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The map label for this gene is crt [H]

Identifier: 182679174

GI number: 182679174

Start: 2537115

End: 2537903

Strand: Direct

Name: crt [H]

Synonym: Bind_2212

Alternate gene names: 182679174

Gene position: 2537115-2537903 (Clockwise)

Preceding gene: 182679173

Following gene: 182679176

Centisome position: 60.84

GC content: 59.57

Gene sequence:

>789_bases
ATGAATGCGCCGATTGCCAACCCGGGACGCGTGACCCTCAATGTCGAGGGTGCGATCGCTTATATTGTGTTCGATCATCA
ATCCGCCCGCAATGCGATGACCTGGGCGATGTATGATGACTTGGCCACGGCCTGCGCGGCGATCGATGCCGATCCAAGCA
TCCGTGTCGCCGTCTTGCGCGGCGCTGGCGGCAAGGCCTTTGTCGCCGGAACCGATATTGCGCAATTCCAGACGTTCACG
GGCGATGACGGCGTCGCCTATGAAGCCAAGGTCGATCGTTTTATCGCGACCTTGGAGAACCTTCGCGTGCCGACGATCGC
AGTCGTTGAAGGTTATGCGGTCGGCGGCGGTCTCGCCATCGCCAATGCCTGCGACATCCGTCTCTCCGCCACCGGAGCGC
GTTTCGGTGTACCCATCGCCCGGACATTGGGGAATTGTCTTTCCGCCGCGAATGTACGCCGGTTAGTCGCGGCTTTGGGA
ATATCCTGGGTCAAGCGGATGCTGCTGCTCGCCGAAATGCCCACGGCTGAGCAATTGGCCGCGATCGGCTATCTGGAAAC
AGTGGCGACGCCGGAACAACTTGATGGCGAAGTCACAAGACTCTGCAATCGTCTGTTGGAACACGCGCCCTTAACCATCA
AGGCGAGTCGAGAAACATTACGTCGCCTTGTACAGGCATCCGACCCTGATATCTCCGACCTGATCCATGCCTGCTACGGC
AGCGAGGATTTCCATCGCGCCGTAGCGGCTTTCGGCTCCAAGAACAAGACCGACTGGCAGGGGCGCTGA

Upstream 100 bases:

>100_bases
ATCCGCCGCTGCTCGGCGAGCATACGGATGAAGTGCTCGTCGAGCTCGGTCTCGAGCCGGAGAGCTTGGAAGAATTACGC
GCTCAGGGAGCCTTCTCACT

Downstream 100 bases:

>100_bases
TCCGATTCAGGCCACGCAAATATTGGCAACCGCGAGCTTGCGGAAAAGATGCGGCGAGGCGGTCGCGCTTGACGGATAGG
CTGCAAGCTTTGATTGGAAA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNAPIANPGRVTLNVEGAIAYIVFDHQSARNAMTWAMYDDLATACAAIDADPSIRVAVLRGAGGKAFVAGTDIAQFQTFT
GDDGVAYEAKVDRFIATLENLRVPTIAVVEGYAVGGGLAIANACDIRLSATGARFGVPIARTLGNCLSAANVRRLVAALG
ISWVKRMLLLAEMPTAEQLAAIGYLETVATPEQLDGEVTRLCNRLLEHAPLTIKASRETLRRLVQASDPDISDLIHACYG
SEDFHRAVAAFGSKNKTDWQGR

Sequences:

>Translated_262_residues
MNAPIANPGRVTLNVEGAIAYIVFDHQSARNAMTWAMYDDLATACAAIDADPSIRVAVLRGAGGKAFVAGTDIAQFQTFT
GDDGVAYEAKVDRFIATLENLRVPTIAVVEGYAVGGGLAIANACDIRLSATGARFGVPIARTLGNCLSAANVRRLVAALG
ISWVKRMLLLAEMPTAEQLAAIGYLETVATPEQLDGEVTRLCNRLLEHAPLTIKASRETLRRLVQASDPDISDLIHACYG
SEDFHRAVAAFGSKNKTDWQGR
>Mature_262_residues
MNAPIANPGRVTLNVEGAIAYIVFDHQSARNAMTWAMYDDLATACAAIDADPSIRVAVLRGAGGKAFVAGTDIAQFQTFT
GDDGVAYEAKVDRFIATLENLRVPTIAVVEGYAVGGGLAIANACDIRLSATGARFGVPIARTLGNCLSAANVRRLVAALG
ISWVKRMLLLAEMPTAEQLAAIGYLETVATPEQLDGEVTRLCNRLLEHAPLTIKASRETLRRLVQASDPDISDLIHACYG
SEDFHRAVAAFGSKNKTDWQGR

Specific function: Unknown

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI4502327, Length=251, Percent_Identity=23.9043824701195, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082183, Length=260, Percent_Identity=28.4615384615385, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787659, Length=249, Percent_Identity=30.1204819277108, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=29.5019157088123, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788597, Length=207, Percent_Identity=27.536231884058, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790281, Length=187, Percent_Identity=28.3422459893048, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=254, Percent_Identity=26.7716535433071, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25145438, Length=256, Percent_Identity=27.734375, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=210, Percent_Identity=24.2857142857143, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=219, Percent_Identity=25.5707762557078, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=24.6511627906977, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=215, Percent_Identity=26.046511627907, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535521, Length=250, Percent_Identity=23.6, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=28.1632653061224, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=28.1632653061224, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24653139, Length=251, Percent_Identity=23.5059760956175, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27917; Mature: 27917

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPIANPGRVTLNVEGAIAYIVFDHQSARNAMTWAMYDDLATACAAIDADPSIRVAVLR
CCCCCCCCCEEEEEECCEEEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEE
GAGGKAFVAGTDIAQFQTFTGDDGVAYEAKVDRFIATLENLRVPTIAVVEGYAVGGGLAI
CCCCEEEEECCCHHHEEEECCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECEEECCCEEE
ANACDIRLSATGARFGVPIARTLGNCLSAANVRRLVAALGISWVKRMLLLAEMPTAEQLA
ECEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AIGYLETVATPEQLDGEVTRLCNRLLEHAPLTIKASRETLRRLVQASDPDISDLIHACYG
HHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCCHHHHHHHHCC
SEDFHRAVAAFGSKNKTDWQGR
CHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNAPIANPGRVTLNVEGAIAYIVFDHQSARNAMTWAMYDDLATACAAIDADPSIRVAVLR
CCCCCCCCCEEEEEECCEEEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEE
GAGGKAFVAGTDIAQFQTFTGDDGVAYEAKVDRFIATLENLRVPTIAVVEGYAVGGGLAI
CCCCEEEEECCCHHHEEEECCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECEEECCCEEE
ANACDIRLSATGARFGVPIARTLGNCLSAANVRRLVAALGISWVKRMLLLAEMPTAEQLA
ECEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AIGYLETVATPEQLDGEVTRLCNRLLEHAPLTIKASRETLRRLVQASDPDISDLIHACYG
HHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCCHHHHHHHHCC
SEDFHRAVAAFGSKNKTDWQGR
CHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]