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The map label for this gene is yfdE [H]

Identifier: 182679173

GI number: 182679173

Start: 2535838

End: 2537118

Strand: Direct

Name: yfdE [H]

Synonym: Bind_2211

Alternate gene names: 182679173

Gene position: 2535838-2537118 (Clockwise)

Preceding gene: 182679169

Following gene: 182679174

Centisome position: 60.81

GC content: 58.16

Gene sequence:

>1281_bases
ATGGAACATGCATCCCAGGCCCAAGATACGGAGGGCGCCAGCATGGACACAATCGAAGAACCCGATTCCCCGCCCGCTGA
TACAAGGCCACTGCCGCTCGCGGGGATCAGGGTTCTCGATGTCACGCAGGTCATGGCCGGACCCTTCTGCACCATGCTGC
TCGCCGATCTGGGCGCCGATGTTATCAAGATCGAACCACCCGAGACGGGTGATCAGACGCGTGGCGCCATGGGCTTCAAG
CTCAAGGGCAATGACAGTATGGGGTTCTTGAATCTCAATCGGAACAAGAGAAGCCTGACGCTCAATCTCAAAAATCCGGC
TGGAAAAGCGACCTTCCTCAAACTGGTGGAAAAGGCCGATATTGTCGTCGAAAATTACCGGCCCGGCGTCGTGAAGAAAC
TTGATATCGATTACGAGACTCTTTCGGCAATCAATCCCCGCCTCGTCTATGCAAGCATTTCCGGCTTCGGACAGAGTGGG
CCCTGGGCGGATCGCCCCGGCTTTGATTTGATGGCGCAGGCCATGTCCGGCGTCATGAGTGTCACCGGCCATCCGGGTGG
CCCGCCCGTGAAGGCCGGCGTCCCCGTCGCCGATATCGGCTGCGCCCTCTTTGCGACCTATGCGATCCTCGCTGCCTATA
TCGGCTGCAAATCCACGGGACGCGGACAATTCATCGATGCCTCGCTGTTCGAGGCGGCCATGGCCTTTTCCATTTGGGAC
ATTTCAGAATATTGGGGCACCGGCCGCGTGCCGGAGCCGCTCGGCACAGCCAACCGCATGAGCGCGCCCTATCAAGCCGT
GAAGGCAGCGGACGGCTATTTCGTCATGGGCGCGACGAACCAGAAACTCTGGCGTCTGCTCTGTCAGGAACTGGGCCGTG
AAGACCTGCTCGATGATCCACGCTACACGGATATTCCGTCACGTCTCGCCAATCGGGACATTCTCATCACGGAACTCGAA
AAGACATTCATCACCCGATCAAGAGACGAATGGGTGAAGCGCCTGCTCGACATCGGAATACCGGCGGGGCATATGCACAC
TTACCCGCAAGCCTTTGAAAGCGAACACGGCCGCCATCGTCAGATGCGTCTCGAGATTGATCATCCTGTCGAAGGCAAAG
TGCCCAATATCGGTTTTCCGGTCAAACTGACGGGAACACCGCAACAGATTCGCATGCATCCGCCGCTGCTCGGCGAGCAT
ACGGATGAAGTGCTCGTCGAGCTCGGTCTCGAGCCGGAGAGCTTGGAAGAATTACGCGCTCAGGGAGCCTTCTCACTATG
A

Upstream 100 bases:

>100_bases
CATTATACGAATGGCAGTTTGCCAAGAGCCATTCAATCAATTATGAATAATGAATTCATTTTTTGGACTAAAACAAAAGA
CGAGGAAGGAGGCTATCTTC

Downstream 100 bases:

>100_bases
ATGCGCCGATTGCCAACCCGGGACGCGTGACCCTCAATGTCGAGGGTGCGATCGCTTATATTGTGTTCGATCATCAATCC
GCCCGCAATGCGATGACCTG

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MEHASQAQDTEGASMDTIEEPDSPPADTRPLPLAGIRVLDVTQVMAGPFCTMLLADLGADVIKIEPPETGDQTRGAMGFK
LKGNDSMGFLNLNRNKRSLTLNLKNPAGKATFLKLVEKADIVVENYRPGVVKKLDIDYETLSAINPRLVYASISGFGQSG
PWADRPGFDLMAQAMSGVMSVTGHPGGPPVKAGVPVADIGCALFATYAILAAYIGCKSTGRGQFIDASLFEAAMAFSIWD
ISEYWGTGRVPEPLGTANRMSAPYQAVKAADGYFVMGATNQKLWRLLCQELGREDLLDDPRYTDIPSRLANRDILITELE
KTFITRSRDEWVKRLLDIGIPAGHMHTYPQAFESEHGRHRQMRLEIDHPVEGKVPNIGFPVKLTGTPQQIRMHPPLLGEH
TDEVLVELGLEPESLEELRAQGAFSL

Sequences:

>Translated_426_residues
MEHASQAQDTEGASMDTIEEPDSPPADTRPLPLAGIRVLDVTQVMAGPFCTMLLADLGADVIKIEPPETGDQTRGAMGFK
LKGNDSMGFLNLNRNKRSLTLNLKNPAGKATFLKLVEKADIVVENYRPGVVKKLDIDYETLSAINPRLVYASISGFGQSG
PWADRPGFDLMAQAMSGVMSVTGHPGGPPVKAGVPVADIGCALFATYAILAAYIGCKSTGRGQFIDASLFEAAMAFSIWD
ISEYWGTGRVPEPLGTANRMSAPYQAVKAADGYFVMGATNQKLWRLLCQELGREDLLDDPRYTDIPSRLANRDILITELE
KTFITRSRDEWVKRLLDIGIPAGHMHTYPQAFESEHGRHRQMRLEIDHPVEGKVPNIGFPVKLTGTPQQIRMHPPLLGEH
TDEVLVELGLEPESLEELRAQGAFSL
>Mature_426_residues
MEHASQAQDTEGASMDTIEEPDSPPADTRPLPLAGIRVLDVTQVMAGPFCTMLLADLGADVIKIEPPETGDQTRGAMGFK
LKGNDSMGFLNLNRNKRSLTLNLKNPAGKATFLKLVEKADIVVENYRPGVVKKLDIDYETLSAINPRLVYASISGFGQSG
PWADRPGFDLMAQAMSGVMSVTGHPGGPPVKAGVPVADIGCALFATYAILAAYIGCKSTGRGQFIDASLFEAAMAFSIWD
ISEYWGTGRVPEPLGTANRMSAPYQAVKAADGYFVMGATNQKLWRLLCQELGREDLLDDPRYTDIPSRLANRDILITELE
KTFITRSRDEWVKRLLDIGIPAGHMHTYPQAFESEHGRHRQMRLEIDHPVEGKVPNIGFPVKLTGTPQQIRMHPPLLGEH
TDEVLVELGLEPESLEELRAQGAFSL

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=392, Percent_Identity=36.734693877551, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI300863124, Length=418, Percent_Identity=34.9282296650718, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI300863126, Length=393, Percent_Identity=33.587786259542, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI13376042, Length=418, Percent_Identity=32.0574162679426, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI42794625, Length=400, Percent_Identity=29, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI266456254, Length=400, Percent_Identity=29, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI266458393, Length=275, Percent_Identity=34.5454545454545, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI266458397, Length=267, Percent_Identity=34.0823970037453, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI266458395, Length=148, Percent_Identity=39.1891891891892, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI42822893, Length=148, Percent_Identity=39.1891891891892, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI87082093, Length=355, Percent_Identity=36.3380281690141, Blast_Score=251, Evalue=4e-68,
Organism=Escherichia coli, GI1788717, Length=415, Percent_Identity=30.8433734939759, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1786222, Length=411, Percent_Identity=29.1970802919708, Blast_Score=108, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32564160, Length=306, Percent_Identity=27.7777777777778, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115535051, Length=307, Percent_Identity=27.6872964169381, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24648431, Length=390, Percent_Identity=38.4615384615385, Blast_Score=274, Evalue=8e-74,
Organism=Drosophila melanogaster, GI24585488, Length=402, Percent_Identity=29.3532338308458, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 46584; Mature: 46584

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHASQAQDTEGASMDTIEEPDSPPADTRPLPLAGIRVLDVTQVMAGPFCTMLLADLGAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
VIKIEPPETGDQTRGAMGFKLKGNDSMGFLNLNRNKRSLTLNLKNPAGKATFLKLVEKAD
EEEECCCCCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHH
IVVENYRPGVVKKLDIDYETLSAINPRLVYASISGFGQSGPWADRPGFDLMAQAMSGVMS
EEEECCCCCCEEEECCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEE
VTGHPGGPPVKAGVPVADIGCALFATYAILAAYIGCKSTGRGQFIDASLFEAAMAFSIWD
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHH
ISEYWGTGRVPEPLGTANRMSAPYQAVKAADGYFVMGATNQKLWRLLCQELGREDLLDDP
HHHHCCCCCCCCCCCCCHHCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHCCHHHCCCCC
RYTDIPSRLANRDILITELEKTFITRSRDEWVKRLLDIGIPAGHMHTYPQAFESEHGRHR
CCCCCHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCE
QMRLEIDHPVEGKVPNIGFPVKLTGTPQQIRMHPPLLGEHTDEVLVELGLEPESLEELRA
EEEEEECCCCCCCCCCCCCCEEECCCCHHEEECCCCCCCCHHHHHHHCCCCHHHHHHHHH
QGAFSL
CCCCCC
>Mature Secondary Structure
MEHASQAQDTEGASMDTIEEPDSPPADTRPLPLAGIRVLDVTQVMAGPFCTMLLADLGAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
VIKIEPPETGDQTRGAMGFKLKGNDSMGFLNLNRNKRSLTLNLKNPAGKATFLKLVEKAD
EEEECCCCCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHH
IVVENYRPGVVKKLDIDYETLSAINPRLVYASISGFGQSGPWADRPGFDLMAQAMSGVMS
EEEECCCCCCEEEECCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEE
VTGHPGGPPVKAGVPVADIGCALFATYAILAAYIGCKSTGRGQFIDASLFEAAMAFSIWD
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHH
ISEYWGTGRVPEPLGTANRMSAPYQAVKAADGYFVMGATNQKLWRLLCQELGREDLLDDP
HHHHCCCCCCCCCCCCCHHCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHCCHHHCCCCC
RYTDIPSRLANRDILITELEKTFITRSRDEWVKRLLDIGIPAGHMHTYPQAFESEHGRHR
CCCCCHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCE
QMRLEIDHPVEGKVPNIGFPVKLTGTPQQIRMHPPLLGEHTDEVLVELGLEPESLEELRA
EEEEEECCCCCCCCCCCCCCEEECCCCHHEEECCCCCCCCHHHHHHHCCCCHHHHHHHHH
QGAFSL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]