Click here to switch to the map view.

The map label for this gene is iolE [H]

Identifier: 182679738

GI number: 182679738

Start: 3220400

End: 3221536

Strand: Reverse

Name: iolE [H]

Synonym: Bind_2826

Alternate gene names: 182679738

Gene position: 3221536-3220400 (Counterclockwise)

Preceding gene: 182679739

Following gene: 182679737

Centisome position: 77.25

GC content: 60.51

Gene sequence:

>1137_bases
ATGTCATCCATGTCCGATCGCAACGCGGCCAAGGCGCCGCTTGGTGGACCTCAGGCGGCTAAGGCCATGCGCACCATCAA
GGGACCCGCGGTTTTTCTCGCCCAATTCGCCGGTGACGCGCCGCCCTTCAATACGCTCGACGGGCTTGCTGGATGGGCGG
CGGAGAAAGGTTTTCTCGGCGTCCAGATTCCGTCCTGGGACCGTCGCCTCTTCGATGTTGAAACTGCGGCGGAGAGCCAG
GATTATTGCGACGAGATCAAGGGCAGGCTTGCTGAACACGGCCTCGTCGTCACCGAGCTTGCAAGCCATCTCCAGGGTCA
GCTCGTCGCCTTGCATCCGGCTTTCGATATTCCGGCCGATTCCTTCGCGGCGCCGGAAGTGCGGGCCAATCCGCAGGCAC
GGCAGGAATGGGCGGTGCGCCAGCTACTTGCGGCGGCCCGCGCTTCGCGCCGGCTCGGGCTTGATCGCCATGTCACCTTC
TCGGGGTCGCTCCTGTGGCCTTATCTCTATCCCTATCCGCAATGGCCGGAGGGGCTGATCAATGATGCCTTTGACGAACT
TGCGCGGCGCTGGCGGCCGATCCTGGACGCCTTCGATGCGGAAGGTGTCGACCTCTGCTACGAAATTCATCCGACCGAAG
ATCTGCATGACGGACTGACGTTCGAGATGTTCCTCGACAGGGTTGATGATCATGCACGCTGCAACATCATGTATGACCCC
AGTCATCTTCTTTTGCAGTCCATGGATTATCTCGCCTACATCGATCATTATCACGACCGCATCAAAATGTTTCATGTCAA
GGATGCGGAGTTCCGGCCGACCGGCAAGACCGGCGCCTATGGCGGCTTCCAGCCCTGGCTCAGCCGCGCGGGTCGTTTCC
GATCTCCGGGCGATGGCCAGATCGATTTTGGGGGCATTTTTTCCAAGCTTGCCGGTTATGGTTTCGACGGCTGGGCCGTG
CTCGAATGGGAATGCTGCCTCAAACATCCCGAGGACGGGGCGGCGGAAGGCGCCGCTTTCATCAAACGCCATATCATCCA
TGTCGCCGAACGCGCCTTTGATGATTTCGTCAAGGCGGATGCGAACCGCGCCGCCAACCGGGCCATTCTCGGCCTTGATG
CGGGAGACCTGTCATGA

Upstream 100 bases:

>100_bases
AGCGGCGCGGACCGGACTTCCGCGAAGCTTGGGAAATTCAGAAGGTCGTCGATACAGCAATCACATCGAGCCGGGCCCGC
GCATGGAAGGAGGTTGCGTA

Downstream 100 bases:

>100_bases
GTGGCGCGGATGATCTTGCGCGCCGCAGATTGCGCCTCGGCATGGTGGGTGGCGGTGAAGGCGCCTATATCGGCGGTATC
CACCGTTTCGCGACACGGCT

Product: xylose isomerase domain-containing protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSSMSDRNAAKAPLGGPQAAKAMRTIKGPAVFLAQFAGDAPPFNTLDGLAGWAAEKGFLGVQIPSWDRRLFDVETAAESQ
DYCDEIKGRLAEHGLVVTELASHLQGQLVALHPAFDIPADSFAAPEVRANPQARQEWAVRQLLAAARASRRLGLDRHVTF
SGSLLWPYLYPYPQWPEGLINDAFDELARRWRPILDAFDAEGVDLCYEIHPTEDLHDGLTFEMFLDRVDDHARCNIMYDP
SHLLLQSMDYLAYIDHYHDRIKMFHVKDAEFRPTGKTGAYGGFQPWLSRAGRFRSPGDGQIDFGGIFSKLAGYGFDGWAV
LEWECCLKHPEDGAAEGAAFIKRHIIHVAERAFDDFVKADANRAANRAILGLDAGDLS

Sequences:

>Translated_378_residues
MSSMSDRNAAKAPLGGPQAAKAMRTIKGPAVFLAQFAGDAPPFNTLDGLAGWAAEKGFLGVQIPSWDRRLFDVETAAESQ
DYCDEIKGRLAEHGLVVTELASHLQGQLVALHPAFDIPADSFAAPEVRANPQARQEWAVRQLLAAARASRRLGLDRHVTF
SGSLLWPYLYPYPQWPEGLINDAFDELARRWRPILDAFDAEGVDLCYEIHPTEDLHDGLTFEMFLDRVDDHARCNIMYDP
SHLLLQSMDYLAYIDHYHDRIKMFHVKDAEFRPTGKTGAYGGFQPWLSRAGRFRSPGDGQIDFGGIFSKLAGYGFDGWAV
LEWECCLKHPEDGAAEGAAFIKRHIIHVAERAFDDFVKADANRAANRAILGLDAGDLS
>Mature_377_residues
SSMSDRNAAKAPLGGPQAAKAMRTIKGPAVFLAQFAGDAPPFNTLDGLAGWAAEKGFLGVQIPSWDRRLFDVETAAESQD
YCDEIKGRLAEHGLVVTELASHLQGQLVALHPAFDIPADSFAAPEVRANPQARQEWAVRQLLAAARASRRLGLDRHVTFS
GSLLWPYLYPYPQWPEGLINDAFDELARRWRPILDAFDAEGVDLCYEIHPTEDLHDGLTFEMFLDRVDDHARCNIMYDPS
HLLLQSMDYLAYIDHYHDRIKMFHVKDAEFRPTGKTGAYGGFQPWLSRAGRFRSPGDGQIDFGGIFSKLAGYGFDGWAVL
EWECCLKHPEDGAAEGAAFIKRHIIHVAERAFDDFVKADANRAANRAILGLDAGDLS

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 41989; Mature: 41857

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSMSDRNAAKAPLGGPQAAKAMRTIKGPAVFLAQFAGDAPPFNTLDGLAGWAAEKGFLG
CCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEE
VQIPSWDRRLFDVETAAESQDYCDEIKGRLAEHGLVVTELASHLQGQLVALHPAFDIPAD
EECCCCCCCEEEHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCC
SFAAPEVRANPQARQEWAVRQLLAAARASRRLGLDRHVTFSGSLLWPYLYPYPQWPEGLI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECCEECCCCCCCHHHH
NDAFDELARRWRPILDAFDAEGVDLCYEIHPTEDLHDGLTFEMFLDRVDDHARCNIMYDP
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCCHHHHHHHHCCCCCEEEEEECC
SHLLLQSMDYLAYIDHYHDRIKMFHVKDAEFRPTGKTGAYGGFQPWLSRAGRFRSPGDGQ
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
IDFGGIFSKLAGYGFDGWAVLEWECCLKHPEDGAAEGAAFIKRHIIHVAERAFDDFVKAD
EEHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRAANRAILGLDAGDLS
HHHHHCCEEEECCCCCCC
>Mature Secondary Structure 
SSMSDRNAAKAPLGGPQAAKAMRTIKGPAVFLAQFAGDAPPFNTLDGLAGWAAEKGFLG
CCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEE
VQIPSWDRRLFDVETAAESQDYCDEIKGRLAEHGLVVTELASHLQGQLVALHPAFDIPAD
EECCCCCCCEEEHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCC
SFAAPEVRANPQARQEWAVRQLLAAARASRRLGLDRHVTFSGSLLWPYLYPYPQWPEGLI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECCEECCCCCCCHHHH
NDAFDELARRWRPILDAFDAEGVDLCYEIHPTEDLHDGLTFEMFLDRVDDHARCNIMYDP
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCCHHHHHHHHCCCCCEEEEEECC
SHLLLQSMDYLAYIDHYHDRIKMFHVKDAEFRPTGKTGAYGGFQPWLSRAGRFRSPGDGQ
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
IDFGGIFSKLAGYGFDGWAVLEWECCLKHPEDGAAEGAAFIKRHIIHVAERAFDDFVKAD
EEHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRAANRAILGLDAGDLS
HHHHHCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA