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The map label for this gene is acoR [H]

Identifier: 182679179

GI number: 182679179

Start: 2542961

End: 2544916

Strand: Reverse

Name: acoR [H]

Synonym: Bind_2218

Alternate gene names: 182679179

Gene position: 2544916-2542961 (Counterclockwise)

Preceding gene: 182679180

Following gene: 182679178

Centisome position: 61.03

GC content: 59.71

Gene sequence:

>1956_bases
ATGGCTGCGAGCCCGGCAATATTGTCCGCACGAAGAGCGGAGGGCGATCATATCGAGGAAATCGAGCGCGTCCTCTCCGG
CGCGGTCTCGACGCGTGATAGCACGGTCGTGCGCTCCTGGTTGCGCTGTGTGGATGAGCATAAGCTCGATCCCGCCCGGC
CGACGGAAGCCTATATCGTGCCGGAGACGCAATTGCGGGAGCATCGGGAGCAGTCGGAGCGCCTGATCGGCATTGCGCGG
ACCGGGCTCGAACATCTTTATCGTCAGGTGGCGGGCCAGAATTATGTGCTGCTGTTGGCCGATGCCCAGGGTGTAACCGT
CGATTTTCTCGGCGATCCGGCATTTATGGACCCTTTGCGTGAGGCGGGTCTCATGCTCGGTTCGGAATGGTCGGAGGCAC
GGACCGGAACCTGCGGCGTTGGTTCCTGCATCGTTGCCGGCGAGGCGATGACGATCCATCAAAGCGATCATTTCGACACG
ACGCATACAAGGCTGAGTTGTACCGCCGCGCCGATCTTCGACACGAATGGCGCCCTCACGGCTGTTCTCGATATTTCACT
CTTGCGTTCGCCTCAACCCAAGGTGAGTCAAACTCTGGCTTTGCATCTGGTGACGGCGTCCGCGCGCCGTATTGAACTCG
CCAATCTGATGGCGCGGATGCGCTCCAACTGGGTGCTGCGTTTTTCCCGCTCGCCGGATTTTCTCGATGTTGATCCAGAA
GCCGCCATTGCGCTCGACGGGTCGGGCCGTATTCTTGGCATGACGCATGGGGGCGCCATCTTGTTGGCGGGCGTCGCGGG
GCTCGATTGGCGTGAAGCTGCCGGTATTATCGGCCAGCCTTTATCCTGTTTCTTCGATATGAGCGTTGATGACCTTCCAG
CTTTTACCCGTGGCCGGGCGGCGGAGGAACGGATCCTCTTTGCCCGCGACGCCAGCGCGGTCTTTGTTCATGCCATCGAA
CCGGAGCGCCATCCCGCCAGCAAGCGGATGCCTGCTCCCATTCTGCCTCAATCCTTGCGGGGCCTGAGTGGAGGCGACAG
TCAAATGGATGCCCTGCAAGCCAAGGCCGCCAAACTGGCCGGGACCGACATCCCCATTCTCCTCCAGGGCGAGACGGGGA
CAGGCAAGGAATATCTGGCGAGGGCCATTCATGAATGCCGTCCGGGCAATGGATCTTTCATTGCCGTGAATTGCGCTTCG
ATCCCGGAACAACTCATCGAAAGCGAATTGTTCGGATATGGGCCAGGGGCTTTCACTGGCGCCCTGGCGCGGGGAAAAAG
GGGCCTGATCGAGGAAGCGGATGGGGGCACATTATTTCTTGATGAAATCGGCGATATGCCGCTGGCCTTGCAGGCCCGTC
TGTTGCGCGTCCTGGCCGAACGGGAAGTGACACCCCTTGGACAATCGAAGCCGAAGACGGTTCGAATTAAAATCATTTCC
GCATCGCATCGTGACCTCGGCCAACTCGTCGAGGAAGGGCGCTTTCGTGAGGATCTGTACTATCGCTTGAATGCCGCCGT
TCTGACCTTGCCGGCGCTGCAGCAAAGAGAGGATTTCGATTGGCTCCTCGATCGTCTGATCCACCAGCGGGCCAGTGCGC
AGAACAAACAGATACGGCTTGCTCCCGATGCGCGGTTGGCGCTCTCCCGCCACGGCTGGCCGGGCAATCTCCGCGAATTG
GTGAATGTGATCGATGTCGCCCTTTCTCTCAACGAGGATGGTGTGATCACTGGCCAGGATCTGCCGGCATTGGCTCGAAC
GCCACCATCGCGTGAGACGCTAAATCAGCAAATTCCGTTTGAGGCAAAGCGATCCAAGAGTGCGCGTGCAAAGCTCGAAA
CGGCTTTGGCGGAATGCCAAGGCAATCTGTCTGAAGTTGCCCGCCGCCTCGATATCGACCGGACGACCGTCTATCGGCGC
ATCAAACGCCTCGGCCTTGTCATCTCGCGCCCGTAG

Upstream 100 bases:

>100_bases
AGCTTCCCGCGAGCCCGCTATTCTGCGCCCAAGCGTCGGCCTTTGCTCCTTGTGAGAAAAGAGAGAAGGGCGCAACGAGG
GAACAGGGAGGAAGTCAGAA

Downstream 100 bases:

>100_bases
AACGCCACATGTGGCATTTGCAATAGAGAGCGCTGTGGCAGATGCCACGGCAGGGGTTCGGCTCAAATAATAAAGATGAG
TATTTTCAATAAAATAACAA

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MAASPAILSARRAEGDHIEEIERVLSGAVSTRDSTVVRSWLRCVDEHKLDPARPTEAYIVPETQLREHREQSERLIGIAR
TGLEHLYRQVAGQNYVLLLADAQGVTVDFLGDPAFMDPLREAGLMLGSEWSEARTGTCGVGSCIVAGEAMTIHQSDHFDT
THTRLSCTAAPIFDTNGALTAVLDISLLRSPQPKVSQTLALHLVTASARRIELANLMARMRSNWVLRFSRSPDFLDVDPE
AAIALDGSGRILGMTHGGAILLAGVAGLDWREAAGIIGQPLSCFFDMSVDDLPAFTRGRAAEERILFARDASAVFVHAIE
PERHPASKRMPAPILPQSLRGLSGGDSQMDALQAKAAKLAGTDIPILLQGETGTGKEYLARAIHECRPGNGSFIAVNCAS
IPEQLIESELFGYGPGAFTGALARGKRGLIEEADGGTLFLDEIGDMPLALQARLLRVLAEREVTPLGQSKPKTVRIKIIS
ASHRDLGQLVEEGRFREDLYYRLNAAVLTLPALQQREDFDWLLDRLIHQRASAQNKQIRLAPDARLALSRHGWPGNLREL
VNVIDVALSLNEDGVITGQDLPALARTPPSRETLNQQIPFEAKRSKSARAKLETALAECQGNLSEVARRLDIDRTTVYRR
IKRLGLVISRP

Sequences:

>Translated_651_residues
MAASPAILSARRAEGDHIEEIERVLSGAVSTRDSTVVRSWLRCVDEHKLDPARPTEAYIVPETQLREHREQSERLIGIAR
TGLEHLYRQVAGQNYVLLLADAQGVTVDFLGDPAFMDPLREAGLMLGSEWSEARTGTCGVGSCIVAGEAMTIHQSDHFDT
THTRLSCTAAPIFDTNGALTAVLDISLLRSPQPKVSQTLALHLVTASARRIELANLMARMRSNWVLRFSRSPDFLDVDPE
AAIALDGSGRILGMTHGGAILLAGVAGLDWREAAGIIGQPLSCFFDMSVDDLPAFTRGRAAEERILFARDASAVFVHAIE
PERHPASKRMPAPILPQSLRGLSGGDSQMDALQAKAAKLAGTDIPILLQGETGTGKEYLARAIHECRPGNGSFIAVNCAS
IPEQLIESELFGYGPGAFTGALARGKRGLIEEADGGTLFLDEIGDMPLALQARLLRVLAEREVTPLGQSKPKTVRIKIIS
ASHRDLGQLVEEGRFREDLYYRLNAAVLTLPALQQREDFDWLLDRLIHQRASAQNKQIRLAPDARLALSRHGWPGNLREL
VNVIDVALSLNEDGVITGQDLPALARTPPSRETLNQQIPFEAKRSKSARAKLETALAECQGNLSEVARRLDIDRTTVYRR
IKRLGLVISRP
>Mature_650_residues
AASPAILSARRAEGDHIEEIERVLSGAVSTRDSTVVRSWLRCVDEHKLDPARPTEAYIVPETQLREHREQSERLIGIART
GLEHLYRQVAGQNYVLLLADAQGVTVDFLGDPAFMDPLREAGLMLGSEWSEARTGTCGVGSCIVAGEAMTIHQSDHFDTT
HTRLSCTAAPIFDTNGALTAVLDISLLRSPQPKVSQTLALHLVTASARRIELANLMARMRSNWVLRFSRSPDFLDVDPEA
AIALDGSGRILGMTHGGAILLAGVAGLDWREAAGIIGQPLSCFFDMSVDDLPAFTRGRAAEERILFARDASAVFVHAIEP
ERHPASKRMPAPILPQSLRGLSGGDSQMDALQAKAAKLAGTDIPILLQGETGTGKEYLARAIHECRPGNGSFIAVNCASI
PEQLIESELFGYGPGAFTGALARGKRGLIEEADGGTLFLDEIGDMPLALQARLLRVLAEREVTPLGQSKPKTVRIKIISA
SHRDLGQLVEEGRFREDLYYRLNAAVLTLPALQQREDFDWLLDRLIHQRASAQNKQIRLAPDARLALSRHGWPGNLRELV
NVIDVALSLNEDGVITGQDLPALARTPPSRETLNQQIPFEAKRSKSARAKLETALAECQGNLSEVARRLDIDRTTVYRRI
KRLGLVISRP

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=348, Percent_Identity=41.3793103448276, Blast_Score=229, Evalue=5e-61,
Organism=Escherichia coli, GI1788905, Length=296, Percent_Identity=43.9189189189189, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1788550, Length=314, Percent_Identity=42.0382165605096, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI87082117, Length=331, Percent_Identity=42.5981873111783, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1790437, Length=325, Percent_Identity=39.3846153846154, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1790299, Length=314, Percent_Identity=41.7197452229299, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1786524, Length=316, Percent_Identity=39.5569620253165, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1789087, Length=309, Percent_Identity=39.1585760517799, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI87082152, Length=320, Percent_Identity=37.1875, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1787583, Length=304, Percent_Identity=35.5263157894737, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=41.1255411255411, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1789828, Length=224, Percent_Identity=40.625, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI87081858, Length=634, Percent_Identity=24.4479495268139, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 71066; Mature: 70935

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASPAILSARRAEGDHIEEIERVLSGAVSTRDSTVVRSWLRCVDEHKLDPARPTEAYIV
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEC
PETQLREHREQSERLIGIARTGLEHLYRQVAGQNYVLLLADAQGVTVDFLGDPAFMDPLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCHHHHHHH
EAGLMLGSEWSEARTGTCGVGSCIVAGEAMTIHQSDHFDTTHTRLSCTAAPIFDTNGALT
HHHHHCCCCHHHCCCCCCCCCCEEEECCEEEEECCCCCCCCCCEEEEEECCEECCCCCEE
AVLDISLLRSPQPKVSQTLALHLVTASARRIELANLMARMRSNWVLRFSRSPDFLDVDPE
EEEEHHHHCCCCCHHHHHHHHHEEHHCHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCC
AAIALDGSGRILGMTHGGAILLAGVAGLDWREAAGIIGQPLSCFFDMSVDDLPAFTRGRA
CEEEECCCCCEEEEECCCEEEEEECCCCCHHHHCCCCCCCCHHEECCCHHHCCCHHCCCC
AEERILFARDASAVFVHAIEPERHPASKRMPAPILPQSLRGLSGGDSQMDALQAKAAKLA
HHHHEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHC
GTDIPILLQGETGTGKEYLARAIHECRPGNGSFIAVNCASIPEQLIESELFGYGPGAFTG
CCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHH
ALARGKRGLIEEADGGTLFLDEIGDMPLALQARLLRVLAEREVTPLGQSKPKTVRIKIIS
HHHCCCCCCCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEE
ASHRDLGQLVEEGRFREDLYYRLNAAVLTLPALQQREDFDWLLDRLIHQRASAQNKQIRL
CCCHHHHHHHHCCCCHHHHHHHHHHHEEECCCHHCCCCHHHHHHHHHHHHHCCCCCEEEE
APDARLALSRHGWPGNLRELVNVIDVALSLNEDGVITGQDLPALARTPPSRETLNQQIPF
CCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHCCCCCHHHHCCCCCC
EAKRSKSARAKLETALAECQGNLSEVARRLDIDRTTVYRRIKRLGLVISRP
HHHHCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCEECCC
>Mature Secondary Structure 
AASPAILSARRAEGDHIEEIERVLSGAVSTRDSTVVRSWLRCVDEHKLDPARPTEAYIV
CCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEC
PETQLREHREQSERLIGIARTGLEHLYRQVAGQNYVLLLADAQGVTVDFLGDPAFMDPLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCHHHHHHH
EAGLMLGSEWSEARTGTCGVGSCIVAGEAMTIHQSDHFDTTHTRLSCTAAPIFDTNGALT
HHHHHCCCCHHHCCCCCCCCCCEEEECCEEEEECCCCCCCCCCEEEEEECCEECCCCCEE
AVLDISLLRSPQPKVSQTLALHLVTASARRIELANLMARMRSNWVLRFSRSPDFLDVDPE
EEEEHHHHCCCCCHHHHHHHHHEEHHCHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCC
AAIALDGSGRILGMTHGGAILLAGVAGLDWREAAGIIGQPLSCFFDMSVDDLPAFTRGRA
CEEEECCCCCEEEEECCCEEEEEECCCCCHHHHCCCCCCCCHHEECCCHHHCCCHHCCCC
AEERILFARDASAVFVHAIEPERHPASKRMPAPILPQSLRGLSGGDSQMDALQAKAAKLA
HHHHEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHC
GTDIPILLQGETGTGKEYLARAIHECRPGNGSFIAVNCASIPEQLIESELFGYGPGAFTG
CCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHH
ALARGKRGLIEEADGGTLFLDEIGDMPLALQARLLRVLAEREVTPLGQSKPKTVRIKIIS
HHHCCCCCCCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEE
ASHRDLGQLVEEGRFREDLYYRLNAAVLTLPALQQREDFDWLLDRLIHQRASAQNKQIRL
CCCHHHHHHHHCCCCHHHHHHHHHHHEEECCCHHCCCCHHHHHHHHHHHHHCCCCCEEEE
APDARLALSRHGWPGNLRELVNVIDVALSLNEDGVITGQDLPALARTPPSRETLNQQIPF
CCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHCCCCCHHHHCCCCCC
EAKRSKSARAKLETALAECQGNLSEVARRLDIDRTTVYRRIKRLGLVISRP
HHHHCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]