGGGFTWASALIRW
CEECCCEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]