Click here to switch to the map view.

The map label for this gene is sigW [H]

Identifier: 182679454

GI number: 182679454

Start: 2857118

End: 2858173

Strand: Reverse

Name: sigW [H]

Synonym: Bind_2504

Alternate gene names: 182679454

Gene position: 2858173-2857118 (Counterclockwise)

Preceding gene: 182679455

Following gene: 182679443

Centisome position: 68.54

GC content: 62.31

Gene sequence:

>1056_bases
ATGACGAAATTCGAACGATCCAATGAGCAGGATACGGCAGCGGTTGCTCGCCGAAGGTTCGAGGCATTGGCCGAACCGTT
CCGCCAGGAAATTCGGCTCCATTGTTATCGCATGTTAGGCTCCGTGCATGAAGCCGAGGATCTCGTCCAGCAGACTTTCC
TGTATGCTTGGCGAGGATTCGATCGCTACGAAGAATGTGGCTCGTTTCGCGCTTGGCTCTACCAGATCGCGACCAATGCC
TGCTTGAACGCACTCGCCATCCGCAGAAATGCCCGACGCTATCTGCCGGAGGCATTGGGCCCTGCGACGACCGATATGCC
GGACGGAAAGGCCACGCCTGATATTCTGTATGTGGAACCTTTTCCGGACTCCTATCTCGATGAGATCGCCGATGAGGCGC
CGACACCGGAGGCGGCCTATGCCTCCAGCGAAGCGGTGCGGCTCGCTTTCGTGGCCGCGATCCAGGACCTGCCGCCCAGC
CAGCGTGCCGTGCTTCTTTTGCGCGATGTGCTGGGTTGGTCCGCCATCGAGACGGCCAACCTGCTGGGCGGATCTGTTGT
CTCCATCAACAGCGCCCTCCAGCGGGCGCGCAAGACCCTCGCCACGCGCTATCCGAAGGGGCGCCCGGCATCGGGTGCCC
CGCAGGGGGCGCGGGAGGAGGCACTTCTTCGACGCTATCTGAATGCTTGGGAACAGCTGGACGTCGACGAGTTAACTGCG
CTTCTGAAGGAGGAGGCGACCTATACGATGCCGCCGCTGCCGCAGTGGTATGCCGGGCGAGAGGCGATCCGGGCCTTCTT
CTCCTGGGCCTGGCAGCTCTACAAAGGCTTCAAACTCGTGCGGACCGCAGCCAATGGGCAGCCAGCCTTCGCTGCCTATG
CCCGCGCCGAGGCGGGGGCGCCATGGCAAGCGCATTCCCTCCACCTGCTGACCCTCGCGGATGGGTTGATTGCGGGGCTG
ACAGTCTTCTACAAGCCCGATGGCCCACAACTCTTTGCCGCTTTCAGGCTTCCGGCGAGCCTACCACCGGACCGTCCATT
CGACCGGGAATCGTAA

Upstream 100 bases:

>100_bases
CGTCGTCTCCCTTCTAACGCAGCCGGACCGGCACAAAGAGCACGCATTCATCGTTTCAGGGAAAGGGCTTGAGGCCGTGG
CCGGGTAGGGGCTGATCCAG

Downstream 100 bases:

>100_bases
GCAGTTGCGGCAGCGGTCTCGGAGCCAAGTCCTCGCGGCGTCAGCTCCGTTCGATGGTGACGGCTGCCTGATCCAAGGCT
TCGGCGATAGCCTGGGCTTC

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTKFERSNEQDTAAVARRRFEALAEPFRQEIRLHCYRMLGSVHEAEDLVQQTFLYAWRGFDRYEECGSFRAWLYQIATNA
CLNALAIRRNARRYLPEALGPATTDMPDGKATPDILYVEPFPDSYLDEIADEAPTPEAAYASSEAVRLAFVAAIQDLPPS
QRAVLLLRDVLGWSAIETANLLGGSVVSINSALQRARKTLATRYPKGRPASGAPQGAREEALLRRYLNAWEQLDVDELTA
LLKEEATYTMPPLPQWYAGREAIRAFFSWAWQLYKGFKLVRTAANGQPAFAAYARAEAGAPWQAHSLHLLTLADGLIAGL
TVFYKPDGPQLFAAFRLPASLPPDRPFDRES

Sequences:

>Translated_351_residues
MTKFERSNEQDTAAVARRRFEALAEPFRQEIRLHCYRMLGSVHEAEDLVQQTFLYAWRGFDRYEECGSFRAWLYQIATNA
CLNALAIRRNARRYLPEALGPATTDMPDGKATPDILYVEPFPDSYLDEIADEAPTPEAAYASSEAVRLAFVAAIQDLPPS
QRAVLLLRDVLGWSAIETANLLGGSVVSINSALQRARKTLATRYPKGRPASGAPQGAREEALLRRYLNAWEQLDVDELTA
LLKEEATYTMPPLPQWYAGREAIRAFFSWAWQLYKGFKLVRTAANGQPAFAAYARAEAGAPWQAHSLHLLTLADGLIAGL
TVFYKPDGPQLFAAFRLPASLPPDRPFDRES
>Mature_350_residues
TKFERSNEQDTAAVARRRFEALAEPFRQEIRLHCYRMLGSVHEAEDLVQQTFLYAWRGFDRYEECGSFRAWLYQIATNAC
LNALAIRRNARRYLPEALGPATTDMPDGKATPDILYVEPFPDSYLDEIADEAPTPEAAYASSEAVRLAFVAAIQDLPPSQ
RAVLLLRDVLGWSAIETANLLGGSVVSINSALQRARKTLATRYPKGRPASGAPQGAREEALLRRYLNAWEQLDVDELTAL
LKEEATYTMPPLPQWYAGREAIRAFFSWAWQLYKGFKLVRTAANGQPAFAAYARAEAGAPWQAHSLHLLTLADGLIAGLT
VFYKPDGPQLFAAFRLPASLPPDRPFDRES

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 39258; Mature: 39127

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFERSNEQDTAAVARRRFEALAEPFRQEIRLHCYRMLGSVHEAEDLVQQTFLYAWRGF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DRYEECGSFRAWLYQIATNACLNALAIRRNARRYLPEALGPATTDMPDGKATPDILYVEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECC
FPDSYLDEIADEAPTPEAAYASSEAVRLAFVAAIQDLPPSQRAVLLLRDVLGWSAIETAN
CCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LLGGSVVSINSALQRARKTLATRYPKGRPASGAPQGAREEALLRRYLNAWEQLDVDELTA
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
LLKEEATYTMPPLPQWYAGREAIRAFFSWAWQLYKGFKLVRTAANGQPAFAAYARAEAGA
HHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
PWQAHSLHLLTLADGLIAGLTVFYKPDGPQLFAAFRLPASLPPDRPFDRES
CCCCCCEEHHHHHHHHHHCEEEEECCCCCCEEHEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKFERSNEQDTAAVARRRFEALAEPFRQEIRLHCYRMLGSVHEAEDLVQQTFLYAWRGF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DRYEECGSFRAWLYQIATNACLNALAIRRNARRYLPEALGPATTDMPDGKATPDILYVEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECC
FPDSYLDEIADEAPTPEAAYASSEAVRLAFVAAIQDLPPSQRAVLLLRDVLGWSAIETAN
CCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LLGGSVVSINSALQRARKTLATRYPKGRPASGAPQGAREEALLRRYLNAWEQLDVDELTA
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
LLKEEATYTMPPLPQWYAGREAIRAFFSWAWQLYKGFKLVRTAANGQPAFAAYARAEAGA
HHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
PWQAHSLHLLTLADGLIAGLTVFYKPDGPQLFAAFRLPASLPPDRPFDRES
CCCCCCEEHHHHHHHHHHCEEEEECCCCCCEEHEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]