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The map label for this gene is purQ [H]

Identifier: 182680024

GI number: 182680024

Start: 3565709

End: 3566407

Strand: Reverse

Name: purQ [H]

Synonym: Bind_3120

Alternate gene names: 182680024

Gene position: 3566407-3565709 (Counterclockwise)

Preceding gene: 182680025

Following gene: 182680023

Centisome position: 85.52

GC content: 58.08

Gene sequence:

>699_bases
ATGAACGCCGCTGTTATCCTGTTTCCCGGTTCGAACCGCGAAAATGACGTCTGCCGCGCGCTTGAACAGGCGAGTGGCAA
GGCGCCCGCGCGCGTCTGGCACGCAGAAGATTACTTGCCTTTAGGCACGGATCTCGTCGTTTTGCCAGGTGGTTTCTCCT
ATGGCGATTATCTGCGCTGCGGTGCGATTGCCGCCCAGGCTCCGATCATGAAGGCAGTCGCCGCTCATGCGGCACGCGGT
GGATTGGTGCTCGGCATTTGCAATGGCTTCCAAATTCTCGTCGAAAGCGGCCTTTTGCCCGGTATTTTGATGCGCAATGC
AAATTTGCGTTTCTTGTGCCGCATGCAGCATCTCAAAATCGAGAGGACCGATACGGCCTTCACTTCCCATTATCGGCCGG
GACAGGTCATCAAGGTCGCGATCGCCCATGGCGAGGGCAATTACGTCGCCGACGAGGACACTCTTGCCCGCCTCGAGGGC
GACGGCCGCGTTGCTTTCCGCTATTGCGATGCGCAGGGCACTTTGGGCGGAGCCGCCAATCCGAACGGCTCGCTGCATGA
CATTGCCGGAATTTATTCGGAAAATTTCAATGTGCTGGGCCTGATGCCGCATCCTGAAAATCTGATCGAGCCGATCATCG
GCGGCACGGATGGGCTGCCCCTTTTTCTCAGCCTCGCGCAATTCAAGAAAGCCGCCTGA

Upstream 100 bases:

>100_bases
ACCACTTTTGGGACCAATCCGATGCGTTTTCAAAGAAACAGAGCCTTGCTCTTGAACGCGTCCGTTGAATGCCGGCGCTG
AGATTGTCCCGAGAATTTCG

Downstream 100 bases:

>100_bases
CGTGAGCGCAGATCCCCCCATCACGCCCGAACTCGTCGCCGCCCATGGCCTAAAGCCCGACGAATATCAGCGCATTCTCA
CCCTTATCGGCCGGGAGCCG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNAAVILFPGSNRENDVCRALEQASGKAPARVWHAEDYLPLGTDLVVLPGGFSYGDYLRCGAIAAQAPIMKAVAAHAARG
GLVLGICNGFQILVESGLLPGILMRNANLRFLCRMQHLKIERTDTAFTSHYRPGQVIKVAIAHGEGNYVADEDTLARLEG
DGRVAFRYCDAQGTLGGAANPNGSLHDIAGIYSENFNVLGLMPHPENLIEPIIGGTDGLPLFLSLAQFKKAA

Sequences:

>Translated_232_residues
MNAAVILFPGSNRENDVCRALEQASGKAPARVWHAEDYLPLGTDLVVLPGGFSYGDYLRCGAIAAQAPIMKAVAAHAARG
GLVLGICNGFQILVESGLLPGILMRNANLRFLCRMQHLKIERTDTAFTSHYRPGQVIKVAIAHGEGNYVADEDTLARLEG
DGRVAFRYCDAQGTLGGAANPNGSLHDIAGIYSENFNVLGLMPHPENLIEPIIGGTDGLPLFLSLAQFKKAA
>Mature_232_residues
MNAAVILFPGSNRENDVCRALEQASGKAPARVWHAEDYLPLGTDLVVLPGGFSYGDYLRCGAIAAQAPIMKAVAAHAARG
GLVLGICNGFQILVESGLLPGILMRNANLRFLCRMQHLKIERTDTAFTSHYRPGQVIKVAIAHGEGNYVADEDTLARLEG
DGRVAFRYCDAQGTLGGAANPNGSLHDIAGIYSENFNVLGLMPHPENLIEPIIGGTDGLPLFLSLAQFKKAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=183, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321498, Length=198, Percent_Identity=31.3131313131313, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582111, Length=181, Percent_Identity=32.5966850828729, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24582109, Length=181, Percent_Identity=32.5966850828729, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17137292, Length=181, Percent_Identity=32.5966850828729, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24726; Mature: 24726

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAVILFPGSNRENDVCRALEQASGKAPARVWHAEDYLPLGTDLVVLPGGFSYGDYLRC
CCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCHHHH
GAIAAQAPIMKAVAAHAARGGLVLGICNGFQILVESGLLPGILMRNANLRFLCRMQHLKI
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHEEHHCCCCCEEEEECCCEEEEEEEEHEEE
ERTDTAFTSHYRPGQVIKVAIAHGEGNYVADEDTLARLEGDGRVAFRYCDAQGTLGGAAN
ECCCCHHHCCCCCCCEEEEEEEECCCCEEECCHHEEEECCCCEEEEEEECCCCCCCCCCC
PNGSLHDIAGIYSENFNVLGLMPHPENLIEPIIGGTDGLPLFLSLAQFKKAA
CCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAAVILFPGSNRENDVCRALEQASGKAPARVWHAEDYLPLGTDLVVLPGGFSYGDYLRC
CCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCHHHH
GAIAAQAPIMKAVAAHAARGGLVLGICNGFQILVESGLLPGILMRNANLRFLCRMQHLKI
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHEEHHCCCCCEEEEECCCEEEEEEEEHEEE
ERTDTAFTSHYRPGQVIKVAIAHGEGNYVADEDTLARLEGDGRVAFRYCDAQGTLGGAAN
ECCCCHHHCCCCCCCEEEEEEEECCCCEEECCHHEEEECCCCEEEEEEECCCCCCCCCCC
PNGSLHDIAGIYSENFNVLGLMPHPENLIEPIIGGTDGLPLFLSLAQFKKAA
CCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]