Click here to switch to the map view.

The map label for this gene is idhA [H]

Identifier: 182679740

GI number: 182679740

Start: 3222703

End: 3223695

Strand: Reverse

Name: idhA [H]

Synonym: Bind_2828

Alternate gene names: 182679740

Gene position: 3223695-3222703 (Counterclockwise)

Preceding gene: 182679741

Following gene: 182679739

Centisome position: 77.3

GC content: 59.92

Gene sequence:

>993_bases
ATGTTGCGGGTTGCTGTCCTTGGTGCTGGACGGATCGGAAGCATTCACGCCGCCAATGTCGTGGCGAATACATCTTCAAA
ACTGGTCGCGATCGCCGACCCTATCGGCGATGCGGCGCGAAATCTGGCGGAGCGCCTTGATTGCGAGGCCTCGCTCGATC
CCATCGCGACGATTGAGCGCGATGACATTGATGCCGTTATCATTGGCACACCGACGGATACACATGTGAGCCTGATGCTG
CATGCCGTCTCGCGTGGCAAGGCGGTTCTGTGCGAAAAACCAATAGACCTCGATATCGTCAAGGTGGACGCCGCGGTGGC
GGACATCAACCGTCTCGGCGGACGGGTCATGCTGGCGTTCAATCGCCGCTTCGATCCCAGCGCCGCAGCGCTGCGCCGCG
CTATCGATGCCGGCGAGGTCGGTAATGTGCATCAGGTCATCATCACCAGCCGGGATCCCGGCCTTGCACCGCGAGAATAT
CTCGCGCATTCGGGCGGCATTTTCCGCGACATGACCATCCATGATTTCGACATGGCCCGTTTCTTCCTGCGTGAAGAACC
GATCGAAGTCATGGCTTTCGGCAGCCGCCTCATCGATCCCACGCTTGAGGAATTCGGCGATTTCGACACGGTCATGGTGC
AGCTGCGGACCGCCTCCGGCAAGCAATGTCATATCAATTGTTCGCGCCAGGCCGTCTACGGTTATGACCAGCGCTTCGAA
ATTTTCGGTTCGGCTGGACAGGTGTTGAACGACAACCTTCGCTCGACGACGATCCGGCGCTGGACGCGGTCGGCGACGGA
AGTCCGCGAACCGCTGATGAACTTTTTCCTCGAACGCTACGCCGACGCCTATCGCCTCGAATTCGAGGCTTTCGCCAAGG
CGGTTCGCGGTAATGGCCCGATGCCCGTGACGGTGCAGGACGGACGTCAGGCGTTGCGGCTTGCCGATTGCGCCCTTGAA
TCGGTTCTCACGGGCCACGCCGTGAAAGTTTGA

Upstream 100 bases:

>100_bases
AGCGCGGCCATTTTCTCCCACAACTCCTCCCCCTTCCATCATCTGCGATCGCCGCACAAGGCGGCGATCGCAAGCTCTTG
GCCAAAATTGGAGTTCCATC

Downstream 100 bases:

>100_bases
ATCCATAACCAGACATTGACAGAAAATATCGAGGAAGACAGTCTCATGCGTGACATCGGCGTTGGTGTGATCGGCACCGG
CTTCATGGGCAAGGCACATG

Product: inositol 2-dehydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI-dehydrogenase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MLRVAVLGAGRIGSIHAANVVANTSSKLVAIADPIGDAARNLAERLDCEASLDPIATIERDDIDAVIIGTPTDTHVSLML
HAVSRGKAVLCEKPIDLDIVKVDAAVADINRLGGRVMLAFNRRFDPSAAALRRAIDAGEVGNVHQVIITSRDPGLAPREY
LAHSGGIFRDMTIHDFDMARFFLREEPIEVMAFGSRLIDPTLEEFGDFDTVMVQLRTASGKQCHINCSRQAVYGYDQRFE
IFGSAGQVLNDNLRSTTIRRWTRSATEVREPLMNFFLERYADAYRLEFEAFAKAVRGNGPMPVTVQDGRQALRLADCALE
SVLTGHAVKV

Sequences:

>Translated_330_residues
MLRVAVLGAGRIGSIHAANVVANTSSKLVAIADPIGDAARNLAERLDCEASLDPIATIERDDIDAVIIGTPTDTHVSLML
HAVSRGKAVLCEKPIDLDIVKVDAAVADINRLGGRVMLAFNRRFDPSAAALRRAIDAGEVGNVHQVIITSRDPGLAPREY
LAHSGGIFRDMTIHDFDMARFFLREEPIEVMAFGSRLIDPTLEEFGDFDTVMVQLRTASGKQCHINCSRQAVYGYDQRFE
IFGSAGQVLNDNLRSTTIRRWTRSATEVREPLMNFFLERYADAYRLEFEAFAKAVRGNGPMPVTVQDGRQALRLADCALE
SVLTGHAVKV
>Mature_330_residues
MLRVAVLGAGRIGSIHAANVVANTSSKLVAIADPIGDAARNLAERLDCEASLDPIATIERDDIDAVIIGTPTDTHVSLML
HAVSRGKAVLCEKPIDLDIVKVDAAVADINRLGGRVMLAFNRRFDPSAAALRRAIDAGEVGNVHQVIITSRDPGLAPREY
LAHSGGIFRDMTIHDFDMARFFLREEPIEVMAFGSRLIDPTLEEFGDFDTVMVQLRTASGKQCHINCSRQAVYGYDQRFE
IFGSAGQVLNDNLRSTTIRRWTRSATEVREPLMNFFLERYADAYRLEFEAFAKAVRGNGPMPVTVQDGRQALRLADCALE
SVLTGHAVKV

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Drosophila melanogaster, GI24581117, Length=256, Percent_Identity=25.78125, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 36194; Mature: 36194

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVAVLGAGRIGSIHAANVVANTSSKLVAIADPIGDAARNLAERLDCEASLDPIATIER
CEEEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCEEEEC
DDIDAVIIGTPTDTHVSLMLHAVSRGKAVLCEKPIDLDIVKVDAAVADINRLGGRVMLAF
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEEHHHHHHHHHCCCEEEEEE
NRRFDPSAAALRRAIDAGEVGNVHQVIITSRDPGLAPREYLAHSGGIFRDMTIHDFDMAR
CCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCEEECEECHHHHHH
FFLREEPIEVMAFGSRLIDPTLEEFGDFDTVMVQLRTASGKQCHINCSRQAVYGYDQRFE
HHHHCCCHHEEECCCHHCCCHHHHHCCCEEEEEEEECCCCCEEEEECCCCEECCCCCCEE
IFGSAGQVLNDNLRSTTIRRWTRSATEVREPLMNFFLERYADAYRLEFEAFAKAVRGNGP
EECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCCC
MPVTVQDGRQALRLADCALESVLTGHAVKV
EEEEECCCHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MLRVAVLGAGRIGSIHAANVVANTSSKLVAIADPIGDAARNLAERLDCEASLDPIATIER
CEEEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCEEEEC
DDIDAVIIGTPTDTHVSLMLHAVSRGKAVLCEKPIDLDIVKVDAAVADINRLGGRVMLAF
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEEHHHHHHHHHCCCEEEEEE
NRRFDPSAAALRRAIDAGEVGNVHQVIITSRDPGLAPREYLAHSGGIFRDMTIHDFDMAR
CCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCEEECEECHHHHHH
FFLREEPIEVMAFGSRLIDPTLEEFGDFDTVMVQLRTASGKQCHINCSRQAVYGYDQRFE
HHHHCCCHHEEECCCHHCCCHHHHHCCCEEEEEEEECCCCCEEEEECCCCEECCCCCCEE
IFGSAGQVLNDNLRSTTIRRWTRSATEVREPLMNFFLERYADAYRLEFEAFAKAVRGNGP
EECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCCC
MPVTVQDGRQALRLADCALESVLTGHAVKV
EEEEECCCHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9802033; 11481431 [H]