BacMap

Definition	Beijerinckia indica subsp. indica ATCC 9039 chromosome, complete genome.
Accession	NC_010581
Length	4,170,153

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The map label for this gene is ppi [H]

Identifier: 182679299

GI number: 182679299

Start: 2680213

End: 2680800

Strand: Reverse

Name: ppi [H]

Synonym: Bind_2343

Alternate gene names: 182679299

Gene position: 2680800-2680213 (Counterclockwise)

Preceding gene: 182679300

Following gene: 182679298

Centisome position: 64.29

GC content: 55.1

Gene sequence:

>588_bases
ATGTCAAAATCCAACATTTTTCAACGACGGATGTTTTGTCTTCTGCTCGCCGCTTTGCCCGTCCTCGGCATGGCTGGTGA
GATGGCCTCGGCTGCCAAGGCGGCGGCTCCAGATCCGTATCACACGGTCTATCTCGACACCAAGGATGGCCGCATCACCA
TCGCGCTGCGGCCCGATCTCGCTCCGAAAACCGTTGCTCAGATCGAGACTTTGACGCGGCGTGGCTTTTATGACGGCATT
GTCTTCCATCGGGTGATCGATGGTTTCATGGCTCAGACGGGTGATCCGACCGGCACCGGCACCGGCAAATCCGATTTGCC
GAATGTTCCGGCTGAATTCACCTCAACGCCCTTTAAGCGCGGCACGGTCGGCATGGCCAGGGCGCAAGATCCCAATTCCG
GCAATTCGCAATTTTTCATCACGTTCGCGGACGCCGATTTTCTCAACAATCAATATACAGTCGTAGGGCAGGTCGTGTCC
GGCATGGATGTCGTCGACAAGATCAAGAAGGGATCGTCCAGCAATAATGGCTCGGTCAGCAATCCCGACAAGATCATCAA
GATGCGTATGGCCGACCAAGAGAAATAA

Upstream 100 bases:

>100_bases
GGCGGCGATGCCTCGCCCTTTGTACCCCCCGTCGTCGCGGCGGCGCTTGCTCAGAAAACCAGCCTTCCATCGTGAAACTG
CCGAGGAGATCTTCAGGTCA

Downstream 100 bases:

>100_bases
AGATCAAAGAGAGTGCAAACGCGTTTCAATGAGCGGATCGTCTGGATCCGCTCATTTTAAGATTATCGAGGCAAAGGTCT
CGGGTCGATTTTTTGTGAAG

Product: peptidyl-prolyl cis-trans isomerase cyclophilin type

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSKSNIFQRRMFCLLLAALPVLGMAGEMASAAKAAAPDPYHTVYLDTKDGRITIALRPDLAPKTVAQIETLTRRGFYDGI
VFHRVIDGFMAQTGDPTGTGTGKSDLPNVPAEFTSTPFKRGTVGMARAQDPNSGNSQFFITFADADFLNNQYTVVGQVVS
GMDVVDKIKKGSSSNNGSVSNPDKIIKMRMADQEK

Sequences:

>Translated_195_residues
MSKSNIFQRRMFCLLLAALPVLGMAGEMASAAKAAAPDPYHTVYLDTKDGRITIALRPDLAPKTVAQIETLTRRGFYDGI
VFHRVIDGFMAQTGDPTGTGTGKSDLPNVPAEFTSTPFKRGTVGMARAQDPNSGNSQFFITFADADFLNNQYTVVGQVVS
GMDVVDKIKKGSSSNNGSVSNPDKIIKMRMADQEK
>Mature_194_residues
SKSNIFQRRMFCLLLAALPVLGMAGEMASAAKAAAPDPYHTVYLDTKDGRITIALRPDLAPKTVAQIETLTRRGFYDGIV
FHRVIDGFMAQTGDPTGTGTGKSDLPNVPAEFTSTPFKRGTVGMARAQDPNSGNSQFFITFADADFLNNQYTVVGQVVSG
MDVVDKIKKGSSSNNGSVSNPDKIIKMRMADQEK

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI24308049, Length=150, Percent_Identity=40.6666666666667, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI7706339, Length=160, Percent_Identity=36.25, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI19557636, Length=133, Percent_Identity=39.0977443609023, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI64276486, Length=121, Percent_Identity=42.9752066115703, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI5031987, Length=149, Percent_Identity=40.9395973154362, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI22547212, Length=134, Percent_Identity=40.2985074626866, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI7657473, Length=134, Percent_Identity=40.2985074626866, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI22547215, Length=134, Percent_Identity=40.2985074626866, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI45439316, Length=159, Percent_Identity=36.4779874213836, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI10863927, Length=133, Percent_Identity=36.8421052631579, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI4505991, Length=189, Percent_Identity=34.3915343915344, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI4758950, Length=179, Percent_Identity=36.3128491620112, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI303305009, Length=172, Percent_Identity=35.4651162790698, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI5174637, Length=160, Percent_Identity=35.625, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI256017253, Length=128, Percent_Identity=37.5, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI221139811, Length=128, Percent_Identity=37.5, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI256017251, Length=128, Percent_Identity=37.5, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI310110104, Length=133, Percent_Identity=35.3383458646617, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI310129267, Length=133, Percent_Identity=34.5864661654135, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI310120620, Length=133, Percent_Identity=34.5864661654135, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI178057341, Length=131, Percent_Identity=35.8778625954198, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI310127646, Length=128, Percent_Identity=34.375, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI310114371, Length=128, Percent_Identity=34.375, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI310119221, Length=128, Percent_Identity=34.375, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI5454154, Length=134, Percent_Identity=34.3283582089552, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI169163387, Length=133, Percent_Identity=34.5864661654135, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI20911035, Length=138, Percent_Identity=34.0579710144928, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI169164185, Length=133, Percent_Identity=34.5864661654135, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI169163623, Length=133, Percent_Identity=34.5864661654135, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1789763, Length=177, Percent_Identity=38.4180790960452, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1786736, Length=166, Percent_Identity=39.1566265060241, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17506311, Length=136, Percent_Identity=44.8529411764706, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17539496, Length=144, Percent_Identity=37.5, Blast_Score=93, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71980594, Length=132, Percent_Identity=40.9090909090909, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71980590, Length=132, Percent_Identity=40.9090909090909, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17539498, Length=140, Percent_Identity=40, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17532641, Length=132, Percent_Identity=37.1212121212121, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17552780, Length=169, Percent_Identity=35.5029585798817, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71997782, Length=123, Percent_Identity=38.2113821138211, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17566266, Length=142, Percent_Identity=34.5070422535211, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559074, Length=140, Percent_Identity=34.2857142857143, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565860, Length=144, Percent_Identity=38.8888888888889, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17552782, Length=151, Percent_Identity=33.112582781457, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17506307, Length=150, Percent_Identity=35.3333333333333, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321848, Length=182, Percent_Identity=36.8131868131868, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320359, Length=162, Percent_Identity=35.8024691358025, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323562, Length=130, Percent_Identity=38.4615384615385, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320510, Length=172, Percent_Identity=34.8837209302326, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17986117, Length=164, Percent_Identity=37.8048780487805, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45549139, Length=134, Percent_Identity=44.7761194029851, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24652460, Length=133, Percent_Identity=39.0977443609023, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19922376, Length=149, Percent_Identity=32.8859060402685, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24664125, Length=140, Percent_Identity=41.4285714285714, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357783, Length=140, Percent_Identity=41.4285714285714, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17136360, Length=142, Percent_Identity=35.9154929577465, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922912, Length=163, Percent_Identity=39.8773006134969, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17647301, Length=133, Percent_Identity=38.3458646616541, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357249, Length=121, Percent_Identity=38.8429752066116, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24661775, Length=162, Percent_Identity=31.4814814814815, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355237, Length=162, Percent_Identity=31.4814814814815, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24661771, Length=162, Percent_Identity=31.4814814814815, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20130249, Length=127, Percent_Identity=37.7952755905512, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24650807, Length=137, Percent_Identity=35.036496350365, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21044; Mature: 20913

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSNIFQRRMFCLLLAALPVLGMAGEMASAAKAAAPDPYHTVYLDTKDGRITIALRPDL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCC
APKTVAQIETLTRRGFYDGIVFHRVIDGFMAQTGDPTGTGTGKSDLPNVPAEFTSTPFKR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
GTVGMARAQDPNSGNSQFFITFADADFLNNQYTVVGQVVSGMDVVDKIKKGSSSNNGSVS
CCCCCCCCCCCCCCCCEEEEEEECCHHCCCCEEEEHHHHCCHHHHHHHHCCCCCCCCCCC
NPDKIIKMRMADQEK
CHHHHEEECCCCCCC
>Mature Secondary Structure 
SKSNIFQRRMFCLLLAALPVLGMAGEMASAAKAAAPDPYHTVYLDTKDGRITIALRPDL
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCC
APKTVAQIETLTRRGFYDGIVFHRVIDGFMAQTGDPTGTGTGKSDLPNVPAEFTSTPFKR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
GTVGMARAQDPNSGNSQFFITFADADFLNNQYTVVGQVVSGMDVVDKIKKGSSSNNGSVS
CCCCCCCCCCCCCCCCEEEEEEECCHHCCCCEEEEHHHHCCHHHHHHHHCCCCCCCCCCC
NPDKIIKMRMADQEK
CHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA