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The map label for this gene is czcR [H]

Identifier: 182679485

GI number: 182679485

Start: 2895229

End: 2896119

Strand: Reverse

Name: czcR [H]

Synonym: Bind_2540

Alternate gene names: 182679485

Gene position: 2896119-2895229 (Counterclockwise)

Preceding gene: 182679491

Following gene: 182679481

Centisome position: 69.45

GC content: 59.82

Gene sequence:

>891_bases
ATGGATACGCGTTTTCTGGAGTGTTTCGTTGCCGTTGCCGAGTCTGGTTCCGTCGCGGAAGCCGCGCGGCGGCTTAATAT
CGCCCCGACCACACTCGCATTGCGAATTCGCGCTCTAGAGGACGAACTCGGCTTCGCTCTCGTGACTCGTTCGGGGCGCA
CCGCCAGGCCGACACCGGCGGGCGAGGCGCTTGCCCTCCGGGCGACAGGGATTTTGCACGACCTACGAGACCTCAAAACA
TTGCAGGATGAGGAAAAGCCTCGGGGACAGCTCCGACTTGGTGTCGCGCAAACGGCAATAACCACTGTATTGTGCGACGT
CCTTCCTGCCCTTGCGCAGAAATACCCGGACCTTGAAATTATCGTCCAGAAGGGCTCGTCCGCCCAGGTATATGGTAAAC
TGAACAATGCAGAGGTGGAGGCGGCCTTTCTGTTCCATCCGCCATTCAGGCTGCCGAAGAGTCTCGTATGGAGGTCGCTA
CGAGCTGAGCGCTACGTCGTTATTGCATCCGCTGCCGAAGCCTGTGACGATCCACTCCAGCTTCTGCGAGACCGGCCCCT
CGTACGTTACGATCGCTCTTTGTGGTCGGGCCAAATCGCTGAAAACTACCTGAGACAACAGCGTATCCGGCCGAAAGACC
GCATCGAACTCGACGCGCTTGATGCTATCGCCGTACTTGTCAATCACGGCATCGGCGTTTCGCTGGTGCCGGACCGCGCG
CTGCCGTGGCCCGAGGGGTTGACGATCACGAAACATCCTCTTCCCGAGCCGGCGCCACAGCGTGAGCTAGGCTTGCTTTG
GCCAATCACCTCGGCTCATGCGCGGCTCATCCGGATCGTGGAACAGGAAACCGTTCGCGCAATCGGTGGTGCGCCAGGGG
CTGTTTGTTGA

Upstream 100 bases:

>100_bases
TCCGGACCGGCCGGAACACTTCTTGACGATGATTTTGGAGCAGTGGAGAGCGCAAAAAAACTGTGTAATATATGAATTTA
AATCACAGGAATCCTGAGTA

Downstream 100 bases:

>100_bases
TTTCTCAGAGTTGATCCGGGGGAAACCGGAAATGACCGAAGCGTCACGTCTGCCCCTCATCCCAGGGATTGATGACGGAG
GCCCCGGTATCCTGGAAATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDTRFLECFVAVAESGSVAEAARRLNIAPTTLALRIRALEDELGFALVTRSGRTARPTPAGEALALRATGILHDLRDLKT
LQDEEKPRGQLRLGVAQTAITTVLCDVLPALAQKYPDLEIIVQKGSSAQVYGKLNNAEVEAAFLFHPPFRLPKSLVWRSL
RAERYVVIASAAEACDDPLQLLRDRPLVRYDRSLWSGQIAENYLRQQRIRPKDRIELDALDAIAVLVNHGIGVSLVPDRA
LPWPEGLTITKHPLPEPAPQRELGLLWPITSAHARLIRIVEQETVRAIGGAPGAVC

Sequences:

>Translated_296_residues
MDTRFLECFVAVAESGSVAEAARRLNIAPTTLALRIRALEDELGFALVTRSGRTARPTPAGEALALRATGILHDLRDLKT
LQDEEKPRGQLRLGVAQTAITTVLCDVLPALAQKYPDLEIIVQKGSSAQVYGKLNNAEVEAAFLFHPPFRLPKSLVWRSL
RAERYVVIASAAEACDDPLQLLRDRPLVRYDRSLWSGQIAENYLRQQRIRPKDRIELDALDAIAVLVNHGIGVSLVPDRA
LPWPEGLTITKHPLPEPAPQRELGLLWPITSAHARLIRIVEQETVRAIGGAPGAVC
>Mature_296_residues
MDTRFLECFVAVAESGSVAEAARRLNIAPTTLALRIRALEDELGFALVTRSGRTARPTPAGEALALRATGILHDLRDLKT
LQDEEKPRGQLRLGVAQTAITTVLCDVLPALAQKYPDLEIIVQKGSSAQVYGKLNNAEVEAAFLFHPPFRLPKSLVWRSL
RAERYVVIASAAEACDDPLQLLRDRPLVRYDRSLWSGQIAENYLRQQRIRPKDRIELDALDAIAVLVNHGIGVSLVPDRA
LPWPEGLTITKHPLPEPAPQRELGLLWPITSAHARLIRIVEQETVRAIGGAPGAVC

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=287, Percent_Identity=27.5261324041812, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI157672245, Length=262, Percent_Identity=27.8625954198473, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787806, Length=147, Percent_Identity=29.2517006802721, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790208, Length=249, Percent_Identity=27.710843373494, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI145693105, Length=279, Percent_Identity=27.2401433691756, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787589, Length=117, Percent_Identity=34.1880341880342, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=25.7028112449799, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787879, Length=284, Percent_Identity=25.7042253521127, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788887, Length=282, Percent_Identity=25.531914893617, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367136, Length=255, Percent_Identity=24.7058823529412, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788748, Length=250, Percent_Identity=25.6, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082132, Length=246, Percent_Identity=26.4227642276423, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32580; Mature: 32580

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTRFLECFVAVAESGSVAEAARRLNIAPTTLALRIRALEDELGFALVTRSGRTARPTPA
CCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHEEEHHHHHCCEEEEECCCCCCCCCCC
GEALALRATGILHDLRDLKTLQDEEKPRGQLRLGVAQTAITTVLCDVLPALAQKYPDLEI
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IVQKGSSAQVYGKLNNAEVEAAFLFHPPFRLPKSLVWRSLRAERYVVIASAAEACDDPLQ
EEECCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHCCCEEEEEECCHHHCCHHHH
LLRDRPLVRYDRSLWSGQIAENYLRQQRIRPKDRIELDALDAIAVLVNHGIGVSLVPDRA
HHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCCEEECCCCC
LPWPEGLTITKHPLPEPAPQRELGLLWPITSAHARLIRIVEQETVRAIGGAPGAVC
CCCCCCCEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDTRFLECFVAVAESGSVAEAARRLNIAPTTLALRIRALEDELGFALVTRSGRTARPTPA
CCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHEEEHHHHHCCEEEEECCCCCCCCCCC
GEALALRATGILHDLRDLKTLQDEEKPRGQLRLGVAQTAITTVLCDVLPALAQKYPDLEI
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IVQKGSSAQVYGKLNNAEVEAAFLFHPPFRLPKSLVWRSLRAERYVVIASAAEACDDPLQ
EEECCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHCCCEEEEEECCHHHCCHHHH
LLRDRPLVRYDRSLWSGQIAENYLRQQRIRPKDRIELDALDAIAVLVNHGIGVSLVPDRA
HHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCCEEECCCCC
LPWPEGLTITKHPLPEPAPQRELGLLWPITSAHARLIRIVEQETVRAIGGAPGAVC
CCCCCCCEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9099864; 9308178; 9384377 [H]