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The map label for this gene is gudP [H]

Identifier: 182679172

GI number: 182679172

Start: 2534245

End: 2535612

Strand: Reverse

Name: gudP [H]

Synonym: Bind_2210

Alternate gene names: 182679172

Gene position: 2535612-2534245 (Counterclockwise)

Preceding gene: 182679175

Following gene: 182679171

Centisome position: 60.8

GC content: 58.33

Gene sequence:

>1368_bases
ATGGCTGCTGGATTTCAGGGAGGCCTGGTTCAGGCCGCCAAGCGAACGGCCACGACGACCACGGGACGCGTCTTCGGCTT
GATCTGCTTGATGTATTTCATCACTTACGTCGACCGCGTGAATGTCTCGACTCTGGCGCCGTTGATGTCGAAGGAATTGG
GGCTTTCCAATATTCAACTCGGGTTGGTTCTCTCGGCTTTCGGCTATCCTTATGCGCTGTTGCAAATTCTCGGTGGCACC
GCGGCCGACAAATTTGGTGCGCGCAAAACCTTGACGATCTGCGGCGGCATCTGGGCTCTCTCCACGATCGCGACCGGATT
TGTCGGTGGTCTTTTCTCCTTGCTCCTGGTGCGGATTTTCGTCGGGATCGGCGAGGGCGCAACTTTTCCCGCCGCCACGC
GGGCGATGGCGTCCTGGGTACCGGAAAGCCGGCGCGGCTATGCACAGGGCATGGTTCATTCGGCTTCGCGTCTGGCCAAT
GCGATCACGCCGCCTCTGGTCATTCTCATCGCCGCCTATCTCGGCTGGCGCGGCGCCTTTCTGGCGCTTGGCTGCGTGAG
CATGGTTTGGGTCCTGGCCTGGCTTTTCTATTTCCGGGACAATCCTCGTGATCACACTGGGGTATCGTTGCAGGAAATCG
CGCTGCTGCCTGAGCCGCGACAGAAGACGCAGGCGGGCGCCGTGAAAGTGCCATGGGGACCTTTGACGCGCGCCATGATG
CCGACGACGCTCGTCTATTTCTGCTATAATTGGACATTCTGGCTCTATATCACCTGGCTACCGAGCTATTTCGTGCAGGC
CTATGGCCTCGAGCTGAAACATATGGCCGCTTTCACCTTCGCGATTTTTGCAGCCGGCGTCGTCGGTGACACATTGGGAG
GTGTGTTGACGGATTTCGTGTATCATCGGACGGGTGATCTTCCGGCGTCGCGTCGCCTTGTTGTCGTCTTCAGTCTCATC
GCTTCGATGATTTGCTTGATCCCGGCTTTGTTCGTGCACGATCTCGTGACGATCGGTTTCTCCTTGGCCTCGGCTTTCTT
CTTCCTTGAACTGACGGTTGGGCCGATCTGGGCGGTGCCCATGGATATTGCGCCCCATTTTTCGGGCACAGCCAGTGGCA
TCATGAACACGGGCTCGGCAATCGCCGGTATTGTGTCACCGATCGCTTTCGGCTTGGTGATCGATCTTACGCACAGCTAC
ACTTTGCCTTTCTATGGGTCGGTGCTGTTGTTGATGATCGGTGCCTGCATCGCCTTCTTCTTCATGCCGAGCCGAGGGCT
TGTCGCGTCTTCGGCCACCGAAAACGCGACGACGGGGCAGGCCAATTCGCCCAGGATCAGCACCATGCGGGATGTGGCCG
GCCAATGA

Upstream 100 bases:

>100_bases
GTCTGCCAGCCGCCGATTAGCACTAGAGGCTCTCGCGAAGGATCGGGGTGAAGCACCGGTCCGTATGACGAGACGACAAA
AATAAAGGCAGGAGAGGAAA

Downstream 100 bases:

>100_bases
GCACTAGACAGCAATCCATCCCATCTTCTGTCCTGGCAGGGCAGAGGAAATGGTCAGATGAAGAGGCGCGTGGATTCGTG
CGCCGTCTCTTTGATGCCGC

Product: major facilitator transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAAGFQGGLVQAAKRTATTTTGRVFGLICLMYFITYVDRVNVSTLAPLMSKELGLSNIQLGLVLSAFGYPYALLQILGGT
AADKFGARKTLTICGGIWALSTIATGFVGGLFSLLLVRIFVGIGEGATFPAATRAMASWVPESRRGYAQGMVHSASRLAN
AITPPLVILIAAYLGWRGAFLALGCVSMVWVLAWLFYFRDNPRDHTGVSLQEIALLPEPRQKTQAGAVKVPWGPLTRAMM
PTTLVYFCYNWTFWLYITWLPSYFVQAYGLELKHMAAFTFAIFAAGVVGDTLGGVLTDFVYHRTGDLPASRRLVVVFSLI
ASMICLIPALFVHDLVTIGFSLASAFFFLELTVGPIWAVPMDIAPHFSGTASGIMNTGSAIAGIVSPIAFGLVIDLTHSY
TLPFYGSVLLLMIGACIAFFFMPSRGLVASSATENATTGQANSPRISTMRDVAGQ

Sequences:

>Translated_455_residues
MAAGFQGGLVQAAKRTATTTTGRVFGLICLMYFITYVDRVNVSTLAPLMSKELGLSNIQLGLVLSAFGYPYALLQILGGT
AADKFGARKTLTICGGIWALSTIATGFVGGLFSLLLVRIFVGIGEGATFPAATRAMASWVPESRRGYAQGMVHSASRLAN
AITPPLVILIAAYLGWRGAFLALGCVSMVWVLAWLFYFRDNPRDHTGVSLQEIALLPEPRQKTQAGAVKVPWGPLTRAMM
PTTLVYFCYNWTFWLYITWLPSYFVQAYGLELKHMAAFTFAIFAAGVVGDTLGGVLTDFVYHRTGDLPASRRLVVVFSLI
ASMICLIPALFVHDLVTIGFSLASAFFFLELTVGPIWAVPMDIAPHFSGTASGIMNTGSAIAGIVSPIAFGLVIDLTHSY
TLPFYGSVLLLMIGACIAFFFMPSRGLVASSATENATTGQANSPRISTMRDVAGQ
>Mature_454_residues
AAGFQGGLVQAAKRTATTTTGRVFGLICLMYFITYVDRVNVSTLAPLMSKELGLSNIQLGLVLSAFGYPYALLQILGGTA
ADKFGARKTLTICGGIWALSTIATGFVGGLFSLLLVRIFVGIGEGATFPAATRAMASWVPESRRGYAQGMVHSASRLANA
ITPPLVILIAAYLGWRGAFLALGCVSMVWVLAWLFYFRDNPRDHTGVSLQEIALLPEPRQKTQAGAVKVPWGPLTRAMMP
TTLVYFCYNWTFWLYITWLPSYFVQAYGLELKHMAAFTFAIFAAGVVGDTLGGVLTDFVYHRTGDLPASRRLVVVFSLIA
SMICLIPALFVHDLVTIGFSLASAFFFLELTVGPIWAVPMDIAPHFSGTASGIMNTGSAIAGIVSPIAFGLVIDLTHSYT
LPFYGSVLLLMIGACIAFFFMPSRGLVASSATENATTGQANSPRISTMRDVAGQ

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=387, Percent_Identity=27.390180878553, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI9966811, Length=396, Percent_Identity=25.7575757575758, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI154350196, Length=418, Percent_Identity=23.9234449760766, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI9945322, Length=357, Percent_Identity=24.3697478991597, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI21322234, Length=412, Percent_Identity=23.3009708737864, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4885441, Length=401, Percent_Identity=23.9401496259352, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789152, Length=438, Percent_Identity=31.7351598173516, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789515, Length=411, Percent_Identity=28.9537712895377, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87082320, Length=392, Percent_Identity=30.3571428571429, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI2367379, Length=413, Percent_Identity=28.8135593220339, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI2367193, Length=294, Percent_Identity=27.5510204081633, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788068, Length=449, Percent_Identity=23.162583518931, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=406, Percent_Identity=26.8472906403941, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17535049, Length=393, Percent_Identity=24.6819338422392, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115533556, Length=371, Percent_Identity=25.8760107816712, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115533554, Length=371, Percent_Identity=25.8760107816712, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17557432, Length=230, Percent_Identity=26.5217391304348, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI115534564, Length=230, Percent_Identity=26.5217391304348, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193205400, Length=206, Percent_Identity=26.6990291262136, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17554148, Length=363, Percent_Identity=24.7933884297521, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532009, Length=241, Percent_Identity=24.4813278008299, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=241, Percent_Identity=23.6514522821577, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=241, Percent_Identity=23.6514522821577, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560966, Length=196, Percent_Identity=23.9795918367347, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561498, Length=229, Percent_Identity=24.4541484716157, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24641682, Length=427, Percent_Identity=26.2295081967213, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24580790, Length=348, Percent_Identity=25.2873563218391, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI45550460, Length=452, Percent_Identity=24.3362831858407, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24648416, Length=445, Percent_Identity=23.5955056179775, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21356189, Length=445, Percent_Identity=23.5955056179775, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24584153, Length=352, Percent_Identity=23.5795454545455, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655255, Length=404, Percent_Identity=24.009900990099, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639764, Length=381, Percent_Identity=23.6220472440945, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI19922400, Length=370, Percent_Identity=25.1351351351351, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24654215, Length=370, Percent_Identity=25.1351351351351, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI20130135, Length=418, Percent_Identity=23.2057416267943, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24655271, Length=418, Percent_Identity=23.2057416267943, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI62484226, Length=403, Percent_Identity=25.8064516129032, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573299, Length=390, Percent_Identity=23.8461538461538, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573708, Length=382, Percent_Identity=23.0366492146597, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573707, Length=382, Percent_Identity=23.0366492146597, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583789, Length=351, Percent_Identity=24.7863247863248, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24658666, Length=433, Percent_Identity=21.4780600461894, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45550495, Length=449, Percent_Identity=22.4944320712695, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920686, Length=413, Percent_Identity=22.2760290556901, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24658658, Length=469, Percent_Identity=21.3219616204691, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24658674, Length=415, Percent_Identity=21.6867469879518, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24658696, Length=423, Percent_Identity=23.6406619385343, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129235, Length=341, Percent_Identity=28.4457478005865, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20130167, Length=346, Percent_Identity=22.5433526011561, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281361682, Length=365, Percent_Identity=22.1917808219178, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24653727, Length=403, Percent_Identity=21.8362282878412, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221474708, Length=379, Percent_Identity=22.1635883905013, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48819; Mature: 48688

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
AAGFQGGLVQAAKRTATTTTGRVFGLICLMYFITYVDRVNVSTLAPLMSKELGLSNIQL
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH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HCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9772162; 10762278 [H]