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The map label for this gene is yajO [H]

Identifier: 182679873

GI number: 182679873

Start: 3370451

End: 3371446

Strand: Reverse

Name: yajO [H]

Synonym: Bind_2963

Alternate gene names: 182679873

Gene position: 3371446-3370451 (Counterclockwise)

Preceding gene: 182679874

Following gene: 182679871

Centisome position: 80.85

GC content: 59.64

Gene sequence:

>996_bases
ATGGATTATGTAAAACTTGGTTCGACTGGTCTCGATGTCTCCCGTCTCTGCTTGGGGTGCATGACCTTCGGTGTTCCAGA
CGCGGGCGTCCACAGTTGGACCCTCGGAGAGGCTGACAGTCGACCGATTATCAAGCGGGCGGTCGAACAGGGGATCAATT
TCTTCGACACCGCAAACAGCTATTCAGCAGGCACCTCCGAGACGATCGTCGGCAAGCTCCTTAAAGAGTTCACCCGCCGC
GAAGAGGTTGTCATCGCGACCAAGGTCTTCTTCCCGGAACGTATGCTGGAGGGCGGCGCCGCTCCCAACCGCAAGGGACT
CTCACGCAAGGCGATCATGACCGAGATCGACGCGAGCCTGACACGTCTTGGAACCGATTACGTTGACCTCTACCAGATTC
ATCGTTGGGACTATGGCACCCCGATCGAAGAGACGATGGAGGCCCTTCACGACATCGTGAAGACCGGGAAGGCACGGTAT
ATCGGCGCCTCCTCAATGTTCGCATGGCAGTTCGCCAAGGCGCAGGAAATTGCGCGGGCAAATGGCTGGACACATTTCGT
CACGATGCAAAACTACATCAACCTGCTCTACCGCGAGGAAGAACGCGAGATGATCCCTCTCTGTAAGGACCAAGGCGTGG
GACTCATACCATGGAGTCCTATGGCCCGTGGCCGGCTGACACGCCCCGCTGGCGAGCAGACAAAACGCAGTGAGAGCGAT
GCTTTCGGCAGGTCGCTCTATGCAGCAACGGAAGACGCGGACAATGCGGTGATCGGCGCGGTCGAGCGCGTGGCTCGTTC
GCGTGGCGTGCCGATGGCACAGGTGGCGCTTGCCTGGGTGCTAGCCAAGCCCGAGGTGTCGGCACCGATCGTGGGCGCGT
CCAAACCTCATCACCTCGACGACGCCATAGCCGCGCTGGAGACTGTGTTGACCGACGACGAGATCGCGGTGCTGGAGGCG
GACTATGTGCCGCATCCTGTCACCGGATTCGAGTGA

Upstream 100 bases:

>100_bases
TCCTCGACCTCGCCACCGAGATGAGAAAATCAACGCGATCCAACTGATCTGTTTTATCTATTCGCGGGCCGAAGCTGGCG
ACACTCACTAAGGAATGACC

Downstream 100 bases:

>100_bases
ACAGATTTTGGTGTCCCCGATGGGAATGCAATCTGTCTTGATGAATTCTGTTAGGGGACTATGGAAAGTTGCTCCATCGC
GCTTGGAGACTTCGCGCCAA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MDYVKLGSTGLDVSRLCLGCMTFGVPDAGVHSWTLGEADSRPIIKRAVEQGINFFDTANSYSAGTSETIVGKLLKEFTRR
EEVVIATKVFFPERMLEGGAAPNRKGLSRKAIMTEIDASLTRLGTDYVDLYQIHRWDYGTPIEETMEALHDIVKTGKARY
IGASSMFAWQFAKAQEIARANGWTHFVTMQNYINLLYREEEREMIPLCKDQGVGLIPWSPMARGRLTRPAGEQTKRSESD
AFGRSLYAATEDADNAVIGAVERVARSRGVPMAQVALAWVLAKPEVSAPIVGASKPHHLDDAIAALETVLTDDEIAVLEA
DYVPHPVTGFE

Sequences:

>Translated_331_residues
MDYVKLGSTGLDVSRLCLGCMTFGVPDAGVHSWTLGEADSRPIIKRAVEQGINFFDTANSYSAGTSETIVGKLLKEFTRR
EEVVIATKVFFPERMLEGGAAPNRKGLSRKAIMTEIDASLTRLGTDYVDLYQIHRWDYGTPIEETMEALHDIVKTGKARY
IGASSMFAWQFAKAQEIARANGWTHFVTMQNYINLLYREEEREMIPLCKDQGVGLIPWSPMARGRLTRPAGEQTKRSESD
AFGRSLYAATEDADNAVIGAVERVARSRGVPMAQVALAWVLAKPEVSAPIVGASKPHHLDDAIAALETVLTDDEIAVLEA
DYVPHPVTGFE
>Mature_331_residues
MDYVKLGSTGLDVSRLCLGCMTFGVPDAGVHSWTLGEADSRPIIKRAVEQGINFFDTANSYSAGTSETIVGKLLKEFTRR
EEVVIATKVFFPERMLEGGAAPNRKGLSRKAIMTEIDASLTRLGTDYVDLYQIHRWDYGTPIEETMEALHDIVKTGKARY
IGASSMFAWQFAKAQEIARANGWTHFVTMQNYINLLYREEEREMIPLCKDQGVGLIPWSPMARGRLTRPAGEQTKRSESD
AFGRSLYAATEDADNAVIGAVERVARSRGVPMAQVALAWVLAKPEVSAPIVGASKPHHLDDAIAALETVLTDDEIAVLEA
DYVPHPVTGFE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=332, Percent_Identity=30.421686746988, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI27436964, Length=332, Percent_Identity=30.421686746988, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI4504825, Length=330, Percent_Identity=30.3030303030303, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI27436962, Length=332, Percent_Identity=30.421686746988, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI27436966, Length=332, Percent_Identity=30.1204819277108, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=32.1212121212121, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI223718702, Length=287, Percent_Identity=26.8292682926829, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI41327764, Length=279, Percent_Identity=27.5985663082437, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41152114, Length=286, Percent_Identity=26.5734265734266, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI223718708, Length=143, Percent_Identity=33.5664335664336, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI87081735, Length=331, Percent_Identity=58.9123867069486, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=32.7635327635328, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=32.4324324324324, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1788070, Length=334, Percent_Identity=31.437125748503, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788081, Length=308, Percent_Identity=30.5194805194805, Blast_Score=109, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=43.026706231454, Blast_Score=268, Evalue=9e-73,
Organism=Saccharomyces cerevisiae, GI6323998, Length=328, Percent_Identity=31.4024390243902, Blast_Score=155, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6319958, Length=286, Percent_Identity=34.6153846153846, Blast_Score=154, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319951, Length=287, Percent_Identity=32.7526132404181, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=32.8125, Blast_Score=132, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6321052, Length=153, Percent_Identity=31.3725490196078, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646155, Length=334, Percent_Identity=31.1377245508982, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24640980, Length=348, Percent_Identity=25.5747126436782, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45549126, Length=348, Percent_Identity=25.5747126436782, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24646159, Length=243, Percent_Identity=32.0987654320988, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36456; Mature: 36456

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYVKLGSTGLDVSRLCLGCMTFGVPDAGVHSWTLGEADSRPIIKRAVEQGINFFDTANS
CCCEECCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCC
YSAGTSETIVGKLLKEFTRREEVVIATKVFFPERMLEGGAAPNRKGLSRKAIMTEIDASL
CCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
TRLGTDYVDLYQIHRWDYGTPIEETMEALHDIVKTGKARYIGASSMFAWQFAKAQEIARA
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
NGWTHFVTMQNYINLLYREEEREMIPLCKDQGVGLIPWSPMARGRLTRPAGEQTKRSESD
CCCEEEEEHHHHHHHHHHHCCHHHCCHHCCCCCEECCCCCCCCCCCCCCCCHHHHCCHHH
AFGRSLYAATEDADNAVIGAVERVARSRGVPMAQVALAWVLAKPEVSAPIVGASKPHHLD
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEECCCCCCCHH
DAIAALETVLTDDEIAVLEADYVPHPVTGFE
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDYVKLGSTGLDVSRLCLGCMTFGVPDAGVHSWTLGEADSRPIIKRAVEQGINFFDTANS
CCCEECCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCC
YSAGTSETIVGKLLKEFTRREEVVIATKVFFPERMLEGGAAPNRKGLSRKAIMTEIDASL
CCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
TRLGTDYVDLYQIHRWDYGTPIEETMEALHDIVKTGKARYIGASSMFAWQFAKAQEIARA
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
NGWTHFVTMQNYINLLYREEEREMIPLCKDQGVGLIPWSPMARGRLTRPAGEQTKRSESD
CCCEEEEEHHHHHHHHHHHCCHHHCCHHCCCCCEECCCCCCCCCCCCCCCCHHHHCCHHH
AFGRSLYAATEDADNAVIGAVERVARSRGVPMAQVALAWVLAKPEVSAPIVGASKPHHLD
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEECCCCCCCHH
DAIAALETVLTDDEIAVLEADYVPHPVTGFE
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]