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The map label for this gene is clpX [H]

Identifier: 182679146

GI number: 182679146

Start: 2494641

End: 2495906

Strand: Reverse

Name: clpX [H]

Synonym: Bind_2183

Alternate gene names: 182679146

Gene position: 2495906-2494641 (Counterclockwise)

Preceding gene: 182679147

Following gene: 182679145

Centisome position: 59.85

GC content: 55.53

Gene sequence:

>1266_bases
ATGACAAAGGTCGGCGGCAGCGACTCCAAGAACACGCTTTATTGCTCGTTCTGTGGCAAGAGCCAACATGAGGTCCGCAA
GCTGATTGCCGGTCCCACCGTCTTCATTTGCGATGAATGCGTCGAACTCTGCATGGATATCATTCGCGAGGAAAACAAAT
CCTCGCTGGTCAAGAGCCGGGATGGAATTCCGACGCCGCGTGAAATCTGCAAGGTCCTCGATGATTATGTCATCGGCCAG
CCGCAGGCGAAGCGTGTGCTCTCGGTCGCAGTTCATAATCATTACAAACGGCTCAATCATGCCACCAAGCATAATGATGT
TGAGCTTGCGAAATCCAATATCCTGCTGATCGGCCCGACCGGTTCCGGCAAGACCTTGCTGGCGCAGACGCTGGCTCGCA
TCCTCGATGTTCCTTTCACCATGGCCGATGCGACGACGCTCACCGAAGCTGGCTATGTCGGTGAGGATGTTGAGAACATT
ATCCTCAAGCTTCTGCAGGCCTCCGACTACAATGTCGAACGGGCGCAGCGTGGCATTGTCTATATCGATGAAATCGACAA
GATTTCCCGCAAGTCGGATAATCCGTCGATCACGCGCGATGTCTCTGGCGAAGGTGTGCAGCAGGCCCTGTTGAAGATCA
TGGAGGGCACCGTTGCTTCCGTGCCTCCGCAGGGCGGTCGCAAACATCCGCAGCAGGAATTCCTGCAGGTCGATACGACG
AATATTTTGTTCATCTGCGGTGGTGCATTCGCCGGTCTCGAAAAGATCATTTCGACTCGCGGCAAGACCACGTCGATCGG
TTTCGCTGCCAGCGTGCAGGCACCGGATGACCGGCGCACGGGCGAAATCTTCCGCAAGGTCGAGCCCGAGGATCTACTGA
AATTCGGCCTCATCCCCGAATTTGTCGGACGTCTGCCGGTCATCGCCACGTTGGAAGATCTCGACGAGGAGGCCCTGAAA
AAGATCCTCACCGAGCCGAAGAACGCGCTTGTCAAGCAATATCAGCGCCTCTTCGAAATGGAGAACACCGAACTCACCTT
CCAGGACGAGGCGCTGAATGTCGTCGCCAAAAAGGCGATCGAACGGAAAACCGGTGCGCGTGGTTTGCGCTCCATCATGG
AGAGCATATTGCTCGATACGATGTTTGATCTGCCGGGTCTCGATAGTGTCGAGCAGGTCGTCATCGGTCCGGATGTCGTC
GAGGGTAAATCGCGGCCGCTCTACATTTATGCCGAGCGCAACGAAAAGAGTGGCACGAGTGCTTGA

Upstream 100 bases:

>100_bases
GGATCCACCGGCCATGGTGACGATGCCAGCCATTTTCATCATGATCCTAATTCACCATGATCGAGGTCCGCACATGGCCT
CGGCCGTTAGGAGATGATCC

Downstream 100 bases:

>100_bases
TTGCAAGCCCGCTCTCTTGCGCGGGCTTGCCAACAAGAAAAAGCGCGGATCTTGGTCCGCGCTGGCTAACAGAACCCAAG
AGTCTTCTTGAAACGGTTCT

Product: ATP-dependent Clp protease, ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTKVGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPREICKVLDDYVIGQ
PQAKRVLSVAVHNHYKRLNHATKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLEKIISTRGKTTSIGFAASVQAPDDRRTGEIFRKVEPEDLLKFGLIPEFVGRLPVIATLEDLDEEALK
KILTEPKNALVKQYQRLFEMENTELTFQDEALNVVAKKAIERKTGARGLRSIMESILLDTMFDLPGLDSVEQVVIGPDVV
EGKSRPLYIYAERNEKSGTSA

Sequences:

>Translated_421_residues
MTKVGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPREICKVLDDYVIGQ
PQAKRVLSVAVHNHYKRLNHATKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLEKIISTRGKTTSIGFAASVQAPDDRRTGEIFRKVEPEDLLKFGLIPEFVGRLPVIATLEDLDEEALK
KILTEPKNALVKQYQRLFEMENTELTFQDEALNVVAKKAIERKTGARGLRSIMESILLDTMFDLPGLDSVEQVVIGPDVV
EGKSRPLYIYAERNEKSGTSA
>Mature_420_residues
TKVGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPREICKVLDDYVIGQP
QAKRVLSVAVHNHYKRLNHATKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLEKIISTRGKTTSIGFAASVQAPDDRRTGEIFRKVEPEDLLKFGLIPEFVGRLPVIATLEDLDEEALKK
ILTEPKNALVKQYQRLFEMENTELTFQDEALNVVAKKAIERKTGARGLRSIMESILLDTMFDLPGLDSVEQVVIGPDVVE
GKSRPLYIYAERNEKSGTSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=340, Percent_Identity=52.9411764705882, Blast_Score=333, Evalue=1e-91,
Organism=Escherichia coli, GI1786642, Length=423, Percent_Identity=71.6312056737589, Blast_Score=607, Evalue=1e-175,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=46.2264150943396, Blast_Score=98, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=319, Percent_Identity=47.0219435736677, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71982905, Length=319, Percent_Identity=47.0219435736677, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=38.9312977099237, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=39.6, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=418, Percent_Identity=38.9952153110048, Blast_Score=263, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24648289, Length=333, Percent_Identity=50.1501501501502, Blast_Score=311, Evalue=7e-85,
Organism=Drosophila melanogaster, GI24648291, Length=333, Percent_Identity=50.1501501501502, Blast_Score=311, Evalue=7e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46405; Mature: 46274

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHC
DGIPTPREICKVLDDYVIGQPQAKRVLSVAVHNHYKRLNHATKHNDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHEECCC
NILFICGGAFAGLEKIISTRGKTTSIGFAASVQAPDDRRTGEIFRKVEPEDLLKFGLIPE
CEEEEECCHHHHHHHHHHCCCCCEECCEEEECCCCCCCHHHHHHHHCCHHHHHHHCCCHH
FVGRLPVIATLEDLDEEALKKILTEPKNALVKQYQRLFEMENTELTFQDEALNVVAKKAI
HHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
ERKTGARGLRSIMESILLDTMFDLPGLDSVEQVVIGPDVVEGKSRPLYIYAERNEKSGTS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCCCCCCCEEEEEECCCCCCCC
A
C
>Mature Secondary Structure 
TKVGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSR
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHC
DGIPTPREICKVLDDYVIGQPQAKRVLSVAVHNHYKRLNHATKHNDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHEECCC
NILFICGGAFAGLEKIISTRGKTTSIGFAASVQAPDDRRTGEIFRKVEPEDLLKFGLIPE
CEEEEECCHHHHHHHHHHCCCCCEECCEEEECCCCCCCHHHHHHHHCCHHHHHHHCCCHH
FVGRLPVIATLEDLDEEALKKILTEPKNALVKQYQRLFEMENTELTFQDEALNVVAKKAI
HHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
ERKTGARGLRSIMESILLDTMFDLPGLDSVEQVVIGPDVVEGKSRPLYIYAERNEKSGTS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCCCCCCCEEEEEECCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA