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The map label for this gene is fecD [C]

Identifier: 182679285

GI number: 182679285

Start: 2666496

End: 2667542

Strand: Reverse

Name: fecD [C]

Synonym: Bind_2329

Alternate gene names: 182679285

Gene position: 2667542-2666496 (Counterclockwise)

Preceding gene: 182679286

Following gene: 182679284

Centisome position: 63.97

GC content: 61.13

Gene sequence:

>1047_bases
ATGTCGACACTATCCTACACTGATGTTCCGGCGCGCCGGGAGAGGACCTGGCACGCGCCCCTGCTCGTGATTTTGCTCGG
CCTCACGATCGCCATAGCGCTCACCATCGGCCGCTATCCCTTGAGCCTGTCCGATCTCCTGGACTTCTCTCTCGCCTCCT
TGCGCGTGAAGACGATCGCGGCGACGCGCTATGATCTTCTCTATAATGTCATCGTCGAAATCAGATTGCCGCGTGTGCTT
GCCGCCGGCCTCATCGGCGCGGCTTTGTCGATCTCGGGCGGGGCCTATCAGGCGGTGTTTCGCAATCCGCTTGTCTCTCC
CGGGATCATGGGTGTGCTGGCCGGGGCGAGTTTCGGCGCGGCCCTTGGCATGCTGGTCGCCAGCCAATGGTTTTTGGTGC
AGGTCCTGGCCTTTGCCTTCGGCCTCGGCGCGGTGGCGCTCGGCGTCATCATCGCCAATTTGTTCGGTCCCGCGACGATG
ATCACTTTGATCCTCGGCGGTATGATCAGCGGGGCTTTCTTCACCGCCGCGCTGTCCATCGTTAAATATACGGCGGATCC
CTATGATCAATTGCCGGCCATCGTTTATTGGCTGATGGGCCATTTGGGCGGCATCGAACTGCGGGATGTCGGCGTGCTCA
CGCCTTTCGTCCTGATCGGCTGCGCCATCCTTTCGATGTTCGGCCGAGGTCTCGATGCTCTCGCCATGGGTGAGGACGAG
GCCCGCTCGCTTGGCGTACCCGTCTTTGTCCTGCGTTATGGCGTCATTGCGGTGGCGACCTTCGTTTCCTCCATTTCGGT
TTCATTCGCGGGGATGATTGGCTGGATCGGTCTCGTCGTGCCGCATTTCGCGCGGGTCGTCGTCGGCCCCGGCAATGCGC
GGCTGCTGCCGGCCAGCGCGTGCATGGGCGCGATCTTTTTGATCATCGCCGATGGTTTCGCGCGTAATCTCTGGCGGGCT
GAAATCCCCGTCGGCATCATGACAGAATTGTTCGGCATTCCGGCTTTTCTGCTCGTGATCTATCGGGCGCGGAAAGGCTG
GGCATGA

Upstream 100 bases:

>100_bases
CTTGCCGCCAATTTCTATCCTGACCGCTTTTCTTTCGATCTTCGCGCCGAGCTGAAAACCTTCCATAGCTTATTCTTCGG
CGTCAGCCTCAGCGATAAAG

Downstream 100 bases:

>100_bases
ATTGCGATCCGGACAGCCTGCTCAGAGCCGAGGGTTTGACCTTCGATCGCCAGGGCCGGGCGATTTTGCGCGGCGTTGAT
CTCACAATCGGCCCAGGCGA

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSTLSYTDVPARRERTWHAPLLVILLGLTIAIALTIGRYPLSLSDLLDFSLASLRVKTIAATRYDLLYNVIVEIRLPRVL
AAGLIGAALSISGGAYQAVFRNPLVSPGIMGVLAGASFGAALGMLVASQWFLVQVLAFAFGLGAVALGVIIANLFGPATM
ITLILGGMISGAFFTAALSIVKYTADPYDQLPAIVYWLMGHLGGIELRDVGVLTPFVLIGCAILSMFGRGLDALAMGEDE
ARSLGVPVFVLRYGVIAVATFVSSISVSFAGMIGWIGLVVPHFARVVVGPGNARLLPASACMGAIFLIIADGFARNLWRA
EIPVGIMTELFGIPAFLLVIYRARKGWA

Sequences:

>Translated_348_residues
MSTLSYTDVPARRERTWHAPLLVILLGLTIAIALTIGRYPLSLSDLLDFSLASLRVKTIAATRYDLLYNVIVEIRLPRVL
AAGLIGAALSISGGAYQAVFRNPLVSPGIMGVLAGASFGAALGMLVASQWFLVQVLAFAFGLGAVALGVIIANLFGPATM
ITLILGGMISGAFFTAALSIVKYTADPYDQLPAIVYWLMGHLGGIELRDVGVLTPFVLIGCAILSMFGRGLDALAMGEDE
ARSLGVPVFVLRYGVIAVATFVSSISVSFAGMIGWIGLVVPHFARVVVGPGNARLLPASACMGAIFLIIADGFARNLWRA
EIPVGIMTELFGIPAFLLVIYRARKGWA
>Mature_347_residues
STLSYTDVPARRERTWHAPLLVILLGLTIAIALTIGRYPLSLSDLLDFSLASLRVKTIAATRYDLLYNVIVEIRLPRVLA
AGLIGAALSISGGAYQAVFRNPLVSPGIMGVLAGASFGAALGMLVASQWFLVQVLAFAFGLGAVALGVIIANLFGPATMI
TLILGGMISGAFFTAALSIVKYTADPYDQLPAIVYWLMGHLGGIELRDVGVLTPFVLIGCAILSMFGRGLDALAMGEDEA
RSLGVPVFVLRYGVIAVATFVSSISVSFAGMIGWIGLVVPHFARVVVGPGNARLLPASACMGAIFLIIADGFARNLWRAE
IPVGIMTELFGIPAFLLVIYRARKGWA

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=36.4285714285714, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788004, Length=282, Percent_Identity=36.1702127659575, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786805, Length=303, Percent_Identity=31.3531353135314, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1790741, Length=278, Percent_Identity=31.294964028777, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786347, Length=285, Percent_Identity=28.0701754385965, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786804, Length=277, Percent_Identity=31.4079422382672, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36771; Mature: 36640

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLSYTDVPARRERTWHAPLLVILLGLTIAIALTIGRYPLSLSDLLDFSLASLRVKTIA
CCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ATRYDLLYNVIVEIRLPRVLAAGLIGAALSISGGAYQAVFRNPLVSPGIMGVLAGASFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
ALGMLVASQWFLVQVLAFAFGLGAVALGVIIANLFGPATMITLILGGMISGAFFTAALSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKYTADPYDQLPAIVYWLMGHLGGIELRDVGVLTPFVLIGCAILSMFGRGLDALAMGEDE
HHHCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHH
ARSLGVPVFVLRYGVIAVATFVSSISVSFAGMIGWIGLVVPHFARVVVGPGNARLLPASA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEHHH
CMGAIFLIIADGFARNLWRAEIPVGIMTELFGIPAFLLVIYRARKGWA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STLSYTDVPARRERTWHAPLLVILLGLTIAIALTIGRYPLSLSDLLDFSLASLRVKTIA
CCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ATRYDLLYNVIVEIRLPRVLAAGLIGAALSISGGAYQAVFRNPLVSPGIMGVLAGASFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
ALGMLVASQWFLVQVLAFAFGLGAVALGVIIANLFGPATMITLILGGMISGAFFTAALSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKYTADPYDQLPAIVYWLMGHLGGIELRDVGVLTPFVLIGCAILSMFGRGLDALAMGEDE
HHHCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHH
ARSLGVPVFVLRYGVIAVATFVSSISVSFAGMIGWIGLVVPHFARVVVGPGNARLLPASA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEHHH
CMGAIFLIIADGFARNLWRAEIPVGIMTELFGIPAFLLVIYRARKGWA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]