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The map label for this gene is feaR [H]

Identifier: 182679443

GI number: 182679443

Start: 2845881

End: 2846831

Strand: Reverse

Name: feaR [H]

Synonym: Bind_2493

Alternate gene names: 182679443

Gene position: 2846831-2845881 (Counterclockwise)

Preceding gene: 182679454

Following gene: 182679442

Centisome position: 68.27

GC content: 49.74

Gene sequence:

>951_bases
ATGAGGTTTAAAATCGGTTCTCTAGACTCCTCGCTCGTGCCCCATTCGCATAGCATTAATTATTGGGAGGAGGCGCTCGC
TGCTTTGTGCGGCCGTCTGCAAGTAGAGATCGTCGGAGATGACAGAATAGATGCCTTTGCGAACTATGTCGATTTTGACG
GGCTCAGGCTTTGTCAAATCAAAACCAGTGGACATAGGGTAGCGCTTCCCAGATCATGGCTCGGTCAATCAGAACATCCG
GTCGTCAAGGTGCATTTTCAGACCAAGGGAACGTCAATATTCGAGCAGGGTCAGACGAGGATTGTACTCTCGCCCGGGGA
TTGTCTTGCCTATGATGTTGCGCAACCGCACCTCATCTCTAGCTTGGAATATACTGAGCACGAAGTCGCAATCATACCCA
AGAAAAGTTTGATGGAACGCCGAATTGCTGCTCGGCAATTTCCAGCAGTCCATATGTCCACGGAGCATGGTGACATTCGC
TTCGTACGAAATTTTCTCCTTTCAGCCTTGCGGCAGGCCTCGACACTTTCGAATAAGTCCATCAAGCCCATCGCGGACGC
CCTCTTGGATGTGCTCATCATCCCTCTTTCCGAAGGACGACCTCAAGGCGTCTCGAGCGATAGGCGTGAGACATTAAGAA
TTCGGGCACAAGATTATATTCGGCAGAATTTGGGCGACACTGATTTGACGATCGATCGCATCGCCCGCGCGTTAGGTTGC
AGCAAGCGCTATTTGCATATGATTTTCATGGATGAAGGAATAACCGTAAGCAGGTTTATTTGGAACGAGAGACTCGATAG
ATGTTTCTATGATCTCAAGGATGCGCATCAATCGAACAAGACGATTACTGAGGTCGCGATCGAATGGGGCTTCAGCAGCC
CATCCCATTTCAGTCGATCGTTCAAGGACCGTTACGGATTCACGCCATCTACGGCTTTGAAGCGCATATAG

Upstream 100 bases:

>100_bases
CTTGCTTTGCAACGAACTTGCTTGCCTCAGGGCGAAAAATGACGCTAAATTTTTCCGAAAGCCCCGATCGATGAGGGCTG
AAAGGCACGAGTATTCGGGC

Downstream 100 bases:

>100_bases
AAGCCCGGCTTTCGATATCGGCCATGTCTTTATCCGGTCCTCGTAATCACGCTCCTGGGTTAGGCTTGGTCACCAAAAAG
CTTGGCGGTGACTGACCTTA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRFKIGSLDSSLVPHSHSINYWEEALAALCGRLQVEIVGDDRIDAFANYVDFDGLRLCQIKTSGHRVALPRSWLGQSEHP
VVKVHFQTKGTSIFEQGQTRIVLSPGDCLAYDVAQPHLISSLEYTEHEVAIIPKKSLMERRIAARQFPAVHMSTEHGDIR
FVRNFLLSALRQASTLSNKSIKPIADALLDVLIIPLSEGRPQGVSSDRRETLRIRAQDYIRQNLGDTDLTIDRIARALGC
SKRYLHMIFMDEGITVSRFIWNERLDRCFYDLKDAHQSNKTITEVAIEWGFSSPSHFSRSFKDRYGFTPSTALKRI

Sequences:

>Translated_316_residues
MRFKIGSLDSSLVPHSHSINYWEEALAALCGRLQVEIVGDDRIDAFANYVDFDGLRLCQIKTSGHRVALPRSWLGQSEHP
VVKVHFQTKGTSIFEQGQTRIVLSPGDCLAYDVAQPHLISSLEYTEHEVAIIPKKSLMERRIAARQFPAVHMSTEHGDIR
FVRNFLLSALRQASTLSNKSIKPIADALLDVLIIPLSEGRPQGVSSDRRETLRIRAQDYIRQNLGDTDLTIDRIARALGC
SKRYLHMIFMDEGITVSRFIWNERLDRCFYDLKDAHQSNKTITEVAIEWGFSSPSHFSRSFKDRYGFTPSTALKRI
>Mature_316_residues
MRFKIGSLDSSLVPHSHSINYWEEALAALCGRLQVEIVGDDRIDAFANYVDFDGLRLCQIKTSGHRVALPRSWLGQSEHP
VVKVHFQTKGTSIFEQGQTRIVLSPGDCLAYDVAQPHLISSLEYTEHEVAIIPKKSLMERRIAARQFPAVHMSTEHGDIR
FVRNFLLSALRQASTLSNKSIKPIADALLDVLIIPLSEGRPQGVSSDRRETLRIRAQDYIRQNLGDTDLTIDRIARALGC
SKRYLHMIFMDEGITVSRFIWNERLDRCFYDLKDAHQSNKTITEVAIEWGFSSPSHFSRSFKDRYGFTPSTALKRI

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=295, Percent_Identity=24.7457627118644, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35930; Mature: 35930

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFKIGSLDSSLVPHSHSINYWEEALAALCGRLQVEIVGDDRIDAFANYVDFDGLRLCQI
CCEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCEEEEEE
KTSGHRVALPRSWLGQSEHPVVKVHFQTKGTSIFEQGQTRIVLSPGDCLAYDVAQPHLIS
ECCCCEEECCHHHCCCCCCCEEEEEEECCCCHHHHCCCEEEEECCCCEEEECCCCCHHHH
SLEYTEHEVAIIPKKSLMERRIAARQFPAVHMSTEHGDIRFVRNFLLSALRQASTLSNKS
CCCCCCCEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
IKPIADALLDVLIIPLSEGRPQGVSSDRRETLRIRAQDYIRQNLGDTDLTIDRIARALGC
CHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
SKRYLHMIFMDEGITVSRFIWNERLDRCFYDLKDAHQSNKTITEVAIEWGFSSPSHFSRS
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHEECCCCCHHHHHHH
FKDRYGFTPSTALKRI
HHHHCCCCHHHHHHCC
>Mature Secondary Structure
MRFKIGSLDSSLVPHSHSINYWEEALAALCGRLQVEIVGDDRIDAFANYVDFDGLRLCQI
CCEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCEEEEEE
KTSGHRVALPRSWLGQSEHPVVKVHFQTKGTSIFEQGQTRIVLSPGDCLAYDVAQPHLIS
ECCCCEEECCHHHCCCCCCCEEEEEEECCCCHHHHCCCEEEEECCCCEEEECCCCCHHHH
SLEYTEHEVAIIPKKSLMERRIAARQFPAVHMSTEHGDIRFVRNFLLSALRQASTLSNKS
CCCCCCCEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
IKPIADALLDVLIIPLSEGRPQGVSSDRRETLRIRAQDYIRQNLGDTDLTIDRIARALGC
CHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
SKRYLHMIFMDEGITVSRFIWNERLDRCFYDLKDAHQSNKTITEVAIEWGFSSPSHFSRS
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHEECCCCCHHHHHHH
FKDRYGFTPSTALKRI
HHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]