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The map label for this gene is coaD

Identifier: 182679300

GI number: 182679300

Start: 2680826

End: 2681329

Strand: Reverse

Name: coaD

Synonym: Bind_2344

Alternate gene names: 182679300

Gene position: 2681329-2680826 (Counterclockwise)

Preceding gene: 182679301

Following gene: 182679299

Centisome position: 64.3

GC content: 60.12

Gene sequence:

>504_bases
ATGAGTCTCGTGGCGCTCTATACGGGATCATTCGATCCGCTAACACTTGGTCATATGGATGTCATTGGCAATGCGGCGGT
GCTTTGTGACGAAGTGATTGTCGCCATTGGTGTCAATCCGAGCAAGACGCCGTTGTTCACCGCGCAGGAGCGTATCACCC
TGATCGAATCCGCCTGCGGACCGCTGTTTGCCAGCCATGCCTGCAAGCTTTCGGTGCGCCTGTTCTCGGGGCTCGCGGTC
GAGGCGGCGCGGGAGGCTGGTGCCCAACTCCTGGTGCGGGGCCTGCGCGATGGCAGCGATCTCGATTTTGAAATGCAAAT
GGCATCGATGAATCGTGTCATGGCTCCGGATATTCAGACCATCTTCTTCCCCGCGGCACCCGCCGTGCGTCATATTACGG
CGACCTTGGTCCGCCAGGTTGCGACTATGGGCGGCGATGCCTCGCCCTTTGTACCCCCCGTCGTCGCGGCGGCGCTTGCT
CAGAAAACCAGCCTTCCATCGTGA

Upstream 100 bases:

>100_bases
CCAATATACAACCTCCTCATCGAGCCTCCAGAAAAAGCTCGGTGTCAATTGAGGCCGTCCGTCTGGCCTTGTCGTGCCGT
GATAGCAGTGAGTATGTCGT

Downstream 100 bases:

>100_bases
AACTGCCGAGGAGATCTTCAGGTCAATGTCAAAATCCAACATTTTTCAACGACGGATGTTTTGTCTTCTGCTCGCCGCTT
TGCCCGTCCTCGGCATGGCT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSLVALYTGSFDPLTLGHMDVIGNAAVLCDEVIVAIGVNPSKTPLFTAQERITLIESACGPLFASHACKLSVRLFSGLAV
EAAREAGAQLLVRGLRDGSDLDFEMQMASMNRVMAPDIQTIFFPAAPAVRHITATLVRQVATMGGDASPFVPPVVAAALA
QKTSLPS

Sequences:

>Translated_167_residues
MSLVALYTGSFDPLTLGHMDVIGNAAVLCDEVIVAIGVNPSKTPLFTAQERITLIESACGPLFASHACKLSVRLFSGLAV
EAAREAGAQLLVRGLRDGSDLDFEMQMASMNRVMAPDIQTIFFPAAPAVRHITATLVRQVATMGGDASPFVPPVVAAALA
QKTSLPS
>Mature_166_residues
SLVALYTGSFDPLTLGHMDVIGNAAVLCDEVIVAIGVNPSKTPLFTAQERITLIESACGPLFASHACKLSVRLFSGLAVE
AAREAGAQLLVRGLRDGSDLDFEMQMASMNRVMAPDIQTIFFPAAPAVRHITATLVRQVATMGGDASPFVPPVVAAALAQ
KTSLPS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=162, Percent_Identity=38.8888888888889, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_BEII9 (B2IHR4)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001833446.1
- ProteinModelPortal:   B2IHR4
- GeneID:   6199264
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_2344
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17496; Mature: 17364

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVALYTGSFDPLTLGHMDVIGNAAVLCDEVIVAIGVNPSKTPLFTAQERITLIESACG
CCEEEEEECCCCCEECCHHHHHCCHHHHHHHHHHEECCCCCCCCEEEHHHHHHHHHHHHH
PLFASHACKLSVRLFSGLAVEAAREAGAQLLVRGLRDGSDLDFEMQMASMNRVMAPDIQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCCCCCCCE
IFFPAAPAVRHITATLVRQVATMGGDASPFVPPVVAAALAQKTSLPS
EEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLVALYTGSFDPLTLGHMDVIGNAAVLCDEVIVAIGVNPSKTPLFTAQERITLIESACG
CEEEEEECCCCCEECCHHHHHCCHHHHHHHHHHEECCCCCCCCEEEHHHHHHHHHHHHH
PLFASHACKLSVRLFSGLAVEAAREAGAQLLVRGLRDGSDLDFEMQMASMNRVMAPDIQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCCCCCCCE
IFFPAAPAVRHITATLVRQVATMGGDASPFVPPVVAAALAQKTSLPS
EEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA