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The map label for this gene is ttuD [H]

Identifier: 182679171

GI number: 182679171

Start: 2532914

End: 2534248

Strand: Reverse

Name: ttuD [H]

Synonym: Bind_2209

Alternate gene names: 182679171

Gene position: 2534248-2532914 (Counterclockwise)

Preceding gene: 182679172

Following gene: 182679170

Centisome position: 60.77

GC content: 62.85

Gene sequence:

>1335_bases
ATGAGCACTAGACAGCAATCCATCCCATCTTCTGTCCTGGCAGGGCAGAGGAAATGGTCAGATGAAGAGGCGCGTGGATT
CGTGCGCCGTCTCTTTGATGCCGCCGTCGCTTCGGCCGATCCGCTGCATGTTCTGGCAGCGCATTTGCCCGATCCACCCC
GCTTGGGGCGCTGTGTCGTGGTTGGCGCGGGCAAATCGGCTGCCACAATGGCTGCCGCTTTGGAACGGGCTTGGCCCGAC
GTGGACCTTTCGGGCCTCGTCGTGACCCGTTACGGCCATGCGGTCCCCACCCAGCGGATCGAAGTGATCGAAGCTGCCCA
TCCCGTCCCCGATGACCGCAGTGAACATGCCGCGCGACGCATGCTCGCCGCCGTTTCCGGCCTGAAAGAAGGCGATCTAG
TGATCGCGCTGATCTCCGGCGGAGGCTCGTCGTTGCTGGCTCTTCCCCGGCCGGGCTTGAGCCTTGCCGATAAGCAGGCC
GTCAACCGTGCTTTGCTGCATAGCGGTGCGACCATCGCGGAAATGAATCTCATCCGCAAGCAATTGTCGGCGATCAAGGG
CGGTAGGCTCGCCGCTGCCGCCGCGCCGGCGCGCGTTATGACGCTCGCCATCAGTGACGTGCCAGGGGACGATCCGGCAA
CTATTGCCAGCGGGCCGACCGTGCCCGAACGCTTTGACGCCGAGGCTATTGGCGAAATTTTGGCGCGCTACAAGCTGGAT
CTGCCACCGCATGTGATGAAGGCATTGAGTGATGGGCCTGCCGGACGACCGGCGCTTAACGATCTGCCACCCGTCGATTT
CAGGATGATCGCCACTCCGGCCATGGCGCTTGCGGCTTGCGCGGCCACGGCGCGGGCTCATGGCGTGACGCCGATCATTC
TTGGCGATGCGCTGGAAGGTGAAAGCCGCGAGGTCGGGACGGTCATGGCCGGGATTGCCCGCAGTGTGAGGGATTATGGT
CAGCCGGTTGAGGCTCCCGCCGTGCTTTTGTCAGGCGGTGAGACGACGGTTTCGATCGGTATGACCCCTCCTGGCCGTGG
GGGACGCAACACGGAATTCCTGGCGGGGCTCGCGGTCGCTTTGGCTGGTGCGCGCGGCATTTGGGCCATTGCGGGGGATA
CGGATGGCATTGATGGGACGGAAGATGCGGCGGGCGCTATCGTTGCGCCCGATACATTGATCCGCGCCGAGGCGAAGGGG
TTGAATGCGCGCGACTATCTCTCGCGCCATGATAGCTATTCATTGTTTCAGGCCCTCGGGGATCTGGTCGTGACGGGTCC
GACCTTGACCAATGTCAACGATATCCGTGCCATCTTAATCATGCCGAAGGGATAA

Upstream 100 bases:

>100_bases
TGCCGAGCCGAGGGCTTGTCGCGTCTTCGGCCACCGAAAACGCGACGACGGGGCAGGCCAATTCGCCCAGGATCAGCACC
ATGCGGGATGTGGCCGGCCA

Downstream 100 bases:

>100_bases
TCGGCGATGGCCATTCTTGATTCCCGCGTGGATGAGGCTAGATCAATTCCGTGCGAGCAGCATCGGCCGTCTCGTCATTT
CAAACAACGGCAGGAAACAG

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSTRQQSIPSSVLAGQRKWSDEEARGFVRRLFDAAVASADPLHVLAAHLPDPPRLGRCVVVGAGKSAATMAAALERAWPD
VDLSGLVVTRYGHAVPTQRIEVIEAAHPVPDDRSEHAARRMLAAVSGLKEGDLVIALISGGGSSLLALPRPGLSLADKQA
VNRALLHSGATIAEMNLIRKQLSAIKGGRLAAAAAPARVMTLAISDVPGDDPATIASGPTVPERFDAEAIGEILARYKLD
LPPHVMKALSDGPAGRPALNDLPPVDFRMIATPAMALAACAATARAHGVTPIILGDALEGESREVGTVMAGIARSVRDYG
QPVEAPAVLLSGGETTVSIGMTPPGRGGRNTEFLAGLAVALAGARGIWAIAGDTDGIDGTEDAAGAIVAPDTLIRAEAKG
LNARDYLSRHDSYSLFQALGDLVVTGPTLTNVNDIRAILIMPKG

Sequences:

>Translated_444_residues
MSTRQQSIPSSVLAGQRKWSDEEARGFVRRLFDAAVASADPLHVLAAHLPDPPRLGRCVVVGAGKSAATMAAALERAWPD
VDLSGLVVTRYGHAVPTQRIEVIEAAHPVPDDRSEHAARRMLAAVSGLKEGDLVIALISGGGSSLLALPRPGLSLADKQA
VNRALLHSGATIAEMNLIRKQLSAIKGGRLAAAAAPARVMTLAISDVPGDDPATIASGPTVPERFDAEAIGEILARYKLD
LPPHVMKALSDGPAGRPALNDLPPVDFRMIATPAMALAACAATARAHGVTPIILGDALEGESREVGTVMAGIARSVRDYG
QPVEAPAVLLSGGETTVSIGMTPPGRGGRNTEFLAGLAVALAGARGIWAIAGDTDGIDGTEDAAGAIVAPDTLIRAEAKG
LNARDYLSRHDSYSLFQALGDLVVTGPTLTNVNDIRAILIMPKG
>Mature_443_residues
STRQQSIPSSVLAGQRKWSDEEARGFVRRLFDAAVASADPLHVLAAHLPDPPRLGRCVVVGAGKSAATMAAALERAWPDV
DLSGLVVTRYGHAVPTQRIEVIEAAHPVPDDRSEHAARRMLAAVSGLKEGDLVIALISGGGSSLLALPRPGLSLADKQAV
NRALLHSGATIAEMNLIRKQLSAIKGGRLAAAAAPARVMTLAISDVPGDDPATIASGPTVPERFDAEAIGEILARYKLDL
PPHVMKALSDGPAGRPALNDLPPVDFRMIATPAMALAACAATARAHGVTPIILGDALEGESREVGTVMAGIARSVRDYGQ
PVEAPAVLLSGGETTVSIGMTPPGRGGRNTEFLAGLAVALAGARGIWAIAGDTDGIDGTEDAAGAIVAPDTLIRAEAKGL
NARDYLSRHDSYSLFQALGDLVVTGPTLTNVNDIRAILIMPKG

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=443, Percent_Identity=33.8600451467269, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI193205461, Length=353, Percent_Identity=34.2776203966006, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI19920578, Length=439, Percent_Identity=27.7904328018223, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 45856; Mature: 45725

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRQQSIPSSVLAGQRKWSDEEARGFVRRLFDAAVASADPLHVLAAHLPDPPRLGRCVV
CCCCHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEE
VGAGKSAATMAAALERAWPDVDLSGLVVTRYGHAVPTQRIEVIEAAHPVPDDRSEHAARR
EECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
MLAAVSGLKEGDLVIALISGGGSSLLALPRPGLSLADKQAVNRALLHSGATIAEMNLIRK
HHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
QLSAIKGGRLAAAAAPARVMTLAISDVPGDDPATIASGPTVPERFDAEAIGEILARYKLD
HHHHHCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
LPPHVMKALSDGPAGRPALNDLPPVDFRMIATPAMALAACAATARAHGVTPIILGDALEG
CCHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
ESREVGTVMAGIARSVRDYGQPVEAPAVLLSGGETTVSIGMTPPGRGGRNTEFLAGLAVA
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHH
LAGARGIWAIAGDTDGIDGTEDAAGAIVAPDTLIRAEAKGLNARDYLSRHDSYSLFQALG
HHCCCCEEEEECCCCCCCCCCCCCCEEECCCHHHHHHHCCCCHHHHHHHCCCHHHHHHHH
DLVVTGPTLTNVNDIRAILIMPKG
HHEECCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
STRQQSIPSSVLAGQRKWSDEEARGFVRRLFDAAVASADPLHVLAAHLPDPPRLGRCVV
CCCHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEE
VGAGKSAATMAAALERAWPDVDLSGLVVTRYGHAVPTQRIEVIEAAHPVPDDRSEHAARR
EECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
MLAAVSGLKEGDLVIALISGGGSSLLALPRPGLSLADKQAVNRALLHSGATIAEMNLIRK
HHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
QLSAIKGGRLAAAAAPARVMTLAISDVPGDDPATIASGPTVPERFDAEAIGEILARYKLD
HHHHHCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
LPPHVMKALSDGPAGRPALNDLPPVDFRMIATPAMALAACAATARAHGVTPIILGDALEG
CCHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
ESREVGTVMAGIARSVRDYGQPVEAPAVLLSGGETTVSIGMTPPGRGGRNTEFLAGLAVA
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHH
LAGARGIWAIAGDTDGIDGTEDAAGAIVAPDTLIRAEAKGLNARDYLSRHDSYSLFQALG
HHCCCCEEEEECCCCCCCCCCCCCCEEECCCHHHHHHHCCCCHHHHHHHCCCHHHHHHHH
DLVVTGPTLTNVNDIRAILIMPKG
HHEECCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]